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Bioinformatics Programmer Jobs in Chicago, IL (NOW HIRING)

BiomeSense

Senior Bioinformatics Engineer

Chicago, IL · On-site

$125K - $200K/yr

Senior Bioinformatics Engineer Compensation: $125K - $200K base + 0.25% - 0.5% equity stock options About BiomeSense BiomeSense is a life sciences startup applying gut microbiome (GMB) technologies ...

micro1 AI

Bioinformatics Software Engineer

Naperville, IL · Remote

$80 - $110/hr

Analyze and interpret small-molecule and drug discovery datasets using advanced computational biology, bioinformatics, and cheminformatics methods. * Curate, annotate, and validate chemical and ...

micro1 AI

Bioinformatics Software Engineer

Joliet, IL · Remote

$80 - $110/hr

Analyze and interpret small-molecule and drug discovery datasets using advanced computational biology, bioinformatics, and cheminformatics methods. * Curate, annotate, and validate chemical and ...

micro1 AI

Bioinformatics Software Engineer

Elgin, IL · Remote

$80 - $110/hr

Analyze and interpret small-molecule and drug discovery datasets using advanced computational biology, bioinformatics, and cheminformatics methods. * Curate, annotate, and validate chemical and ...

micro1 AI

Bioinformatics Software Engineer

Aurora, IL · Remote

$80 - $110/hr

Analyze and interpret small-molecule and drug discovery datasets using advanced computational biology, bioinformatics, and cheminformatics methods. * Curate, annotate, and validate chemical and ...

micro1 AI

Bioinformatics Software Engineer

Chicago, IL · Remote

$80 - $110/hr

Analyze and interpret small-molecule and drug discovery datasets using advanced computational biology, bioinformatics, and cheminformatics methods. * Curate, annotate, and validate chemical and ...

Tempus

Bioinformatics Scientist

Chicago, IL · On-site +1

We are seeking a highly motivated and capable Bioinformatics Scientist to join our Liquid Biopsy ... engineers, and product managers to translate cutting-edge research into clinically actionable ...

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All JobsBioinformatics Programmer JobsBioinformatics Programmer Jobs in Chicago, IL

Bioinformatics Programmer information

See Chicago, IL salary details

$71.5K

$144.8K

$257.5K

How much do bioinformatics programmer jobs pay per year?

As of Aug 14, 2026, the average yearly pay for bioinformatics programmer in Chicago, IL is $144,786.00, according to ZipRecruiter salary data. Most workers in this role earn between $97,800.00 and $177,400.00 per year, depending on experience, location, and employer.

What is a bioinformatics programmer?

A Bioinformatics Programmer is a professional who develops and maintains software tools to analyze biological data, such as DNA sequences, protein structures, and genomic variations. They work at the intersection of computer science and biology, using programming languages like Python, R, and Java to process and visualize complex biological datasets. Their role is crucial in fields like genomics, drug discovery, and biomedical research, where they help automate data analysis and support scientific investigations.

What skills and qualifications are needed to be a bioinformatics programmer?

To thrive as a Bioinformatics Programmer, you need strong programming skills (often in Python, R, or Java), a solid background in biology or life sciences, and experience working with large-scale biological data. Commonly used tools and systems include bioinformatics software like BLAST, Bioconductor, cloud computing platforms, and version control systems such as Git, and certifications in relevant domains can be advantageous. Critical thinking, problem-solving, and effective communication are essential soft skills for integrating research findings and collaborating with interdisciplinary teams. These skills ensure you can develop robust, accurate computational solutions that drive advances in biological research and healthcare applications.

What does a bioinformatics programmer do?

A typical day for a Bioinformatics Programmer involves writing and optimizing code to analyze large datasets, commonly derived from genomics, proteomics, or clinical studies. You'll spend time collaborating with biologists, statisticians, and other programmers to design experiments, validate results, and interpret findings. Most roles also include maintaining data pipelines, troubleshooting software issues, and staying updated with the latest bioinformatics tools and research. The work environment often blends independent coding with regular team meetings and project updates, offering both technical and interdisciplinary challenges. This dynamic workflow makes the role both intellectually stimulating and impactful in advancing scientific discoveries.

What are the most commonly searched types of Bioinformatics Programmer jobs in Chicago, IL?

The most popular types of Bioinformatics Programmer jobs in Chicago, IL are:

What are popular job titles related to Bioinformatics Programmer jobs in Chicago, IL?

For Bioinformatics Programmer jobs in Chicago, IL, the most frequently searched job titles are:

What job categories do people searching Bioinformatics Programmer jobs in Chicago, IL look for?

The top searched job categories for Bioinformatics Programmer jobs in Chicago, IL are:

Bioinformatics Programmer jobs near you
Infographic showing various Bioinformatics Programmer job openings in Chicago, IL as of August 2026, with employment types broken down into 82% Full Time, 6% Part Time, 11% Contract, and 1% Nights. Highlights an 88% Physical, 4% Hybrid, and 8% Remote job distribution, with an average salary of $144,786 per year, or $69.6 per hour.

Senior Bioinformatics Engineer

BiomeSense

Chicago, IL • On-site

$125K - $200K/yr

Full-time

Re-posted 23 days ago

Job description

Senior Bioinformatics Engineer
Compensation: $125K – $200K base +  0.25% - 0.5% equity stock options
About BiomeSense
BiomeSense is a life sciences startup applying gut microbiome (GMB) technologies (GutLab, MetaBiome) to advance personalized medicine. We partner with UCSF, UCSD, NIH & the University of Chicago & are backed by LabCorp Ventures, Bluestein Ventures, Seerave Foundation & Emil Capital Partners.
Position
Help build our MetaBiome platform, a software solution for collecting, curating & analyzing longitudinal GMB & health data at scale. Own the infra, pipelines & analytical workflows that turn raw sequencing data into intelligence, with room to grow into a platform leader.
Responsibilities:
  • Bioinformatics Architecture & Infrastructure - design, implement & maintain auditable backend for GMB data from raw shotgun metagenomic sequencing
  • Data Engineering – build & maintain cloud infra: databases, distributed computing workflows & REST endpoints for microbial sequence & clinical metadata
  • Statistical Analysis – Lead design, execution & documentation of reproducible computational experiments end-to-end
  • Methods Development – Develop & implement novel analytical methodologies & algorithms informed by experimental findings & validated via rigorous evaluation
  • Frontend / Backend Development – Design & implement robust data ingestion interfaces leveraging APIs & clinical ontologies, following best practices

Qualifications
Required
  • B.S. /M.S. /PhD in Computational Biology, Bioinformatics or a related field with 3+ yrs industry experience (biotech start-up ideal)
  • Proficiency in Python & JavaScript & experience in production-quality software
  • PostgreSQL or other relational SQL database proficiency
  • Familiarity with clinical ontologies (SNOMED, ICD-11, ATC, LOINC)
  • Familiarity with AWS & best practices in computer security
  • Proficiency with modern frontend web technologies
  • Excellent communication; translates complex scientific concepts to diverse stakeholders
  • Strong ownership mindset & the ability to execute in fast-moving environments
  • Expertise in bioinformatics pipelines, QC & reproducibility

Preferred
  • NGS data experience
  • Familiarity with longitudinal / repeated-measures biological datasets & GMB-specific challenges (compositional data, variability, confounders)
  • Experience integrating ontologies / standardized vocabularies
  • Exposure to cloud infrastructure, workflow orchestration or containerization
  • Interest in AI/ML for large biological datasets

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