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Dmpk Scientist Jobs (NOW HIRING)

Merck & Co., Inc.

Principal Scientist, DMPK

Boston, MA · On-site

... DMPK, Drug Metabolism, Immunoassays, Immunology, In Vitro Studies, Mentoring Staff, Oncology, Peptides, Pharmaceutical Sciences, Pharmacodynamics, Pharmacokinetics, Pharmacotherapeutics, PKPD ...

Alnylam Pharmaceuticals

Scientist, DMPK

Cambridge, MA

$110K - $165K/yr

... scientists across a broad array of disciplinary expertise areas. This position is onsite and will be primarily located in Cambridge, MA. Key Responsibilities Support DMPK strategy across drug ...

Alnylam Pharmaceuticals, Inc.

Scientist, DMPK

Cambridge, MA · On-site

$110 - $166/hr

... scientists across a broad array of disciplinary expertise areas.This position is onsite and will be primarily located in Cambridge, MA.Key ResponsibilitiesSupport DMPK strategy across drug discovery ...

Alnylam Pharmaceuticals

Scientist, DMPK

Cambridge, MA · On-site

$110K - $165K/yr

... scientists across a broad array of disciplinary expertise areas. This position is onsite and will be primarily located in Cambridge, MA. Key Responsibilities * Support DMPK strategy across drug ...

Pharmaron

Scientist II, Discovery DMPK

Exton, PA · On-site

$55K - $65K/yr

Scientist II, Discovery DMPK Salary Range: $55,000-$65,000 Location: Exton, PA (onsite) About Pharmaron Pharmaron is a global contract research and manufacturing organization (CRO/CDMO) helping ...

WuXi AppTec

Scientist I, DMPK / ADME

Cranbury, NJ · On-site

Overview Associate Scientist I is responsible to conduct routine in vitro ADME assays in compliance ... the DMPK. Responsibilities * Perform routine in vitro ADME assays, laboratory techniques and ...

Pharmaron

Scientist II, Discovery DMPK

Exton, PA · On-site

$55K - $65K/yr

Scientist II, Discovery DMPK Salary Range: $55,000-$65,000 Location: Exton, PA (onsite) About Pharmaron Pharmaron is a global contract research and manufacturing organization (CRO/CDMO) helping ...

Evommune, Inc.

Director, DMPK

Palo Alto, CA · On-site

$190 - $240/hr

Our scientific approach integrates deep immunology expertise with disciplined clinical development ... The Director, DMPK will serve as the DMPK program lead, responsible for establishing and executing ...

WuXi AppTec

Scientist I, DMPK / ADME

Cranbury, NJ · On-site

Associate Scientist I is responsible to conduct routine in vitro ADME assays in compliance with ... DMPK. * Perform routine in vitro ADME assays, laboratory techniques and procedures under ...

WuXi AppTec

Scientist I, DMPK / ADME

Cranbury, NJ · On-site

Associate Scientist I is responsible to conduct routine in vitro ADME assays in compliance with ... DMPK. * Perform routine in vitro ADME assays, laboratory techniques and procedures under ...

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Dmpk Scientist information

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$50.5K

$130.1K

$174K

How much do dmpk scientist jobs pay per year?

As of Sep 5, 2026, the average yearly pay for dmpk scientist in the United States is $130,117.00, according to ZipRecruiter salary data. Most workers in this role earn between $107,500.00 and $173,000.00 per year, depending on experience, location, and employer.

What is a DMPK scientist?

A DMPK (Drug Metabolism and Pharmacokinetics) Scientist studies how drugs are absorbed, distributed, metabolized, and excreted in the body. They design and conduct experiments to evaluate drug safety, efficacy, and optimal dosing. Their work helps predict human responses to drugs and supports regulatory submissions. DMPK Scientists collaborate with chemists, biologists, and clinicians to optimize drug candidates for development.

What are the key skills and qualifications needed to thrive as a DMPK scientist?

A Dmpk Scientist should possess a strong background in pharmacokinetics, pharmacodynamics, bioanalytical chemistry, and typically hold an advanced degree in pharmaceutical sciences or a related field. Familiarity with laboratory automation systems, LC-MS/MS, and relevant software for data analysis (such as WinNonlin or Phoenix) is frequently required. Demonstrating attention to detail, effective communication, and problem-solving skills helps individuals excel in cross-functional team environments. These abilities are vital for advancing drug discovery projects, ensuring accurate data interpretation, and complying with regulatory standards.

What types of projects and collaborations are typical for a DMPK scientist in a pharmaceutical company?

Dmpk Scientists often work on multidisciplinary project teams involved in drug discovery and development, collaborating closely with medicinal chemists, toxicologists, and biologists. Their typical responsibilities include designing and interpreting ADME (absorption, distribution, metabolism, and excretion) studies, evaluating pharmacokinetic profiles, and contributing data for regulatory submissions. Collaboration is key, as Dmpk Scientists must effectively communicate results and recommendations to both technical and non-technical stakeholders. This collaborative environment fosters professional growth and enables direct impact on the progression of therapeutic candidates through the drug development pipeline.

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Dmpk Scientist jobs near you
Infographic showing various Dmpk Scientist job openings in the United States as of August 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution, with an average salary of $130,117 per year, or $62.6 per hour.

Senior Scientist I, DMPK

Scorpion Therapeutics

Madison, WI • On-site

$115 - $140/hr

Other

Posted 6 days ago

Job description

Responsibilities:
  • Develop and implement in vitro and in vivo DMPK strategies to support preclinical development across multiple indications and routes of administration.
  • Manage DMPK activities, including oversight of internal resources and CRO partners, to ensure high-quality, timely data delivery.
  • Design, supervise, and execute preclinical PK studies, including non-compartmental analysis (NCA); interpret data; report; communicate PK/PD insights.
  • Prepare and deliver IND-enabling DMPK packages, ensuring compliance with regulatory expectations and contributing to regulatory submissions.
  • Apply GLP/GCP principles and ensure appropriate documentation for regulated studies.
  • Support GLP toxicokinetic (TK) study design, analysis, and reporting.
  • Oversee metabolite identification in preclinical and clinical samples using high-resolution mass spectrometry (HRMS).
  • Provide scientific leadership, troubleshooting, and cross-functional collaboration.
  • Maintain current knowledge of clinical pharmacology literature and regulatory guidance for oligonucleotide/RNAi therapeutics.
Requirements:
  • PhD in Pharmacometrics, Drug Metabolism, Pharmaceutical Sciences, or related discipline; at least 3 years of industry experience.
  • Deep DMPK expertise; working knowledge of nucleotide/oligonucleotide drug metabolism and distribution (highly desired).
  • Hands-on experience with in vitro ADME assays, in vivo PK studies, DDI evaluations, and Phoenix WinNonlin.
  • LC-MS/MS and HRMS experience, ideally for oligonucleotide therapeutics.
  • Strong background in organic chemistry, biochemistry, and drug biotransformation.
  • Demonstrated drug development experience and understanding of regulatory processes.
  • Excellent communication skills; ability to interpret and present complex scientific data clearly.
Benefits/Pay:
  • Wisconsin pay range: $115,000 USD - $140,000 USD.
  • Competitive salaries and an excellent benefits package.
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