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Clinical Genomic Variant Scientist Jobs (NOW HIRING)

Belay Diagnostics

Clinical Genomics Analyst

Chicago, IL · On-site

$80K - $90K/yr

Evaluate variant function, potential clinical impact and genotype-phenotype relationships using scientific literature and available genomic tools * Write clear, communicable reports based on test ...

Baylor Genetics

Clinical Genomics Scientist III- WGS

The Clinical Genomic Scientist II demonstrates a strong understanding of the principles of variant ... curation and genetic data analysis. * Relevant experience: 2-4 years * Certification (optional): MB ...

Ambry Genetics

$110K - $114K/yr

The Clinical Genomic Scientist II is highly proficient in variant classification guidelines and in following report generation protocols to meet requirements for quality and turnaround time. The ...

MyOme

Clinical Genomic Specialist

Chicago, IL

$110K - $140K/yr

Our team is composed of seasoned entrepreneurs, scientists, and operators, and we're backed by top ... Perform variant assessment and classification across proactive and rare disease whole genome ...

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Clinical Genomic Variant Scientist information

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How much do clinical genomic variant scientist jobs pay per hour?

As of Jul 27, 2026, the average hourly pay for clinical genomic variant scientist in the United States is $54.75, according to ZipRecruiter salary data. Most workers in this role earn between $40.14 and $68.27 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Clinical Genomic Variant Scientist, and why are they important?

To thrive as a Clinical Genomic Variant Scientist, you need expertise in genetics, molecular biology, and bioinformatics, typically backed by an advanced degree in a life science field. Familiarity with next-generation sequencing (NGS) platforms, variant interpretation tools (like ClinVar or HGMD), and clinical reporting software is essential. Strong analytical thinking, attention to detail, and effective communication skills set top performers apart in this role. These competencies are crucial for accurately interpreting genetic data, ensuring reliable clinical reporting, and collaborating effectively with healthcare teams.

What is the difference between Clinical Genomic Variant Scientist vs Molecular Geneticist?

AspectClinical Genomic Variant ScientistMolecular Geneticist
CredentialsMaster's or PhD in genetics, genomics, or related field; certification may be preferredMaster's or PhD in genetics, molecular biology, or related field; certification optional
Work EnvironmentLaboratories, hospitals, research institutions focusing on clinical diagnosticsResearch labs, hospitals, or academic settings focusing on genetic research and testing
Employer & Industry UsageHealthcare providers, diagnostic labs, biotech companiesAcademic institutions, research organizations, clinical labs

The main difference is that Clinical Genomic Variant Scientists focus on interpreting genetic variants for clinical diagnostics, often working directly with patient data, while Molecular Geneticists may work more broadly in research or laboratory settings without direct clinical responsibilities.

What are some common challenges Clinical Genomic Variant Scientists face when interpreting genetic data?

Clinical Genomic Variant Scientists often encounter challenges such as distinguishing between variants of uncertain significance and those with clear clinical relevance, due to the complexity and volume of genomic data. Staying up-to-date with rapidly evolving research and variant databases is crucial, as new discoveries can change the interpretation of previously classified variants. Collaboration with clinicians, genetic counselors, and bioinformaticians is essential to ensure accurate reporting and patient care. Additionally, maintaining rigorous documentation and adhering to clinical guidelines is key to ensuring high-quality results.

What is a Clinical Genomic Variant Scientist?

A Clinical Genomic Variant Scientist is a specialist who analyzes and interprets genetic variants found in patient DNA to determine their clinical significance. They work closely with clinicians and genetic counselors to provide insights into how specific genetic changes may contribute to disease, influence treatment, or affect patient outcomes. Their role often involves reviewing genetic data, consulting scientific literature, and applying guidelines to classify variants as benign, pathogenic, or of uncertain significance. This work is crucial for precision medicine and informing patient care. Many Clinical Genomic Variant Scientists are employed in hospitals, diagnostic laboratories, or research institutions.
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What job categories do people searching Clinical Genomic Variant Scientist jobs look for? The top searched job categories for Clinical Genomic Variant Scientist jobs are:
Clinical Genomic Variant Scientist jobs near you
Infographic showing various Clinical Genomic Variant Scientist job openings in the United States as of July 2026, with employment types broken down into 2% As Needed, 73% Full Time, 17% Part Time, and 8% Contract. Highlights an 95% Physical, 1% Hybrid, and 4% Remote job distribution, with an average salary of $113,877 per year, or $54.7 per hour.
Clinical Genomics Variant Scientist

Clinical Genomics Variant Scientist

UCLA Health

Los Angeles, CA

$105K - $234K/yr

Full-time

Posted 29 days ago

UCLA Health rating

8.7

Company rating: 8.7 out of 10

Based on 136 frontline employees who took The Breakroom Quiz

7th of 890 rated healthcare providers

Job description

Description

The Molecular Diagnostics Laboratory is seeking an experienced Variant Scientist to join our clinical team. In this critical role, you will curate and interpret germline and somatic variants and prepare high-quality clinical reports derived from exome and targeted cancer sequencing assays. You will contribute to variant classification, test development efforts, and clinical research projects that advance precision medicine for patients across UCLA Health and beyond. Primary duties include:

• Review and assess patient clinical notes and sequencing data from high-complexity molecular assays, including Clinical Exome Sequencing, Solid Tumor Sequencing Panels, and Hematologic Malignancy Sequencing Panels.

• Perform variant curation and interpretation using established guidelines and evidence-based resources.

• Draft and refine clinical reports, ensuring accuracy, clarity, and clinical relevance.

• Develop and update SOPs for variant curation, interpretation, and reclassification workflows

• Participate in submitting curated variants to public databases (e.g. ClinVar) and contribute to quality improvement and test development initiatives.

• Collaborate with clinicians, genetic counselors, and laboratory staff to support accurate and timely reporting.

• Contribute to clinical research projects and assist in implementing new molecular diagnostic assays.

Salary Range: $105,700.00 - $234,500.00/year 

Qualifications
• At least two years’ experience in germline variant curation is required. Somatic variant curation experience is a plus.
• Strong working knowledge of laboratory genetics and genomics, including target capture, amplification, and massively parallel sequencing.
• Familiarity with widely used genomic tools such as IGV and UCSC/COSMIC genome browsers
• Ability to establish effective working relationships with clinicians, genetic counselors, and other team members.
• Programming or bioinformatics experience (e.g. R, SAS, Perl, Python, regex, database design) – preferred.
• PhD in human genetics, molecular genetics, cancer biology, or a related discipline – preferred. Master’s degree in molecular biology, genetics, or a closely related field may be considered with relevant experience.

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About UCLA Health

Sourced by ZipRecruiter

UCLA Health, operating within the healthcare industry, is significantly recognized for its commitment to improving the health and wellbeing of people through the integration of patient care, research, and education. Located in Los Angeles, California, UCLA Health was founded and associated with the University of California, Los Angeles (UCLA) in 1955, entrenching its roots in quality healthcare service provision. Through a broad range of medical services, UCLA Health significantly stands as a cornerstone for comprehensive outpatient, inpatient, and emergency care services, specialized treatments, and wellness checks. Notable for pioneering an integrated, comprehensive medical approach, UCLA Health is consistently ranked among the top health systems in the US and world.

Industry

Health care and social assistance

Company size

10,000+ Employees

Headquarters location

Los Angeles, CA, US

Year founded

1955

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