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Director Operational Excellence Jobs in Rochester, MN

... excellence, and unwavering focus on Mayo Clinic's core value: the needs of the patient come first ... Partner with clinical, operational, technical, legal, compliance, and data leaders to advance AI ...

... excellence, and unwavering focus on Mayo Clinic's core value: the needs of the patient come first ... Partner with clinical, operational, technical, legal, compliance, and data leaders to advance AI ...

Executive Director

Rochester, MN · On-site

$120 - $150/hr

... Operations Director, while fostering a culture of excellence, stability, and continuous improvement. Responsibilities * Provide visionary leadership to staff and residents, promoting a culture of ...

Task Associate

Rochester, MN · On-site

$15 - $20/hr

Drive operational excellence by keeping assigned work area replenished, signed, and faced, and ... Execute other operational tasks as directed. JOB QUALIFICATIONS Education * High school diploma is ...

Drive operational excellence by keeping assigned work area replenished, signed, and faced, and ... Execute other operational tasks as directed. JOB QUALIFICATIONS Education * High school diploma is ...

Task Associate

Rochester, MN · On-site

$15 - $20/hr

Drive operational excellence by keeping assigned work area replenished, signed, and faced, and ... Execute other operational tasks as directed. JOB QUALIFICATIONS Education * High school diploma is ...

Integrity, Caring, Teamwork, Toughmindedness, Dedication to Excellence, Discipline, Loyalty, and ... Before project award, works with operations & BD to provide recommendations for the Risk Analysis ...

Drive operational excellence by keeping assigned work area replenished, signed, and faced, and ... Execute other operational tasks as directed. JOB QUALIFICATIONS Education * High school diploma is ...

Drive operational excellence by keeping assigned work area replenished, signed, and faced, and ... Execute other operational tasks as directed. JOB QUALIFICATIONS Education * High school diploma is ...

Safety Director I

Rochester, MN · On-site

$150 - $190/hr

Integrity, Caring, Teamwork, Toughmindedness, Dedication to Excellence, Discipline, Loyalty, and ... Before project award, works with operations & BD to provide recommendations for the Risk Analysis ...

Operational Excellence * Achieve excellence in administrative functions; self-directed with focus on driving operational and financial goals and metrics. * Demonstrate expertise and fluency in ...

Operational Excellence * Achieve excellence in administrative functions; self-directed with focus on driving operational and financial goals and metrics. * Demonstrate expertise and fluency in ...

Operational Excellence * Achieve excellence in administrative functions; self-directed with focus on driving operational and financial goals and metrics. * Demonstrate expertise and fluency in ...

Operational Excellence * Achieve excellence in administrative functions; self-directed with focus on driving operational and financial goals and metrics. * Demonstrate expertise and fluency in ...

Showing results 41-60

Director Operational Excellence information

See Rochester, MN salary details

$34.6K

$109.5K

$182.5K

How much do director operational excellence jobs pay per year?

As of Aug 16, 2026, the average yearly pay for director operational excellence in Rochester, MN is $109,456.00, according to ZipRecruiter salary data. Most workers in this role earn between $76,700.00 and $137,700.00 per year, depending on experience, location, and employer.

What is a director operational excellence?

A Director of Operational Excellence is responsible for driving continuous improvement initiatives across an organization to enhance efficiency, productivity, and quality. They develop strategies, implement best practices, and foster a culture of operational excellence using methodologies like Lean, Six Sigma, and process optimization. Their role involves collaborating with cross-functional teams, analyzing performance metrics, and identifying opportunities for improvement. By streamlining workflows and eliminating inefficiencies, they help the organization achieve cost savings and sustainable growth.

What are the key skills and qualifications needed to thrive in the director operational excellence position, and why are they important?

To excel as a Director Operational Excellence, you need a strong background in process improvement, project management, and strategic leadership, often supported by a relevant bachelor’s or master’s degree. Familiarity with Lean, Six Sigma, and enterprise resource planning (ERP) systems, along with certifications like Lean Six Sigma Black Belt, is highly valued. Exceptional communication, change management, and analytical thinking skills help professionals drive transformation and gain buy-in from cross-functional teams. These qualifications are critical for successfully leading operational initiatives that enhance efficiency, quality, and business performance.

What are the main challenges a director operational excellence typically faces in the role?

Directors of Operational Excellence often encounter challenges such as breaking down organizational silos, managing resistance to change, and standardizing processes across diverse departments or regions. They must navigate complex stakeholder dynamics while implementing process improvements that may disrupt established habits and workflows. Success in this role requires balancing strategic vision with practical execution, ensuring improvements are sustainable and aligned with business goals. Strong leadership and the ability to influence at all levels of the organization are essential for overcoming these challenges.

What job categories do people searching Director Operational Excellence jobs in Rochester, MN look for?

The top searched job categories for Director Operational Excellence jobs in Rochester, MN are:

What cities near Rochester, MN are hiring for Director Operational Excellence jobs?

Cities near Rochester, MN with the most Director Operational Excellence job openings:

Infographic showing various Director Operational Excellence job openings in Rochester, MN as of August 2026, with employment types broken down into 81% Full Time, 17% Part Time, and 2% Contract. Highlights an 93% Physical, 2% Hybrid, and 5% Remote job distribution, with an average salary of $109,456 per year, or $52.6 per hour.

Director - AI Digital Biology

Mayo Clinic

Rochester, MN • Hybrid

Full-time

Medical, Dental, Vision, Retirement

Re-posted 8 days ago


Mayo Clinic rating

7.8

Company rating: 7.8 out of 10

Based on 699 frontline employees who took The Breakroom Quiz

129th of 887 rated healthcare providers


Job description

The Director - Artificial Intelligence (AI) leads the engineering and research team that builds and delivers Mayo Clinic DigPath's digital-biology technology platforms, accountable for translating the organization's vision into validated, deployed products. Working closely with the Vice President, Digital Biology, the Chief Medical Officer, and the Chief Science Officer, the Director helps shape technical direction and owns its execution-the roadmap, delivery, and technical quality for DigPath's core model and platform portfolio, including foundation and task-specific models, AI Virtual Cells, biological digital twins, and digital biomarker discovery. Directing a multidisciplinary team of AI/ML engineers, software developers, and research scientists, the Director turns clinical and scientific priorities into engineering execution - partnering with the CMO for clinical relevance and the CSO for scientific rigor - to consistently ship breakthrough tools with speed, technical excellence, and unwavering focus on Mayo Clinic's core value: the needs of the patient come first.

The Director partners closely with executive leaders, clinical and business stakeholders, and technical teams to ensure AI initiatives are aligned with enterprise strategy, governance expectations, and operational readiness. The role leads multidisciplinary teams across product, operations, and technology and serves as a key connector between strategy and execution.

Key Responsibilities

  • AI Strategy & Program Leadership: Lead development and execution of enterprise AI strategy and multi-year roadmaps aligned with organizational goals.
  • Portfolio Oversight: Oversee intake, prioritization, and sequencing of AI initiatives; balance value, feasibility, risk, and capacity across portfolios.
  • CrossFunctional Leadership: Partner with clinical, operational, technical, legal, compliance, and data leaders to advance AI initiatives from concept through deployment.
  • Governance & Responsible AI: Ensure AI initiatives adhere to governance frameworks, ethical standards, regulatory requirements, and risk management practices.
  • Operational Enablement: Establish operating rhythms, performance metrics, and reporting mechanisms to track progress, outcomes, and value realization.
  • Stakeholder Engagement: Serve as a trusted advisor to senior leaders; communicate AI strategy, progress, and impact through executivelevel updates and presentations.
  • People & Team Leadership: Lead, develop, and support managers and senior professionals; foster a culture of accountability, collaboration, and continuous improvement.
  • Financial & Resource Stewardship: Support budget planning, resource allocation, and business case development for AI initiatives.

Core Competencies

  • Enterprise AI & Digital Strategy
  • Executive Presence & Influence
  • Change Leadership & Resilience
  • Ethical & Responsible AI Stewardship
  • CrossFunctional Collaboration
  • Program & Portfolio Management


This is a hybrid position and incumbent must live within 100 miles of the Rochester, MN campus. 
Mayo Clinic will not sponsor or transfer visas for this position including F1 OPT STEM.

Why Mayo Clinic

Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans - to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.

Benefits Highlights
  • Medical: Multiple plan options.
  • Dental: Delta Dental or reimbursement account for flexible coverage.
  • Vision: Affordable plan with national network.
  • Pre-Tax Savings: HSA and FSAs for eligible expenses.
  • Retirement: Competitive retirement package to secure your future.
Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is. 

Equal Opportunity

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law".  Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.
  • Bachelor's degree and 10 years of progressive experience in healthcare, technology, operations, analytics, or related fields with demonstrated leadership responsibility required.
  • Master's degree and 10 years of progressive experience in healthcare, technology, operations, analytics, or related fields with demonstrated leadership responsibility preferred.
  • Demonstrated experience leading high performing teams and delivering complex enterprise initiatives in a matrixed organizations preferred.

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About Mayo Clinic

Sourced by ZipRecruiter

Mayo Clinic is the largest integrated, not-for-profit medical group practice in the world. We're building the future, one where the best possible care is available to everyone — and more people can heal at home. Our relentless research turns into earlier diagnoses and new cures. That's how we inspire hope in those who need it most. At Mayo Clinic, experts work together to solve the most challenging unmet needs of patients. Our history of innovation dates back almost 150 years, when brothers Will and Charlie Mayo pioneered an integrated, team-based approach to medicine. Today, that trailblazing spirit drives innovations like Mayo Clinic Platform — which powers new technologies to change how care is delivered to all.

Industry

Hospitals

Company size

10,000+ Employees

Headquarters location

Rochester, MN, US

Year founded

1919