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Downstream Process Development Jobs in Illinois (NOW HIRING)

... downstream engineering disciplines, develop equipment specifications, compile scope of work ... Knowledge of P&ID development, heat and material balances, hydraulic and equipment sizing ...

Staff Process Engineer

Lisle, IL · On-site

$110K - $150K/yr

... downstream engineering disciplines, develop equipment specifications, compile scope of work ... Knowledge of P&ID development, heat and material balances, hydraulic and equipment sizing ...

... downstream engineering disciplines, develop equipment specifications, compile scope of work ... Knowledge of P&ID development, heat and material balances, hydraulic and equipment sizing ...

Staff Process Engineer

Lisle, IL · On-site

$110K - $150K/yr

... downstream engineering disciplines, develop equipment specifications, compile scope of work ... Knowledge of P&ID development, heat and material balances, hydraulic and equipment sizing ...

Lead Process Engineer

Lisle, IL · On-site

$140K - $185K/yr

... downstream engineering disciplines, develop equipment specifications, compile scope of work ... Knowledge of P&ID development, heat and material balances, hydraulic and equipment sizing ...

Global Process Owner

Chicago, IL · On-site

$156K - $170K/yr

Collaborate with other functions, upstream and downstream, to align and leverage cross-process ... and Macro development. **Will accept any suitable combination of education, training, and ...

... downstream engineering disciplines, develop equipment specifications, compile scope of work ... Knowledge of P&ID development, heat and material balances, hydraulic and equipment sizing ...

... downstream engineering disciplines, develop equipment specifications, compile scope of work ... Knowledge of P&ID development, heat and material balances, hydraulic and equipment sizing ...

Lead Process Engineer

Lisle, IL · On-site

$140K - $185K/yr

... downstream engineering disciplines, develop equipment specifications, compile scope of work ... Knowledge of P&ID development, heat and material balances, hydraulic and equipment sizing ...

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Downstream Process Development information

See Illinois salary details

$18

$32

$47

How much do downstream process development jobs pay per hour?

As of Jun 28, 2026, the average hourly pay for downstream process development in Illinois is $32.64, according to ZipRecruiter salary data. Most workers in this role earn between $26.78 and $40.05 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in the Downstream Process Development position, and why are they important?

To excel in Downstream Process Development, you generally need a strong background in biochemistry, chemical engineering, or a related life sciences field, often with experience in bioprocessing or purification technologies. Familiarity with chromatography systems, filtration equipment, process analytical technology (PAT), and relevant software such as DeltaV or Unicorn is frequently required, along with knowledge of GMP and regulatory standards. Excellent problem-solving, project management, and cross-functional communication skills help professionals succeed in dynamic team environments. These competencies are crucial for developing efficient, scalable purification processes that ensure high product quality and support organizational goals.

What is a Downstream Process Development job?

A Downstream Process Development job involves optimizing and scaling purification processes for biologics, such as proteins, antibodies, or gene therapies. Scientists and engineers in this role develop efficient methods for isolation, purification, and formulation of therapeutic products while ensuring quality and regulatory compliance. Key activities include chromatography, filtration, and process analytics to improve yield, purity, and consistency. This role is critical in biotech and pharmaceutical industries to ensure safe and effective drug production for clinical and commercial use.

What are typical daily responsibilities for someone in Downstream Process Development?

Professionals in Downstream Process Development are typically responsible for designing, optimizing, and scaling up purification processes for biopharmaceutical products. Their day-to-day work may involve conducting laboratory experiments, analyzing data, troubleshooting technical issues, and documenting process changes in accordance with regulatory standards. They also frequently collaborate with upstream processing, analytical, and quality teams to ensure seamless transfer and integration of processes. The role often includes participating in project meetings, contributing to process validation efforts, and supporting technology transfer to manufacturing teams, making it both technically challenging and collaborative.

What are the most commonly searched types of Downstream Process Development jobs in Illinois? The most popular types of Downstream Process Development jobs in Illinois are:
What are popular job titles related to Downstream Process Development jobs in Illinois? For Downstream Process Development jobs in Illinois, the most frequently searched job titles are:
What job categories do people searching Downstream Process Development jobs in Illinois look for? The top searched job categories for Downstream Process Development jobs in Illinois are:
Infographic showing various Downstream Process Development job openings in Illinois as of June 2026, with employment types broken down into 83% Full Time, 15% Part Time, and 2% Contract. Highlights an 84% Physical, 5% Hybrid, and 11% Remote job distribution, with an average salary of $67,890 per year, or $32.6 per hour.
Associate Process Engineer

Associate Process Engineer

Brindley Engineering

Lisle, IL • On-site

$90K - $130K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 9 days ago


Key responsibilities

  • Conduct field and technical evaluations of existing process units.

  • Perform calculations, develop PFDs and P&IDs, provide design documentation for downstream engineering disciplines, develop equipment specifications, and compile scope of work packages for construction.

  • Interface with client and construction, attend meetings, and provide written reports.


Job description


Detail-oriented, reliable, creative team player to lead/assist in process design for new and existing facilities. Analyze, calculate, and design new or revamped process equipment in refinery, chemical, and other industrial applications.
Job Duties/Responsibilities:
• Conduct field and technical evaluations of existing process units
• Perform calculations, develop PFDs and P&IDs, provide design documentation for downstream engineering disciplines, develop equipment specifications, compile scope of work packages for construction
• Interface with Client and Construction, attend meetings, and provide written reports
• Provide technical support for field execution, including outage/turnaround projects
Minimum Qualifications:
• Education: Bachelor of Science in Chemical Engineering
• Experience: Min Yr = 3+
• Licensure: E.I.T. Preferred, PE license a plus
• Technical Skills: Knowledge of P&ID development, heat and material balances, hydraulic and equipment sizing calculations, relief device sizing, API standards, and ASME codes required. Knowledge of process simulation software (e.g., Aspen Plus, HYSYS) preferred
• Management: Experience in coordinating across multiple disciplines required
• Other Skills: Strong organizational, written, and verbal communication skills
Professional Development Opportunities:
• Development of experience leading small teams of process engineers in a multi-disciplinary engineering environment
• Opportunity to begin mentoring entry-level and graduate engineers and advance leadership skillset
• Autonomy in field evaluation assignments
• Advanced experience in process modeling and calculations
• Obtain industry and skill-specific certifications
Individual field assignments typically have their own unique requirements. Prior to deployment on any field assignment, you must be able to meet all client-specific site requirements. Should you be unable or unwilling to meet assignment-specific requirements, your continued employment would then be subject to the availability of other assignments whose requirements can be met. These unique requirements may include:
• You must possess physical mobility (on the ground and at heights).
• You may be required to pick up, lift, carry, and move up to 50 lbs.
• You may be required to work at heights, climb ladders and stairways, and may occasionally work off platforms/scaffolding/ladders using the appropriate and required fall protection.
• You must be able to work in all weather conditions (including heat, rain, cold, and wind) while wearing the appropriate PPE. This may include, but not be limited to, a hard hat, safety glasses/goggles, earplugs, masks/respirators, hi-vis safety vests, leather gloves, and leather, steel-toed work boots.
• You may be required to position yourself to work in confined spaces
• You may be required to adhere to a client's random drug testing program prior to entering their site.
• You may be required to meet a client's facial hair safety policy prior to entering their site.
Pay Range: $90,000 - $130,000 annually
The above pay range represents a general guideline; however, Brindley considers several factors when determining base salary that are unique to each candidate, including but not limited to the candidate's depth of experience, skill set, certifications, specific work location, and current market conditions. Employees may be eligible for a discretionary bonus and/or other applicable incentive compensation plans in addition to base pay to reward individual contributions and allow employees to share in company results.
In addition, BE provides a comprehensive benefits package for eligible employees, including health, dental, and vision insurance, life and disability insurance, 401(k) savings plan with employer matching, company-paid holidays, paid parental leave, compensatory time off, and paid time off (PTO). Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment.
Brindley Engineering is an Equal Opportunity Employer and is committed to hiring and retaining a diverse workforce. Employment decisions are made without regard to race, color, religion, creed, sex, sexual orientation, gender identity, marital status, national origin, age, veteran status, disability, or any other protected characteristic as outlined by federal, state, or local laws.
BE participates in E-Verify. For additional information regarding E-Verify, please go to www.e-verify.gov.