ZipRecruiter

Log In

1

Director Program Management Office Jobs (NOW HIRING)

OneArc

Director of Program Management

Orlando, FL · On-site

The Director of Program Management manages the Program Management Office (PMO). The PMO is chartered with developing the project execution framework to ensure consistency in project management ...

previous page

Showing results 41-60

All JobsProgram Management Office JobsDirector Program Management Office Jobs

Director Program Management Office information

See salary details

$32K

$109.1K

$183K

How much do director program management office jobs pay per year?

As of Aug 11, 2026, the average yearly pay for director program management office in the United States is $109,055.00, according to ZipRecruiter salary data. Most workers in this role earn between $85,000.00 and $116,500.00 per year, depending on experience, location, and employer.

What is the difference between Director Program Management Office vs Program Manager?

AspectDirector Program Management OfficeProgram Manager
ResponsibilitiesOversees multiple projects, strategic planning, and PMO policiesManages individual projects, coordinates teams, and ensures project delivery
Required CredentialsTypically requires PMP, PMI-ACP, or similar certifications; extensive experienceOften requires PMP or similar; less senior experience needed
Work EnvironmentStrategic, leadership-focused, executive interactionsOperational, team-focused, project execution
Industry UsageCommon in large organizations with established PMOsWidely used across industries for project execution

The main difference is that the Director Program Management Office focuses on strategic oversight and managing the PMO, while the Program Manager handles specific projects and day-to-day project coordination. Both roles require project management certifications, but the Director role involves higher-level planning and leadership responsibilities.

What cities are hiring for Director Program Management Office jobs? Cities with the most Director Program Management Office job openings:
What are the most commonly searched types of Program Management Office jobs? The most popular types of Program Management Office jobs are:
What states have the most Director Program Management Office jobs? States with the most job openings for Director Program Management Office jobs include:
Director Program Management Office jobs near you
Infographic showing various Director Program Management Office job openings in the United States as of August 2026, with employment types broken down into 1% As Needed, 82% Full Time, 14% Part Time, and 3% Contract. Highlights an 92% Physical, 3% Hybrid, and 5% Remote job distribution, with an average salary of $109,055 per year, or $52.4 per hour.

Director Program Manager, Product Launch (Rare Disease)

Rezolute

Redwood City, CA • On-site

$285K - $298K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 4 days ago

Job description

Rezolute is a late-stage rare disease company focused on significantly improving outcomes for individuals with hypoglycemia caused by hyperinsulinism (HI). Our antibody therapy, RZ358 (ersodetug), is designed to treat all forms of HI and has shown substantial benefit in clinical trials and real-world use for the treatment of congenital hyperinsulinism (cHI) and tumor hyperinsulinism (tHI)
The Director Program Manager will be a key member of the Program Management Office (PMO), responsible for Launch execution plan for the company's first rare disease drug launch. This individual will partner closely with key stakeholders and executives from Commercial, Medical Affairs, Regulatory, Manufacturing, Supply Chain to ensure operational readiness and alignment on critical path deliverables.
This role requires a proactive leader with exceptional organizational skills, strategic thinking, and the ability to influence without direct authority in a fast-paced, evolving environment.
Location: Redwood City California (in office role with travel as needed)
Key Responsibilities
  • Leads, facilitates, coordinates and guides all aspects of the Launch Plan, working closely with the Launch Team Leader (s) to enable a program to market.
  • Serve as the central point of coordination and communication to ensure the completeness and accuracy of the launch plan, its defined activities, timelines, and interdependencies.
  • The role will coordinate daily between the PMO and Commercial team Chief of Staff, maintaining and aligning the launch plan. The role will closely monitor tasks and deliverables, measuring variances, outlining risks and adjusting the plan to reflect change.
  • Supports cross-functional launch team meetings and ensure clear ownership, alignment, and accountability of tasks, milestones and deliverables in the Launch plan.
  • Develop and maintain dashboards, reports, and KPIs to track launch readiness and identify risks, gaps, and mitigations, supporting the consolidation and input into the enterprise PMO.
  • Support decision-making by ensuring timely escalation of critical issues and alignment with senior leadership.
  • Drive adherence to program governance, PMO best practices, and change control processes while working within the culture of the teams and company to obtain by in.
  • Build strong, trust-based relationships with functional leaders and project team members to drive collaboration and transparency.
  • Provide program management support to post-launch transition activities as needed.

Qualifications
  • Bachelor's degree required; advanced degree (MBA, MS) preferred.
  • 8+ years of experience in program or project management in the biopharmaceutical industry, with at least 3 years leading or supporting a commercial launch and/or pre-commercial readiness activity in rare disease.
  • Demonstrated familiarity / working knowledge of key commercialization functions in conduct of a rare disease product launch; Experience in rare disease, specialty products, or first-launch environments strongly preferred.
  • Demonstrated ability to manage complex, cross-functional projects and align diverse stakeholders.
  • Strong understanding of commercialization processes and timelines in the life sciences industry.
  • Excellent organizational, communication, and presentation skills.
  • Proficiency with project management tools (e.g., Smartsheet, MS Project) and collaboration platforms.
  • PMP or related certification a plus.

Key Competencies
  • Strategic and structured problem solver with strong critical thinking.
  • Highly collaborative and able to influence without authority.
  • Able to thrive in ambiguity and adapt quickly to changing priorities.
  • Results-driven with a sense of urgency and accountability.
  • Strong interpersonal and relationship-building skills.

Rezolute (RZLT) currently anticipates the base salary for the Director Program Manager role could range from $240,000 to $290,000 and will depend, in part, on the successful candidate's geographical location and their qualifications for the role, including education and experience. This position will also be eligible for an annual performance bonus in accordance with the terms of the applicable plan (depending, in part, on company and individual performance and at the Company's discretion on an individual basis). The compensation described above is subject to change and could be higher or lower than the range described based on current market survey data and the qualifications, education, experience, and geographical location of the selected candidate.
Qualifying employees are eligible to participate in benefit programs such as:
  • Health Insurance (Medical / Dental / Vision)
  • Disability, Life & Long-Term Care Insurance
  • Holiday Pay
  • Tracking Free Vacation Program
  • 401(k) Plan Match
  • Educational Assistance Benefit
  • Fitness Center Reimbursement

We are an Equal Opportunity Employer and do not discriminate against applicants due to race, ethnicity, gender, veteran status, or on the basis of disability or any other federal, state or local protected class.
We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.

Apply