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Biomedical Software Jobs in California (NOW HIRING)

Bachelor's degree or equivalent in engineering or scientific discipline; electrical, mechanical, biomedical, software, systems, or process engineering. * 5 years of quality assurance and quality ...

Bachelor's degree or equivalent in engineering or scientific discipline; electrical, mechanical, biomedical, software, systems, or process engineering. * 5 years of quality assurance and quality ...

Sr. Systems Engineer

San Diego, CA · On-site

$110K - $151K/yr

Bachelor's degree in engineering (Mechanical, Electrical, Biomedical, Software, or related field) * 5+ years of experience in complex system development (medical devices, intraoperative ...

... electrical and software engineers. Lastly, you will be responsible for delivering detailed ... PhD in Biomedical or Optical Engineering. 5+ years of industry experience in related field.

Sr. Systems Engineer

San Diego, CA · On-site

$110K - $151K/yr

Bachelor's degree in engineering (Mechanical, Electrical, Biomedical, Software, or related field) * 5+ years of experience in complex system development (medical devices, intraoperative ...

Biomedical Refrigeration Specialist

Sonora, CA · On-site

$27.75 - $36.75/hr

Biomedical Eng-Ref Lab Work Shift: Day Job Category: Facilities, Environmental Services, and ... Basic computer skills for documentation and navigation of maintenance software and Microsoft Office.

Sr. Systems Engineer

San Diego, CA

$110K - $151K/yr

Bachelor's degree in engineering (Mechanical, Electrical, Biomedical, Software, or related field) * 5+ years of experience in complex system development (medical devices, intraoperative ...

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Biomedical Software information

What is the difference between Biomedical Software vs Biomedical Engineer?

AspectBiomedical SoftwareBiomedical Engineer
Required CredentialsTypically requires a degree in software engineering, computer science, or related fields; certifications in software development are commonRequires a degree in biomedical engineering, electrical engineering, or related fields; licensure or certification may be needed for clinical work
Work EnvironmentPrimarily in software development settings, labs, or healthcare IT departmentsHospitals, research labs, medical device companies, or manufacturing facilities
Employer & Industry UsageTech companies, healthcare IT firms, research institutionsMedical device manufacturers, hospitals, research organizations

Biomedical Software professionals focus on developing and maintaining software solutions used in healthcare, such as electronic health records or medical imaging software. Biomedical Engineers design and improve medical devices and equipment. While both roles work within the healthcare industry, Biomedical Software specialists concentrate on software development, whereas Biomedical Engineers work on hardware and device design.

What does a biomedical software engineer do?

A biomedical software engineer designs, develops, and tests software applications used in healthcare and medical research, such as imaging systems, electronic health records, and diagnostic tools. They often work with programming languages like C++, Java, or Python and collaborate with medical professionals to ensure software meets clinical needs and regulatory standards.

What cities in California are hiring for Biomedical Software jobs?

Cities in California with the most Biomedical Software job openings:

Infographic showing various Biomedical Software job openings in California as of August 2026, with employment types broken down into 1% As Needed, 90% Full Time, 6% Part Time, and 3% Contract. Highlights an 87% Physical, 4% Hybrid, and 9% Remote job distribution.

BioMedical AI Research Engineer

Xaira Therapeutics

South San Francisco, CA

$227K - $295K/yr

Full-time

Re-posted yesterday


Job description

About the Role
We are seeking a Biomedical AI Engineer to design and deploy agentic AI systems that can reason over biomedical knowledge, plan multi-step analyses, and autonomously integrate diverse scientific data sources to accelerate therapeutic discovery.

This role goes beyond traditional LLM + RAG pipelines. You will build AI agents that can retrieve, synthesize, evaluate, and act on biomedical information across literature, omics datasets, and clinical records operating as intelligent systems embedded within discovery workflows.

Key Responsibilities

  • Design and implement agentic AI architectures capable of multi-step reasoning, planning, and tool use in biomedical contexts.
  • Develop LLM-based agents that dynamically retrieve, rank, and synthesize knowledge from scientific literature, knowledge graphs, omics datasets, and clinical data.
  • Build memory and feedback mechanisms that allow agents to refine hypotheses, update context, and adapt to evolving data.
  • Integrate external tools (analysis pipelines, simulation engines, statistical models, databases) into autonomous agent workflows.
  • Architect scalable systems that combine structured and unstructured biomedical data within production-grade AI environments.
  • Collaborate closely with computational biologists, translational scientists, and software engineers to embed agentic systems into real-world discovery pipelines.
  • Evaluate robustness, reliability, and interpretability of autonomous systems in high-stakes biomedical settings.

Qualifications

  • Degree in Computer Science, Machine Learning, Computational Biology, Biomedical Informatics, or related field.
  • Strong hands-on experience with large language models, including fine-tuning, alignment, and structured prompting.
  • Experience building agent-based systems or complex LLM orchestration frameworks (e.g., multi-agent systems, tool-using LLMs, planning modules).
  • Proficiency in Python and modern ML frameworks (PyTorch, JAX, TensorFlow).
  • Experience working with large-scale biomedical datasets (genomics, transcriptomics, clinical records, or scientific corpora).

Preferred

  • Experience designing autonomous research assistants or AI systems that perform multi-step scientific reasoning.
  • Familiarity with knowledge graphs, hybrid symbolic-neural systems, or multimodal foundation models.
  • Understanding of privacy, security, and regulatory considerations in healthcare AI.

Compensation

We offer a competitive compensation and benefits package, seeking to provide an open, flexible, and friendly work environment to empower employees and provide them with a platform to develop their long-term careers. A Summary of Benefits is available for all applicants. We offer a competitive package that includes base salary, bonus, and equity. The base pay range for this position is expected to be $227,000 - $295,000 annually; however, the base pay offered may vary depending on the market, job-related knowledge, skills and capabilities, and experience.
Xaira Therapeutics an equal-opportunity employer. We believe that our strength is in our differences. Our goal to build a diverse and inclusive team began on day one, and it will never end.

TO ALL RECRUITMENT AGENCIES: Xaira Therapeutics does not accept agency resumes. Please do not forward resumes to our jobs alias or employees. Xaira Therapeutics is not responsible for any fees related to unsolicited resumes.