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Director Operations Excellence Jobs in Boston, MA

Ipsen Group

Director, U.S. Operational Excellence

Cambridge, MA · On-site

$177 - $260/hr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Director, U.S. Operational Excellence**Company:**Ipsen Biopharmaceuticals Inc.**About Ipsen:**Ipsen ... S. Field Operations, responsible for orchestrating the day-to-day execution of high-impact ...

Ipsen

Director, U.S. Operational Excellence

Cambridge, MA · On-site

$177K - $260K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Title: Director, U.S. Operational Excellence Company: Ipsen Biopharmaceuticals Inc. About Ipsen ... S. Field Operations, responsible for orchestrating the day-to-day execution of high-impact ...

UNAVAILABLE

Director, Operations Finance

Boston, MA · On-site

$160 - $190/hr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

... excellence (while having fun!) in everything they do. Joining the PF family means being part of a ... Overview The Director, Operations Finance is responsible for leading the financial planning ...

Planet Fitness

Director, Operations Finance

Boston, MA · On-site

$160 - $190/hr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

... excellence (while having fun!) in everything they do. Joining the PF family means being part of a ... Overview The Director, Operations Finance is responsible for leading the financial planning ...

Formlabs

Operational Excellence Lead

Boston, MA · On-site

  • Medical

  • Dental

  • Vision

  • Retirement

As an Operations Excellence Lead you will work at the cross section of business, operations, and ... Compensation We are all owners of Formlabs and direct beneficiaries of our success. We believe that ...

Formlabs

Operational Excellence Lead

Somerville, MA · On-site

  • Medical

  • Dental

  • Vision

  • Retirement

As an Operations Excellence Lead you will work at the cross section of business, operations, and ... Compensation We are all owners of Formlabs and direct beneficiaries of our success. We believe that ...

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Director Operations Excellence information

See Boston, MA salary details

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$195K

How much do director operations excellence jobs pay per year?

As of Aug 18, 2026, the average yearly pay for director operations excellence in Boston, MA is $116,984.00, according to ZipRecruiter salary data. Most workers in this role earn between $82,000.00 and $147,200.00 per year, depending on experience, location, and employer.

What does a director of operations excellence do?

A Director of Operations Excellence is responsible for overseeing and improving organizational processes to enhance efficiency, productivity, and quality across various departments. They develop and implement strategies, best practices, and continuous improvement initiatives such as Lean or Six Sigma methodologies. This role involves analyzing performance metrics, identifying areas for operational improvement, and leading cross-functional teams to achieve business goals. Directors of Operations Excellence also ensure compliance with industry standards and help drive a culture of excellence within the organization.

What are the key skills and qualifications needed to thrive as a director of operations excellence?

To thrive as a Director of Operations Excellence, you need expertise in process improvement, project management, and strategic planning, usually supported by a bachelor’s or master’s degree in business, engineering, or a related field. Familiarity with Lean, Six Sigma, ERP systems, and certifications like PMP or Six Sigma Black Belt are commonly required. Exceptional leadership, communication, and change management skills help drive cross-functional initiatives and foster a culture of continuous improvement. These skills and qualifications are vital for optimizing organizational efficiency, ensuring sustainable growth, and delivering operational results.

How does a director of operations excellence typically drive cross-functional collaboration to improve organizational processes?

A Director of Operations Excellence often leads initiatives that require close collaboration with departments such as supply chain, finance, IT, and quality assurance. They facilitate workshops, set up process improvement teams, and establish clear communication channels to ensure alignment on goals and timelines. By leveraging data-driven insights and best practices, they help teams identify inefficiencies, implement standardized processes, and measure outcomes. This collaborative approach not only accelerates improvement efforts but also fosters a culture of continuous innovation across the organization.

What is the difference between Director Operations Excellence vs Operations Manager?

AspectDirector Operations ExcellenceOperations Manager
ResponsibilitiesStrategic process improvement, cross-departmental initiatives, long-term efficiency goalsDay-to-day operations management, team supervision, short-term problem solving
Required CredentialsTypically bachelor's degree, certifications in Lean, Six Sigma, or process improvementUsually bachelor's degree, experience in operations, certifications may be beneficial
Work EnvironmentStrategic planning sessions, corporate offices, cross-functional teamsOperational sites, team management, direct interaction with staff

The main difference is that the Director Operations Excellence focuses on strategic, organization-wide process improvements and long-term efficiency initiatives, while the Operations Manager handles daily operational activities and team supervision. Both roles often require similar certifications like Lean or Six Sigma but differ in scope and focus.

What are the most commonly searched types of Operations Excellence jobs in Boston, MA?

The most popular types of Operations Excellence jobs in Boston, MA are:

What job categories do people searching Director Operations Excellence jobs in Boston, MA look for?

The top searched job categories for Director Operations Excellence jobs in Boston, MA are:

What cities near Boston, MA are hiring for Director Operations Excellence jobs?

Cities near Boston, MA with the most Director Operations Excellence job openings:

Director Operations Excellence jobs near you
Infographic showing various Director Operations Excellence job openings in Boston, MA as of August 2026, with employment types broken down into 1% As Needed, 82% Full Time, 12% Part Time, 1% Temporary, 3% Contract, and 1% Nights. Highlights an 94% Physical, 2% Hybrid, and 4% Remote job distribution, with an average salary of $116,984 per year, or $56.2 per hour.

Director, Clinical Operations Excellence

Relay Therapeutics

Cambridge, MA • On-site

$163K - $233K/yr

Full-time

Posted 12 days ago

Job description

The Opportunity:
The Director, Clinical Operations Excellence will establish and advance scalable, fit-for-purpose operational capabilities that enable high-quality, inspection-ready clinical trial execution across Relay's portfolio, reporting to the VP, Clinical Operations Excellence. In a lean, matrixed biotechnology environment, this role will serve as both a strategic leader and hands-on contributor, partnering with study teams, functional stakeholders, CROs, and vendors to strengthen execution, simplify processes, develop actionable operational metrics and analytics, and proactively manage operational and quality risks. As the functional lead and business process owner for Risk-Based Quality Management (RBQM), this individual will be accountable for the implementation, adoption, and continuous improvement of Relay's RBQM framework in collaboration with relevant vendors and CROs. The role will ensure study teams apply quality risk management principles, leverage RBQM technologies, operational analytics, and data-driven oversight, and act on emerging risks in a timely and effective manner.
Your Role:
  • Clinical Operations Excellence: Lead portfolio-level process improvement and operational excellence initiatives that improve study execution, quality, consistency, efficiency, and inspection readiness.
  • Partner with Clinical Operations, Clinical Development, Medical, Biometrics, Quality, Regulatory, Safety, TMF, CROs, and external providers to ensure studies are operationally feasible, risk-informed, and consistently executed.
  • RBQM Leadership: Serve as Relay's RBQM subject matter expert and business process owner, accountable for the framework, governance, adoption, and continuous improvement of RBQM practices across studies.
  • Lead study teams through CtQ identification, critical data and process review, risk assessments, quality controls, KRIs, QTLs, mitigation planning, risk ownership, escalation pathways, and ongoing risk review.
  • Integrate RBQM into protocol development, study planning, vendor oversight, monitoring strategies, data review, governance forums, issue management, and inspection readiness.
  • Systems, Metrics, and Data-Driven Oversight: Build, review, and execute operational metrics and reporting capabilities that provide clear visibility into study execution, portfolio performance, quality trends, and areas requiring action.
  • Partner with study teams and functional stakeholders to interpret metrics, identify trends, support governance discussions, and translate insights into practical actions that improve execution and quality.
  • Vendor Oversight and Governance: Support execution of the vendor governance strategy by organizing and facilitating governance forums, tracking decisions and actions, supporting performance oversight, issue escalation, corrective action follow-up, quality trend review, and RBQM operationalization.
  • Process Excellence and Inspection Readiness: Develop and improve SOPs, work instructions, templates, playbooks, job aids, governance models, operational metrics, and inspection readiness standards.
  • Champion simple, scalable, quality-focused ways of working that support audit readiness, inspection preparation, CAPA development, root cause analysis, and continuous improvement.

Your Background:
  • BA/BS degree in Life Sciences, Nursing, Pharmacy, Public Health, or related discipline required; advanced degree preferred.
  • 8+ years of progressive Clinical Operations experience or equivalent experience, in biotechnology, pharmaceutical, or CRO organizations, including global Phase I-III oncology or other complex clinical development programs.
  • Demonstrated experience leading or implementing RBQM, operational strategy, or process improvement initiatives in a fast-paced, matrixed environment.
  • Strong expertise in study management, monitoring, vendor oversight, clinical trial execution, issue management, inspection readiness, and Quality Risk Management.
  • Experience with CtQ factors, critical data and processes, KRIs, QTLs, centralized monitoring, risk mitigation, and RBQM platforms.
  • Experience building, reviewing, and using operational metrics, dashboards, or reporting capabilities to support study execution, governance, and continuous improvement.
  • Strong knowledge of GCP, ICH E6(R3), ICH E8(R1), RBQM principles, FDA, EMA, and other applicable regulatory expectations.
  • Collaborative, hands-on, and comfortable operating in ambiguity, with excellent facilitation, analytical, communication, presentation, project management, and influencing skills.
  • Proven ability to present complex concepts clearly and persuasively.
  • Demonstrated ability to lead through influence and, where applicable, manage or mentor team members.
  • Strong stakeholder management, negotiation, and influencing capabilities.

Estimated Salary Range: [$163,000 - $233,000]
The range provided above is based on what we believe to be a reasonable estimate for this job at the time of posting. Actual base salary will depend on a number of factors, including but not limited to, a candidate's education, experience, skills and location.
#BP1
About Relay Therapeutics
Relay Therapeutics is a clinical-stage precision medicines company transforming the drug discovery process with the goal of bringing life-changing therapies to patients. Built on unparalleled insights into protein motion and how this dynamic behavior relates to protein function, we aim to effectively drug protein targets that have previously been intractable, with an initial focus on enhancing small molecule therapeutic discovery in targeted oncology. Our Dynamo platform integrates an array of leading-edge experimental and computational approaches to provide a differentiated understanding of protein structure and motion to drug these targets. We have built a world-class team of leading experts from each of these disciplines, and they are driven by a deep collaboration at every step of our drug discovery process.
Our team is equal parts fearless and relentless, with a shared passion for working collaboratively in intellectually stimulating environments. If you're excited by the challenge of putting protein motion at the heart of drug discovery and passionate about making a difference in the lives of patients, join us!

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