Clinical Research Program Manager Jobs in Raleigh, NC

School of Medicine:

Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine along with the Duke University School of Nursing, and Duke University Health System comprise Duke Health, a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations.

Be You.

The Duke Cancer Institute (DCI) is seeking a Clinical Research Coordinator to play a critical, hands-on role in supporting an operationally complex research study within the Cancer Control and Population Sciences Clinical Research Program (CCPS). This position is housed within the Oncology Clinical Research Unit (CRU) and supports high-impact cancer research that directly engages adult participants through electronic consent, surveys, and biospecimen collection.

In this role, you will provide leadership and coordination across all phases of study operations-recruitment, participant engagement, regulatory compliance, data integrity, and collaboration with investigators and sponsors. You will be deeply involved in day-to-day study execution while also helping identify process improvements and resolving operational challenges. If you enjoy balancing detailed coordination work with meaningful participant interaction and collaborative teamwork, this role offers an opportunity to make a direct impact on cancer research at Duke.

Minimum Requirements

• Completion of an Associate's degree
• Two years of relevant research experience
• Completion of the DOCR North Carolina state-approved Clinical Research Apprenticeship program may substitute for one year of experience
• Ability to effectively use standard computing software and web-based applications (e.g., Microsoft Office products and internet browsers)

Preferred Qualifications

• Experience with human subjects research, including informed consent, confidentiality, and adherence to IRB-approved protocols
• Strong participant-facing communication skills, including conducting outreach and follow-up via phone and email using standardized scripts
• Experience managing complex operational tracking workflows, including monitoring participant status across multiple study pathways
• Advanced knowledge or experience building and maintaining databases using REDCap or similar data capture systems
• Familiarity with clinical research management systems such as OnCore, eREG, Epic/EMR, or other EDC platforms

Other Requirements

• Ability to meet and maintain Duke and project-specific training and certification requirements

Be Bold.

• Coordinate and manage study operations by implementing recruitment and retention strategies, evaluating enrollment feasibility, maintaining participant engagement, and identifying barriers to participation while proposing and implementing solutions across the study lifecycle.
• Recruit, screen, consent, and support participants by working closely with the Principal Investigator and study team; independently conduct and document consent, schedule and conduct study visits, manage repeated participant outreach and follow-up, and ensure accurate tracking of participant progress across multiple participation pathways.
• Ensure regulatory compliance and study integrity by maintaining regulatory binders, enrollment logs, and system documentation; recording and promptly reporting adverse events; assisting with Delegation of Authority Logs, COI documentation, Data Safety Monitoring Plans, and Duke Research Data Lifecycle requirements.
• Manage and protect study data by accurately entering data into EDC systems, identifying and resolving data discrepancies, investigating missing or incomplete documentation, and ensuring compliance with institutional policies related to data security, provenance, and confidentiality.
• Serve as a key communication and leadership resource by acting as the primary liaison among sponsors, investigators, and study personnel; escalating issues appropriately; supporting onboarding and training of research staff; sharing research updates; and contributing to continuous improvement of research processes.

Choose Duke.

Duke University and the Duke Cancer Institute offer an unparalleled environment for advancing clinical and population-based cancer research. CCPS conducts innovative studies designed to improve cancer prevention, early detection, and survivorship outcomes, and this role directly supports that mission through hands-on coordination of a complex, high-visibility research program.

This position will support the YOGI Study, a cutting-edge research initiative focused on gastrointestinal health and young-onset colorectal cancer. The study's multi-pathway design, evolving IRB activity, repeated participant engagement, and biospecimen collection create a dynamic learning environment where your organizational skills, problem-solving abilities, and research expertise will be fully utilized and continuously developed.