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Dmpk Scientist Jobs (NOW HIRING)

Senior Research Scientist; DMPK in Buffalo, NY Build your future at Curia, where our work has the power to save lives. The Senior Research Scientist, DMPK is an expert in the areas of DMPK and drug ...

Senior Research Scientist; DMPK in Buffalo, NY Build your future at Curia, where our work has the power to save lives. The Senior Research Scientist, DMPK is an expert in the areas of DMPK and drug ...

Senior Scientist I, DMPK

Lexington, MA · Hybrid

$157K - $213K/yr

Description Wave Life Sciences is seeking a highly motivated and detail-oriented Scientist with strong expertise in bioanalytical and Drug Metabolism and Pharmacokinetics (DMPK) sciences to support ...

As part of this expansion, we are seeking a Principal Scientist to take a leading scientific role building our DMPK and bioanalysis capabilities within complex molecular formats. This is a unique ...

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Senior Scientist I, DMPK

Lexington, MA · On-site

$157K - $213K/yr

Description Wave Life Sciences is seeking a highly motivated and detail-oriented Scientist with strong expertise in bioanalytical and Drug Metabolism and Pharmacokinetics (DMPK) sciences to support ...

Senior Scientist I, DMPK

Lexington, MA · On-site

$157 - $213/hr

Description Wave Life Sciences is seeking a highly motivated and detail-oriented Scientist with strong expertise in bioanalytical and Drug Metabolism and Pharmacokinetics (DMPK) sciences to support ...

The ideal candidate will bring deep strategic and scientific expertise in DMPK-BA for one or more biotherapeutic modalities described above, have demonstrated record of people management and ...

Principal Scientist, DMPK

Boston, MA · On-site

$176 - $277/hr

DMPK * Drug Metabolism * Immunoassays * Immunology * In Vitro Studies * Mentoring Staff * Oncology * Peptides * Pharmaceutical Sciences * Pharmacodynamics * Pharmacokinetics * Pharmacotherapeutics

... DMPK, Drug Metabolism, Immunoassays, Immunology, In Vitro Studies, Mentoring Staff, Oncology, Peptides, Pharmaceutical Sciences, Pharmacodynamics, Pharmacokinetics, Pharmacotherapeutics, PKPD ...

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Dmpk Scientist information

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$50.5K

$130.1K

$174K

How much do dmpk scientist jobs pay per year?

As of Sep 5, 2026, the average yearly pay for dmpk scientist in the United States is $130,117.00, according to ZipRecruiter salary data. Most workers in this role earn between $107,500.00 and $173,000.00 per year, depending on experience, location, and employer.

What is a DMPK scientist?

A DMPK (Drug Metabolism and Pharmacokinetics) Scientist studies how drugs are absorbed, distributed, metabolized, and excreted in the body. They design and conduct experiments to evaluate drug safety, efficacy, and optimal dosing. Their work helps predict human responses to drugs and supports regulatory submissions. DMPK Scientists collaborate with chemists, biologists, and clinicians to optimize drug candidates for development.

What are the key skills and qualifications needed to thrive as a DMPK scientist?

A Dmpk Scientist should possess a strong background in pharmacokinetics, pharmacodynamics, bioanalytical chemistry, and typically hold an advanced degree in pharmaceutical sciences or a related field. Familiarity with laboratory automation systems, LC-MS/MS, and relevant software for data analysis (such as WinNonlin or Phoenix) is frequently required. Demonstrating attention to detail, effective communication, and problem-solving skills helps individuals excel in cross-functional team environments. These abilities are vital for advancing drug discovery projects, ensuring accurate data interpretation, and complying with regulatory standards.

What types of projects and collaborations are typical for a DMPK scientist in a pharmaceutical company?

Dmpk Scientists often work on multidisciplinary project teams involved in drug discovery and development, collaborating closely with medicinal chemists, toxicologists, and biologists. Their typical responsibilities include designing and interpreting ADME (absorption, distribution, metabolism, and excretion) studies, evaluating pharmacokinetic profiles, and contributing data for regulatory submissions. Collaboration is key, as Dmpk Scientists must effectively communicate results and recommendations to both technical and non-technical stakeholders. This collaborative environment fosters professional growth and enables direct impact on the progression of therapeutic candidates through the drug development pipeline.

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Cities with the most Dmpk Scientist job openings:

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Infographic showing various Dmpk Scientist job openings in the United States as of August 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution, with an average salary of $130,117 per year, or $62.6 per hour.

DMPK Scientist, Bioanalytical

Frontage Laboratories

Exton, PA • On-site

Full-time

Re-posted yesterday


Job description

 

ABOUT

Frontage Laboratories is a CRO / Clinical Research Organization providing integrated, science-driven, product development services throughout the drug discovery and development process to enable life science companies to achieve their drug development goals. We have enabled many innovator, generic and consumer health companies of all sizes to file IND, NDA, ANDA, BLA and 505(b)(2) submissions in global markets allowing for successful development of important therapies and products for patients. We are committed to providing rigorous scientific expertise to ensure the highest quality and compliance.  We have successfully assisted clients to advance hundreds of molecules through development to commercial launch in global markets. Come and join us to make a world of difference.

DMPK

The DMPK/ Drug Metabolism and Pharmacokinetics group is dedicated to enabling the discovery, development and commercialization of safe and effective medicines by elucidating the absorption, distribution, metabolism, excretion and pharmacokinetic properties of small molecule drug candidates. We accomplish this through the application of state-of-the-art technologies and sciences of bioanalysis, drug metabolism, drug transport and pharmacokinetics. The DMPK group works in close partnership with disciplines such as medicinal chemistry, pharmacology, toxicology, pharmaceutical sciences, clinical pharmacology and regulatory to optimize leads, select clinical candidates, conduct preclinical development studies, support clinical evaluation and contribute to IND and NDA filings.

Position Summary

The department of Drug Metabolism and Pharmacokinetics (DMPK) at Frontage is seeking a highly motivated candidate with biology or chemistry background (BS, MS or PhD).  This position requires an understanding of bioanalytical techniques. This person will work as a member of our DMPK drug development group and will be responsible for performing a variety of drug analysis of PK studies with guidance from senior members of the team. It is expected the individual selected for this position will receive appropriate trainings in handling radioactive compounds/samples and in the operation of analytical instruments such as HPLC and mass spectrometers.  

Responsibilities

•    Develop bioanalytical (especially) LC/MS/MS methods for discovery and development compounds

•    Verify and qualify LC/MS/MS methods as needed for studies requiring more stringent bio-analytical criteria

•    Work in a high pace environment in developing methods to analyze biological samples (e.g. plasma) from PK and in vitro metabolism studies requiring quantitative information.

•    Assist in the preparation of study reports for studies involving bioanalysis of samples

•    Ensure that all studies are conducted in a timely manner while maintaining highest quality of data 

•    Maintain a record of all studies in appropriate notebooks as per Frontage SOPs.

•    Follow Frontage SOPs, DMPK guidelines, and study protocols while conducting studies.  

•    Ensure all laboratory operation and record-keeping are of high quality and compliant with Frontage SOPs or other applicable regulations.

•    Work with Study Directors/Sponsors in study design, protocol preparation, and overseeing conduct of studies if needed.

•    Effectively manage numerous tasks/projects simultaneously to meet internal/external deadlines while maintaining organizational integration within the DMPK team.

Requirements

•    BS or MS or PhD with 0-3 years relevant experience in any of the pharmaceutical sciences including pharmacokinetics, in vitro and in vivo metabolism, mass spectrometry or analytical chemistry.  

•    Knowledge of LC/MS/MS analytical techniques will be a plus.

•    Broad post-graduate experience in DMPK (for PhD positions) as demonstrated through publications will be a plus but not essential.

•    Compensation commensurate with education and the experience.