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Computational Engineering Jobs in California (NOW HIRING)

Onebridge

Computational Biology MLOps Engineer

San Diego, CA · On-site

$118K - $139K/yr

... engineering. Since 2000, we have partnered with some of the largest healthcare, life sciences ... Computational Biology MLOps Engineer | About You As a Computational Biology MLOps Engineer, you are ...

Onebridge

Computational Biology MLOps Engineer

San Diego, CA · On-site +1

$118K - $139K/yr

... engineering. Since 2000, we have partnered with some of the largest healthcare, life sciences ... Computational Biology MLOps Engineer | About You As a Computational Biology MLOps Engineer, you are ...

Onebridge

Computational Biology MLOps Engineer

San Diego, CA

$118K - $139K/yr

... engineering. Since 2000, we have partnered with some of the largest healthcare, life sciences ... Computational Biology MLOps Engineer | About You As a Computational Biology MLOps Engineer, you are ...

LLNL

Senior Mechanical Engineering Analyst

Livermore, CA · On-site

$210K - $267K/yr

You will develop computational models using custom, in-house codes, conduct engineering analysis of full weapon systems and components in thermal, quasi-static, dynamic, and hydrodynamic environments ...

LLNL

Senior Mechanical Engineering Analyst

Livermore, CA · On-site

$9.7K/wk

You will develop computational models using custom, in-house codes, conduct engineering analysis of full weapon systems and components in thermal, quasi-static, dynamic, and hydrodynamic environments ...

LLNL

Senior Mechanical Engineering Analyst

Livermore, CA · On-site

$210K - $267K/yr

You will develop computational models using custom, in-house codes, conduct engineering analysis of full weapon systems and components in thermal, quasi-static, dynamic, and hydrodynamic environments ...

LLNL

Microwave/RF Engineer

Livermore, CA · On-site

$9.7K/wk

These positions are in the Computational Electromagnetics Group of the Computational Engineering Division (CED), within the Engineering Directorate. Depending on your assignment, these positions may ...

Tamarind Bio

Computational Scientist

San Francisco, CA · On-site

They are seeking a Computational Scientist to curate and scale their library of AI tools, working ... Responsibilities : • Work with founders and engineers to integrate and deploy biological ML ...

LLNL

Microwave/RF Engineer

Livermore, CA · On-site

These positions are in the Computational Electromagnetics Group ofthe Computational Engineering Division (CED), within the Engineering Directorate. Depending on your assignment, these positions may ...

LLNL

Microwave/RF Engineer

Livermore, CA

These positions are in the Computational Electromagnetics Group of the Computational Engineering Division (CED), within the Engineering Directorate. Depending on your assignment, these positions may ...

Mango Inc

Computational Imaging Engineer

Los Angeles, CA · On-site

$120K - $141K/yr

They are seeking a Computational Imaging Engineer to take technical ownership of their optical systems and imaging pipeline, collaborating across multiple teams to develop innovative imaging ...

LLNL

Machine Learning (ML) Bioengineer

Livermore, CA

This position will be in the Computational Engineering Division (CED), within the Engineering Directorate, matrixed to the Bioresilience Incubator. As a member of our multidisciplinary team, you will ...

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Computational Engineering information

See California salary details

$47.9K

$119.9K

$135.7K

How much do computational engineering jobs pay per year?

As of Aug 7, 2026, the average yearly pay for computational engineering in California is $119,924.00, according to ZipRecruiter salary data. Most workers in this role earn between $110,000.00 and $129,800.00 per year, depending on experience, location, and employer.

What skills and qualifications are needed to thrive as a computational engineer?

To thrive as a Computational Engineer, a strong background in mathematics, computer science, and engineering fundamentals is essential, generally supported by a degree in computational engineering or a related field. Familiarity with programming languages like Python, MATLAB, or C++, as well as experience using simulation software and high-performance computing systems, is typically required. Analytical thinking, effective communication, and problem-solving abilities are important soft skills for collaboration and innovation. These competencies enable Computational Engineers to develop accurate models, optimize complex systems, and deliver efficient solutions in multidisciplinary environments.

What does a computational engineer do?

A computational engineer develops and applies mathematical models, algorithms, and simulations to solve complex engineering problems. They often use programming languages and software tools to analyze data, optimize systems, and improve designs in fields such as aerospace, automotive, or energy. Strong skills in programming, numerical methods, and problem-solving are essential for this role.

Is computational engineering in demand?

Computational engineering is in high demand across industries such as aerospace, automotive, and energy, where advanced simulations and modeling are essential. Professionals with skills in programming, numerical methods, and software tools like MATLAB or Python are sought after for their ability to optimize designs and solve complex problems.

What are some common challenges computational engineers face in their work?

Computational Engineers often encounter complex, large-scale problems that require developing accurate and efficient computational models, which can be challenging due to intricacies in physical systems or computational resource limitations. Managing tight project deadlines while ensuring high-quality results and adapting to rapidly evolving technology are also common aspects of the role. Collaboration across multidisciplinary teams—often with scientists, designers, or other engineers—requires strong communication and adaptability. Embracing these challenges can help Computational Engineers expand their expertise and positively impact project outcomes.

What is a computational engineer?

A Computational Engineering job involves using mathematical models, algorithms, and computer simulations to analyze and solve engineering problems. It combines principles from computer science, applied mathematics, and engineering to improve product design, optimize systems, and enhance efficiency in various industries. Professionals in this field develop software tools, conduct simulations, and utilize high-performance computing to solve complex engineering challenges in areas such as aerospace, automotive, energy, and healthcare.

What are the most commonly searched types of Computational Engineering jobs in California? The most popular types of Computational Engineering jobs in California are:
What are popular job titles related to Computational Engineering jobs in California? For Computational Engineering jobs in California, the most frequently searched job titles are:
What job categories do people searching Computational Engineering jobs in California look for? The top searched job categories for Computational Engineering jobs in California are:
Computational Engineering jobs near you
Infographic showing various Computational Engineering job openings in California as of August 2026, with employment types broken down into 90% Full Time, 5% Part Time, 4% Contract, and 1% Nights. Highlights an 86% Physical, 4% Hybrid, and 10% Remote job distribution, with an average salary of $119,924 per year, or $57.7 per hour.

Research Associate/Senior Research Associate

Shennon Biotechnologies

San Francisco, CA

Full-time

Medical, Dental, Vision, Life, Retirement

Re-posted 22 days ago

Job description

We are a well-funded biotech company that is redefining drug discovery and development through our fully integrated platform. We combine ultra-high-throughput microfluidics driven functional screening, computational engineering, and translational immunology into a unified engine. Rather than approaching drug development as a series of disconnected steps, we seamlessly integrate the discovery of novel targets, functional screening of binders, computational optimization, and predictive safety assessment to develop more better and safer therapeutics. This end-to-end approach enables faster iteration, deeper biological insight, and the development of better drugs with greater precision and confidence.

We are currently looking for a research associate to join our interdisciplinary team. The candidate is expected to adapt quickly and communicate well, especially in a fast-paced startup environment. We pay competitive salaries with bonus and equity, plus full benefits that include medical, dental, vision, 401k match, commuter benefits and daily lunch.

Responsibilities:

  • Carry out a variety of cell biology tasks, including mammalian cell culture, virus harvesting, and transfections/transduction of various cell lines.
  • Isolate and engineer primary T cells using different techniques.
  • Perform functional assays to evaluate T cell responses.
  • Assist with molecular cloning tasks including design, PCR, gel extraction, transformation, plasmid preparation, and sequence analysis.
  • Collaborate with team on other experiments when needed.

Qualifications:

  • Bachelor's degree in Molecular Biology, Cell Biology, Biochemistry, Biomedical Engineering or equivalent.
  • Skill sets required: molecular cloning, flow cytometry, ELISA, cell line and primary T cell culture, and lentiviral transduction.
  • 2+ years of industry experience.
  • Responsible, accountable, and detail-oriented
  • Detail oriented, excellent organization skills and communication skills.

Nice to haves: 

  • Understanding of T cell immunology.
  • Experience with TCE development.
  • Experience with NGS sequencing and analysis.

Shennon Bio is an equal opportunity employer, and we welcome applicants from diverse backgrounds to apply.

Job Type: Full-time, Mon-Fri

Benefits: Daily lunch + Commuter benefits + Health insurance (Medical, Dental and Vision, 100% premium covered for Gold plan) + life insurance, flexible time off and sick leave, unlimited healthy snacks and drinks.

Company Culture: Collaboration, Ownership and Authenticity.

Apply