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Downstream Process Jobs in Michigan (NOW HIRING)

Wright Technical Services

Process Engineer

Macomb, MI · On-site

Support in technical training of Sales & Estimation and downstream process teams. * Help identify engineering & key technical organizational capability improvement opportunities. Provide guidance and ...

Stryker

Material Resource Planner (Hybrid)

Kalamazoo, MI · Hybrid

$66K - $101K/yr

You will collaborate with up and downstream process partners who impact inventory to ensure inventory levels are optimized, using approved PFEP and other tools to support the needs of the business.

Stryker

Material Resource Planner (Hybrid)

Kalamazoo, MI · On-site

$66K - $101K/yr

You will collaborate with up and downstream process partners who impact inventory to ensure inventory levels are optimized, using approved PFEP and other tools to support the needs of the business.

Dicastal North America

Process Engineer

Livonia, MI · On-site

The primary focus of this role is casting simulation, trial validation, and process optimization, while also supporting downstream machining and assembly operations to ensure seamless product ...

Tech Tammina LLC

AI Engineer/ Developer

Okemos, MI · On-site

... for downstream processing or inference • Collaborate with cross-functional teams to iterate on design, functionality, and performance • Use Git and collaborative development tools to manage and ...

AK Steel

Process Control Engineer

Warren, MI · On-site

... downstream finishing, stamping, tooling, and tubing. We offer an excellent total compensation ... process, please send an e-mail tocareers@clevelandcliffs.comor call 1-(312) 899-3097 and let us ...

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Downstream Process information

What are some common challenges faced by professionals working in downstream process roles within biomanufacturing?

Professionals in downstream process roles often encounter challenges such as optimizing purification steps to maximize yield and product purity while minimizing costs and processing time. They must also troubleshoot issues related to equipment performance, scalability, and regulatory compliance, especially when transitioning from lab-scale to large-scale production. Collaboration with upstream teams, quality assurance, and engineering is critical to address these challenges and ensure a smooth workflow. Staying current with technological advances and regulatory requirements also plays a significant role in day-to-day success.

What are the key skills and qualifications needed to thrive as a Downstream Process Engineer, and why are they important?

To thrive as a Downstream Process Engineer, you need a solid background in chemical or biochemical engineering, knowledge of purification techniques, and typically a relevant degree. Familiarity with process control systems, chromatography, filtration technologies, and GMP compliance, as well as certifications like Six Sigma, are commonly required. Strong problem-solving, teamwork, and communication skills help you excel in cross-functional teams and address complex production challenges. These skills ensure efficient, high-quality product recovery and compliance with industry standards in biomanufacturing environments.

What is the difference between Downstream Process vs Upstream Process?

AspectDownstream ProcessUpstream Process
PurposePurifies and isolates the target product from the mixtureProduces the initial product, such as cell culture or fermentation
ActivitiesFiltration, chromatography, centrifugation, purificationCell growth, fermentation, media preparation
Work EnvironmentLaboratories, bioprocessing facilitiesBioreactors, fermentation tanks, labs
Required SkillsBioprocessing techniques, chromatography, filtrationMicrobiology, cell culture, fermentation technology

Downstream Process focuses on purifying the product, while Upstream Process involves producing the raw material. Both are essential steps in biopharmaceutical manufacturing, often working sequentially to ensure high-quality product output.

What is a Downstream Process in biotechnology?

A Downstream Process refers to the series of steps involved in the purification and recovery of biological products, such as proteins, enzymes, or antibodies, after they have been produced by microorganisms or cells during fermentation or cell culture. It typically includes cell separation, product isolation, purification, and polishing to achieve the desired product quality and purity. Downstream processing is crucial for ensuring that biopharmaceutical products meet regulatory and safety standards before they reach the market.
What are popular job titles related to Downstream Process jobs in Michigan? For Downstream Process jobs in Michigan, the most frequently searched job titles are:
What job categories do people searching Downstream Process jobs in Michigan look for? The top searched job categories for Downstream Process jobs in Michigan are:
Downstream Process jobs near you
Infographic showing various Downstream Process job openings in Michigan as of July 2026, with employment types broken down into 18% Locum Tenens, 74% Full Time, 4% Part Time, 3% Contract, and 1% Summer. Highlights an 85% Physical, 4% Hybrid, and 11% Remote job distribution.

Process Engineer

Wright Technical Services

Macomb, MI

Full-time

Re-posted 16 days ago

Job description

Title: Process Engineer
Job Type: Permanent/Direct Hire
Location: Macomb, MI
Onsite/Travel Requirements: Full-Time Onsite
Eligibility: This role is not open to current or future sponsorship, or C2C partnerships

Job Description

This role will lead the process & manufacturing engineering functions in our client's Government, Aerospace, and Defense Solutions (GADS) business unit for aerospace-type hardware applications. This role is influential for increasing customer confidence in GADS manufacturing capabilities and leads the conversion of technical & contract requirements into robust, repeatable, and efficient manufacturing processes that comply with AS9100, customer requirements, and flight-critical quality standards.

Qualifications

Required

  • 4-year degree in an Engineering discipline required (Mechanical, Industrial, or related)
  • At least 5 years in aerospace-type critical parts manufacturing.

Preferred

  • At least 8-10 years of experience in manufacturing, ideally CNC machining-centric operations. Preference for understanding of machining processes for materials like titanium & Inconel. Knowledge of fixtures & tooling for machining preferred.
  • Proven track record of increasing individual responsibilities and developmental success of your team members.
  • Computer proficiency, including M365, project management software, CAD competency (CAM, Vericut/simulation & 3D modeling a plus), also able to read blueprints and GD&T.
  • Experience with SPC, statistical analysis, and continuous improvement methodologies (Lean, Six Sigma).
  • Effective writing and communication skills, able to explain complex issues to a wide array of audiences. Preference for experience with 3rd party audits..

Key Responsibilities

Process Development & Documentation

  • Lead, prepare, and implement manufacturing requirements necessary to meet customer requirements, including for Part Qualification/Re-Qualification, PFMEA, Control Plans, First Articles, etc.
  • Work with machining/tooling planners to define machining sequences, datums, cutting strategies, and in-process inspection requirements.
  • Ensure risk mitigation is accounted for during process development to meet internal and external requirements.
  • Partner with Quality on APQP and MSA/GR&R.

Continuous Improvement & Optimization

  • Develop, industrialize, and improve manufacturing processes for aerospace-type hardware applications.
  • Use manufacturing data to manage process control, develop & implement process improvement including creating and updating work instructions.
  • Champion wide-ranging organizational improvement efforts leveraging company standard Continuous Improvement resources including tools, processes, and corporate experts.

Technical Support, Troubleshooting, and Leadership

  • Coordinate multiple projects of med-high complexity and risk, including multiple sub-projects, and comprised of cross-functional and/or multi-site project team members.
  • Assist Quality with MRB root cause analysis and technically sound repair planning.
  • Support in technical training of Sales & Estimation and downstream process teams.
  • Help identify engineering & key technical organizational capability improvement opportunities. Provide guidance and support to lower-level engineers and other technical roles.
  • Maintains and actively supports improving safety of operations, adheres to safety procedures and regulations.
  • Additional job duties as assigned

Wright Technical Services and our client are Equal Opportunity Employers. We celebrate diversity and are committed to creating an inclusive environment for all employees. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or veteran status.