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Director Real World Evidence Jobs in Raleigh, NC

IQVIA

RWE Clinical Project Manager

Durham, NC

$93K - $232K/yr

Job Overview IQVIA is hiring a clinical project manager to expand our dedicated Real World Evidence (RWE) FSP team, working fully within the environment of a prominent pharma company. In this role ...

NCBiotech

Medical Director, Infectious Diseases

Cary, NC · On-site

$240 - $250/hr

The Medical Director, Infectious Diseases is a core member of the Medical Affairs leadership team ... Contributes to the medical evidence generation strategy, including real-world evidence (RWE ...

Sobi

Hematology Medical Director, VEXAS

Raleigh, NC · On-site

... Director, VEXAS leads medical strategy and external engagement for the VEXAS disease area within ... Contribute to evidence generation projects, real-world evidence studies, and publications ...

Sobi

Hematology Medical Director, VEXAS

Raleigh, NC

... Director, VEXAS leads medical strategy and external engagement for the VEXAS disease area within ... Contribute to evidence generation projects, real-world evidence studies, and publications ...

Sobi

Hematology Medical Director, VEXAS

Raleigh, NC

... Director, VEXAS leads medical strategy and external engagement for the VEXAS disease area within ... Contribute to evidence generation projects, real-world evidence studies, and publications ...

NCBiotech

Hematology Medical Director, VEXAS

Raleigh, NC · On-site

$170 - $245/hr

... Director, VEXAS leads medical strategy and external engagement for the VEXAS disease area within ... Contribute to evidence generation projects, real-world evidence studies, and publications ...

Sobi

Hematology Medical Director, VEXAS

Raleigh, NC

... Director, VEXAS leads medical strategy and external engagement for the VEXAS disease area within ... Contribute to evidence generation projects, real-world evidence studies, and publications ...

Sobi

Hematology Medical Director, VEXAS

Raleigh, NC

... Director, VEXAS leads medical strategy and external engagement for the VEXAS disease area within ... Contribute to evidence generation projects, real-world evidence studies, and publications ...

Sobi

Hematology Medical Director, VEXAS

Raleigh, NC · On-site +1

... Director, VEXAS leads medical strategy and external engagement for the VEXAS disease area within ... Contribute to evidence generation projects, real-world evidence studies, and publications ...

Sobi

Hematology Medical Director, VEXAS

Raleigh, NC

... Director, VEXAS leads medical strategy and external engagement for the VEXAS disease area within ... Contribute to evidence generation projects, real-world evidence studies, and publications ...

Sobi

Hematology Medical Director, VEXAS

Raleigh, NC

... Director, VEXAS leads medical strategy and external engagement for the VEXAS disease area within ... Contribute to evidence generation projects, real-world evidence studies, and publications ...

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Showing results 21-40

All JobsReal World Evidence JobsDirector Real World Evidence JobsDirector Real World Evidence Jobs in Raleigh, NC

Director Real World Evidence information

See Raleigh, NC salary details

$46.7K

$120.5K

$179.3K

How much do director real world evidence jobs pay per year?

As of Aug 9, 2026, the average yearly pay for director real world evidence in Raleigh, NC is $120,494.00, according to ZipRecruiter salary data. Most workers in this role earn between $103,000.00 and $133,200.00 per year, depending on experience, location, and employer.

What is the difference between Director Real World Evidence vs Clinical Data Manager?

AspectDirector Real World EvidenceClinical Data Manager
Required CredentialsAdvanced degree (PhD, MD, or Master’s), experience in RWE, biostatisticsBachelor’s or Master’s in life sciences, clinical research, or related field
Work EnvironmentStrategic, cross-functional teams, focus on observational studiesData collection, database management, clinical trial support
Employer & Industry UsagePharmaceutical, biotech companies, healthcare analyticsClinical research organizations, hospitals, pharma companies
Common Search & Comparison IntentUnderstanding senior roles in RWEOperational data management roles in clinical trials

The main difference is that the Director of Real World Evidence focuses on strategic analysis of observational data to inform healthcare decisions, while a Clinical Data Manager handles the operational aspects of managing clinical trial data. Both roles require strong scientific backgrounds but differ in scope and responsibilities.

What is a director of real world evidence?

A Director of Real World Evidence (RWE) is a senior professional in the healthcare or pharmaceutical industry responsible for overseeing the collection and analysis of real-world data to generate insights about the use, safety, and effectiveness of medical products. They lead teams that design and implement studies using data from sources like electronic health records, insurance claims, and patient registries. Their work helps inform regulatory decisions, support product development, and improve patient outcomes. The role requires expertise in epidemiology, data science, and regulatory requirements, as well as strong leadership and communication skills.

What are the key skills and qualifications needed to thrive as a director of real world evidence, and why are they important?

To thrive as a Director of Real World Evidence, you need advanced expertise in epidemiology, biostatistics, and data analytics, typically supported by a graduate degree in a related field and significant experience in pharmaceutical or healthcare research. Mastery of statistical software (such as SAS, R, or Python), familiarity with real-world data sources (like claims or EMR databases), and knowledge of regulatory guidelines are crucial. Exceptional leadership, communication, and stakeholder management skills distinguish top performers in this role. These competencies ensure robust evidence generation, effective cross-functional collaboration, and impactful decision-making that drives value for healthcare organizations.

How does a director of real world evidence collaborate with cross-functional teams to drive evidence generation projects?

A Director of Real World Evidence (RWE) works closely with clinical, regulatory, medical affairs, biostatistics, and data science teams to design and execute studies that generate actionable insights from real-world data. This role often involves leading project teams, aligning stakeholder objectives, and ensuring that RWE strategies support both product development and post-market decision-making. Effective communication and project management skills are essential, as the Director must synthesize input from diverse experts, manage timelines, and ensure that evidence generation aligns with regulatory and business goals.
What are the most commonly searched types of Real World Evidence jobs in Raleigh, NC? The most popular types of Real World Evidence jobs in Raleigh, NC are:
What job categories do people searching Director Real World Evidence jobs in Raleigh, NC look for? The top searched job categories for Director Real World Evidence jobs in Raleigh, NC are:
What cities near Raleigh, NC are hiring for Director Real World Evidence jobs? Cities near Raleigh, NC with the most Director Real World Evidence job openings:
Director Real World Evidence jobs near you
Infographic showing various Director Real World Evidence job openings in Raleigh, NC as of August 2026, with employment types broken down into 1% Internship, 76% Full Time, 18% Part Time, and 5% Contract. Highlights an 92% Physical, 2% Hybrid, and 6% Remote job distribution, with an average salary of $120,494 per year, or $57.9 per hour.

Senior Epidemiologist, HIV Treatment, Retrospective Claims Study Expertise (FSP Sponsor Dedicated)

IQVIA, Inc.

Durham, NC • On-site

Full-time

Re-posted 5 days ago

IQVIA rating

8.1

Company rating: 8.1 out of 10

Based on 53 frontline employees who took The Breakroom Quiz

62nd of 223 rated it services

Job description

Location: Remote, candidates must be US-based
Join IQVIA's Sponsor-Dedicated FSP team and help advance healthcare through real-world evidence. We bring together scientific expertise and real-world data to help sponsors make decisions and accelerate evidence generation to improve patient outcomes. In this role, you'll work closely with one sponsor, gaining deep knowledge of their therapies while leveraging IQVIA's global expertise.
Core Function Description:
Design and conduct epidemiological studies to generate real-world evidence within time, budget, and quality standards, including but not limited to natural history of disease, population characterization, assessment of treatment patterns and unmet need, development of external comparators, benchmarking of clinical outcomes, comparative safety and effectiveness research, and post-authorization studies. Skill sets of the Epidemiologist role are similarly required, with the expectation of more experience, able to operate strategically under limited supervision, well versed in current Epidemiology research methods, deep understanding of how RWE fits within drug development, regulatory, medical, safety and other functions.
Required Experience
  • Lead development of study protocols, analysis plans, and study reports to answer research questions of priority to RWE.
  • Lead, design, and manage epidemiological, biomarker and/or data science projects.
  • Lead, plan, design, and conduct analyses for internal and external decision making (e.g., responses to regulatory authorities, rapid analyses of safety queries).
  • Lead the identification of fit-for-purpose data for the timely execution of the RWE strategy.
  • Constructed cohorts using RWD sources (e.g., claims, EHR) and evaluate key variables, including diagnosis and procedures codes, and plan validation studies as needed.
  • Contribute to the communication of observational research results and methods, including development of pertinent sections of regulatory documents, reports, publications, white papers.
  • Support the effective communication of study/analysis results to support internal and external decisions.
  • Coauthor abstracts and manuscripts for external dissemination of methodologic study results.
  • Contribute to the development of processes and training aimed at increasing the efficiency, quality, and impact of functional activities.

Technical Expertise:
  • Observational research methods (both Primary and Secondary), deep knowledge of biostatistics and analysis methods, understanding of regulatory processes.
  • Ability to design studies independently, (i.e., ability to translate research questions to create study design).

Subject Matter Expertise:
  • Provide subject matter expertise and conduct analyses for descriptive and comparative research using RWD (examples include claims, EHR, PRO/COA, registry data) for methodologic research questions.
  • Deep, hands-on familiarity with EHR data curation behind health system firewalls, including practical knowledge of where key clinical outcomes are captured across data tables.
  • Expert knowledge and extensive experience with pharmacoepi methods (i.e., signal detection and validation methods).
  • Leverage RWE expertise to identify evidence gaps and develop options to address the evidence gaps in support of Clinical Development Programs.

Minimum Qualifications
  • PhD in Epidemiology with a minimum of 4 years of relevant post-doctoral experience, preferably within a pharmaceutical company or pharma consulting environment. Master's degree in epidemiology plus 7-9 years of experience in lieu of PhD may be acceptable.
  • Extensive experience in retrospective claims data studies required. Focused data sources are mainly US (some ex-US) claims data and lab data.
  • Experience in HIV treatment, defining complex treatment patterns required.
  • Deep understanding of observational research methods and experience to support the design and conduct of observational research, including protocol, statistical analysis plan, and study report development.
  • A record of scientific publications demonstrating expertise in observational study design, analysis, and interpretation is preferred.
  • Demonstrated ability to function with an increasing level of autonomy and to develop productive cross- functional collaborations in a matrix environment.
  • Ability to manage priorities and performance targets.

What's in it for you?
  • Be part of a forward-thinking team that helps shape the next generation of evidence-based healthcare.
  • Work hand-in-hand with one leading sponsor, gaining deep expertise in their therapies.
  • Access IQVIA's global network who supports your growth.

This is your chance to make an impact, while building a career that matters.
IQVIA is a leading global provider of clinical research services, commercial insights and healthcare intelligence to the life sciences and healthcare industries. We create intelligent connections to accelerate the development and commercialization of innovative medical treatments to help improve patient outcomes and population health worldwide. Learn more at https://jobs.iqvia.com
IQVIA is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, status as a protected veteran, or any other status protected by applicable law. https://jobs.iqvia.com/eoe
IQVIA is committed to integrity in our hiring process and maintains a zero tolerance policy for candidate fraud. All information and credentials submitted in your application must be truthful and complete. Any false statements, misrepresentations, or material omissions during the recruitment process will result in immediate disqualification of your application, or termination of employment if discovered later, in accordance with applicable law. We appreciate your honesty and professionalism.
The potential base pay range for this role, when annualized, is $109,200.00 - $273,000.00. The actual base pay offered may vary based on a number of factors including job-related qualifications such as knowledge, skills, education, and experience; location; and/or schedule (full or part-time). Dependent on the position offered, incentive plans, bonuses, and/or other forms of compensation may be offered, in addition to a range of health and welfare and/or other benefits.

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About IQVIA

Sourced by ZipRecruiter

At IQVIA, we are passionate about helping customers and partners improve results and patient outcomes. Everything we do contributes to this vision for creating a healthier world. In today’s healthcare environment, it’s not only about how much data, information, and technology you have at your fingertips – it’s what you do with it. IQVIA is focused on making intelligent connections for customers across the entire healthcare ecosystem to help you drive healthcare forward. Whether that means partnering with novel technology companies to boost patient engagement, leveraging AI & machine learning to accelerate results, or using decentralized trials to reach the right patients wherever they are – we are always looking for smarter ways to move you forward.

Industry

Health care and social assistance

Company size

10,000+ Employees

Headquarters location

Durham, NC, US

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