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Director Clinical Trial Operations Jobs (NOW HIRING)

Kardigan

Clinical Trial Manager

Princeton, NJ · Remote

As a Clinical Trial Manager (CTM), you will be part of the Clinical Operations team reporting to the asset's Clinical Trial or Clinical Program Lead. This position will be responsible for the ...

Doist

Director, Clinical Operations

San Francisco, CA · On-site

$215K - $240K/yr

Role Overview The Director, Clinical Operations will oversee the strategic and operational ... Th is individual will manage trial budgets, vendor selection, and risk mitigation while ...

ICON

Clinical Trial Manager

Blue Bell, PA · On-site +1

Clinical Operations Lead ICON is a global healthcare intelligence and clinical research ... As a Clinical Trial Manager at ICON, you will manage clinical trial operations activities ...

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As of Sep 12, 2026, the average yearly pay for director clinical trial operations in the United States is $145,969.00, according to ZipRecruiter salary data. Most workers in this role earn between $102,000.00 and $173,500.00 per year, depending on experience, location, and employer.

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Infographic showing various Director Clinical Trial Operations job openings in the United States as of July 2026, with employment types broken down into 83% Full Time, 13% Part Time, 1% Temporary, 2% Contract, and 1% Nights. Highlights an 93% Physical, 2% Hybrid, and 5% Remote job distribution, with an average salary of $145,969 per year, or $70.2 per hour.

Clinical Trial & Pharmacovigilance Manager

Fort Detrick, MD • On-site

VENESCO LLC
51 - 200 employees
Learn more about VENESCO LLCexternal

Full-time

Re-posted 22 days ago

Job description

Description:

 Clinical Trial & Pharmacovigilance Manager  


Venesco LLC is seeking a Clinical Trial & Pharmacovigilance Manager to lead clinical operations and drug safety surveillance activities across multiple FDA-regulated clinical development programs. This individual will provide strategic oversight for clinical trial execution, adverse event management, safety surveillance, and regulatory compliance while leading multidisciplinary teams.   


Requirements:

Duties and Responsibilities 

  • Direct Phase I and Phase II clinical trial operations. 
  • Lead pharmacovigilance and safety surveillance activities. 
  • Develop and maintain product safety profiles. 
  • Oversee adverse event collection, coding, review, and reporting. 
  • Manage DSMB activities and implementation of recommendations. 
  • Ensure compliance with FDA, ICH, and sponsor requirements. 
  • Coordinate safety reviews, risk assessments, and signal detection activities. 
  • Lead development of safety management plans and surveillance plans. 
  • Manage cross-functional teams including monitors, safety personnel, and clinical operations staff. 
  • Support INDs, Investigator Brochures, DSURs, annual reports, and safety submissions. 
  • Develop SOPs and improve operational processes. 


Minimum Qualifications 

  • Advanced degree in Clinical Research, Nursing, Pharmacy, Public Health, or Life Sciences. 
  • Minimum 10 years of clinical research experience. 
  • Demonstrated leadership of Phase I and Phase II clinical studies. 
  • Strong expertise in ICH-GCP and FDA clinical research requirements. 
  • Experience managing clinical operations and pharmacovigilance programs. 
  • Proven ability to lead multidisciplinary teams. 


Venesco, LLC, is an equal opportunity and affirmative action employer. Venesco is committed to administering all employment and personnel actions on the basis of merit and free of discrimination based on race, ethnicity, religious affiliation, gender, gender identity or expression, sexual orientation, national origin, protected veteran status, or status as an individual with a disability. Consistent with this commitment, we are dedicated to the employment and advancement of qualified minorities, women, individuals with disabilities, protected veterans, persons of all ethnic backgrounds and religions according to their abilities.

For more information on Venesco, LLC., visit https://venesco.com.