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Chief Operations Manager Jobs in Massachusetts (NOW HIRING)

Financial Operations Manager

Lowell, MA · On-site

$90K - $110K/yr

HiFyve is hiring an Accounting Operations Manager for a growing organization where you'll report directly to the CFO and have the autonomy to improve accounting operations, strengthen processes, and ...

POSITION TITLE: Chief Commercial Officer (CCO) LOCATION: Cambridge, MA (Hybrid) This position ... Oversee commercial operations including revenue operations, sales enablement, CRM strategy ...

OPERATIONS MANAGER Full-Time | On-Site | Reports to CEO About the Role We are looking for a seasoned Operations Manager to take full ownership of our operational backbone. This is a leadership role ...

OPERATIONS MANAGER Full-Time | On-Site | Reports to CEO About the Role We are looking for a seasoned Operations Manager to take full ownership of our operational backbone. This is a leadership role ...

Chief Customer Officer Position Contingency Notice: This position is associated with Bay State Rail ... Experience managing customer communications and service recovery during operational disruptions.

Chief Customer Officer

Boston, MA · On-site

$200K - $280K/yr

Chief Customer Officer Position Contingency Notice: This position is associated with Bay State Rail ... Experience managing customer communications and service recovery during operational disruptions.

Strategic Operations Manager

Boston, MA · On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Position Overview The Strategic Operations Manager is part of the Payments Business Unit team ... Reporting to the Chief of Staff, this role sits at the intersection of strategy and execution ...

You will be the operational right hand to the CEO, ensuring that internal systems, logistics ... Manage multiple concurrent priorities with urgency and precision, ensuring nothing falls through ...

Showing results 21-40

Chief Operations Manager information

See Massachusetts salary details

$33.9K

$69.3K

$129.4K

How much do chief operations manager jobs pay per year?

As of Aug 16, 2026, the average yearly pay for chief operations manager in Massachusetts is $69,302.00, according to ZipRecruiter salary data. Most workers in this role earn between $44,800.00 and $84,600.00 per year, depending on experience, location, and employer.

How does a chief operations manager typically collaborate with other executive leaders to drive organizational success?

A Chief Operations Manager (COM) works closely with other executive leaders, such as the CEO, CFO, and department heads, to align operational strategies with overall business goals. This collaboration often involves regular strategy meetings, cross-functional project management, and the integration of feedback from various departments to optimize efficiency. The COM is responsible for ensuring that operational initiatives support both short-term objectives and long-term growth, often serving as a bridge between upper management and frontline teams. Building strong working relationships and maintaining transparent communication are key to driving successful outcomes.

What is a chief operations manager?

Chief Operations Managers are senior executives responsible for overseeing the day-to-day operations of an organization. They ensure that business processes run efficiently and align with the company's strategic goals. Their duties often include managing operational budgets, supervising department heads, implementing policies, and improving productivity. Chief Operations Managers play a critical role in streamlining workflow and supporting the overall success of the organization.

What are the key skills and qualifications needed to thrive as a chief operations manager, and why are they important?

To thrive as a Chief Operations Manager, you need strong leadership, strategic planning, and operational management skills, typically backed by a bachelor’s or master’s degree in business administration or a related field. Familiarity with ERP systems, project management software, and certifications like PMP or Six Sigma are highly valued. Outstanding soft skills include problem-solving, communication, and adaptability for managing teams and cross-functional projects. These skills ensure efficient operations, drive organizational growth, and support effective decision-making at the executive level.

What cities in Massachusetts are hiring for Chief Operations Manager jobs?

Cities in Massachusetts with the most Chief Operations Manager job openings:

Infographic showing various Chief Operations Manager job openings in Massachusetts as of August 2026, with employment types broken down into 87% Full Time, 10% Part Time, 1% Temporary, and 2% Contract. Highlights an 94% Physical, 2% Hybrid, and 4% Remote job distribution, with an average salary of $69,302 per year, or $33.3 per hour.

Chief Commercial Officer (CCO)

trinetx1

Cambridge, MA • Hybrid

Full-time

Posted 17 days ago


Job description

POSITION TITLE: Chief Commercial Officer (CCO)

LOCATION: Cambridge, MA (Hybrid)

This position reports to our global HQ in Cambridge, MA and is hybrid with 2-3 days onsite. Travel is expected domestically and internationally when needed.

Who We Are:

TriNetX connects healthcare organizations and researchers across the globe so they can transparently see what's happening in real patient populations.

Our aim is simple and ambitious: Provide a clear path to trustworthy answers, whether your goal is to create promising new therapies, publish groundbreaking research, or improve health outcomes.

We keep identifiable data where it belongs—inside more than 11,000+ clinical sites across 20+ countries—preserving security, provenance, and granularity. Our trusted partnerships with providers ensure high-fidelity data, and a properly governed linkage back to individual patients.

At TriNetX, we enable life sciences, healthcare, and academic institutions to strengthen human health—with data you can trace, evidence you can defend, and answers you can trust.

Who We Are Looking For:

The Chief Commercial Officer (CCO) will serve as the senior executive commercial leader at TriNetX, responsible for driving the company's global revenue strategy and go-to-market execution. This executive will own and integrate critical commercial functions — marketing, commercial operations, healthcare organization (HCO)network opertaions, sales, and account management to deliver cohesive growth across all market segments. Reporting directly to the CEO, the CCO will be a key member of the executive leadership team and a champion of TriNetX's mission to strengthen human health with data you can trust.

What You Will Be Doing:

  • Strategic Commercial Leadership: Define and execute TriNetX's global commercial strategy across all revenue-generating and network-building functions. Serve as the primary commercial voice on the executive leadership team, partnering with the CEO and Board on commercial direction, market positioning, and growth initiatives.
  • Marketing & Brand: Lead the global marketing function, including product marketing, demand generation, content, communications, and brand strategy. Drive integrated go-to-market campaigns that build brand awareness, generate qualified pipeline, and differentiate TriNetX in the market.
  • Commercial Operations: Oversee commercial operations including revenue operations, sales enablement, CRM strategy, forecasting, and compensation design. Ensure data-driven, scalable processes that allow the full commercial organization to operate with efficiency and accountability.
  • HCO Network Operations: Own the healthcare organization (HCO) network operations function, responsible for acquiring, onboarding, expanding, and retaining TriNetX's global network of healthcare member organizations. Develop and execute strategies to deepen HCO engagement, maximize data contribution, and grow the value of the network for all stakeholders.
  • Revenue Growth & Accountability: Set and achieve ambitious bookings and revenue targets across all commercial segments. Align Marketing, Commercial Operations, and HCO Network Operations with the Sales & Account Management organization to ensure seamless pipeline generation and client growth.
  • Cross-Functional Partnership: Serve as the connective tissue between Commercial, Product, Finance, Legal, and Operations. Ensure product roadmap, pricing, and delivery are tightly integrated with market feedback and commercial priorities.
  • Team Leadership & Organizational Development: Build, lead, and scale a high-performing commercial organization. Develop and mentor senior leaders across marketing, commercial ops, and HCO network functions. Champion a culture of accountability, inclusivity, collaboration, and continuous improvement.
  • Market Intelligence & Competitive Positioning: Monitor industry trends, regulatory developments, and competitive dynamics across the global life sciences and real-world data landscape. Represent TriNetX at industry conferences, advisory boards, and strategic partner engagements.

What You Bring to TriNetX:

  • Bachelor's degree required; MBA or advanced degree strongly preferred.
  • 15+ years of progressive commercial leadership experience, with at least 5 years in a senior executive role (VP, SVP, or C-suite) within life sciences, health technology, SaaS, or real-world data/analytics.
  • Proven track record of owning and scaling a commercial organization, with demonstrated success driving bookings and revenue growth across diverse market segments.
  • Deep experience leading and integrating multiple commercial functions, including marketing, commercial or revenue operations, and network or partner development.
  • Demonstrated ability to build, grow, and manage healthcare organization, health system, or strategic partner networks at scale.
  • Experience working closely with and presenting to a Board of Directors and cross-functional executive leadership team.
  • Exceptional strategic thinking, executive communication, and leadership presence — able to inspire internal teams and represent TriNetX externally at the highest levels.
  • Strong analytical foundation with comfort owning commercial metrics, forecasting models, and performance reporting.
  • Ability to thrive in a fast-paced, globally distributed, high-growth environment with complex stakeholder dynamics.
  • Willingness to travel domestically and internationally as needed.

Learn more about TriNetX:

To learn more about us, please check out our website, blog, and Careers page - and be sure to follow us on LinkedIn. 

Interested in joining our community?

TriNetX is an Equal Opportunity Employer. All persons are considered for employment without regard to their race, color, creed, religion, national origin, ancestry, citizenship status, age, disability or handicap, sex or gender, marital status, sexual orientation, genetic information, gender identity, veteran status, or any other characteristic or status protected by applicable federal, state or local laws.

This Organization Participates in E-Verify

This employer participates in E-Verify and will provide the federal government with your Form I-9 information to confirm that you are authorized to work in the U.S. If E-Verify cannot confirm that you are authorized to work, this employer is required to give you written instructions and an opportunity to contact Department of Homeland Security (DHS) or Social Security Administration (SSA) so you can begin to resolve the issue before the employer can take any action against you, including terminating your employment. Employers can only use E-Verify once you have accepted a job offer and completed the Form I-9.

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