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Proteomics Bioinformatics Jobs in Chicago, IL (NOW HIRING)

Integrate proteomics, metabolomics, and related datasets, and explore machine learning or transfer ... PhD in bioinformatics, computer science, statistics, computational biology, biomedical engineering ...

Computational Biologist

Chicago, IL · On-site

$130K - $163K/yr

Integrate proteomics, metabolomics, and related datasets, and explore machine learning or transfer ... PhD in bioinformatics, computer science, statistics, computational biology, biomedical engineering ...

Proteomics Bioinformatics information

See Chicago, IL salary details

$61.3K

$97.3K

$154K

How much do proteomics bioinformatics jobs pay per year?

As of May 28, 2026, the average yearly pay for proteomics bioinformatics in Chicago, IL is $97,322.00, according to ZipRecruiter salary data. Most workers in this role earn between $69,500.00 and $133,400.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Proteomics Bioinformatics Specialist, and why are they important?

To thrive as a Proteomics Bioinformatics Specialist, you need a strong background in molecular biology, biochemistry, and computational analysis, typically supported by an advanced degree in bioinformatics or a related field. Experience with mass spectrometry data analysis tools (such as MaxQuant, Proteome Discoverer), programming languages (like Python or R), and familiarity with protein databases are essential. Critical thinking, problem-solving, and effective communication are standout soft skills for interpreting results and collaborating with interdisciplinary teams. These skills and qualifications are vital for accurately extracting biological insights from complex proteomics data and driving impactful research outcomes.

How does a Proteomics Bioinformatics specialist typically collaborate with experimental biologists and data scientists in research projects?

Proteomics Bioinformatics specialists play a crucial role in interdisciplinary teams by bridging the gap between raw experimental data and biological insights. They frequently work alongside experimental biologists to design experiments and ensure proper data collection, and then partner with data scientists to analyze large-scale proteomic datasets. Effective collaboration includes regular meetings to discuss data interpretation, troubleshooting computational challenges, and integrating findings into broader research objectives. This collaborative environment not only enhances the quality of research but also provides opportunities for professional growth through exposure to cutting-edge technologies and diverse scientific perspectives.

What is proteomics bioinformatics?

Proteomics bioinformatics is a specialized field that combines computational and statistical techniques to analyze and interpret large-scale proteomics data, such as protein identification, quantification, and functional annotation. Professionals in this area develop and use software tools to manage data from experiments like mass spectrometry, helping researchers understand protein functions, interactions, and pathways. The field plays a crucial role in biological research, including disease studies and drug discovery, by making sense of complex protein datasets.

What is the difference between Proteomics Bioinformatics vs Genomics Bioinformatics?

AspectProteomics BioinformaticsGenomics Bioinformatics
Required CredentialsBachelor's or Master's in Bioinformatics, Biology, or related fields; experience with proteomics data analysisBachelor's or Master's in Bioinformatics, Genetics, or related fields; experience with genomic data analysis
Work EnvironmentResearch labs, biotech companies, academic institutions focusing on protein analysisResearch labs, biotech firms, academic settings focusing on DNA/RNA sequencing
Employer & Industry UsagePharmaceuticals, proteomics research, biomarker discoveryGenetics research, personalized medicine, genome sequencing projects

Proteomics Bioinformatics focuses on analyzing protein data, while Genomics Bioinformatics centers on DNA and RNA sequences. Both roles require strong computational skills and biological knowledge but differ in their data types and research applications.

What are popular job titles related to Proteomics Bioinformatics jobs in Chicago, IL? For Proteomics Bioinformatics jobs in Chicago, IL, the most frequently searched job titles are:
What job categories do people searching Proteomics Bioinformatics jobs in Chicago, IL look for? The top searched job categories for Proteomics Bioinformatics jobs in Chicago, IL are:
Infographic showing various Proteomics Bioinformatics job openings in Chicago, IL as of May 2026, with employment types broken down into 88% Full Time, 5% Part Time, 1% Temporary, and 6% Contract. Highlights an 88% Physical, 6% Hybrid, and 6% Remote job distribution, with an average salary of $97,322 per year, or $46.8 per hour.

Computational Biologist

Biohub

Chicago, IL

$130K - $163K/yr

Other

Retirement, PTO

Posted 8 days ago


Job description

The Team

The Biohub is a group of nonprofit research institutes that bring together scientists, engineers, and physicians with the goal of pursuing grand scientific challenges on 10- to 15-year time horizons. The Biohub focuses on understanding underlying mechanisms of disease and developing new technologies that will lead to actionable diagnostics and effective therapies. 

Our Vision

  • We pursue large scientific challenges that cannot be pursued in conventional environments
  • We enable individual investigators to pursue their riskiest and most innovative ideas
  • The technologies developed at the Biohub facilitate research by scientists and clinicians at our home institutions and beyond
    Diversity of thought, ideas, and perspectives are at the heart of Biohub and enable disruptive innovation and scholarly excellence. We are committed to cultivating an organization where all colleagues feel inspired and know their work makes an important contribution.
The Opportunity

The Biohub Chicago is seeking an exceptional Computational Biologist, Spatiotemporal Multi-Omics  to join our growing team. We are looking for a creative and collaborative bioinformatics researcher who is excited to build the analytical foundation for our spatiotemporal multi-omics technology platform.

What You'll Do
  • Develop data analysis workflows for spatiotemporal and multi-omics datasets. 
  • Build visualization tools that enable exploration and interpretation of complex biological data across space and time. 
  • Integrate proteomics, metabolomics, and related datasets, and explore machine learning or transfer learning approaches to support biological discovery.
  • Collaborate closely with experimental scientists, communicate findings clearly, and contribute to publications, presentations, and open-source software as appropriate.
What You'll Bring
  • PhD in bioinformatics, computer science, statistics, computational biology, biomedical engineering or a related quantitative discipline. 
  • Minimum 2 years of experience in developing bioinformatic methods, analysis pipelines, or software tools for biological data using appropriate programming language.
  • Minimum of 1 year of experience in at least one of the following areas: spatial data analysis, multi-omics integration, or machine learning for biological applications.
  • A strong record of research productivity, including publications, open-source contributions, or both.
  • A collaborative mindset, strong communication skills, and enthusiasm for working closely with wet-lab teams.

(Preferred)

  • 1+ year of experience with imaging mass spec (e.g., MALDI)
  • 1+ year of experience with single-cell proteomics and/or metabolomics
  • 1+ year of experience building visualization tools, or scientific software.
Compensation

The Chicago, IL  base pay range for a new hire in this role is $130,000 - $163,000. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process. 

This position may be eligible to participate in our discretionary annual performance bonus program. Bonus eligibility and targets are determined in accordance with our total rewards philosophy and may vary by role.

Better Together

As we grow, we're excited to strengthen in-person connections and cultivate a collaborative, team-oriented environment. This role is a hybrid position requiring you to be onsite for at least 60% of the working month, approximately 3 days a week, with specific in-office days determined by the team's manager. The exact schedule will be at the hiring manager's discretion and communicated during the interview process.

Benefits for the Whole You 

We're thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible. 

  • Provides a generous employer match on employee 401(k) contributions to support planning for the future.
  • Paid time off to volunteer at an organization of your choice. 
  • Funding for select family-forming benefits. 
  • Relocation support for employees who need assistance moving

If you're interested in a role but your previous experience doesn't perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.

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