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Clinical Monitoring Jobs in Illinois (NOW HIRING)

Apex Systems

Pharmacist (URGENT)

Northbrook, IL

$59 - $71/hr

Prior experience with clinical monitoring and management of patients, pumps, knowledge of IV supplies Duties: Pharmacy knowledge; Microsoft Office literacy; Excellent oral and written communication ...

ICON

Senior Clinical Research Associate

Chicago, IL · On-site +1

$110K - $138K/yr

Implements and monitors clinical trials to ensure sponsor and investigator obligations are being met and are compliant with applicable local regulatory requirements and Internation Conference on ...

Icon plc

Senior Clinical Research Associate

Chicago, IL · On-site

$110K - $138K/yr

Implements and monitors clinical trials to ensure sponsor and investigator obligations are being met and are compliant with applicable local regulatory requirements and Internation Conference on ...

CellCarta

Clinical Study Specialist I

Naperville, IL · On-site

$55K - $73K/yr

Clinical Study Specialist I Are you a clinical operations professional who thrives on precision ... Monitoring Oversight & Action Item Management: Review third-party monitoring visit reports, log ...

CellCarta

Clinical Study Specialist I

Naperville, IL · On-site

Clinical Study Specialist I Are you a clinical operations professional who thrives on precision ... Monitoring Oversight & Action Item Management: Review third-party monitoring visit reports, log ...

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Clinical Monitoring information

See Illinois salary details

$11

$39

$67

How much do clinical monitoring jobs pay per hour?

As of Sep 2, 2026, the average hourly pay for clinical monitoring in Illinois is $39.85, according to ZipRecruiter salary data. Most workers in this role earn between $27.93 and $51.01 per hour, depending on experience, location, and employer.

What is clinical monitoring?

Clinical monitoring is the process of overseeing clinical trials to ensure they are conducted, recorded, and reported in accordance with the protocol, standard operating procedures, Good Clinical Practice (GCP), and regulatory requirements. Clinical monitors, often called Clinical Research Associates (CRAs), are responsible for checking the progress of a clinical trial at research sites, verifying data accuracy, ensuring participant safety, and ensuring compliance with regulations. Their work is essential in maintaining the integrity of clinical data and the safety of trial participants.

What are the key skills and qualifications needed to thrive in clinical monitoring, and why are they important?

To thrive in Clinical Monitoring, you need a solid background in life sciences or nursing, strong knowledge of clinical trial protocols, and often a relevant degree such as a BS in a scientific field. Familiarity with electronic data capture (EDC) systems, Good Clinical Practice (GCP) guidelines, and certifications like ACRP or SOCRA are highly valued. Exceptional attention to detail, strong organizational skills, and effective communication are crucial soft skills for managing trial sites and ensuring compliance. These competencies are vital for ensuring data integrity, regulatory adherence, and the smooth progress of clinical trials.

What are some common challenges faced by professionals in clinical monitoring, and how can they be addressed?

Clinical Monitoring professionals often encounter challenges such as managing multiple study sites, ensuring protocol compliance, and maintaining clear communication with site staff. Navigating regulatory requirements and handling unexpected issues, like protocol deviations or data discrepancies, can also be demanding. To address these, strong organizational skills, proactive communication, and thorough documentation are essential. Building collaborative relationships with site personnel and staying updated on regulatory guidelines can help ensure smoother study progress and data integrity.

What is the difference between Clinical Monitoring vs Clinical Data Management?

AspectClinical MonitoringClinical Data Management
Primary RoleOversees site activities, ensures protocol adherence, monitors patient safetyCollects, validates, and manages clinical trial data
Required CredentialsTypically a degree in life sciences, nursing, or related field; often requires monitoring certificationsDegree in life sciences, biostatistics, or related; data management certifications beneficial
Work EnvironmentOn-site at clinical trial sites or remotely, interacting with site staffPrimarily office-based, working with electronic data capture systems
Industry UsageCommonly used in clinical trial phases, especially during site visitsUsed throughout the trial for data collection, cleaning, and analysis

Clinical Monitoring focuses on overseeing clinical trial sites and ensuring compliance, while Clinical Data Management handles the collection and validation of trial data. Both roles are essential in clinical research, often working closely but with distinct responsibilities.

What are the most commonly searched types of Clinical Monitoring jobs in Illinois?

The most popular types of Clinical Monitoring jobs in Illinois are:

What are popular job titles related to Clinical Monitoring jobs in Illinois?

For Clinical Monitoring jobs in Illinois, the most frequently searched job titles are:

What job categories do people searching Clinical Monitoring jobs in Illinois look for?

The top searched job categories for Clinical Monitoring jobs in Illinois are:

What cities in Illinois are hiring for Clinical Monitoring jobs?

Cities in Illinois with the most Clinical Monitoring job openings:

Clinical Monitoring jobs near you
Infographic showing various Clinical Monitoring job openings in Illinois as of August 2026, with employment types broken down into 2% As Needed, 58% Full Time, 34% Part Time, and 6% Contract. Highlights an 95% Physical, 1% Hybrid, and 4% Remote job distribution, with an average salary of $82,892 per year, or $39.9 per hour.

Senior Clinical Line Manager

ProPharma Group

Western Springs, IL • On-site

Full-time

Re-posted 7 hours ago

Job description

For the past 25 years, ProPharma has improved the health and wellness of patients by providing advice and expertise that empowers biotech, med device, and pharmaceutical organizations of all sizes to confidently advance scientific breakthroughs and introduce new therapies. ProPharma partners with its clients through an advise-build-operate model across the complete product lifecycle. With deep domain expertise in regulatory sciences, clinical research solutions, quality & compliance, pharmacovigilance, medical information, and R&D technology, ProPharma offers an end-to-end suite of fully customizable consulting solutions that de-risk and accelerate our partners' most high-profile drug and device programs.
Essential Functions:
  • Provides support to study teams in resourcing CRAs and other clinical operations staff, as appropriate, for planned and ongoing clinical trials.
  • Supervises and assists with clinical monitoring study teams' assignments and workload.
  • Monitors performance of CRAs and other clinical operations staff, as appropriate, on a continuous basis including, but not limited to, clinical monitoring plan compliance, trip report turnaround metrics, quality of the trip report, action item management, query management, data currency, and TMF management.
  • Manages site trends through dashboard review and ongoing risk assessment to ensure quality standards and address concerns associated with study delivery at sites.
  • May conduct, attend, or support co-monitoring visits and/or other training, as needed or as necessary to evaluate CRAs.
  • May be assigned to study team or other projects based on program/company needs.
  • Assists with the development of study/program plans, (e.g., Monitoring Plan, eCRF Completion Guidelines, etc.) as needed.
  • Implements individual development and provides coaching and mentoring to monitoring personnel.
  • Lead and author training programs for monitoring operations teams.
  • Proposes proactive, innovative ideas to help resolve challenges faced by the monitoring teams.
  • Establishes regular lines of communication with Clinical Leads, Project Managers, and additional internal and external stakeholders to manage CRA clinical delivery and report/escalate issues to Clinical Operations.
  • Assures monitoring teams are performing activities in compliance with good clinical practices (GCP) and in accordance with the regulatory agency requirements, and ICH guidelines.
  • Assumes leadership role to ensure the monitoring of clinical operations milestones and timelines are achieved.
  • Compiles and reports KPIs across all site monitoring CRA teams, drives insights that lead to overall improvement in business results. .
  • Performs oversight visits of CRAs.
  • In conjunction with the Clinical Operations leadership, leads monitoring operations, quality, and process improvement initiatives as assigned.
  • Manage/mentor and develop junior staff.
  • Demonstrated experience in change management initiatives
  • Other duties as assigned.

Necessary Skills and Abilities:
  • Excellent verbal and written communication skills; interpersonal and presentation skills are required.
  • Extensive understanding of SOPs, Work Instructions, regional and global regulations, ICH Guidelines, and GCPs governing the conduct of clinical trials.
  • Effective communication, interpersonal, and leadership skills with the ability to partner with cross functional internal and external stakeholders.
  • Must be able to prioritize multiple tasks, plan proactively, and accomplish goals using work instructions and procedures.
  • Ability to develop tools and processes that increase measured efficiencies of the project.
  • Must be able to anticipate obstacles and proactively develop solutions to achieve project goals.
  • Must be able to compile and report individual and team KPIs.

Educational Requirements:
  • Bachelor's degree required, preferably in life sciences, nursing, or a related discipline.

Experience Requirements:
  • Minimum 10 years of experience working in clinical research. Minimum 5 years of experience in a monitoring leadership capacity including direct report management
  • Experience using Microsoft Office (Word, Excel, Power Point) applications to prepare charts, tables, forms, reports, and presentations.
  • Experience working in CTMS, EDC, IVRS, and eTMF systems.
  • Experience managing/mentoring and developing junior staff.
  • Demonstrated experience in change management initiatives.

#LI-REMOTE #LI-JH1
We celebrate our differences and strive to create a workplace where each person can be their authentic self. We are committed to diversity, equity, and inclusion. Employees are encouraged to unleash their innovative, collaborative, and entrepreneurial spirits. With a holistic approach as an Equal Opportunity Employer, we provide a safe space where all employees feel empowered to succeed.
All applications to roles at ProPharma are personally reviewed by a member of our recruitment team. We do not rely on AI screening tools to support our hiring process. You will always receive an outcome to your application so that you have an answer from us - whether you're successful or not.
Whilst ProPharma supports remote working, we also recognise the value that comes from in person collaboration. As such, we encourage any new hires that are based within a reasonably short commute of one of our offices to work on a hybrid basis and spend some time working from that office location, as agreed with your manager. All applications will be treated on their own merit and candidates will not be at any advantage or disadvantage based on their proximity to an office.
***ProPharma Group does not accept unsolicited resumes from recruiters/third parties. Please, no phone calls or emails to anyone regarding this posting.***

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