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Clinical Genomic Variant Scientist Jobs (NOW HIRING)

EdenRoc Sciences

Scientific Sales, Oncology

San Diego, CA · On-site

$80K - $120K/yr

This role will support our genomic variant products and services business unit-directly targeting ... Position Requirements: • Bachelor of Science • 3-5+ years' proven track record selling into the ...

LatchBio

AI Biologist - Variant

San Francisco, CA · On-site +1

$120K - $180K/yr

... scientists across 150+ R&D labs to handle data from instrument-to-insights. We're seeking a ... Deep expertise in at least one of: population genetics, statistical genetics, clinical genomics

Belay Diagnostics

Clinical Data Abstractor

Chicago, IL · On-site

$50K - $70K/yr

The Clinical Data Abstractor will work closely with Clinical Genomic Analysts/Scientists and ... variant interpretation and clinical reporting * Maintain internal laboratory databases ...

Belay Diagnostics

Clinical Data Abstractor

Chicago, IL · On-site

$50K - $70K/yr

The Clinical Data Abstractor will work closely with Clinical Genomic Analysts/Scientists and ... variant interpretation and clinical reporting * Maintain internal laboratory databases ...

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Clinical Genomic Variant Scientist information

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How much do clinical genomic variant scientist jobs pay per hour?

As of Aug 7, 2026, the average hourly pay for clinical genomic variant scientist in the United States is $54.75, according to ZipRecruiter salary data. Most workers in this role earn between $40.14 and $68.27 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a clinical genomic variant scientist?

To thrive as a Clinical Genomic Variant Scientist, you need expertise in genetics, molecular biology, and bioinformatics, typically backed by an advanced degree in a life science field. Familiarity with next-generation sequencing (NGS) platforms, variant interpretation tools (like ClinVar or HGMD), and clinical reporting software is essential. Strong analytical thinking, attention to detail, and effective communication skills set top performers apart in this role. These competencies are crucial for accurately interpreting genetic data, ensuring reliable clinical reporting, and collaborating effectively with healthcare teams.

What is the difference between Clinical Genomic Variant Scientist vs Molecular Geneticist?

AspectClinical Genomic Variant ScientistMolecular Geneticist
CredentialsMaster's or PhD in genetics, genomics, or related field; certification may be preferredMaster's or PhD in genetics, molecular biology, or related field; certification optional
Work EnvironmentLaboratories, hospitals, research institutions focusing on clinical diagnosticsResearch labs, hospitals, or academic settings focusing on genetic research and testing
Employer & Industry UsageHealthcare providers, diagnostic labs, biotech companiesAcademic institutions, research organizations, clinical labs

The main difference is that Clinical Genomic Variant Scientists focus on interpreting genetic variants for clinical diagnostics, often working directly with patient data, while Molecular Geneticists may work more broadly in research or laboratory settings without direct clinical responsibilities.

How much do clinical genomic variant scientists make?

Clinical genomic variant scientists typically earn between $70,000 and $120,000 annually, depending on experience, education, and location. Salaries can increase with specialized skills, certifications, and working in high-demand healthcare or research environments.

What are some common challenges clinical genomic variant scientists face when interpreting genetic data?

Clinical Genomic Variant Scientists often encounter challenges such as distinguishing between variants of uncertain significance and those with clear clinical relevance, due to the complexity and volume of genomic data. Staying up-to-date with rapidly evolving research and variant databases is crucial, as new discoveries can change the interpretation of previously classified variants. Collaboration with clinicians, genetic counselors, and bioinformaticians is essential to ensure accurate reporting and patient care. Additionally, maintaining rigorous documentation and adhering to clinical guidelines is key to ensuring high-quality results.

What is a clinical genomic variant scientist?

A Clinical Genomic Variant Scientist is a specialist who analyzes and interprets genetic variants found in patient DNA to determine their clinical significance. They work closely with clinicians and genetic counselors to provide insights into how specific genetic changes may contribute to disease, influence treatment, or affect patient outcomes. Their role often involves reviewing genetic data, consulting scientific literature, and applying guidelines to classify variants as benign, pathogenic, or of uncertain significance. This work is crucial for precision medicine and informing patient care. Many Clinical Genomic Variant Scientists are employed in hospitals, diagnostic laboratories, or research institutions.
More about Clinical Genomic Variant Scientist jobs
What job categories do people searching Clinical Genomic Variant Scientist jobs look for? The top searched job categories for Clinical Genomic Variant Scientist jobs are:
Clinical Genomic Variant Scientist jobs near you
Infographic showing various Clinical Genomic Variant Scientist job openings in the United States as of August 2026, with employment types broken down into 90% Full Time, 5% Part Time, and 5% Contract. Highlights an 75% In-person, 5% Hybrid, and 20% Remote job distribution, with an average salary of $113,877 per year, or $54.7 per hour.

Associate Staff Scientist - Clinical Variant Curator

Cincinnati Children's

Cincinnati, OH • On-site

Full-time

Re-posted 3 days ago

Cincinnati Children's Hospital Medical Center rating

7.3

Company rating: 7.3 out of 10

Based on 150 frontline employees who took The Breakroom Quiz

385th of 1,055 rated hospitals

Job description

Primary Location
Kasota - 3244 Burnet
Department
Human Genetics
Shift
Day (United States of America)
Schedule
Full time
Weekly Hours
40
FTE
1
Employee Status
Regular
We are looking for a highly motivated individual with s PhD (or equivalent) degree in molecular genetics, molecular biology, or related field, who is passionate in applying life-science knowledge to clinical data analysis and interpretation.
Candidates with an MSc in Genetic Counselling are encouraged to apply. The candidate will join a team of genomic scientists (clinical variant curators), bioinformaticians, genetic counselors, and board-certified laboratory genetics directors who perform next-generation sequencing (NGS) data processing and analysis on clinical samples. The candidate would be mainly focused on conducting variant interpretations in molecular diagnostic tests and participating in molecular test development in a clinical laboratory.
The Genetics and Genomics Diagnostic Laboratory (GGDL) CLIA-Experience in a Clinical Genetics laboratory/ pediatric clinical setting certified and CAP-accredited lab in the Division of Human Genetics. We combine state-of-the-art genetic testing with comprehensive interpretation of tet results by board-certified clinical specialists, PhD genomic scientists (clinical variant curators) and genetic counselors to offer a broad range of molecular and cytogenetic diagnostic services in support of patient care. We are engaged in collaborative interactions with clinicians, physician-scientists and research investigators to translate scientific discoveries into robust genetic diagnostics. We are moving exome- and genome-based testing into mainstream pediatric diagnosis by offering comprehensive next-generation sequencing technology, combined with advanced bioinformatics to provide high quality clinical results.
JOB RESPONSIBILITIES
  • Conduct Research - Genetic data analysis - conducting variant interpretation for clinical genome sequencing, exome sequencing, NGS panel , and single gene tests. Understand medical terminologies and the functionalities of major human genetics information databases, including OMIM, HGMD, ClinVar, and gnomAD. Review patient's clinical history, family pedigree and physician notes. Establish genotype-phenotype correlations and conduct pathogenicity assessment of variants by complete evaluation of gene and variant information. Design, execute and record laboratory experiments; apply standard scientific/research protocols to experiments, research and improve current methods and evaluate innovative techniques. Design and perform experiments and record data according to research protocol. Independently reproduce, evaluate, research and improve techniques currently used. Adapt new methods to existing procedures and modify current experiments through scientific knowledge and intuition. Maintain accurate and detailed records of all laboratory work and experiments. Develop, set-up and verify new procedures in the laboratory. Standardize and establish new published procedures; evaluate innovative techniques. Develop new assays and new protocols; design formats. Discuss relevant insights about experimental results with Director and provide useful recommendations and analysis. Troubleshoot and correct erroneous results or problems with laboratory equipment. Maintain and repair equipment; monitor proper use by personnel. Maintain optimal protocol and assay accuracy by conducting regular quality and reproducibility checks. Demonstrate performance at work, consistency in carrying out instructions, accuracy & attention to detail, achieving expected results & continuous improvement.
  • Analysis Process Improvement - Contributing to analysis pipeline and procedure optimization, and in-house database update and improvement. Provide professional opinions and feedback on existing pipelines and databases, as well as commercial pipelines/ tools to make differences in improving the efficiencies and qualities of the services.
  • Development - Contributing to the development of clinical tests, and to the establishment of standard operating protocols, policies, and other documentations. Keep track of the field of molecular diagnosis, and identify the areas of new test development. Participate in in generating candidate gene lists, establishment of procedure, and test validation
  • Professional communications - Engaging in clinical and scientific discussions and presentations within the institution or at scientific conferences. Attend meetings on exome case discussion, and present clinical findings in the molecule genetics laboratory meetings. Attend and present scientific findings at scientific conferences.
  • Publish - Draft, write and edit scientific reports, papers, journal articles and abstracts. Present at local, national and international scientific meetings.
  • Teamwork - Effectively communicate with physicians, clinical variant curators, genetic counselors, lab technologists, bioinformatic specialists, and laboratory directors. Provide specific expert opinions on variants, genes and clinical findings. Work collaboratively with various teams within the laboratory. Train and supervise the work of other laboratory personnel as appropriate. Maintain an integral role in the laboratory's meetings, presentations and publications. Present information on research and laboratory work to others at laboratory meetings, journal clubs and seminars. Demonstrate attendance and punctuality, ability to work independently & display initiative and dedication
  • Financial Management - Assist in preparing, writing and maintaining fiscal budget. Monitor expenditures and prepare capital expenditure requests. Prepare, approve and initiate check requests; track funding, maintain accurate balance and resolve any discrepancies.
  • Leadership - May act as a mentor to more junior staff, serve as the contact for resolution of complex issues, provide education, guidance and work direction. May provide input and feedback to managers on hiring decisions, professional development and performance management.

JOB QUALIFICATIONS
  • PhD
  • 3+ years of work experience in a related job discipline

About Us
At Cincinnati Children's, we come to work with one goal: to make children's health better. We believe in a holistic team approach, both in caring for patients and their families, and in advancing science and discovery. We strive to do better and find energy and inspiration in our shared purpose. If you want to be the best you can be, you can do it at Cincinnati Children's.
Cincinnati Children's is:
  • Recognized by U.S. News & World Report as a top 10best Children's Hospitals in the nation for more than 15 years
  • Consistently among the top 3 Children's Hospitals for National Institutes of Health (NIH) Funding
  • Recognized as one of America's Best Large Employers (2025), America's Best Employers for New Grads (2025)
  • One of the nation's America's Most Innovative Companies as noted by Fortune
  • Consistently certified as great place to work
  • A Leading Disability Employer as noted by the National Organization on Disability
  • Magnet® designated for the fourth consecutive time by the American Nurses Credentialing Center (ANCC)

We Embrace Innovation-Together. We believe in empowering our teams with the tools that help us work smarter and care better. That's why we support the responsible use of artificial intelligence. By encouraging innovation, we're creating space for new ideas, better outcomes, and a stronger future-for all of us.
Comprehensive job description provided upon request.
Cincinnati Children's is proud to be an Equal Opportunity Employer committed to creating an environment of dignity and respect for all our employees, patients, and families. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, age, genetic information, national origin, sexual orientation, gender identity, disability or protected veteran status. EEO/Veteran/Disability

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About Cincinnati Children's Hospital Medical Center

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Cincinnati Children's Hospital Medical Center, located in Cincinnati, OH, US, is a premier pediatric hospital renowned for its exceptional clinical services, research programs, and medical education. The healthcare institution, founded in 1883, holds a sterling reputation in the industry, with a mission to improve child health and transform delivery of care through fully integrated, globally recognized research, education and innovation. As one of the oldest and most distinguished pediatric hospitals in the United States, Cincinnati Children's continues to offer a broad range of high-quality, compassionate care to children in the community and around the globe. As a testament to its dedication, it has consistently been ranked among the top three US pediatric hospitals by U.S. News & World Report.

Industry

Hospitals

Company size

10,000+ Employees

Headquarters location

Cincinnati, OH, US

Year founded

1883

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