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Downstream Manufacturing Supervisor Jobs (NOW HIRING)

## Manufacturing Supervisor - Aseptic Upstream BioprocessingApplylocations: Elwood, KStime type: Full ... partnering with downstream and fill finish and ensuring adherence to production schedules.

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Downstream Manufacturing Supervisor information

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$30.5K

$97.6K

$153.5K

How much do downstream manufacturing supervisor jobs pay per year?

As of Sep 9, 2026, the average yearly pay for downstream manufacturing supervisor in the United States is $97,556.00, according to ZipRecruiter salary data. Most workers in this role earn between $78,000.00 and $120,500.00 per year, depending on experience, location, and employer.

What does a downstream manufacturing supervisor do?

A Downstream Manufacturing Supervisor oversees the purification and processing steps in the production of biopharmaceutical products after the initial cell culture or fermentation phase. They manage teams responsible for filtration, chromatography, and formulation to ensure products meet quality and regulatory standards. The supervisor coordinates daily operations, troubleshoots process issues, and ensures compliance with Good Manufacturing Practices (GMP). They also play a key role in training staff, optimizing workflows, and maintaining safety protocols.

What are the key skills and qualifications needed to thrive as a downstream manufacturing supervisor, and why are they important?

To thrive as a Downstream Manufacturing Supervisor, you need a strong background in bioprocessing, GMP regulations, and supervisory experience, usually backed by a degree in life sciences or engineering. Familiarity with downstream processing equipment, process control systems, and quality management software is essential. Leadership, problem-solving, and effective communication are critical soft skills for managing teams and ensuring compliance. These skills ensure efficient production, product quality, and regulatory adherence in a fast-paced manufacturing environment.

What are some common challenges faced by downstream manufacturing supervisors, and how can they be addressed?

Downstream Manufacturing Supervisors often encounter challenges such as maintaining process consistency, ensuring compliance with strict quality standards, and managing tight production schedules. Addressing these challenges requires strong organizational skills, effective communication with both upstream and downstream teams, and a proactive approach to troubleshooting equipment or process deviations. Building a culture of continuous improvement and fostering collaboration within the team are also key to overcoming obstacles and meeting production goals efficiently.

What is the difference between Downstream Manufacturing Supervisor vs Process Technician?

AspectDownstream Manufacturing SupervisorProcess Technician
CredentialsTypically requires a bachelor's degree in engineering or related fieldOften requires a diploma or associate degree in process technology or similar
Work EnvironmentSupervises production lines in manufacturing plants, overseeing teamsOperates and monitors equipment, performs troubleshooting on the production floor
Industry UsageCommonly used in pharmaceutical, chemical, and biotech manufacturingWidely used in similar industries for equipment operation and process control

The Downstream Manufacturing Supervisor oversees production teams and ensures manufacturing processes run smoothly, while the Process Technician focuses on operating and maintaining equipment. Both roles are essential in manufacturing settings, but the supervisor has a broader leadership responsibility, whereas the technician is more hands-on with daily operations.

What cities are hiring for Downstream Manufacturing Supervisor jobs?

Cities with the most Downstream Manufacturing Supervisor job openings:

What states have the most Downstream Manufacturing Supervisor jobs?

States with the most job openings for Downstream Manufacturing Supervisor jobs include:

What are popular job titles related to Downstream Manufacturing Supervisor jobs?

For Downstream Manufacturing Supervisor jobs, the most frequently searched job titles are:

Infographic showing various Downstream Manufacturing Supervisor job openings in the United States as of June 2026, with employment types broken down into 92% Full Time, 5% Part Time, and 3% Nights. Highlights an 86% Physical, 3% Hybrid, and 11% Remote job distribution, with an average salary of $97,556 per year, or $46.9 per hour.

PRODUCTION SUPERVISOR

Neenah, WI

United Plastic Fabricating Inc
Plastics Product Manufacturing • 201 - 500 employees

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 19 days ago


United Plastic Fabricating rating

7.5

Company rating: 7.5 out of 10

Based on 5 frontline employees who took The Breakroom Quiz

31st of 85 rated plastic manufacturers


Job description

Description

Shift: Wednesday, Thursday, Friday, Saturday 10 hour days


United Plastic Fabricating (UPF) is looking for an experienced Production Supervisor / Manufacturing  Supervisor to lead our weekend manufacturing team.  


We're looking for a hands-on leader who enjoys developing people, solving production problems, and improving how work gets done. This isn't a role where success means simply keeping the shift running.  Our strongest supervisors understand the entire production environment (people, materials, equipment, quality, safety, production flow, and changing priorities) and can see problems developing before they disrupt the operation.  


What You'll Own  

  • Lead day-to-day manufacturing and production operations for your shift.  
  • Build a strong, accountable team focused on safety, quality, productivity, and delivery.  
  • Maintain a visible, hands-on presence on the production floor.  
  • Manage staffing, workflow, materials, equipment, and changing production priorities to maintain effective production flow and cadence.  
  • Identify bottlenecks, constraints, quality concerns, and production interruptions before they become larger problems.  
  • Understand how upstream and downstream manufacturing processes affect one another and make decisions with the entire production system in mind.  
  • Troubleshoot manufacturing issues and partner with Engineering, Maintenance, Quality, Materials, and Operations to solve root causes.  
  • Coach and develop employees while maintaining clear expectations and accountability.  
  • Support lean manufacturing, continuous improvement, process improvement, and operational excellence.  
  • Identify opportunities to reduce waste, rework, delays, and recurring production problems.  


What Success Looks Like  

A successful Production Supervisor doesn't simply react quickly when something goes wrong. They create an operation where fewer things go wrong in the first place. 



Requirements

 What You Bring  


  • Previous experience as a Production Supervisor, Manufacturing Supervisor, Operations Supervisor, Shift Supervisor, Production Lead, Manufacturing Team Lead, or similar manufacturing leadership role.  
  • Experience leading teams in a manufacturing, fabrication, production, or assembly environment.  
  • Strong analytical, troubleshooting, and root-cause problem-solving skills.  
  • Ability to understand manufacturing systems, production flow, bottlenecks, constraints, and downstream impacts.  
  • Experience managing staffing, workflow, production priorities, and changing operating conditions.  
  • Strong communication, coaching, and people leadership skills.  
  • Mechanical or technical aptitude and comfort working in a hands-on manufacturing environment.  
  • Ability to use production information, operating data, and computer systems to make decisions.  
  • Strong ownership, judgment, urgency, and follow-through.  
  • A genuine interest in continuous improvement and helping both people and processes perform better.  

Experience in high-mix/low-volume manufacturing, flow manufacturing, assembly operations, custom manufacturing, lean manufacturing, production line balancing, or technical fabrication environments is especially valuable.  


A bachelor's degree in engineering, Manufacturing, Operations, or a related discipline is desired, but strong manufacturing leadership and systems knowledge gained through experience are equally important.  


 What We Offer  

  • 4-Day Work Week  
  • Paid Time Off  
  • Profit Sharing Program - potential to earn an extra paycheck per month  
  • Health, Dental, Vision and Life Insurance  
  • Paid Parental Leave  
  • Short-Term and Long-Term Disability  
  • Paid Holidays  
  • 401(k) with Match  
  • Student Loan Assistance Program  
  • Tuition Assistance 

UPF is an Equal Opportunity Employer and does not discriminate on the basis of race, ancestry, national origin, color, religion, gender, age, marital status, sexual orientation, disability or veteran status.


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