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Computer Science Startup Jobs in Chicago, IL (NOW HIRING)

Tendo

Principal Data Scientist

Chicago, IL · On-site

$131.75K - $178.25K/yr

Our team-driven culture and rapid growth have earned us recognition as one of Forbes' Top Startup ... computer science, OR equivalent technical experience. * Hands-on experience writing Python code ...

blueStone

Ruby Developer

Chicago, IL · On-site

Company Description Our client is an enterprise startup that is disrupting the outdated auto ... Computer Science or equivalent years of experience 4+ years of working software development ...

Tendo

Senior Data Scientist

Chicago, IL · On-site

$110.50K - $149.50K/yr

Our team-driven culture and rapid growth have earned us recognition as one of Forbes' Top Startup ... computer science, OR equivalent technical experience. * Hands-on experience writing Python code ...

Tendo

Senior Data Scientist

Chicago, IL · On-site +1

$110.50K - $149.50K/yr

Our team-driven culture and rapid growth have earned us recognition as one of Forbes' Top Startup ... computer science, OR equivalent technical experience. * Hands-on experience writing Python code ...

Miller Cooper

QA Automation Engineer

Chicago, IL · Remote

$85K - $95K/yr

QA Automation Engineer (Playwright) Are you ready to join a cutting-edge healthcare startup ... Bachelor's degree in computer science, information technology, or related field * 3+ years QA ...

Miller Cooper

QA Automation Engineer

Chicago, IL · On-site

$85K - $95K/yr

QA Automation Engineer (Playwright) Are you ready to join a cutting-edge healthcare startup ... Bachelor's degree in computer science, information technology, or related field * 3+ years QA ...

TransMarket Group

Systems Engineer Intern

Chicago, IL

$17.25 - $22.50/hr

... also is like a startup because the potential of our group is at least one order of magnitude ... Good understanding of computer science fundamentals, including operating systems, networking, and ...

TransMarket Group

Systems Engineer Intern

Chicago, IL · On-site

$17.25 - $22.50/hr

... also is like a startup because the potential of our group is at least one order of magnitude ... Good understanding of computer science fundamentals, including operating systems, networking, and ...

griddable.io

Lead, Specialist Slack SE

Chicago, IL · On-site

Computer Science, Software Engineering, MIS • Knowledge of related applications, relational ... Griddable.io is a San Jose, CA based SaaS startup that closed Series A funding in 2017 from August ...

New

Sky9 Capital

Associate Investor

Mundelein, IL

Well-networked within the San Francisco Bay Area startup community. * Education: Bachelor's or Master's degree in Engineering, Computer Science, or a related STEM field is strictly required--we are ...

Grindr

Senior Data Scientist, Ecosystem Health

Chicago, IL · On-site

$130K - $210K/yr

... Computer Science, Statistics, Mathematics, Physics, a related quantitative field, or equivalent ... We're embedding AI into our product and operations, moving with startup speed while operating at ...

blueStone

Systems Engineer

Chicago, IL · On-site

Proven success in high-growth startup environments * Bachelor's degree or higher in Computer Science Additional Information Work with blueStone recruiting to find your next career. You can find us at ...

blueStone

DevOps Engineer

Chicago, IL · On-site

$54.25 - $74.50/hr

Proven success in high-growth startup environments * Bachelor's degree or higher in Computer Science Additional Information Work with blueStone recruiting to find your next career. You can find us at ...

G-20 Group

Junior-Mid Level Options Trader

Chicago, IL · On-site +1

The team combines a startup mindset with extensive experience in proprietary Trading, Technology ... Degree in Finance, Mathematics, Physics, Computer Science, Engineering, or a related field from a ...

G-20 Group

Junior-Mid Level Options Trader

Chicago, IL · On-site

The team combines a startup mindset with extensive experience in proprietary Trading, Technology ... Degree in Finance, Mathematics, Physics, Computer Science, Engineering, or a related field from a ...

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Computer Science Startup information

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$86K

$105.6K

$139.6K

How much do computer science startup jobs pay per year?

As of May 29, 2026, the average yearly pay for computer science startup in Chicago, IL is $105,589.00, according to ZipRecruiter salary data. Most workers in this role earn between $92,700.00 and $118,500.00 per year, depending on experience, location, and employer.

What is a Computer Science Startup job?

A Computer Science Startup job typically involves working in a newly founded tech company, focusing on developing innovative software, algorithms, or systems. Employees in these roles often wear multiple hats, including coding, product development, and problem-solving. Startups require adaptability, creativity, and a willingness to work in a fast-paced, evolving environment. Unlike established companies, startups may offer more autonomy and opportunities for rapid career growth but can also come with higher uncertainty.

What are the key skills and qualifications needed to thrive in the Computer Science Startup position, and why are they important?

To succeed in founding or leading a computer science startup, you need a solid background in computer science or software engineering, an entrepreneurial mindset, and experience in product development. Familiarity with programming languages, cloud platforms, and agile development tools, as well as knowledge of industry certifications like AWS Certified Developer or ScrumMaster, can be highly beneficial. Strong skills in communication, problem-solving, adaptability, and leadership are crucial to navigate uncertainties and drive team collaboration. These skills and qualities are vital to innovate effectively, secure investment, and build scalable tech solutions in a highly competitive market.

What are the typical challenges faced in a computer science startup and how can I prepare for them?

Working in a computer science startup often involves managing rapid changes in technology, tight deadlines, and the pressure to deliver innovative solutions with limited resources. Team members frequently wear multiple hats, balancing development, testing, and sometimes even customer support or business planning. To prepare, it’s helpful to stay up-to-date with industry trends, cultivate flexibility in your work style, and strengthen your project management skills. Building a strong network and seeking mentorship within the startup and tech communities can also provide practical support and guidance. Embracing a proactive, problem-solving approach will help you navigate and thrive in this dynamic environment.
More about Computer Science Startup jobs
What are the most commonly searched types of Computer Science Startup jobs in Chicago, IL? The most popular types of Computer Science Startup jobs in Chicago, IL are:
What are popular job titles related to Computer Science Startup jobs in Chicago, IL? For Computer Science Startup jobs in Chicago, IL, the most frequently searched job titles are:
What job categories do people searching Computer Science Startup jobs in Chicago, IL look for? The top searched job categories for Computer Science Startup jobs in Chicago, IL are:
Computer Science Startup jobs near you
Infographic showing various Computer Science Startup job openings in Chicago, IL as of May 2026, with employment types broken down into 91% Full Time, and 9% Nights. Highlights an 91% In-person, and 9% Remote job distribution, with an average salary of $105,589 per year, or $50.8 per hour.
Principal Data Scientist

Principal Data Scientist

Tendo

Chicago, IL • On-site

$131.75K - $178.25K/yr

Full-time

Medical, Dental, Vision, Life, Retirement

Posted 3 days ago

Job description

The Principal Data Scientist will support Tendo analytics projects focused on quality management and risk adjustment. The person in this role will access data from multiple sources (public and private) and translate it into information that is meaningful and actionable for health systems. The Principal Data Scientist develops, maintains, and enhances predictive models that improve products in several areas including, but not limited to quality, risk, and operational efficiency. We're looking for someone who brings an AI-native mindset, has hands-on experience applying AI or machine learning to real-world problems, and is passionate about exploring how emerging AI capabilities can improve healthcare delivery and outcomes. In addition, the Principal Data Scientist will also have the opportunity to ask novel, data-driven questions and drive new analyses.

About Tendo
Make an impact-join our team!

We're a fast-growing, mission-driven company building a culture that enables teams and individuals to thrive. Our team-driven culture and rapid growth have earned us recognition as one of Forbes' Top Startup Employers for both 2024 and 2025. Led by an experienced and proven team, we live by our values and are always on the hunt for motivated people with diverse experiences and backgrounds to help us improve the care journey for patients, clinicians, and caregivers by creating software that provides seamless, intuitive, and user-friendly experiences. 

If you like working with innovative technologies and want to be part of a growing team that will help transform the healthcare experience, we encourage you to apply today!

Job Location
Tendo has hubs in San Francisco, CA; San Diego, CA; Salt Lake City, UT; Chicago, IL; Nashville, TN; and Philadelphia, PA. Candidates may be located in any one of our hub locations.
Responsibilities
  • Analyze data from multiple databases to drive optimization and improvement of quality outcomes, resource utilization, and risk adjustment.
  • Develop custom data models and algorithms to apply to data sets.
  • Use predictive modeling to increase and optimize patient outcomes, patient experiences, risk adjustment opportunities, and other business outcomes.
  • Explore and experiment with emerging AI technologies to evaluate their applicability in solving healthcare problems and improving operational workflows.
  • Develop analytic data sets and use statistical software to analyze data sets as requested.
  • Use third party software tools in the development of queries and visualizations.
  • Coordinate with different functional teams to implement models and monitor outcomes.
Requirements
  • Bachelor's degree in data science, statistics, epidemiology, engineering, information science, computer science, OR equivalent technical experience. 
  • Hands-on experience writing Python code including, but not limited to, machine learning, data science and engineering, and ETL pipelines. 
  • 7+ years of experience in data analysis software, with data science experience preferred.
  • 7+ years of experience with GitHub/Git, Python, SQL, statistics, and ML modeling.
  • Track record of applying AI or ML models to solve practical, real-world problems-ideally in healthcare or similar complex domains.
  • Knowledge of statistical concepts and data mining methods such as: Hypothesis testing (or A/B testing), distribution analysis, Bayesian estimation, Linear and Logistic Regression, GLMs, text mining, time series analysis, etc.
  • Knowledge of a variety of traditional machine learning techniques such as: feature engineering methods for large scale numerical and categorical data, dimensionality reduction, clustering, Decision Trees/Random Forests/Gradient Boosted Decision Trees, Deep Learning.
  • Knowledge of machine learning implementation strategies such as: proper and thorough evaluation of ML models in production, detecting data/covariate/concept drift, leveraging feature stores and model registries, deploying models as REST APIs, integrating models into products, etc.
  • Interest in staying current on AI advancements (e.g., generative AI, LLMs, foundation models), and enthusiasm for integrating new capabilities into analytical workflows.
  • Demonstrated proficiency in writing SQL queries on large, complex datasets for data analysis and analytics engineering.
  • Strong problem-solving skills with an emphasis on data analytics.  
  • Excellent written and verbal communication skills for coordinating across teams.
Nice to Have
  • Experience in the healthcare setting preferred.
  • Experience with Epic EMR data preferred, but not required.
  • Experience with healthcare financials/claims preferred, but not required.

Base Salary Range
$131,750-$178,250

This salary range is offered with the understanding that final compensation is based on a number of factors including geography and experience. Tendo also offers an equity package, annual bonuses, and benefits.

Benefits
For full time employees, Tendo also offers full health benefits (medical, dental, and vision), flexible spending and health savings accounts, company paid life insurance, company paid short-term and long-term disability, company equity, voluntary benefits, 401(k), company paid holidays, flexible time off, and an employee wellness program  ("Breathe").
Tendo is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, sex, sexual orientation, gender identity or expression, religion, national origin or ancestry, age, disability, marital status, pregnancy, protected veteran status, protected genetic information, political affiliation, or any other characteristics protected by local laws, regulations, or ordinances.
We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.
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