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Biotech Process Engineer Jobs in Massachusetts (NOW HIRING)

PBS Biotech Inc

Applications Engineer II

Brookline, MA · On-site

$109K - $131K/yr

PBS Biotech is an innovative, fast-growing biotechnology company headquartered in Camarillo ... Troubleshoot and resolve cell culture and process-related challenges in a timely manner * Provide ...

Amgen Inc

Sr. Data Scientist - Process Modeling

Boston, MA · On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

Chemical Engineering modeling, drug-substance, tech-transfer experience * 3+ years of work experience in biotechnology role (e.g. process engineer, scientist, data scientist) * Experience with AGILE ...

New

Amgen, Inc.

Sr. Data Scientist - Process Modeling

Boston, MA · On-site +1

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

Chemical Engineering modeling, drug-substance, tech-transfer experience * 3+ years of work experience in biotechnology role (e.g. process engineer, scientist, data scientist) * Experience with AGILE ...

Syner-G

Reliability Engineer

Boston, MA · On-site

$111K - $140K/yr

  • PTO

... biotechnology, pharmaceutical, R&D, or another highly regulated manufacturing environment preferred. * Experience in Reliability Engineering, Facilities Engineering, Process Engineering, Plant ...

Danaher

Senior Engineer, Process Validation

Boston, MA · On-site +1

$100K - $130K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

... biotechnology? At Aldevron, one of Danaher's 15+ operating companies, our work saves lives-and we ... The Senior Engineer, Process Validation is responsible for leading & supporting internal and ...

Danaher

Senior Engineer, Process Validation

Boston, MA · On-site +1

$100K - $130K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

... biotechnology? At Aldevron, one of Danaher's 15+ operating companies, our work saves lives-and we ... The Senior Engineer, Process Validation is responsible for leading & supporting internal and ...

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Showing results 41-60

All JobsBiotech Process Engineer JobsBiotech Process Engineer Jobs in Massachusetts

Biotech Process Engineer information

See Massachusetts salary details

$54.1K

$100.5K

$155.6K

How much do biotech process engineer jobs pay per year?

As of Aug 15, 2026, the average yearly pay for biotech process engineer in Massachusetts is $100,495.00, according to ZipRecruiter salary data. Most workers in this role earn between $81,400.00 and $112,500.00 per year, depending on experience, location, and employer.

What is the difference between Biotech Process Engineer vs Biotech Manufacturing Technician?

AspectBiotech Process EngineerBiotech Manufacturing Technician
CredentialsBachelor's degree in biotech, chemical engineering, or related field; often requires experience in process designAssociate's or bachelor's degree; focus on operational skills and equipment handling
Work EnvironmentDesigning, optimizing, and overseeing production processes in labs or manufacturing facilitiesOperating and maintaining equipment on the manufacturing floor
Job FocusProcess development, scale-up, troubleshooting, and process improvementExecuting production tasks, quality checks, and equipment setup

Biotech Process Engineers focus on designing and improving manufacturing processes, requiring technical and analytical skills. In contrast, Biotech Manufacturing Technicians handle day-to-day production operations. Both roles are essential in biotech manufacturing but differ in responsibilities and required qualifications.

What are some common challenges faced by Biotech Process Engineers during scale-up from laboratory to production?

Biotech Process Engineers often encounter challenges when scaling up processes from laboratory or pilot scale to full production. These challenges can include maintaining product consistency, ensuring process sterility, and adapting equipment to handle larger volumes without compromising yield or quality. Engineers must also collaborate closely with cross-functional teams such as quality assurance, validation, and manufacturing to implement changes efficiently and adhere to regulatory standards. Proactive problem-solving and strong communication skills are key to overcoming these hurdles and ensuring successful technology transfer.

What does a Biotech Process Engineer do?

A Biotech Process Engineer designs, develops, and optimizes processes used in the production of biological products such as pharmaceuticals, vaccines, and biofuels. They work closely with scientists and manufacturing teams to scale up lab procedures to industrial levels while ensuring product quality and regulatory compliance. Their role often involves troubleshooting equipment, improving efficiency, and implementing new technologies within biotech manufacturing environments.

What are the key skills and qualifications needed to thrive as a Biotech Process Engineer, and why are they important?

To thrive as a Biotech Process Engineer, you need a solid background in chemical or biochemical engineering, process design, and regulatory compliance, typically supported by a relevant bachelor's or master's degree. Familiarity with process control systems, bioprocess simulation software, and industry-standard quality systems such as cGMP is essential. Strong analytical thinking, problem-solving abilities, and effective teamwork and communication skills help you excel in cross-functional environments. These skills ensure efficient, compliant, and innovative bioprocess operations, which are critical for product quality and organizational success.

What are popular job titles related to Biotech Process Engineer jobs in Massachusetts?

For Biotech Process Engineer jobs in Massachusetts, the most frequently searched job titles are:

What job categories do people searching Biotech Process Engineer jobs in Massachusetts look for?

The top searched job categories for Biotech Process Engineer jobs in Massachusetts are:

What cities in Massachusetts are hiring for Biotech Process Engineer jobs?

Cities in Massachusetts with the most Biotech Process Engineer job openings:

Biotech Process Engineer jobs near you
Infographic showing various Biotech Process Engineer job openings in Massachusetts as of August 2026, with employment types broken down into 69% Full Time, and 31% Contract. Highlights an 92% In-person, and 8% Hybrid job distribution, with an average salary of $100,495 per year, or $48.3 per hour.

Senior Scientist / Senior Engineer, LNP Process Development

Prime Medicine

Cambridge, MA • On-site

$113K - $147K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 27 days ago

Job description

Company Overview:
Prime Medicine is a leading biotechnology company dedicated to creating and delivering the next generation of gene editing therapies to patients. The Company is leveraging its proprietary Prime Editing platform, a versatile, precise and efficient gene editing technology, to develop a new class of differentiated, one-time, potentially curative genetic therapies. Designed to make only the right edit at the right position within a gene while minimizing unwanted DNA modifications, Prime Editors have the potential to repair almost all types of genetic mutations and work in many different tissues, organs and cell types.
Prime Medicine is currently progressing a diversified portfolio of investigational therapeutic programs organized around our core areas of focus: hematology, immunology & oncology, liver and lung. Across each core area, Prime Medicine is focused initially on a set of high value programs, each targeting a disease with well-understood biology and a clearly defined clinical development and regulatory path, and each expected to provide the foundation for expansion into additional opportunities. For more information, please visit www.primemedicine.com.
Prime Medicine was founded to bring the promise of gene editing to patients. We use Prime Editing, a next-generation technology that can "search and replace" to restore normal genetic function almost anywhere in the genome. Prime Editing searches to find the precise place in the genome to edit and replace the segment of faulty DNA with a correct copy of DNA. A single Prime Editor can correct the individual mutations found across patients, meaning Prime Editing can potentially address more than 90 percent of known disease-causing genetic mutations.
We envision a world where this technology can cure, halt, and ultimately prevent genetic diseases, providing lifelong benefits to patients. Prime Medicine offers the opportunity to shape the future of gene editing and transform how medicines are used to treat disease.
Position Summary
The Senior Scientist / Senior Engineer, LNP Process Development will provide technical leadership for the development, characterization, and scale-up of robust, scalable lipid nanoparticle (LNP) formulation and drug product manufacturing processes. This individual will be responsible for driving LNP process development - spanning formulation, process optimization and characterization, scale-up, and technology transfer support for key pipeline assets.
Key Responsibilities
Technical Leadership & Process Development
  • Lead the design, execution, and optimization of LNP processes to accommodate novel formulations and drug product manufacturing processes (LNP mixing and tangential flow filtration [TFF]) from bench through GLP/GMP scale, with emphasis on developing robust and scalable processes
  • Serve as a subject matter expert for LNP process development across programs and therapeutic areas, partnering with Research, Platform, Hematology, and other teams to translate novel modalities into developable drug products
  • Evaluate and implement emerging technologies, novel materials, delivery and process innovations that continuously improve delivery efficiency, drug product quality, manufacturability, and cost of goods
  • Support technology transfer activities to external contract development and manufacturing organizations (CDMOs), including preparation of tech transfer packages, on-site execution support (Person-in-Plant), and process troubleshooting
  • Author and contribute to Chemistry, Manufacturing, and Controls (CMC) sections of regulatory filings, briefing books, and regulatory responses related to LNP drug product
  • Maintain impeccable documentation using electronic lab notebooks (ELNs); generate experimental protocols, development reports, technology transfer packages, SOPs, and technical reports to support clinical development
  • Communicate complex technical information clearly through presentations, written reports, and everyday collaboration to diverse audiences including cross-functional stakeholders and external partners

Qualifications & Experience
  • Ph.D. in Chemical Engineering, Biomedical Engineering, Chemistry, Pharmaceutical Sciences, Materials Science, or a related discipline with 8+ years of relevant industrial experience in LNP process development and formulation development; M.S. with 12+ years
  • Demonstrated expertise in LNP formulation processes, TFF operations, and related characterization methods
  • Hands-on experience with LNP delivery and formulation development, process scale-up from bench to GLP/GMP scale, and technology transfer to GMP facilities and/or CDMOs
  • Strong proficiency in analytical characterization techniques (HPLC/UPLC, DLS/SLS, TEM, DSC, SAXS, UV-Vis, fluorescence spectrophotometry) to support process development
  • Experience with statistical design of experiments (DoE) and knowledge of Quality by Design (QbD) methodologies
  • Hands-on experience with defining and setting up equipment systems for LNP and TFF processes
  • Knowledge of CMC regulatory requirements and experience contributing to IND/CTA submissions
  • Excellent communication skills, with the ability to effectively collaborate cross-functionally, prioritize activities to meet program goals, and present complex technical information to diverse audiences
  • Highly self-motivated with strong organizational skills, the ability to manage competing priorities, and a hands-on approach to problem-solving

The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on several factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus) and an annual long-term incentive award (e.g., equity).
Prime Medicine offers a comprehensive Total Rewards package with robust health, financial, and wellness benefits-including medical, dental, vision, life insurance, a 401(k) match, and equity programs-along with generous paid time off, wellness days, and company-wide recharge breaks.
Our commitment to employee well-being reflects our belief that when we care for our people, we strengthen our ability to put patients first and make meaningful impact together.
U.S. Pay Range
$145,000-$161,000 USD
Prime Medicine is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, age, sexual orientation, gender identity, disability, veteran status, or any other classification protected by law.

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