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Downstream Process Development Jobs in Illinois (NOW HIRING)

Brindley Engineering

Lead Process Engineer

Lisle, IL · On-site

$140K - $185K/yr

... downstream engineering disciplines, develop equipment specifications, compile scope of work ... Knowledge of P&ID development, heat and material balances, hydraulic and equipment sizing ...

Brindley Engineering

Lead Process Engineer

Lisle, IL · On-site

$140K - $185K/yr

... downstream engineering disciplines, develop equipment specifications, compile scope of work ... Knowledge of P&ID development, heat and material balances, hydraulic and equipment sizing ...

Brindley Engineering

Lead Process Engineer

Lisle, IL · On-site

$140K - $185K/yr

... downstream engineering disciplines, develop equipment specifications, compile scope of work ... Knowledge of P&ID development, heat and material balances, hydraulic and equipment sizing ...

DocuSign

GTM Business Process Manager

Chicago, IL · Hybrid

In this role, you are responsible for the development, management, and improvement of both new and ... Manage stakeholders and user groups to determine downstream impacts of process, or system changes

Advanced Drainage Systems

Downstream Technician

Lacon, IL · On-site

$18.50 - $19.50/hr

ADS offers competitive compensation, professional development opportunities, and competitive ... We value diverse perspectives, recognizing that they drive better ideas, processes, and performance.

Advanced Drainage Systems

Downstream Technician

Lacon, IL · On-site

$18.50 - $19.50/hr

ADS offers competitive compensation, professional development opportunities, and competitive ... We value diverse perspectives, recognizing that they drive better ideas, processes, and performance.

Numerator

Technical Product Manager

Chicago, IL · Remote

$88K - $121K/yr

... downstream processes to utilize. The role is a mix of strategic and tactical - looking for new ... This role will work with many other back-end development teams, including Deep Learning and Mobile ...

Numerator

Technical Product Manager

Chicago, IL · Remote

$88K - $121K/yr

... downstream processes to utilize. The role is a mix of strategic and tactical - looking for new ... This role will work with many other back-end development teams, including Deep Learning and Mobile ...

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$18

$32

$47

How much do downstream process development jobs pay per hour?

As of Aug 19, 2026, the average hourly pay for downstream process development in Illinois is $32.64, according to ZipRecruiter salary data. Most workers in this role earn between $26.78 and $40.05 per hour, depending on experience, location, and employer.

What is downstream process development?

A Downstream Process Development job involves optimizing and scaling purification processes for biologics, such as proteins, antibodies, or gene therapies. Scientists and engineers in this role develop efficient methods for isolation, purification, and formulation of therapeutic products while ensuring quality and regulatory compliance. Key activities include chromatography, filtration, and process analytics to improve yield, purity, and consistency. This role is critical in biotech and pharmaceutical industries to ensure safe and effective drug production for clinical and commercial use.

What does someone in downstream process development do?

Professionals in Downstream Process Development are typically responsible for designing, optimizing, and scaling up purification processes for biopharmaceutical products. Their day-to-day work may involve conducting laboratory experiments, analyzing data, troubleshooting technical issues, and documenting process changes in accordance with regulatory standards. They also frequently collaborate with upstream processing, analytical, and quality teams to ensure seamless transfer and integration of processes. The role often includes participating in project meetings, contributing to process validation efforts, and supporting technology transfer to manufacturing teams, making it both technically challenging and collaborative.

What are the key skills and qualifications needed for downstream process development?

To excel in Downstream Process Development, you generally need a strong background in biochemistry, chemical engineering, or a related life sciences field, often with experience in bioprocessing or purification technologies. Familiarity with chromatography systems, filtration equipment, process analytical technology (PAT), and relevant software such as DeltaV or Unicorn is frequently required, along with knowledge of GMP and regulatory standards. Excellent problem-solving, project management, and cross-functional communication skills help professionals succeed in dynamic team environments. These competencies are crucial for developing efficient, scalable purification processes that ensure high product quality and support organizational goals.

What are the most commonly searched types of Downstream Process Development jobs in Illinois?

The most popular types of Downstream Process Development jobs in Illinois are:

What are popular job titles related to Downstream Process Development jobs in Illinois?

For Downstream Process Development jobs in Illinois, the most frequently searched job titles are:

What job categories do people searching Downstream Process Development jobs in Illinois look for?

The top searched job categories for Downstream Process Development jobs in Illinois are:

Downstream Process Development jobs near you
Infographic showing various Downstream Process Development job openings in Illinois as of August 2026, with employment types broken down into 1% As Needed, 86% Full Time, 11% Part Time, and 2% Contract. Highlights an 89% Physical, 3% Hybrid, and 8% Remote job distribution, with an average salary of $67,890 per year, or $32.6 per hour.

Lead Process Engineer

Brindley Engineering

Lisle, IL • On-site

$140K - $185K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted yesterday

Job description

Job Description:
Detail-oriented, reliable, creative team player to lead in process design for new and existing facilities.  Analyze, calculate, and design new or revamped process equipment in refinery, chemical, and other industrial applications.
 
Job Duties/Responsibilities:
Lead field and technical evaluations of existing process units
Provide technical direction for refinery and chemical process units and licensed technologies
Direct and perform calculations, develop PFDs and P&IDs, provide design documentation for downstream engineering disciplines, develop equipment specifications, compile scope of work packages for construction
Lead Client and Contractor interface, attend meetings, and provide written reports
Provide technical support for field execution, including outage/turnaround projects
Assist in constructability planning, proposal, and estimate development
 
Minimum Qualifications:
Education: Bachelor of Science in Chemical Engineering
Experience:Min Yr = 10+ 
Licensure: P.E. Preferred
Technical Skills: Knowledge of P&ID development, heat and material balances, hydraulic and equipment sizing calculations, relief device sizing, API standards, and ASME codes required
Strong technical knowledge of refinery and chemical plant unit operations and/or licensed technologies
Management: Experience mentoring and leading teams required
Other Skills: Strong organizational, written and verbal communication skills
 
Professional Development Opportunities:
Advance technical knowledge of refinery and chemical process unit operations and licensed technologies
Advanced knowledge of applicable codes and standards, involvement in AIChE or similar local/national chapters and code committees (API, ASME etc) 
Growth in leading technical teams as subject matter expert or lead engineer
Advance skills in multi-discipline technical and managerial environment
 
Individual field assignments typically each have their own unique requirements.  Prior to deployment on any field assignment, you must be able to meet all client-specific site requirements.  Should you be unable or unwilling to meet assignment-specific requirements, your continued employment would then be subject to the availability of other assignments whose requirements can be met.  These unique requirements may include:
 
You must possess physical mobility (on the ground and at heights).
You may be required to pick up, lift, carry, and move up to 50 lbs.
You may be required to work at heights, climb ladders and stairways, and may occasionally work off platforms/scaffolding/ladders using the appropriate and required fall protection.  
You must be able to work in all weather conditions (including heat, rain, cold, and wind) while wearing the appropriate PPE. This may include but not be limited to a hard hat, safety glasses/goggles, ear plugs, masks/respirators, hi-vis safety vests, leather gloves, and leather, steel-toed work boots.  
You may be required to position yourself to work in confined spaces
You may be required to adhere to a client's random drug testing program prior to entering their site.
You may be required to meet a client's facial hair safety policy prior to entering their site.
 
Pay Range: $140,000 - $185,000 annually
 
The above pay range represents a general guideline; however, Brindley considers several factors when determining base salary that are unique to each candidate, including but not limited to the candidate's depth of experience, skill set, certifications, specific work location, and current market conditions. Employees may be eligible for discretionary bonus and/or other applicable incentive compensation plans in addition to base pay to reward individual contributions and allow employees to share in company results. 
 
In addition, BE provides a comprehensive benefits package for eligible employees, including health, dental, and vision insurance, life and disability insurance, a 401(k) savings plan with employer matching, company-paid holidays, paid parental leave, compensatory time off, and paid time off (PTO). Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment.
 
Brindley Engineering is an Equal Opportunity Employer and committed to hiring and retaining a diverse workforce. Employment decisions are made without regard to race, color, religion, creed, sex, sexual orientation, gender identity, marital status, national origin, age, veteran status, disability, or any other protected characteristic as outlined by federal, state, or local laws.
 
BE participates in E-Verify. For additional information regarding E-Verify, please go to www.e-verify.gov.
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