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Clinical Database Programmer Jobs in Massachusetts

Smith & Nephew

Director, Clinical Data & AI

Andover, MA · On-site

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

Data management and data engineering * AI/ML and advanced analytics * Serve as the enterprise ... Efficient study startup (eCRF design, database builds) and closeout * Risk-based monitoring and ...

Massgeneralbrigham

Programmer II

Boston, MA · On-site

$36.19 - $52.67/hr

Develop/design and upgrade models for guiding clinical decision making with treatment resistant ... databases, SQL and ORM technologies. - Detail-oriented and excellent concentration ability. - An ...

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Showing results 21-40

All JobsClinical Database Programmer JobsClinical Database Programmer Jobs in Massachusetts

Clinical Database Programmer information

See Massachusetts salary details

$75.9K

$129.9K

$231.5K

How much do clinical database programmer jobs pay per year?

As of Aug 16, 2026, the average yearly pay for clinical database programmer in Massachusetts is $129,921.00, according to ZipRecruiter salary data. Most workers in this role earn between $87,400.00 and $196,600.00 per year, depending on experience, location, and employer.

What is a clinical database programmer?

A Clinical Database Programmer is responsible for designing, developing, and maintaining databases used in clinical trials. They ensure that data is collected, stored, and managed efficiently while complying with regulatory standards such as CDISC and FDA guidelines. Their role involves creating database structures, writing validation checks, and supporting data analysis to ensure accurate and reliable clinical trial results. They often work with clinical data managers, biostatisticians, and regulatory teams.

What are the key skills and qualifications needed to thrive as a clinical database programmer?

To excel as a Clinical Database Programmer, you need a bachelor's degree in computer science or a related field, experience in database design, and a strong understanding of clinical data standards. Proficiency in database management systems (such as Oracle or SQL), knowledge of electronic data capture (EDC) tools like Medidata Rave, and familiarity with programming languages like SAS or SQL are commonly required, along with certifications such as CDISC or Medidata Solutions. Attention to detail, problem-solving ability, and strong communication skills are valuable soft skills for this role. Mastering these competencies is vital for ensuring high-quality, regulatory-compliant clinical trial data and effective collaboration within multidisciplinary research teams.

What are common responsibilities and team interactions for a clinical database programmer in a typical workweek?

As a Clinical Database Programmer, your primary responsibilities usually include designing, building, and validating clinical trial databases, ensuring data is collected and managed in compliance with industry standards and regulatory requirements. You will frequently collaborate with clinical data managers, biostatisticians, and study coordinators to define data collection requirements and resolve data discrepancies. Team meetings and cross-functional communication are integral parts of the role, as you work together to maintain database integrity throughout the study lifecycle. This collaborative environment provides valuable experience in both technical problem-solving and teamwork, often paving the way for advancement into senior programming or data management positions.

What are the most commonly searched types of Clinical Database Programmer jobs in Massachusetts?

The most popular types of Clinical Database Programmer jobs in Massachusetts are:

What are popular job titles related to Clinical Database Programmer jobs in Massachusetts?

For Clinical Database Programmer jobs in Massachusetts, the most frequently searched job titles are:

What job categories do people searching Clinical Database Programmer jobs in Massachusetts look for?

The top searched job categories for Clinical Database Programmer jobs in Massachusetts are:

What are popular job titles related to Clinical Database Programmer jobs in MA?

For Clinical Database Programmer jobs in MA, the most frequently searched job titles are:

Clinical Database Programmer jobs near you
Infographic showing various Clinical Database Programmer job openings in Massachusetts as of August 2026, with employment types broken down into 2% As Needed, 77% Full Time, 15% Part Time, and 6% Contract. Highlights an 95% Physical, 1% Hybrid, and 4% Remote job distribution, with an average salary of $129,921 per year, or $62.5 per hour.

Manager Clinical Data

Monte Rosa Therapeutics, Inc

Boston, MA

Full-time

Re-posted 7 days ago

Job description

Overview

The Manager, Data Management will be responsible for overseeing clinical data management activities across one or more clinical programs. This individual will work closely with Clinical Operations, Biostats and  Programming, Medical, Safety, Regulatory, external CROs, and technology vendors to ensure high-quality, inspection-ready clinical data.

This is a hands-on role well suited for someone who thrives in a small biotech environment, can manage external partners effectively, and is comfortable moving between strategy, execution, and problem-solving.

Responsibilities
  • Oversee end-to-end clinical data management activities for assigned studies, from study start-up through database lock.
  • Manage CROs, EDC vendors, central labs, imaging vendors, eCOA providers, IRT vendors, and other data providers.
  • Review and contribute to key study documents, including data management plans, edit check specifications, CRF completion guidelines, data transfer agreements, and data review plans.
  • Support CRF design, database build, user acceptance testing, and EDC system validation activities.
  • Ensure timely data cleaning, query management, reconciliation, coding, and database lock activities.
  • Coordinate external data transfers and reconciliations, including laboratory, pharmacokinetic, biomarker, imaging, safety, and IRT data.
  • Partner with Clinical Operations and study teams to identify data quality issues and drive resolution.
  • Support medical coding activities using MedDRA and WHODrug, as applicable.
  • Contribute to clinical data review meetings and help prepare data outputs for internal decision-making.
  • Maintain data management documentation in compliance with GCP, ICH guidelines, SOPs, and regulatory expectations.
  • Support vendor selection, budget review, timelines, performance oversight, and issue escalation.
  • Contribute to process development and continuous improvement as the company scales its clinical operations infrastructure.
Qualifications
  • BS/MS degree in life sciences, data sciences, health sciences, or a related field.
  • 8+ years of clinical data management experience in biotech, pharmaceutical, CRO, or related clinical research settings.
  • Experience supporting oncology and/or immune disease clinical trials.
  • Strong working knowledge of EDC systems such as Medidata Rave or similar platforms.
  • Experience managing CROs and external clinical data vendors.
  • Familiarity with clinical trial data standards, including CDISC, SDTM concepts, and database lock processes.
  • Understanding of GCP, ICH guidelines, regulatory requirements, and clinical trial documentation standards.
  • Strong attention to detail, organizational skills, and ability to manage multiple priorities in a fast-paced environment.
  • Excellent communication and cross-functional collaboration skills.
  • Experience in a small biotech or emerging pharmaceutical company.
  • Experience with early-phase oncology trials, dose escalation, expansion cohorts, and complex biomarker-driven studies.
  • Familiarity with molecularly targeted therapies, protein degradation, or immune-mediated disease programs.
  • Experience with external data types such as genomics, biomarkers, PK/PD, central imaging, and specialty labs.
Employment Type: FULL_TIME

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