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At AstraZeneca we work together across global boundaries to make an impact and find answers to challenges. We do this with the utmost integrity even in the most difficult situations because we are committed to doing the right thing. We continuously forge partnerships that help pursue world-class medicines in new ways, combining our people's exceptional skills with those of people from all over the globe. AstraZeneca holds an outstanding position in CVRM disease, with a range of medicines both on the market and in development, with an industry leading pipeline.
The US Head of Medical - Dyslipidemia is a leadership position that reports directly to the VP Medical Cardiovascular Renal Metabolism (CVRM), within the BioPharmaceuticals Business Unit's US Medical CVRM franchise. The successful candidate will lead a team to develop product and disease area strategies and drive product launches for our novel oral PCSK9 inhibitor across the life-cycle.
What you'll do:

• Build and lead the dyslipidemia medical team, with accountability for the development and execution of disease area and brand strategies and plans
• Accountable for disease area and brand budget and resource requirements
• Partner effectively with the Commercial Lead, role-modeling effective teamwork across the enterprise
• Effectively act as the US point of contact for the Global Product Team (GPT)
• Provide the US viewpoint into life-cycle management/phase IV strategy and study design
• Develop and maintain positive relationships with key external and internal customers
• Anticipate future trends and needs in the marketplace
• Coach, mentor and performance lead direct reports and take an active role in succession and talent management
• Develop and foster a team culture that encourages continued growth and recognition
• Collaborate and build internal and external networks
• Deliver results in a sophisticated matrix environment, building capabilities, and leading large scale impactful medical initiatives
• Lead the of launch of new products
• Leverage AI and digital driven analytics, platforms and clinical solutions to improve medical planning, scientific engagement, evidence generation and patient outcomes
• Ensure compliance with all AZ corporate policies

Requirements for the role:

• Sophisticated Scientific Degree (MBBS, PharmD, PhD, or MD) or equivalent education
• A minimum of 7 years of experience in the pharmaceutical industry, ideally in Medical Affairs and in the dyslipidemia space
• A minimum of 5 years of experience leading high performing teams in the pharmaceutical industry
• Medical/clinical/scientific expertise in CVRM
• US Regulatory Strategy Knowledge/Experience, including new product approval, labeling requirements/negotiations
• Strong business acumen, with comprehensive understanding of the U.S. healthcare environment

Desirable Skills/Experience

• Phase 3b/4 and post-approval dedication research including leading all aspects of patient registries and REMS programs
• Translational medicine, population-based real-world research
• Bridging with coordinated care management & Quality improvement pathways
• Understanding of Health Outcomes Research including Patient-reported outcomes
• Experience integrating emerging technologies-such as AI-supported insights, machine learning tools, or digital medical platforms-into medical affairs strategies or operational processes.

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace, and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.
Join our globally renowned CVRM team. It's an exciting time to join as we work towards our big ambitions with entrepreneurial thinking and innovation. It's up to us to find solutions and act fast to make them happen.
Ready to make a difference? Apply today!
Date Posted
03-Sept-2026
Closing Date
10-Sept-2026
Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.