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Director Operations Excellence Jobs in California

Ensure safety and operational excellence at all assigned locations with evidence-based ... Lead, direct, and oversee all aspects of people leadership, manufacturing operations and ...

Ensure safety and operational excellence at all assigned locations with evidence-based ... Lead, direct, and oversee all aspects of people leadership, manufacturing operations and ...

The Operations Excellence team within WWRFO drives the execution programs and systems that support ... direct lines of business. - Own the strategy and delivery of the retail execution systems (the ...

Provides strategic and technical leadership for manufacturing scale-up, operational excellence, continuous improvement, and new product introduction within a regulated medical device environment.

Provides strategic and technical leadership for manufacturing scale-up, operational excellence, continuous improvement, and new product introduction within a regulated medical device environment.

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Provides strategic and technical leadership for manufacturing scale-up, operational excellence, continuous improvement, and new product introduction within a regulated medical device environment.

New

Provides strategic and technical leadership for manufacturing scale-up, operational excellence, continuous improvement, and new product introduction within a regulated medical device environment.

New

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Director Operations Excellence information

How does a Director of Operations Excellence typically drive cross-functional collaboration to improve organizational processes?

A Director of Operations Excellence often leads initiatives that require close collaboration with departments such as supply chain, finance, IT, and quality assurance. They facilitate workshops, set up process improvement teams, and establish clear communication channels to ensure alignment on goals and timelines. By leveraging data-driven insights and best practices, they help teams identify inefficiencies, implement standardized processes, and measure outcomes. This collaborative approach not only accelerates improvement efforts but also fosters a culture of continuous innovation across the organization.

What does a Director of Operations Excellence do?

A Director of Operations Excellence is responsible for overseeing and improving organizational processes to enhance efficiency, productivity, and quality across various departments. They develop and implement strategies, best practices, and continuous improvement initiatives such as Lean or Six Sigma methodologies. This role involves analyzing performance metrics, identifying areas for operational improvement, and leading cross-functional teams to achieve business goals. Directors of Operations Excellence also ensure compliance with industry standards and help drive a culture of excellence within the organization.

What are the key skills and qualifications needed to thrive as a Director of Operations Excellence, and why are they important?

To thrive as a Director of Operations Excellence, you need expertise in process improvement, project management, and strategic planning, usually supported by a bachelor’s or master’s degree in business, engineering, or a related field. Familiarity with Lean, Six Sigma, ERP systems, and certifications like PMP or Six Sigma Black Belt are commonly required. Exceptional leadership, communication, and change management skills help drive cross-functional initiatives and foster a culture of continuous improvement. These skills and qualifications are vital for optimizing organizational efficiency, ensuring sustainable growth, and delivering operational results.

What is the difference between Director Operations Excellence vs Operations Manager?

AspectDirector Operations ExcellenceOperations Manager
ResponsibilitiesStrategic process improvement, cross-departmental initiatives, long-term efficiency goalsDay-to-day operations management, team supervision, short-term problem solving
Required CredentialsTypically bachelor's degree, certifications in Lean, Six Sigma, or process improvementUsually bachelor's degree, experience in operations, certifications may be beneficial
Work EnvironmentStrategic planning sessions, corporate offices, cross-functional teamsOperational sites, team management, direct interaction with staff

The main difference is that the Director Operations Excellence focuses on strategic, organization-wide process improvements and long-term efficiency initiatives, while the Operations Manager handles daily operational activities and team supervision. Both roles often require similar certifications like Lean or Six Sigma but differ in scope and focus.

What are the most commonly searched types of Operations Excellence jobs in California? The most popular types of Operations Excellence jobs in California are:
What are popular job titles related to Director Operations Excellence jobs in California? For Director Operations Excellence jobs in California, the most frequently searched job titles are:
What job categories do people searching Director Operations Excellence jobs in California look for? The top searched job categories for Director Operations Excellence jobs in California are:
What cities in California are hiring for Director Operations Excellence jobs? Cities in California with the most Director Operations Excellence job openings:
Infographic showing various Director Operations Excellence job openings in California as of July 2026, with employment types broken down into 1% As Needed, 81% Full Time, 14% Part Time, 1% Temporary, and 3% Contract. Highlights an 92% Physical, 3% Hybrid, and 5% Remote job distribution.

Director Operational Excellence

Research and Testing Laboratory

San Diego, CA • On-site

Full-time

Medical, Dental, Vision, Retirement, PTO

This job post has expired today. Applications are no longer accepted.


Job description

What if the work you did every day could impact the lives of people you know? Or all of humanity?At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients.Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible.

The Operational Excellence Director is a key leader and partner to all functions at Illumina. In this role, you will partner with the leadership team and their functions to drive transformations in support of our company strategy, deploy our Operational Excellence business systems and build self-sustaining capabilities. You thrive on solving complex problems, navigating across various disciplines and functions, and empowering/inspiring/mentoring others to make their work easier and drive improvements with significant business value. This role will also support our AI journey at Illumina and will be instrumental to provide guidance and build capabilities.

Position Summary

  • Leads process improvement initiatives through the disciplined use of measurements, accountability, analysis and discussion of process alternatives to arrive at best practices.

  • Plans, manages, and controls the activities of a team that provides operational support for a business segment, group or team.

  • Brings expertise or identifies subject matter experts in support of multi-functional efforts in process improvement, data capture and analysis, infrastructure support, tool ownership and compliance with procedures, etc.

  • Advises business groups by providing strategic direction to initiative prioritization, integration and resource application.

  • Ensures that policies and procedures align with corporate vision.

  • Drive the adoption, scaling, and impact of AI and intelligent automation across Illumina.

  • Changes to individual responsibilities may occur due to business needs and other related duties may be assigned.

Responsibilities

  • Partner with Sr Leaders and their leadership teams in Lean/Operational Excellence system deployment and maturity

  • Supports and leads complex improvement and optimization projects/initiatives in the areas of Safety, Quality, Productivity and Cost savings

  • Conducts training in continuous improvement methodologies and mentor others in the application of these methods

  • Facilitates/assists business process management and the teams supporting continuous improvement.

  • Contributes to/Drives business process management and helps to ensure sites have installed and are effectively practicing business processes

  • Coordinate stakeholders to develop area specific roadmap as part of site/functional strategy.

  • Lead functions to development, implementation and monitoring of goals and KPI's through strategy deployment

  • Oversees functional Operational Excellence Project Portfolio and chairs the Operational Excellence Steering committee

  • Promote site level communication and sharing through network

Capabilities

  • Partners with executive and functional leadership to drive enterprise transformations that directly support company strategy through the deployment of Operational Excellence business systems.

  • Leads the design, deployment, and sustainment of scalable Operational Excellence management systems (e.g., problem solving, performance management, standard work, and continuous improvement) that deliver measurable business value.

  • Builds selfsustaining continuous improvement capabilities across functions by coaching, mentoring, and empowering leaders and teams to solve complex problems and improve their own work.

  • Sponsors and leads highly complex, crossfunctional improvement initiatives requiring systems thinking, advanced problem solving, and the ability to operate effectively in ambiguous environments.

  • Serves as a trusted advisor and thought partner to senior leaders, influencing decisions through datadriven insights, structured problem solving, and change leadership.

  • Navigates across multiple disciplines and functions to align stakeholders, remove barriers, and embed new ways of working while preserving strong, trustbased relationships.

  • Plays a key role in Illumina's AI journey by providing guidance, governance, and capability building to ensure AI is effectively integrated into Operational Excellence practices.

  • Leads and develops experienced professionals and/or enterprise capabilities, exerting significant influence over improvement priorities, methodologies, and resource deployment through direct, matrixed, or influencebased leadership.

Education & Experience:

  • Bachelor's Degree (or equivalent) in technical/quantitative field

  • Preferred: PhD / MBA / MS Preferred Area of Study: Science, Technology, Engineering, Mathematics

  • Required: 18 years of experience. 10 years in business process transformation/ Operational Excellence deployment and 10 years of Management experience

  • Preferred: 10 years of experience from within a regulated healthcare environment.

  • Strong leader with the ability to establish clear strategy that can inspire others to deliver and influence to drive change

  • across the organization

  • Demonstrated experience in driving continuous improvement culture and operating system across an enterprise and ability to navigate and influence across all levels of an organization, translating strategic vision into tangible outcomes

  • Lean Six Sigma Blackbelt/Master Blackbelt

  • Ability to interact effectively in a complex organization and in ambiguous situations; ability to manage sensitive situations with exceptional judgment and discretion

  • Consistent track record of collaboration, including the ability to work with cross-functional teams, and across complex ecosystems

  • Exceptional written and verbal communications skills (including articulating \ vision, inspiring teams, and presenting to senior executives).

  • Strong sector AND enterprise mindset & strong business/financial acumen

  • Strong negotiation and interpersonal skills required

  • Excellent stakeholder management and networking skills required.

The estimated base salary range for the Director Operational Excellence role based in the United States of America is: $170,600 - $255,800. Should the level or location of the role change during the hiring process, the applicable base pay range may be updated accordingly. The range reflects longterm growth in the role; therefore, most candidates are hired between the minimum and middle of the range. Placement depends on experience, skills, location, and internal equity. Additionally, all employees are eligible for one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package. We offer a wide range of benefits as innovative as our work, including access to genomics sequencing, family planning, health/dental/vision, retirement benefits, and paid time off.
We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility. We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information. Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws. Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process. If you require accommodation to complete the application or interview process, please contact accommodations@illumina.com. To learn more, visit: https://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf. The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants. This role is not eligible for visa sponsorship.