ZipRecruiter

Log In

1

Downstream Process Development Jobs in Illinois (NOW HIRING)

Clarke

Senior Microbiologist

Saint Charles, IL · On-site

$95K - $120K/yr

... downstream process optimization, as well as the isolation or purification of the product of ... development and training opportunities, LinkedIn Learning subscriptions, paid parental leave ...

Clarke

Senior Microbiologist

Lombard, IL · On-site

... downstream process optimization, as well as the isolation or purification of the product of ... development and training opportunities, LinkedIn Learning subscriptions, paid parental leave ...

Clarke

Senior Microbiologist

Saint Charles, IL · On-site

$95K - $120K/yr

... downstream process optimization, as well as the isolation or purification of the product of ... development and training opportunities, LinkedIn Learning subscriptions, paid parental leave ...

Brindley Engineering

Staff Process Engineer

Lisle, IL · On-site

$110K - $150K/yr

... downstream engineering disciplines, develop equipment specifications, compile scope of work ... Knowledge of P&ID development, heat and material balances, hydraulic and equipment sizing ...

Marsh McLennan

Senior Enterprise Architect

Cary, IL · On-site

... downstream process dependencies across core servicing, transaction, and operational workflows ... Manage the development of supporting application components, interface/design of systems as well as ...

Marsh McLennan

Senior Enterprise Architect

Chicago, IL · On-site

... downstream process dependencies across core servicing, transaction, and operational workflows ... Manage the development of supporting application components, interface/design of systems as well as ...

Marsh McLennan

Senior Enterprise Architect

Virginia, IL · On-site

... downstream process dependencies across core servicing, transaction, and operational workflows ... Manage the development of supporting application components, interface/design of systems as well as ...

Brindley Engineering

Lead Process Engineer

Lisle, IL · On-site

$140K - $185K/yr

... downstream engineering disciplines, develop equipment specifications, compile scope of work ... Knowledge of P&ID development, heat and material balances, hydraulic and equipment sizing ...

Marsh McLennan

Senior Enterprise Architect

Darien, IL · On-site

... downstream process dependencies across core servicing, transaction, and operational workflows ... Manage the development of supporting application components, interface/design of systems as well as ...

Morningstar, Inc.

Global Process Owner

Chicago, IL · On-site

$156K - $170K/yr

Collaborate with other functions, upstream and downstream, to align and leverage cross-process ... and Macro development. **Will accept any suitable combination of education, training, and ...

Brindley Engineering

Lead Process Engineer

Lisle, IL · On-site

$140K - $185K/yr

... downstream engineering disciplines, develop equipment specifications, compile scope of work ... Knowledge of P&ID development, heat and material balances, hydraulic and equipment sizing ...

Morningstar, Inc.

Global Process Owner

Chicago, IL · On-site

$156K - $170K/yr

Collaborate with other functions, upstream and downstream, to align and leverage cross-process ... and Macro development. **Will accept any suitable combination of education, training, and ...

Brindley Engineering

Lead Process Engineer

Lisle, IL · On-site

$140K - $185K/yr

... downstream engineering disciplines, develop equipment specifications, compile scope of work ... Knowledge of P&ID development, heat and material balances, hydraulic and equipment sizing ...

previous page

Showing results 41-60

All JobsDownstream Process Development JobsDownstream Process Development Jobs in Illinois

Downstream Process Development information

See Illinois salary details

$18

$32

$47

How much do downstream process development jobs pay per hour?

As of Sep 10, 2026, the average hourly pay for downstream process development in Illinois is $32.64, according to ZipRecruiter salary data. Most workers in this role earn between $26.78 and $40.05 per hour, depending on experience, location, and employer.

What is downstream process development?

A Downstream Process Development job involves optimizing and scaling purification processes for biologics, such as proteins, antibodies, or gene therapies. Scientists and engineers in this role develop efficient methods for isolation, purification, and formulation of therapeutic products while ensuring quality and regulatory compliance. Key activities include chromatography, filtration, and process analytics to improve yield, purity, and consistency. This role is critical in biotech and pharmaceutical industries to ensure safe and effective drug production for clinical and commercial use.

What does someone in downstream process development do?

Professionals in Downstream Process Development are typically responsible for designing, optimizing, and scaling up purification processes for biopharmaceutical products. Their day-to-day work may involve conducting laboratory experiments, analyzing data, troubleshooting technical issues, and documenting process changes in accordance with regulatory standards. They also frequently collaborate with upstream processing, analytical, and quality teams to ensure seamless transfer and integration of processes. The role often includes participating in project meetings, contributing to process validation efforts, and supporting technology transfer to manufacturing teams, making it both technically challenging and collaborative.

What are the key skills and qualifications needed for downstream process development?

To excel in Downstream Process Development, you generally need a strong background in biochemistry, chemical engineering, or a related life sciences field, often with experience in bioprocessing or purification technologies. Familiarity with chromatography systems, filtration equipment, process analytical technology (PAT), and relevant software such as DeltaV or Unicorn is frequently required, along with knowledge of GMP and regulatory standards. Excellent problem-solving, project management, and cross-functional communication skills help professionals succeed in dynamic team environments. These competencies are crucial for developing efficient, scalable purification processes that ensure high product quality and support organizational goals.

What are the most commonly searched types of Downstream Process Development jobs in Illinois?

The most popular types of Downstream Process Development jobs in Illinois are:

What job categories do people searching Downstream Process Development jobs in Illinois look for?

The top searched job categories for Downstream Process Development jobs in Illinois are:

Downstream Process Development jobs near you
Infographic showing various Downstream Process Development job openings in Illinois as of September 2026, with employment types broken down into 1% Internship, 1% As Needed, 74% Full Time, 19% Part Time, 2% Contract, and 3% Nights. Highlights an 86% Physical, 3% Hybrid, and 11% Remote job distribution, with an average salary of $67,890 per year, or $32.6 per hour.

Senior Microbiologist

Saint Charles, IL • On-site

Clarke
See more jobs at Clarkeexternal

$95K - $120K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 15 days ago

Job description

Senior Microbiologist
Are you a passionate scientist who thrives on solving complex biological challenges and turning research into real-world solutions? We are seeking a Senior Microbiologist to play a key role in advancing innovative products, supporting scientific research, and driving microbiological excellence across our organization.
This is an exciting opportunity for a highly motivated professional who is committed to scientific integrity, continuous improvement, and making a measurable impact.
Key Responsibilities
  • Lead daily microbiology lab operations, ensuring efficient workflow and compliance with quality and safety standards.
  • Serve as the SME for microbial active ingredients and Bacillus-based technologies, providing scientific and technical guidance.
  • Lead biological active ingredient programs from evaluation through commercialization, including scale-up and regulatory support.
  • Develop and optimize microbial cultivation and fermentation processes to improve yield, scalability, and readiness for manufacturing.
  • Maintain microbial culture collections and troubleshoot microbiological challenges through root cause analysis.
  • Collaborate with Quality, Manufacturing, Regulatory, and Product Development teams to support innovation and commercialization.
  • Develop microbiological testing methods, validation protocols, and quality control systems to support compliance and product integrity.
  • Provide project leadership, manage priorities and resources, and communicate progress to leadership.
  • Mentor microbiologists and lab personnel through coaching, training, and technical guidance.
  • Conduct research, literature reviews, and patent searches to identify emerging technologies and actionable recommendations.
  • Prepare and present technical documentation, reports, protocols, and research findings.
  • Ensure compliance with ISO, GLP, and regulatory requirements while promoting safety, innovation, and continuous improvement.

Hours: Monday - Friday, 8am - 5pm
Location: St Charles, IL
Candidates should be located in reasonable proximity to St. Charles, IL. Relocation assistance will not be provided.
Top Qualifications
  • M.Sc. in Microbiology, biotechnology or related field with 5+ years of relevant experience, OR B.Sc. with 8+ years of relevant experience in a reputable industry. PhD is strongly preferred.
  • Demonstrate proficiency in aseptic techniques, including hands-on experience with tasks such as cell counting, streak plating, analyzing bacterial media characteristics & interpreting optical density readings.
  • Possess hands-on expertise in bioreactor operations, encompassing a comprehensive understanding of various bioreactor components, proficiency in bio command software utilization, and a preference for experience in downstream process optimization, as well as the isolation or purification of the product of interest.
  • Ability to work independently, think critically, and adapt based on observations and learning.
  • Computer proficiency and aptitude related to data collection and interpretation, report writing and presentation.
  • Ability to communicate effectively in English in both verbal and written form.
  • Ability to travel for short periods and at last-minute notice (up to 20%).

This is an exempt salary position and the hiring range for this position is expected to be $95,000-$120,000. This range reflects an anticipated range for this position. The salary range offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, and certifications or other professional licenses held.
BENEFITS
We offer an outstanding compensation and benefits package including medical, dental, vision, life, disability, 401k (Roth and traditional) with a generous match, tuition reimbursement and career development and training opportunities, LinkedIn Learning subscriptions, paid parental leave program, electric vehicle incentives, paid volunteer time, generous PTO, paid holidays, paid winter break between Christmas and New Years, and discretionary bonus.
ABOUT CLARKE
Clarke is a global leader in environmentally responsible mosquito control. You'll join a team that cares about people, the planet, and meaningful work.
ARE YOU READY?
If you are excited about what you've read and feel that you are right for this role, please submit your resume and relevant information.
Be sure to check out our website ( ) to learn more about how Clarke is helping to make the world more livable, safe & comfortable.
Clarke is proud to be an equal opportunity employer and a drug free workplace.

Apply