Director Informatics Jobs in Boston, MA (NOW HIRING)

Alnylam is seeking a strategic and delivery-oriented technology leader to serve as Associate Director, Laboratory Informatics Platforms This role is responsible for the delivery, evolution, and operational stewardship of core laboratory informatics capabilities that enable scientific, development, and manufacturing-support workflows across Research and Early Development (ReDev) and CMC.
The Associate Director will lead the product and technology delivery of laboratory informatics platforms, including Electronic Lab Notebook (ELN), sample management, entity registration, and workflow orchestration. The role partners closely with scientific, technical operations stakeholders across ReDev and CMC to translate business needs into scalable, compliant, and fit-for-purpose solutions that improve traceability, workflow efficiency, and data quality.
This role does not own QC LIMS systems, which are managed within Quality Technology. Instead, this role partners closely with IT Quality Technology to ensure aligned data models, integrated workflows, and seamless end-to-end laboratory processes across ReDev, CMC, and QC environment.
This position requires a leader who can balance business partnership, product ownership, and disciplined delivery in a regulated environment, while ensuring platforms evolve to support future analytics and AI-driven use cases.
Key Responsibilities
Lead Delivery of Laboratory Informatics Platforms
Own the delivery and lifecycle management of informatics solutions across ELN, sample management, entity registration, and workflow orchestration. Define and execute platform roadmaps aligned with business priorities across ReDev and CMC.
Translate Business Needs into Digital Capabilities
Partner with laboratory, scientific, and technical operations stakeholders to understand workflows and requirements. Design and deliver solutions that improve data capture, process efficiency, traceability, and user experience.
Establish Product and Platform Governance
Drive governance for demand intake, prioritization, release management, and change control. Define standards for configuration, data models, and system usage to ensure consistency and scalability across labs.
Enable End-to-End Laboratory Workflows
Design and deliver integrated workflows that connect experiment execution, sample lifecycle management, entity registration, and result capture.
Partner with Quality Technology to ensure alignment between Laboratory Informatics platforms and QC workflows supported by LIMS, while maintaining clear ownership boundaries.
Lead Instrument Data Capture Strategy
Own the strategy and requirements for instrument data capture across ReDev and CMC environments, and define how instrument-generated data is integrated and contextualized within ELN and related platforms.
Partner with:

• Lab Computing and Facilities Technology for instrument connectivity, deployment, and operations support.
• Quality Technoloy for QC instrument data requirements and compliance expectations.

Partner with Quality Technology on QC Integration
Collaborate closely with the Quality Technology team to enable seamless integration between laboratory informatics platforms and QC LIMS systems.
Ensure alignment on:

• data models and master data (e.g., samples, entities)
• workflow handoffs and traceability
• integration patterns and data flows
• end-to-end process consistency across lab domains

Ensure Compliance, Data Integrity, and Sustainability
Partner with Quality and validation teams to ensure platforms meet applicable compliance and data integrity standards. Support validated system lifecycle practices where applicable and ensure solutions are designed for long-term sustainability and audit readiness.
Partner Across IT and Business Functions
Collaborate with enterprise IT teams (Data/AI, Infrastructure, Security) to ensure platforms are secure, scalable, and integrated with enterprise capabilities. Build strong relationships with business stakeholders and external vendors.
Qualifications
Required

• Bachelor's degree in Computer Science, Engineering, Life Sciences, or related field (or equivalent experience)
• 10-12 years of experience in laboratory informatics, digital lab technology, or related domains within biotech/pharma
• Proven experience delivering or managing platforms such as ELN, sample management, entity registration, or related laboratory systems
• Strong understanding of laboratory workflows across Research and/or CMC environments
• Experience translating business needs into system designs, roadmaps, and delivery plans
• Experience leading cross-functional delivery involving business stakeholders, vendors, and IT teams
• Working knowledge of GxP, Part 11, CSV principles, and data integrity (ALCOA+) as applicable to laboratory systems
• Strong leadership, communication, and stakeholder engagement skills

Preferred

• Advanced degree in Life Sciences, Engineering, or Computer Science
• Experience with workflow orchestration and cross-platform integration in lab environments
• Familiarity with instrument data capture and scientific data models
• Experience with SaaS laboratory platforms and modern vendor ecosystems
• Experience in RNAi, oligonucleotide, or advanced modality environments
• Experience partnering with Quality Technology teams and integrating with QC LIMS systems

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U.S. Pay Range
$172,200.00 - $233,000.00
The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity).
Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together.
Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers
About Alnylam
We are the leader in RNAi therapeutics - a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another.
At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.