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Downstream Process Development Jobs in Massachusetts

AbbVie

Senior Scientist II Process Development

Worcester, MA

$91K - $124K/yr

The core deliverable of downstream team is to develop robust manufacturing processes and advance ... Lead development, optimization, scale-up, and tech transfer of purification processes for biologics ...

AbbVie

Senior Scientist II Process Development

Worcester, MA

$91K - $124K/yr

The core deliverable of downstream team is to develop robust manufacturing processes and advance ... Lead development, optimization, scale-up, and tech transfer of purification processes for biologics ...

Access Vascular

MA

$110K - $145K/yr

The Sr. Process Development Engineer will provide technical leadership in the innovation, design ... to reduce downstream transfer risk and accelerate time to production readiness · Establish ...

AbbVie

Global Process Engineer - Biologics

Worcester, MA · On-site

$124K/yr

The Global Biologics upstream and downstream Process Engineer will support the AbbVie Technical ... The selected candidate will contribute to the development of new principles and concepts and is ...

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Downstream Process Development information

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$20

$36

$54

How much do downstream process development jobs pay per hour?

As of Jun 27, 2026, the average hourly pay for downstream process development in Massachusetts is $36.79, according to ZipRecruiter salary data. Most workers in this role earn between $30.19 and $45.14 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in the Downstream Process Development position, and why are they important?

To excel in Downstream Process Development, you generally need a strong background in biochemistry, chemical engineering, or a related life sciences field, often with experience in bioprocessing or purification technologies. Familiarity with chromatography systems, filtration equipment, process analytical technology (PAT), and relevant software such as DeltaV or Unicorn is frequently required, along with knowledge of GMP and regulatory standards. Excellent problem-solving, project management, and cross-functional communication skills help professionals succeed in dynamic team environments. These competencies are crucial for developing efficient, scalable purification processes that ensure high product quality and support organizational goals.

What is a Downstream Process Development job?

A Downstream Process Development job involves optimizing and scaling purification processes for biologics, such as proteins, antibodies, or gene therapies. Scientists and engineers in this role develop efficient methods for isolation, purification, and formulation of therapeutic products while ensuring quality and regulatory compliance. Key activities include chromatography, filtration, and process analytics to improve yield, purity, and consistency. This role is critical in biotech and pharmaceutical industries to ensure safe and effective drug production for clinical and commercial use.

What are typical daily responsibilities for someone in Downstream Process Development?

Professionals in Downstream Process Development are typically responsible for designing, optimizing, and scaling up purification processes for biopharmaceutical products. Their day-to-day work may involve conducting laboratory experiments, analyzing data, troubleshooting technical issues, and documenting process changes in accordance with regulatory standards. They also frequently collaborate with upstream processing, analytical, and quality teams to ensure seamless transfer and integration of processes. The role often includes participating in project meetings, contributing to process validation efforts, and supporting technology transfer to manufacturing teams, making it both technically challenging and collaborative.

What are popular job titles related to Downstream Process Development jobs in Massachusetts? For Downstream Process Development jobs in Massachusetts, the most frequently searched job titles are:
What job categories do people searching Downstream Process Development jobs in Massachusetts look for? The top searched job categories for Downstream Process Development jobs in Massachusetts are:
What cities in Massachusetts are hiring for Downstream Process Development jobs? Cities in Massachusetts with the most Downstream Process Development job openings:
Downstream Process Development jobs near you
Infographic showing various Downstream Process Development job openings in Massachusetts as of June 2026, with employment types broken down into 83% Full Time, 15% Part Time, and 2% Contract. Highlights an 85% Physical, 4% Hybrid, and 11% Remote job distribution, with an average salary of $76,515 per year, or $36.8 per hour.
Development Engineer II

Development Engineer II

Integrated Resources INC

Lexington, MA

Contractor

Posted 22 days ago

Job description

Company Description

A Few Words About Us Integrated Resources, Inc is a premier staffing firm recognized as one of the tri-states most well-respected professional specialty firms. IRI has built its reputation on excellent service and integrity since its inception in 1996. Our mission centers on delivering only the best quality talent, the first time and every time. We provide quality resources in four specialty areas: Information Technology (IT), Clinical Research, Rehabilitation Therapy and Nursing.

Job Description

Client: Direct Client

Location: Lexington, MA

Job Title: Development Engineer II

Duration: 1 Year + (Possible Extension)


Qualifications:

As a member of the Manufacturing Science & Technology group in Process Development department, this individual will join a group of process scientist and engineers to support downstream processes of commercial productions and late stage clinical process development and productions. The scope of work will include designing studies under instruction, executing experiments and data analysis to support GMP investigations and manufacturing change controls and to reduce reoccurring deviations. The focus of the work will be downstream unit operations such as column chromatography, harvest clarification, TFF and normal flow filtration. This individual will interact with other PD groups and other departments including manufacturing, PTS, QC, QA and Engineering etc. 


Job Functions 

Design studies under management instruction, execute experiments and perform data analysis, and to continuously improve the process and to reduce reoccurring deviations 

Under supervision, support root cause analysis during GMP investigations, and provide technical assessments for deviations and Change Controls 

Write study proposals, research and development reports, and various technical memos 

Evaluate new technologies under instructions to improve the commercial production process 

Provide technical and scientific training to manufacturing supervisors and technicians 




Qualifications

Education and Experience Requirements 


BS degree in Chemical Engineering, Biochemistry/Protein Chemistry or related disciplines


3 years of relevant experience in a biotechnology/pharmaceutical environment is required. 


Experience with column chromatography and TFF is required. 


Knowledge of the quality systems and other regulatory requirements necessary to manufacture biologics in a cGMP environment is preferred.

Additional Information

KThanks!!!


Warm Regards,

Amrit Singh

Clinical Recruiter

Integrated Resources, Inc.

IT REHAB CLINICAL NURSING

Tel: (732) 429 1634 (Direct)

Ext: (732) 549 2030 x (212) 

Fax: (732) 549 5549

http://www.irionline.com

Inc. 5000 - 2007, 2008, 2009, 2010, 2011, 2012, 2013 & 2014 (8th Year)

Certified MBE I GSA - Schedule 66 I GSA - Schedule 621I I GSA - Schedule 70

https://www.linkedin.com/company/46970?trk=prof-exp-company-name




Integrated Resources logo

About Integrated Resources

Sourced by ZipRecruiter

Integrated Resources Inc (IRI), based in Edison, NJ, US, is an esteemed player in the staffing solutions industry with a credible presence on their official website irionline.com. Notably, IRI provides a range of professional staffing services including contract, contract-to-hire, and direct hire solutions to a wide spectrum of industries such as healthcare, life sciences, manufacturing, financial, insurance, and others. Since its inception, IRI has been committed to delivering top-talent and optimum solutions to meet its clients' diverse needs.

Industry

Recruiting and staffing services

Company size

51 - 200 Employees

Headquarters location

Edison, NJ, US

Year founded

1996

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