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Biocatalysis Jobs (NOW HIRING)

Integrated Resources INC

Organic Chemist

Groton, CT

Job Role- The biocatalysis chemist will work with the team to develop and operationalize standard biocatalysis screening process (platforms) to support the Integrated Oxidative Platform (IOP) for ...

Pfizer

Senior Scientist, Process Development

Groton, CT

$93K - $156K/yr

This position sits within the Biocatalysis Center of Excellence in the Technology API group and serves as both a laboratory-based experimentalist and subject matter expert. The role will focus on ...

MaverickX

Head of Product, PetroX

Austin, TX · On-site

$231K - $241K/yr

... biocatalysis, or other emerging chemical technologies in the oilfield • Technical proficiency with business and analytical tools (Excel, PowerPoint, HubSpot, Python, SQL, Tableau, Cursor) Company

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How much do biocatalysis jobs pay per hour?

As of Jul 3, 2026, the average hourly pay for biocatalysis in the United States is $22.53, according to ZipRecruiter salary data. Most workers in this role earn between $18.27 and $24.28 per hour, depending on experience, location, and employer.

What is biocatalysis?

Biocatalysis refers to the use of natural catalysts, such as enzymes or whole cells, to accelerate chemical reactions. It is widely used in industries like pharmaceuticals, food, and biofuels to create more efficient, selective, and environmentally friendly processes compared to traditional chemical methods. Biocatalysis can offer advantages such as mild reaction conditions, high specificity, and reduced need for hazardous chemicals. Researchers and companies use biocatalysis to develop sustainable and cost-effective production methods for a variety of products.

What are the key skills and qualifications needed to thrive as a Biocatalysis Scientist, and why are they important?

To thrive as a Biocatalysis Scientist, you need a solid background in biochemistry, enzymology, and organic chemistry, typically with an advanced degree in a relevant scientific field. Experience with analytical techniques like HPLC, GC-MS, and protein engineering tools, as well as familiarity with laboratory information management systems (LIMS), is commonly required. Strong problem-solving skills, attention to detail, and effective teamwork are essential soft skills for this role. These competencies are crucial for optimizing enzyme-catalyzed reactions and driving innovation in sustainable chemical processes.

What are the common collaborative interactions for a biocatalysis professional within a research or industrial setting?

Biocatalysis professionals frequently work in multidisciplinary teams, collaborating with chemists, microbiologists, process engineers, and analytical scientists. They often participate in project meetings to discuss experimental results, troubleshoot challenges, and design new enzyme-based processes. These interactions are essential for integrating biocatalytic steps into larger workflows, optimizing reaction conditions, and ensuring that scale-up considerations are addressed early in development. Effective communication and teamwork are key to successfully advancing biocatalysis projects from research to application.
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What states have the most Biocatalysis jobs? States with the most job openings for Biocatalysis jobs include:
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Biocatalysis jobs near you
Infographic showing various Biocatalysis job openings in the United States as of June 2026, with employment types broken down into 100% Full Time. Highlights an 100% Physical job distribution, with an average salary of $46,864 per year, or $22.5 per hour.
Senior Director, Biocatalysis

Senior Director, Biocatalysis

Alnylam Pharmaceuticals

Cambridge, MA • On-site

$229K - $310K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 23 days ago

Job description

Overview:
We are seeking a Head of Biocatalysis to lead the discovery, engineering, development, and implementation of enzyme-enabled technologies across our portfolio. This individual will define the company's biocatalysis strategy, build internal protein screening and engineering capabilities, and partner with external organizations to discover and develop new and improved enzymes.
The role will focus on protein discovery, enzyme engineering, enzyme and reaction screening, protein design, expression, purification, characterization, and scalable biocatalytic process development. The Head of Biocatalysis will evaluate opportunities for biocatalyst substitution and new chemistry, including new and improved biocatalytic syntheses of oligonucleotides and applications for small molecule processes.
The successful candidate will bring deep expertise in biocatalysis and protein engineering, strong process development judgment, and the ability to partner across Drug Product, Starting Materials, Process Chemistry, CMC, Manufacturing, Quality, Regulatory, and external collaborators to deliver robust, scalable, and impactful biocatalytic solutions.
This position is onsite and will be primarily located in Cambridge, MA.
Responsibilities:
  • Develop and lead the biocatalysis strategy across starting materials, oligonucleotides, and small molecule processes.
  • Identify high-impact opportunities for biocatalyst substitution, new enzymatic chemistry, and improved synthetic routes.
  • Lead enzyme discovery, engineering, screening, and optimization through internal capabilities and external partnerships.
  • Establish internal protein screening and engineering capabilities, including protein design, expression, purification, characterization, and reaction screening.
  • Drive biocatalytic applications for oligonucleotide synthesis and small molecule process development.
  • Partner with Process Chemistry, CMC, Manufacturing, Quality, and Regulatory teams to translate biocatalytic concepts into scalable, robust, and manufacturable processes.
  • Manage strategic collaborations with academic institutions, CROs/CDMOs, and enzyme discovery or engineering companies.
  • Evaluate emerging technologies and external opportunities in biocatalysis, protein engineering, and biocatalyst manufacturing.
  • Serve as the technical authority for biocatalysis, providing scientific guidance, risk assessments, and recommendations to senior stakeholders.

Qualifications:
  • PhD in Biochemistry, Chemistry, Chemical Engineering, Molecular Biology, Enzymology, Biochemical Engineering, Protein Engineering, or a related discipline.
  • Minimum 12 years of relevant experience in biocatalysis, enzyme engineering, protein discovery, process chemistry, or biochemical process development within pharmaceutical, biotechnology, CDMO, or industrial settings.
  • Demonstrated experience discovering, engineering, screening, or implementing enzymes for synthetic or manufacturing applications.
  • Strong technical understanding of Enzyme and reaction screening; Protein design and engineering; Protein expression, purification, and characterization; Biotransformation and enzyme-enabled synthesis; Process development, scale-up, and technology transfer.
  • Experience evaluating external technologies and managing collaborations with academic institutions, CROs, CDMOs, or biotechnology companies.
  • Ability to operate effectively across early discovery, development, manufacturing, and CMC environments.
  • Strong communication, influencing, and cross-functional leadership skills.

#LI-KB1 #LI-Onsite
U.S. Pay Range
$229,500.00 - $310,500.00
The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity).
Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together.
Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers
About Alnylam
We are the leader in RNAi therapeutics - a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another.
At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

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