1

Biomedical Software Engineer Jobs in California (NOW HIRING)

Software Engineer

Santa Clara, CA · On-site

$179K - $246K/yr

As a Software Engineer at Applied Materials, you'll dive deep into ground-breaking technologies ... Preferred Qualifications MS+ in Electrical Engineering, Physics, Biomedical Engineering, Optical ...

Software Engineer

Santa Clara, CA · On-site

$179K - $246K/yr

Our Software Engineers are responsible for designing, prototyping, developing, and debugging ... MS+ in Electrical Engineering, Physics, Biomedical Engineering, Optical Engineering, Computer ...

Software Engineer

Santa Clara, CA · On-site

$179K - $246K/yr

Our Software Engineers are responsible for designing, prototyping, developing, and debugging ... MS+ in Electrical Engineering, Physics, Biomedical Engineering, Optical Engineering, Computer ...

About you We are looking for a software engineer who is excited to develop technology at the ... This is a unique opportunity to work across many areas of a hardtech biomedical startup, including ...

Students graduating in 2026 or later with a Bachelor's degree in Computer Science, Software Engineering, Biomedical Engineering (with computational focus), or related field * Preference for students ...

Students graduating in 2026 or later with a Bachelor's degree in Computer Science, Software Engineering, Biomedical Engineering (with computational focus), or related field * Preference for students ...

Students graduating in 2026 or later with a Bachelor's degree in Computer Science, Software Engineering, Biomedical Engineering (with computational focus), or related field * Preference for students ...

Students graduating in 2026 or later with a Bachelor's degree in Computer Science, Software Engineering, Biomedical Engineering (with computational focus), or related field * Preference for students ...

Students graduating in 2026 or later with a Bachelor's degree in Computer Science, Software Engineering, Biomedical Engineering (with computational focus), or related field * Preference for students ...

Students graduating in 2026 or later with a Bachelor's degree in Computer Science, Software Engineering, Biomedical Engineering (with computational focus), or related field * Preference for students ...

Students graduating in 2026 or later with a Bachelor's degree in Computer Science, Software Engineering, Biomedical Engineering (with computational focus), or related field * Preference for students ...

Students graduating in 2026 or later with a Bachelor's degree in Computer Science, Software Engineering, Biomedical Engineering (with computational focus), or related field * Preference for students ...

Students graduating in 2026 or later with a Bachelor's degree in Computer Science, Software Engineering, Biomedical Engineering (with computational focus), or related field * Preference for students ...

Students graduating in 2026 or later with a Bachelor's degree in Computer Science, Software Engineering, Biomedical Engineering (with computational focus), or related field * Preference for students ...

Students graduating in 2026 or later with a Bachelor's degree in Computer Science, Software Engineering, Biomedical Engineering (with computational focus), or related field * Preference for students ...

Students graduating in 2026 or later with a Bachelor's degree in Computer Science, Software Engineering, Biomedical Engineering (with computational focus), or related field * Preference for students ...

next page

Showing results 1-20

Biomedical Software Engineer information

See California salary details

$62.7K

$145.6K

$202.8K

How much do biomedical software engineer jobs pay per year?

As of Sep 4, 2026, the average yearly pay for biomedical software engineer in California is $145,592.00, according to ZipRecruiter salary data. Most workers in this role earn between $118,400.00 and $170,700.00 per year, depending on experience, location, and employer.

What is a biomedical software engineer?

A Biomedical Software Engineer develops software solutions for medical and healthcare applications, including medical devices, diagnostic tools, and research simulations. They combine biomedical knowledge with software development skills to create and maintain systems that improve patient care, enhance medical research, and ensure regulatory compliance. Their work often involves programming, data analysis, and collaboration with healthcare professionals and researchers.

What does a biomedical software engineer do?

Biomedical Software Engineers often work on designing, developing, and maintaining software used in medical devices, clinical diagnostics, or healthcare information systems. Typical responsibilities include coding new features, troubleshooting and resolving software issues, ensuring compliance with medical standards, and participating in quality assurance testing. You may also collaborate closely with clinicians, researchers, and regulatory specialists to align technological solutions with user needs and safety requirements. These projects frequently involve iterative development and rigorous validation to ensure reliability in real-world medical settings.

What skills and qualifications are needed to be a biomedical software engineer?

To thrive as a Biomedical Software Engineer, you need a strong background in computer science, biomedical engineering, and software development—often supported by a bachelor's or master's degree in a related field. Proficiency with programming languages such as Python, C++, or Java, familiarity with medical imaging tools, and experience working with healthcare interoperability standards like HL7 or DICOM are typically required. Effective communication, teamwork, and problem-solving skills are crucial for collaborating with cross-functional teams and understanding user requirements. These competencies ensure that biomedical software solutions are safe, compliant, and meet the complex needs of healthcare environments.

What job categories do people searching Biomedical Software Engineer jobs in California look for?

The top searched job categories for Biomedical Software Engineer jobs in California are:

What cities in California are hiring for Biomedical Software Engineer jobs?

Cities in California with the most Biomedical Software Engineer job openings:

Infographic showing various Biomedical Software Engineer job openings in California as of August 2026, with employment types broken down into 33% Internship, 33% Full Time, and 34% Contract. Highlights an 100% In-person job distribution, with an average salary of $145,592 per year, or $70 per hour.

BioMedical AI Research Engineer

Xaira Therapeutics

South San Francisco, CA

$227K - $295K/yr

Full-time

Re-posted 2 days ago


Key responsibilities

  • Design and implement agentic AI architectures capable of multi-step reasoning, planning, and tool use in biomedical contexts.

  • Develop LLM-based agents that retrieve, synthesize, evaluate, and act on biomedical information from various data sources.

  • Integrate external tools into autonomous agent workflows and evaluate system robustness and interpretability in biomedical settings.


Job description

About the Role
We are seeking a Biomedical AI Engineer to design and deploy agentic AI systems that can reason over biomedical knowledge, plan multi-step analyses, and autonomously integrate diverse scientific data sources to accelerate therapeutic discovery.

This role goes beyond traditional LLM + RAG pipelines. You will build AI agents that can retrieve, synthesize, evaluate, and act on biomedical information across literature, omics datasets, and clinical records operating as intelligent systems embedded within discovery workflows.

Key Responsibilities

  • Design and implement agentic AI architectures capable of multi-step reasoning, planning, and tool use in biomedical contexts.
  • Develop LLM-based agents that dynamically retrieve, rank, and synthesize knowledge from scientific literature, knowledge graphs, omics datasets, and clinical data.
  • Build memory and feedback mechanisms that allow agents to refine hypotheses, update context, and adapt to evolving data.
  • Integrate external tools (analysis pipelines, simulation engines, statistical models, databases) into autonomous agent workflows.
  • Architect scalable systems that combine structured and unstructured biomedical data within production-grade AI environments.
  • Collaborate closely with computational biologists, translational scientists, and software engineers to embed agentic systems into real-world discovery pipelines.
  • Evaluate robustness, reliability, and interpretability of autonomous systems in high-stakes biomedical settings.

Qualifications

  • Degree in Computer Science, Machine Learning, Computational Biology, Biomedical Informatics, or related field.
  • Strong hands-on experience with large language models, including fine-tuning, alignment, and structured prompting.
  • Experience building agent-based systems or complex LLM orchestration frameworks (e.g., multi-agent systems, tool-using LLMs, planning modules).
  • Proficiency in Python and modern ML frameworks (PyTorch, JAX, TensorFlow).
  • Experience working with large-scale biomedical datasets (genomics, transcriptomics, clinical records, or scientific corpora).

Preferred

  • Experience designing autonomous research assistants or AI systems that perform multi-step scientific reasoning.
  • Familiarity with knowledge graphs, hybrid symbolic-neural systems, or multimodal foundation models.
  • Understanding of privacy, security, and regulatory considerations in healthcare AI.

Compensation

We offer a competitive compensation and benefits package, seeking to provide an open, flexible, and friendly work environment to empower employees and provide them with a platform to develop their long-term careers. A Summary of Benefits is available for all applicants. We offer a competitive package that includes base salary, bonus, and equity. The base pay range for this position is expected to be $227,000 - $295,000 annually; however, the base pay offered may vary depending on the market, job-related knowledge, skills and capabilities, and experience.
Xaira Therapeutics an equal-opportunity employer. We believe that our strength is in our differences. Our goal to build a diverse and inclusive team began on day one, and it will never end.

TO ALL RECRUITMENT AGENCIES: Xaira Therapeutics does not accept agency resumes. Please do not forward resumes to our jobs alias or employees. Xaira Therapeutics is not responsible for any fees related to unsolicited resumes.