Job Title: Biochemist/Molecular Biologist Location: Cambridge, MA Type: Contract Compensation: $35-$41.82 Work Model: Onsite โ onsite Hours: 40.0 hours/week Overview Our clients BioMedicine Design (BMD) is seeking a highly motivated Biochemist/Molecular Biologist to join Biotherapeutic Expression and Purification group (BEP) in Cambridge, MA. Ideal candidates should have a strong background in molecular biology techniques and experience with nucleic acid production and analysis.
Responsibilities โข Independently execute high-throughput plasmid DNA production workflows including bacterial culture, plasmid purification, and downstream sample handling โข Operate and troubleshoot automated instrumentation including Biotage, Opentrons, and related liquid handling platforms โข Perform DNA quality control testing including gel electrophoresis, nucleic acid quantification, purity assessment, and endotoxin testing โข Prepare and submit samples for next-generation sequencing (NGS) and support basic data review of sequencing results โข Manage plasmid DNA inventory, sample storage, and tracking within electronic databases and sample management systems โข Maintain accurate records in an electronic lab notebook and ensure documentation compliance โข Collaborate with expression and purification scientists to ensure timely DNA delivery for downstream workflows โข Contribute to process improvements to enhance throughput, reproducibility, and cycle time โข Communicate progress, priorities, and risks to meet production schedules and deadlines
Requirements โข B.S. in Biological Sciences, Molecular Biology, Biotechnology, Biochemistry, or a related life sciences discipline โข 2+ years experience with molecular biology techniques including plasmid preparation, nucleic acid purification, and quantitative DNA analysis โข 2+ years experience with bacterial cell culture systems โข Proficiency in DNA QC methods including gel electrophoresis and sample preparation for sequencing โข Experience operating automated or semi-automated lab instrumentation โข Strong organizational skills with the ability to manage multiple projects in a high-throughput setting โข Proficiency with electronic lab notebooks and sample tracking systems โข Attention to detail during repetitive, high-volume tasks โข Strong communication and teamwork skills โข Commitment to laboratory safety and compliance
Preferred โข Experience with NGS library preparation or sequencing workflows โข Familiarity with Python scripting for data analysis or workflow automation โข Experience with plate-based (96/384-well) high-throughput workflows โข Familiarity with LIMS or sample management platforms (e.g., FreezerPro, Genedata)
System One, and its subsidiaries including Joulรฉ and Mountain Ltd., are leaders in delivering outsourced services and workforce solutions across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan.
System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.
Ref: #558-Scientific