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Associate Downstream Processing Scientist Jobs (NOW HIRING)

Sr. Downstream Processing Technician

Saint Louis, MO

$30/hr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Downstream Processing Technician III Are you ready to take your career in manufacturing to the next ... As a leading company in the scientific research industry, we are dedicated to enabling our ...

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Associate Downstream Processing Scientist information

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$18

$35

$57

How much do associate downstream processing scientist jobs pay per hour?

As of Aug 14, 2026, the average hourly pay for associate downstream processing scientist in the United States is $35.92, according to ZipRecruiter salary data. Most workers in this role earn between $27.88 and $40.87 per hour, depending on experience, location, and employer.

What is the difference between Associate Downstream Processing Scientist vs Associate Upstream Processing Scientist?

AspectAssociate Downstream Processing ScientistAssociate Upstream Processing Scientist
Primary FocusPurification and recovery of bioproductsCell culture and fermentation processes
Skills & CertificationsProtein purification, chromatography, GMP complianceCell culture, bioreactor operation, aseptic techniques
Work EnvironmentLaboratories, manufacturing facilitiesBioreactors, cell culture labs
Industry UsageBiotech, pharmaceutical manufacturingBiotech, pharmaceutical research and production

Both roles are essential in biopharmaceutical production, with the Associate Downstream Processing Scientist focusing on purification processes, while the Associate Upstream Processing Scientist handles cell growth and fermentation. They often collaborate within the same production pipeline, but their skill sets and daily tasks differ based on their specific focus areas.

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Infographic showing various Associate Downstream Processing Scientist job openings in the United States as of August 2026, with employment types broken down into 1% As Needed, 68% Full Time, 28% Part Time, 1% Temporary, and 2% Contract. Highlights an 97% Physical, 1% Hybrid, and 2% Remote job distribution, with an average salary of $74,723 per year, or $35.9 per hour.

Sr. Research Associate, Process Development Downstream

Avid Bioservices

Tustin, CA

$72K - $91K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 22 days ago


Job description

Looking to join a passionate team dedicated to developing and manufacturing life-saving biopharmaceuticals? Avid Bioservices is a leading clinical and commercial biologics CDMO focused on creating innovative solutions to meet the needs of our clients and improve patient outcomes.
Your Role:
The Senior Research Associate, Process Development Downstream will provide laboratory support for Process Development by leading in the downstream process and/or method development. The Senior Research Associate may be assigned various tasks within the department and outside the department as needed.
Key Responsibilities:

  • Serve as a subject matter expert (SME) and/or technical lead for downstream process development and purification of monoclonal antibodies, recombinant proteins, and related biologics. Responsibilities include buffer formulation and preparation, chromatography process development and optimization, filtration development, and routine process execution.
  • Lead downstream process development studies, including chromatography screening, process optimization, and scale-up activities to support client programs from early development through commercialization.
  • Perform and oversee in-process and routine analytical testing to support downstream development activities, including protein concentration determination (A280), HPLC-based assays, and other relevant analytical methods.
  • Independently execute downstream unit operations using chromatography systems, filtration equipment, and associated process analytical tools with minimal supervision.
  • Support process scale-up, technology transfer, and manufacturing operations by developing robust buffer preparation strategies and downstream processing workflows suitable for pilot and GMP manufacturing environments.
  • Compile, analyze, interpret, and present experimental data. Author technical reports, development summaries, protocols, and client-facing documentation, and present findings during internal project reviews and client meetings.
  • Lead troubleshooting and continuous improvement initiatives to enhance process performance, robustness, productivity, and scalability.
  • Contribute to the evaluation, implementation, and validation of emerging technologies, process analytics, laboratory automation platforms, and process intensification strategies to improve development efficiency.
  • Experience with laboratory automation, process intensification, process analytical technologies (PAT), high-throughput process development, and data analytics is highly desirable.
  • Mentor junior scientists and provide technical guidance across downstream process development activities.
  • Perform other duties and project-related responsibilities as assigned.

Minimum Qualifications:

  • Bachelor's degree with 3-4 years of relevant biopharmaceutical industry experience, or a Master's degree in Chemical Engineering, Biochemical Engineering, Biotechnology, Biological Sciences, or a related field.
  • Candidates should possess a strong understanding of downstream processing principles, experimental design, data analysis, and bioprocess development methodologies.

Position Type/Expected Hours of Work:

This role is a full-time onsite position. Days and hours of work are Monday through Friday unless otherwise stated by Supervisor. The employee must also have the ability to work overtime and/or weekends when necessary.

Compensation:

We offer competitive compensation packages for this role, including a base salary, performance-based bonuses, and comprehensive benefits such as health, dental, and vision insurance, 401(k) matching, and paid time off.

The compensation range for this role is $72,800 - $91,000 annually depending on experience and qualifications. Additionally, we offer opportunities for career growth and development as well as a supportive and inclusive work environment.

Who you are:

  • You have a "bring it on!" team player approach and an unshakable positive attitude, always ready to tackle anything that comes your way.
  • Your written and verbal skills are out of this world, and you communicate with clarity and confidence.
  • You have exceptional multitasking skills and an unparalleled attention to detail that ensure the smooth running of everything.
  • You are a master at building relationships, capable of establishing connections with anyone, be it team members, clients, vendors, or suppliers.

Physical Demands & Work Environment:

In this dynamic role, expect a blend of regular activities like sitting, standing, and walking, with occasional physically engaging tasks such as lifting objects up to 25 pounds. The work environment might expose you to electrical shocks, toxic chemicals, vibrations, or loud noise levels occasionally. However, reasonable accommodations are available to enable individuals with different abilities to perform effectively, ensuring a supportive and adaptable work setting. Your visual acuity, including close, distance, and color vision, will be essential in navigating through the diverse day-to-day demands of this position.

Employment Type: Full-Time