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Bioinformatics Programmer Jobs in Chicago, IL (NOW HIRING)

BiomeSense

Senior Bioinformatics Engineer

Chicago, IL · On-site

$125K - $200K/yr

Senior Bioinformatics Engineer Compensation: $125K - $200K base + 0.25% - 0.5% equity stock options About BiomeSense BiomeSense is a life sciences startup applying gut microbiome (GMB) technologies ...

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Moffitt

RESEARCH SOFTWARE ENGINEER

Chicago, IL · On-site

$211K/yr

The Biostatistics & Bioinformatics Shared Resource(BBSR) is seeking a Research Software Engineer to support cancer research by developing reliable, scalable, and reproducible tools. BBSR is a ...

Tempus

Senior Software Engineer II, Data Products

Chicago, IL · On-site

$126K - $166K/yr

You will play a pivotal role in architecting and driving technical strategy for services and APIs that allow bioinformatics scientists, ML and Agent developers to rapidly develop, deploy, and operate ...

Biohub

Computational Biologist

Chicago, IL · On-site

$130K - $163K/yr

PhD in bioinformatics, computer science, statistics, computational biology, biomedical engineering or a related quantitative discipline. * Minimum 2 years of experience in developing bioinformatic ...

Loyola University

Data Scientist

Maywood, IL · On-site

Minimum Education and/or Work Experience Bachelor's degree in data science, statistics, bioinformatics, engineering, or related quantitative field. Programming and data analysis skills and experience.

Loyola University Chicago

Data Scientist

Chicago, IL · On-site

Minimum Education and/or Work Experience Bachelor's degree in data science, statistics, bioinformatics, engineering, or related quantitative field. Programming and data analysis skills and experience.

Biohub

Computational Biologist

Chicago, IL · On-site

$130K - $163K/yr

PhD in bioinformatics, computer science, statistics, computational biology, biomedical engineering or a related quantitative discipline. * Minimum 2 years of experience in developing bioinformatic ...

Lorven Technologies

Neo4j Lead

Mettawa, IL · On-site

S. in Computer Science, Data Science, Bioinformatics, or a related field, with minimum 12+ Years of relevant experience. * Must have 8+ years in software/data engineering with at least 3+ years ...

Saransh Inc

Lead Quality Engineer

Mettawa, IL · On-site

Domain Application · Apply knowledge of Bioinformatics, R&D, Preclinical, and Clinical domains to ... Delivery & Operations · Coordinate with internal delivery, engineering, and support teams. · ...

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All JobsBioinformatics Programmer JobsBioinformatics Programmer Jobs in Chicago, IL

Bioinformatics Programmer information

See Chicago, IL salary details

$71.5K

$144.8K

$257.5K

How much do bioinformatics programmer jobs pay per year?

As of Jul 3, 2026, the average yearly pay for bioinformatics programmer in Chicago, IL is $144,786.00, according to ZipRecruiter salary data. Most workers in this role earn between $97,800.00 and $177,400.00 per year, depending on experience, location, and employer.

What is a Bioinformatics Programmer job?

A Bioinformatics Programmer is a professional who develops and maintains software tools to analyze biological data, such as DNA sequences, protein structures, and genomic variations. They work at the intersection of computer science and biology, using programming languages like Python, R, and Java to process and visualize complex biological datasets. Their role is crucial in fields like genomics, drug discovery, and biomedical research, where they help automate data analysis and support scientific investigations.

What are the key skills and qualifications needed to thrive in the Bioinformatics Programmer position, and why are they important?

To thrive as a Bioinformatics Programmer, you need strong programming skills (often in Python, R, or Java), a solid background in biology or life sciences, and experience working with large-scale biological data. Commonly used tools and systems include bioinformatics software like BLAST, Bioconductor, cloud computing platforms, and version control systems such as Git, and certifications in relevant domains can be advantageous. Critical thinking, problem-solving, and effective communication are essential soft skills for integrating research findings and collaborating with interdisciplinary teams. These skills ensure you can develop robust, accurate computational solutions that drive advances in biological research and healthcare applications.

What does a typical day look like for a Bioinformatics Programmer?

A typical day for a Bioinformatics Programmer involves writing and optimizing code to analyze large datasets, commonly derived from genomics, proteomics, or clinical studies. You'll spend time collaborating with biologists, statisticians, and other programmers to design experiments, validate results, and interpret findings. Most roles also include maintaining data pipelines, troubleshooting software issues, and staying updated with the latest bioinformatics tools and research. The work environment often blends independent coding with regular team meetings and project updates, offering both technical and interdisciplinary challenges. This dynamic workflow makes the role both intellectually stimulating and impactful in advancing scientific discoveries.

What are the most commonly searched types of Bioinformatics Programmer jobs in Chicago, IL? The most popular types of Bioinformatics Programmer jobs in Chicago, IL are:
What are popular job titles related to Bioinformatics Programmer jobs in Chicago, IL? For Bioinformatics Programmer jobs in Chicago, IL, the most frequently searched job titles are:
What job categories do people searching Bioinformatics Programmer jobs in Chicago, IL look for? The top searched job categories for Bioinformatics Programmer jobs in Chicago, IL are:
Bioinformatics Programmer jobs near you
Infographic showing various Bioinformatics Programmer job openings in Chicago, IL as of June 2026, with employment types broken down into 93% Full Time, 6% Part Time, and 1% Nights. Highlights an 82% Physical, 2% Hybrid, and 16% Remote job distribution, with an average salary of $144,786 per year, or $69.6 per hour.
Senior Bioinformatics Engineer

Senior Bioinformatics Engineer

BiomeSense

Chicago, IL • On-site

$125K - $200K/yr

Full-time

Posted 12 days ago

Be an early applicant

Job description

Senior Bioinformatics Engineer
Compensation: $125K – $200K base +  0.25% - 0.5% equity stock options
About BiomeSense
BiomeSense is a life sciences startup applying gut microbiome (GMB) technologies (GutLab, MetaBiome) to advance personalized medicine. We partner with UCSF, UCSD, NIH & the University of Chicago & are backed by LabCorp Ventures, Bluestein Ventures, Seerave Foundation & Emil Capital Partners.
Position
Help build our MetaBiome platform, a software solution for collecting, curating & analyzing longitudinal GMB & health data at scale. Own the infra, pipelines & analytical workflows that turn raw sequencing data into intelligence, with room to grow into a platform leader.
Responsibilities:
  • Bioinformatics Architecture & Infrastructure - design, implement & maintain auditable backend for GMB data from raw shotgun metagenomic sequencing
  • Data Engineering – build & maintain cloud infra: databases, distributed computing workflows & REST endpoints for microbial sequence & clinical metadata
  • Statistical Analysis – Lead design, execution & documentation of reproducible computational experiments end-to-end
  • Methods Development – Develop & implement novel analytical methodologies & algorithms informed by experimental findings & validated via rigorous evaluation
  • Frontend / Backend Development – Design & implement robust data ingestion interfaces leveraging APIs & clinical ontologies, following best practices

Qualifications
Required
  • B.S. /M.S. /PhD in Computational Biology, Bioinformatics or a related field with 3+ yrs industry experience (biotech start-up ideal)
  • Proficiency in Python & JavaScript & experience in production-quality software
  • PostgreSQL or other relational SQL database proficiency
  • Familiarity with clinical ontologies (SNOMED, ICD-11, ATC, LOINC)
  • Familiarity with AWS & best practices in computer security
  • Proficiency with modern frontend web technologies
  • Excellent communication; translates complex scientific concepts to diverse stakeholders
  • Strong ownership mindset & the ability to execute in fast-moving environments
  • Expertise in bioinformatics pipelines, QC & reproducibility

Preferred
  • NGS data experience
  • Familiarity with longitudinal / repeated-measures biological datasets & GMB-specific challenges (compositional data, variability, confounders)
  • Experience integrating ontologies / standardized vocabularies
  • Exposure to cloud infrastructure, workflow orchestration or containerization
  • Interest in AI/ML for large biological datasets

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