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Biocatalysis Jobs (NOW HIRING)

Codexis

Principal Process Engineer

Redwood City, CA · On-site

Expertise in flow chemistry, biocatalysis, or oligonucleotide synthesis technologies (e.g., SPOS, enzymatic platforms). Demonstrated leadership in scaleup activities, including tech transfer of ...

The Pennsylvania State University

... biocatalysis and synthetic chemistry. Applicants must have a Ph.D. in chemistry. Candidates with expertise in organic synthesis, enzyme studies, or related areas are especially encouraged to apply.

Codexis Inc

Principal Process Engineer

Plano, TX · On-site

$165K - $185K/yr

S. with 8+ years. • Expertise in flow chemistry, biocatalysis, or oligonucleotide synthesis technologies (e.g., SPOS, enzymatic platforms). • Demonstrated leadership in scale‑up activities ...

Codexis, Inc.

Principal Process Engineer

Redwood City, CA · On-site

$165 - $185/hr

Expertise in flow chemistry, biocatalysis, or oligonucleotide synthesis technologies (e.g., SPOS, enzymatic platforms). * Demonstrated leadership in scale‑up activities, including tech transfer of ...

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How much do biocatalysis jobs pay per hour?

As of Aug 16, 2026, the average hourly pay for biocatalysis in the United States is $22.53, according to ZipRecruiter salary data. Most workers in this role earn between $18.27 and $24.28 per hour, depending on experience, location, and employer.

What is biocatalysis?

Biocatalysis refers to the use of natural catalysts, such as enzymes or whole cells, to accelerate chemical reactions. It is widely used in industries like pharmaceuticals, food, and biofuels to create more efficient, selective, and environmentally friendly processes compared to traditional chemical methods. Biocatalysis can offer advantages such as mild reaction conditions, high specificity, and reduced need for hazardous chemicals. Researchers and companies use biocatalysis to develop sustainable and cost-effective production methods for a variety of products.

What are the key skills and qualifications needed to thrive as a biocatalysis scientist, and why are they important?

To thrive as a Biocatalysis Scientist, you need a solid background in biochemistry, enzymology, and organic chemistry, typically with an advanced degree in a relevant scientific field. Experience with analytical techniques like HPLC, GC-MS, and protein engineering tools, as well as familiarity with laboratory information management systems (LIMS), is commonly required. Strong problem-solving skills, attention to detail, and effective teamwork are essential soft skills for this role. These competencies are crucial for optimizing enzyme-catalyzed reactions and driving innovation in sustainable chemical processes.

What are the common collaborative interactions for a biocatalysis professional within a research or industrial setting?

Biocatalysis professionals frequently work in multidisciplinary teams, collaborating with chemists, microbiologists, process engineers, and analytical scientists. They often participate in project meetings to discuss experimental results, troubleshoot challenges, and design new enzyme-based processes. These interactions are essential for integrating biocatalytic steps into larger workflows, optimizing reaction conditions, and ensuring that scale-up considerations are addressed early in development. Effective communication and teamwork are key to successfully advancing biocatalysis projects from research to application.
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Biocatalysis jobs near you
Infographic showing various Biocatalysis job openings in the United States as of August 2026, with employment types broken down into 100% Full Time. Highlights an 90% In-person, and 10% Remote job distribution, with an average salary of $46,864 per year, or $22.5 per hour.

Senior Scientist, Upstream Process Development

Stylus Medicine

Cambridge, MA • On-site

$155K - $170K/yr

Full-time

Re-posted 11 days ago

Job description

About Stylus Medicine:
Stylus Medicine is developing transformative in vivo genetic medicines to unlock cures. Stylus combines engineered recombinases with non-viral delivery to specifically encode therapeutics. The company's approach is versatile and modular, with potential therapeutic application across oncology, autoimmune, genetic diseases, and beyond.
About the Role:
Stylus Medicine is seeking an intellectually curious and collaborative Senior Scientist, who will lead the development of upstream microbial fermentation processes as part of our CMC Tech Ops team. This role will be responsible for process definition, development, characterization, scale-up and tech transfer from bench scale to pilot. Working closely with the Research, Preclinical, and Formulation teams, this is a special opportunity to advance the development of transformative in vivo genetic medicines.
Key Responsibilities & Accountabilities:
  • Develop scalable production processes for nucleic acids and recombinant proteins
  • Leverage expertise in fermentation and mammalian cell culture to design, optimize, scale-up and characterize production processes
  • Independently utilize multivariate design of experiment (DoE) approaches to improve productivity and optimize parameters for product quality
  • Drive fermentation platform development and new technology implementation to improve process performance, generation of predictive process models, and enhance process control and robustness
  • Design and implement in-process analytics to improve productivity while reducing process and product derived impurities
  • Maintain and troubleshoot equipment to ensure consistency and continuity of operations
  • Document, analyze and present experimental results internally and externally
  • Partner with CDMOs and provide technology transfer support to facilitate scale up
  • Interface with cross-functional teams to ensure programs are on track and stakeholders' needs are met
  • Maintain accurate and reliable record keeping including database management, batch records, notebooks, and all other pertinent documentation

Qualifications & Skills:
  • PhD in Chemical/Biomedical Engineering, Biochemistry, Pharmaceutical Sciences, or related discipline with >4 years of experience, or BS/MS with >8 years of experience in biopharmaceutical or biotechnology development, including experience in developing scalable fermentation processes for producing plasmid DNA and/or recombinant products
  • In-depth experience and knowledge in fermentation process development, optimization, and process scale-up / scale-down model development
  • Familiarity with strain engineering and biocatalysis
  • Familiarity with performing operations in a cleanroom environment, applying controls to ensure aseptic processing
  • Demonstrated ability to coach and mentor junior researchers
  • Independently motivated and good problem-solving ability
  • Attention to detail and accuracy in developing, reviewing, and following protocols, SOPs, batch records and technology transfer documents is a must
  • Demonstrated ability to work collaboratively across teams to meet project deliverables and timelines
  • Strong communication, decision-making and organizational skills
  • Proficiency with statistical analysis software (e.g., JMP) is highly desired
  • Prior experience partnering with external CDMOs and conducting tech transfers preferred

Pay Range: $155,000 - $170,000

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