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Clinical Trial Lab Manager Jobs (NOW HIRING)

ProPharma Group

## EDC Clinical Trial DesignerApplylocations: United Statestime type: Full timeposted on: Posted ... lab management, coding functionality. + Input into design of post-production form changes to the ...

Clinovo

Clinical Trial Manager

Waltham, MA · On-site

The Role The Clinical Trial Manager (CTM) will be a key contributor to the successful execution of clinical trials and will play an important role in building and maintaining relationships with ...

Prometrika LLC

Clinical Trial Associate II

Cambridge, MA · On-site

$75K - $90K/yr

The Clinical Trial Associate II (CTA II) supports, coordinates, and implements clinical research ... lab supplies, etc.) * With minimal oversight, manage clinical operations site payments, prepare ...

Icon plc

Clinical Trial Manager

Blue Bell, PA · On-site

As a Clinical Trial Manager at ICON, you will manage clinical trial operations activities, supporting your team and stakeholders to deliver high-quality outcomes across our clinical programmes. What ...

VENESCO, LLC

Clinical Trial Manager

Fort Detrick, MD · On-site

$125K - $143K/yr

Description Clinical Trial Manager Venesco LLC is seeking Clinical Trial Managers to provide leadership and operational oversight for FDA-regulated clinical studies, ensuring studies are executed in ...

CareDx, Inc.

Clinical Trial Manager

Brisbane, CA · Remote

The Clinical Trial Manager (CTM) is responsible for the management of clinical trials from study ... lab test requisitions, etc.), plans and managing study-specific meetings (e.g. Study Team Meetings ...

CareDx, Inc.

Clinical Trial Manager

Brisbane, CA · On-site

The Clinical Trial Manager (CTM) is responsible for the management of clinical trials from study ... lab test requisitions, etc.), plans and managing study-specific meetings (e.g. Study Team Meetings ...

Kardigan

Clinical Trial Manager

Princeton, NJ · On-site

As a Clinical Trial Manager (CTM), you will be part of the Clinical Operations team reporting to the asset's Clinical Trial or Clinical Program Lead. This position will be responsible for the ...

Genesis10

Clinical Trial Budget Manager

Ridgefield, CT · On-site

$57.14/hr

The Clinical Trial Budget Manager is responsible for ensuring that clinical trial site budgets are ... AGW delivers operational, clinical, lab and professional talent with a strong focus on healthcare ...

Venesco LLC

Clinical Trial Manager

Fort Detrick, MD · On-site

$125K - $143K/yr

Clinical Trial Manager Venesco LLC is seeking Clinical Trial Managers to provide leadership and operational oversight for FDA-regulated clinical studies, ensuring studies are executed in accordance ...

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Clinical Trial Lab Manager information

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How much do clinical trial lab manager jobs pay per hour?

As of Sep 11, 2026, the average hourly pay for clinical trial lab manager in the United States is $62.52, according to ZipRecruiter salary data. Most workers in this role earn between $50.72 and $70.43 per hour, depending on experience, location, and employer.

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For Clinical Trial Lab Manager jobs, the most frequently searched job titles are:

Infographic showing various Clinical Trial Lab Manager job openings in the United States as of August 2026, with employment types broken down into 88% Full Time, 11% Part Time, and 1% Contract. Highlights an 85% Physical, 2% Hybrid, and 13% Remote job distribution, with an average salary of $130,034 per year, or $62.5 per hour.

Clinical Trial Manager

Cambridge, MA • On-site

Repertoire Immune Medicines
Biotechnology Research and Development • 51 - 200 employees
Learn more about Repertoire Immune Medicinesexternal

Full-time

Medical, Dental, Vision, Life, Retirement

Posted 14 days ago

Key responsibilities

  • Manage all aspects of early-stage oncology clinical trials from start-up to close-out, ensuring timely, budget-compliant, and regulatory-compliant execution.

  • Oversee outsourced activities with CROs and vendors, including performance oversight, compliance monitoring, and review of monitoring reports.

  • Monitor trial progress, including participant enrollment, data review, sample collection, and provide regular status updates.

Job description

Company Overview
Repertoire Immune Medicines is a clinical-stage biotechnology company harnessing the power of the human immune system to develop transformative therapies for cancer and autoimmune disease. Using its proprietary DECODE™ platform—which maps the immune synapse between T cell receptors (TCRs) and their antigen targets—Repertoire translates unique biological insights into potent and targeted off-the shelf immune medicines. The company integrates deep protein engineering expertise with artificial intelligence, powered by a proprietary DECODE database of over one billion TCR-antigen interactions, to accelerate discovery and optimize drug candidates.
From its sites in Cambridge, Massachusetts and Zurich, Switzerland, Repertoire is advancing a pipeline of T cell-targeted immunotherapies with the potential to address a broad range of cancers and autoimmune disorders. The company’s lead oncology program, RPTR-1-201, a TCR bispecific, has initiated a Phase 1/2 clinical trial across multiple solid tumor indications. Repertoire plans to advance additional TCR bispecific therapies into clinical trials over the next 12-18 months. In autoimmune disease, Repertoire is partnering with leading pharmaceutical companies to develop mRNA tolerizing therapies designed to selectively expand regulatory T cells and reset the immune system.
Repertoire was founded in 2019 by Flagship Pioneering and is supported by a strong investor base. The DECODE platform has been validated through four strategic partnerships with leading pharmaceutical companies—Bristol Myers Squibb, Genentech, Eli Lilly, and Pfizer—representing over $4.5 billion in disclosed total deal value and $185 million in upfront payments received to date.
 
Clinical Trial Manager

Role Overview
We are seeking an experienced Clinical Trial Manager to provide both strategic leadership and hands-on oversight of early-stage oncology trials, including first-in-human trials. Reporting to the Director of Clinical Operations, you will oversee all aspects of trial management -from start-up through close-out - ensuring trials are delivered on time, on budget, and fully compliant with regulatory and quality standards. As the primary point of contact for cross-functional teams, CROs, vendors, and investigative sites, you will provide strategic guidance, operational oversight, and proactive risk management.
This is a hands-on role in a fast-paced, collaborative environment, offering the opportunity to directly influence the advancement of innovative therapies for patients.
Key Responsibilities
  • Work with a cross-functional trial teams to manage all aspects of clinical trials ensuring trials are executed on time, on budget, and in compliance with SOPs, ICH/GCP, and regulatory requirements.
  • Identify and anticipate trial issues or risks that may impact budget, resources, and timelines; plan mitigation strategies with the cross-functional team and escalates as necessary.  
  • Manage outsourced activities with CROs and vendors (e.g., biomarker and specialty labs), including oversight of performance, compliance with ICH/GCP and SOPs, development of oversight plans, and review of monitoring reports to maintain trial quality and compliance.
  • Manage trial budgets and contracts, including forecasting, invoice review, and expense tracking for accurate reporting.
  • Monitor trial progress, including participant enrollment, clinical data review, sample collection, and adherence to timelines; provide regular trial status updates and metrics.
  • Guide trial teams and investigator sites to ensure consistent interpretation and execution of trial protocols and procedures.
  • Contribute to the development and review of trial-related documents (protocols, ICFs, clinical trial plans, CRFs, manuals, reports, and regulatory documentation).
  • Ensure Trial Master File (TMF) completeness, accuracy, and inspection readiness, whether managed internally or outsourced.
  • Participate in the development and refinement of departmental SOPs, processes, and best practices.
Qualifications/Experience
  • Bachelor’s degree in Life Sciences or related field (advanced degree preferred) with 3+ years of clinical trial management experience.
  • Proven track record in CRO and vendor management, including oversight of performance, issue resolution, and budget management.
  • Ability to lead trials independently, ideally within a small, fast-paced team environment.
  • Working knowledge of data management, biostatistics, and pharmacovigilance.
  • Global trial experience, including management of multi-country trials from start-up through close-out.
  • Thorough understanding of FDA regulations and ICH GCP guidelines.
  • Proficiency with clinical trial systems (EDC, CTMS, TMF) and expertise in trial master file organization and regulatory documentation.
  • On-site monitoring experience (preferred).
  • Excellent communication skills, with the ability to collaborate effectively across teams.
  • Highly organized with strong problem-solving, critical thinking, and prioritization skills.
  • Ability to travel domestically and internationally, up to 20%.
The base salary for this role ranges from $112,000 to $160,000 and is determined based on a candidate’s skills, experience, and internal equity. In addition to a competitive base salary, Repertoire offers a broad range of benefits designed to attract, retain, and motivate top talent, including medical, dental, vision, and life insurance, flexible time off, a 401(k) retirement plan, and short- and long-term incentive opportunities. Compensation and benefits are based on Repertoire’s good faith estimate at the time of publication and may be updated in the future.
Repertoire is committed to social responsibility and to developing an inclusive culture. Much as the power of the immune system lies in the diversity of T and B cells, our work requires the creativity and ingenuity of a diverse workforce.  We believe in actively pursuing equity in all facets of the work experience at Repertoire.  We will continue to educate ourselves about the inequities and barriers present in our society and take action as a company where we can make a difference.
Repertoire is proud to be an Equal Opportunity Employer.

Recruitment & Staffing Agencies: Repertoire Immune Medicines (“Repertoire”) does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Repertoire or its employees is strictly prohibited unless contacted directly by Repertoire’s internal Human Resources team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Repertoire, and Repertoire will not owe any referral or other fees with respect thereto.

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