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Downstream Process Development Jobs in New York (NOW HIRING)

Manager, Process Operations

Rahway, NJ

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

The Biologics Process Research & Development organization within our Company Research Labs is ... Job Responsibilities: * Lead a team executing upstream and downstream production operations.

Manager, Process Operations

Rahway, NJ · On-site

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

The Biologics Process Research & Development organization within our Company Research Labs is ... Job Responsibilities: * Lead a team executing upstream and downstream production operations.

Manager, Process Operations

Rahway, NJ · On-site

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

The Biologics Process Research & Development organization within our Company Research Labs is ... Lead a team executing upstream and downstream production operations.Assign daily work and ensure ...

Showing results 41-60

Downstream Process Development information

What is downstream process development?

A Downstream Process Development job involves optimizing and scaling purification processes for biologics, such as proteins, antibodies, or gene therapies. Scientists and engineers in this role develop efficient methods for isolation, purification, and formulation of therapeutic products while ensuring quality and regulatory compliance. Key activities include chromatography, filtration, and process analytics to improve yield, purity, and consistency. This role is critical in biotech and pharmaceutical industries to ensure safe and effective drug production for clinical and commercial use.

What does someone in downstream process development do?

Professionals in Downstream Process Development are typically responsible for designing, optimizing, and scaling up purification processes for biopharmaceutical products. Their day-to-day work may involve conducting laboratory experiments, analyzing data, troubleshooting technical issues, and documenting process changes in accordance with regulatory standards. They also frequently collaborate with upstream processing, analytical, and quality teams to ensure seamless transfer and integration of processes. The role often includes participating in project meetings, contributing to process validation efforts, and supporting technology transfer to manufacturing teams, making it both technically challenging and collaborative.

What are the key skills and qualifications needed for downstream process development?

To excel in Downstream Process Development, you generally need a strong background in biochemistry, chemical engineering, or a related life sciences field, often with experience in bioprocessing or purification technologies. Familiarity with chromatography systems, filtration equipment, process analytical technology (PAT), and relevant software such as DeltaV or Unicorn is frequently required, along with knowledge of GMP and regulatory standards. Excellent problem-solving, project management, and cross-functional communication skills help professionals succeed in dynamic team environments. These competencies are crucial for developing efficient, scalable purification processes that ensure high product quality and support organizational goals.

What are the most commonly searched types of Downstream Process Development jobs in New York?

The most popular types of Downstream Process Development jobs in New York are:

What job categories do people searching Downstream Process Development jobs in New York look for?

The top searched job categories for Downstream Process Development jobs in New York are:

What cities in New York are hiring for Downstream Process Development jobs?

Cities in New York with the most Downstream Process Development job openings:

Infographic showing various Downstream Process Development job openings in New York as of August 2026, with employment types broken down into 1% As Needed, 81% Full Time, 16% Part Time, and 2% Contract. Highlights an 90% Physical, 3% Hybrid, and 7% Remote job distribution.

Process Development Engineer I, Purification Development

Regeneron Pharmaceuticals

Tarrytown, NY

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 24 days ago


Regeneron rating

8.4

Company rating: 8.4 out of 10

Based on 43 frontline employees who took The Breakroom Quiz

22nd of 86 rated pharmaceutical


Job description

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. Regeneron is currently seeking a Process Development Engineer to join our PMPD team. In this role, you will be responsible for the purification of various pre-clinical biological molecules to provide reagents and therapeutics for Regeneron's research and discovery groups. The ideal candidate will be hardworking, efficient, flexible, and able to perform key responsibilities in a fast-paced, team environment.

This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

When & where:
  • Shift Requirements: Full-time, standard business hours, with flexibility to support before- and after-hours
  • Location: On-Site in Tarrytown, NY
  • Flexibility & travel: Some travel required. Must be available on-site consistently, including to maintain coverage during staff absences
What you'll do:
  • Purification of a diverse array of proteins to support many of Regeneron's research and discovery groups
  • Process development for clinical processes
  • Development of technology and automation to increase process throughput and efficiency of preclinical manufacturing
  • Documentation of experiments, results, and findings in an electronic laboratory notebook; presentation of work at group and department meetings.
  • Maintenance of instruments and troubleshooting of instrumental/experimental problems
  • Collaboration with peers to complete core deliverables while exhibiting independence in experimental execution and troubleshooting
The environment and physical rhythms of this role:
  • A fast-paced pilot scale laboratory setting where sound science and team work are priorities.
  • Contribute to lab equipment maintenance and safety to help create a safe, effective, and efficient working environment.
  • Anticipate and recognize potential problems with laboratory supplies / equipment and act to prevent and tackle problems.
Let's find out if we're a fit:

The role requires a Bachelors degree in either Chemical Engineering, Biochemical Engineering, or Biochemistry, and 3+ years' or a MS and 0-3 years of experience in the biotech or pharmaceutical industry. A strong fundamental understanding of various protein purification techniques a plus. Experience with Downstream Development and with equipment like Akta Explorers/Avants/Pilots, chromatography columns, tangential flow filters, depth filters, HPLCs, and UPLCs as well as software such as Empower, Unicorn, JMP, and LIMS is a plus. Job will periodically require short duration physical exertions, including light-medium weight lifting.

Thrive today. Grow tomorrow.
  • Student Loan Paydown program & Tuition Reimbursement
  • Family Care Benefits
  • Relocation Assistance
  • Inclusion, Culture and Well-Being programs (including physical & mental health)

#pmpd

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process. If you have any questions, please speak with your recruiter.


Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed onsite. Please speak with your recruiter and hiring manager for more information about onsite expectations for your role and location.


As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.


For jobs in Canada: this posting is for an existing position.


Salary Range (annually)

$80,300.00 - $131,100.00

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