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Associate Downstream Processing Scientist Jobs (NOW HIRING)

Legend Biotech USA, Inc.

The successful candidate will drive scientific excellence in downstream processing (DSP)-including clarification, chromatography, TFF, sterile filtration and fill/finish-ensuring processes are robust ...

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Associate Downstream Processing Scientist information

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How much do associate downstream processing scientist jobs pay per hour?

As of Jul 24, 2026, the average hourly pay for associate downstream processing scientist in the United States is $35.92, according to ZipRecruiter salary data. Most workers in this role earn between $27.88 and $40.87 per hour, depending on experience, location, and employer.

What is the difference between Associate Downstream Processing Scientist vs Associate Upstream Processing Scientist?

AspectAssociate Downstream Processing ScientistAssociate Upstream Processing Scientist
Primary FocusPurification and recovery of bioproductsCell culture and fermentation processes
Skills & CertificationsProtein purification, chromatography, GMP complianceCell culture, bioreactor operation, aseptic techniques
Work EnvironmentLaboratories, manufacturing facilitiesBioreactors, cell culture labs
Industry UsageBiotech, pharmaceutical manufacturingBiotech, pharmaceutical research and production

Both roles are essential in biopharmaceutical production, with the Associate Downstream Processing Scientist focusing on purification processes, while the Associate Upstream Processing Scientist handles cell growth and fermentation. They often collaborate within the same production pipeline, but their skill sets and daily tasks differ based on their specific focus areas.

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Associate Downstream Processing Scientist jobs near you
Infographic showing various Associate Downstream Processing Scientist job openings in the United States as of July 2026, with employment types broken down into 1% As Needed, 69% Full Time, 28% Part Time, 1% Temporary, and 1% Contract. Highlights an 97% Physical, 1% Hybrid, and 2% Remote job distribution, with an average salary of $74,723 per year, or $35.9 per hour.

Senior Manufacturing Associate, Downstream

Bora Biologics

San Diego, CA

$75K - $90K/yr

Other

Posted 29 days ago

Job description

Description

SUMMARY


Under general supervision, the Senior Manufacturing Associate, Downstream, will perform routine manufacturing activities in GMP manufacturing areas including purification and the associated sub-processes/ preparation. Operations will be performed according to Standard Operating Procedures (SOPs) and batch records. Perform manufacturing steps, execute routine batch records, and revise documents such as batch records and SOPs as needed. Drives projects and assignments and provides mentorship to associates. Flexible shift schedule and overtime may be required.


JOB RESPONSIBILITIES


Technical:

? Perform moderately complex tasks using defined protocols or procedures which contribute to the achievement of project milestones.

? Perform GMP manufacturing activities in assigned areas.

? Set-up, operate, maintain and clean downstream bioprocessing equipment, which includes but is not limited to chromatography systems, UF/DF and Viral filtration skids and mixers.

? Perform basic troubleshooting of bioprocess equipment.

? Perform manual cleaning and sterilization of manufacturing areas, parts and components.

Compliance:

? Follow Standard Operating Procedures (SOPs), current Good Manufacturing Practices (cGMPs), plant safety guidelines and other established procedures during the manufacturing process to produce quality products.

? Accurately complete and maintain detail-oriented process-related documentation of equipment logs and batch records following the manufacturing Good Documentation Practices (GDP).

? Draft and revise SOPs and batch records.

Teamwork and Communication:

? Participate in regularly scheduled team meetings to discuss ideas, troubleshoot issues, go over lessons learned and identify future projects or tasks.

? May provide mentoring and coaching to colleagues, team members, or those with similar or less experience

? Act as Lead when Specialist/Supervisor is unavailable.

? Address production issues and report any compliance related concerns to supervisor and/or management as soon as possible.

? Fosters teamwork and is expected to suggest project improvements.


JOB REQUIREMENTS


Education and Experience


? Advanced degree in life sciences or related discipline with 3 years of experience in the pharmaceutical or biotech industry, or equivalent education and experience.

? Bachelor's degree with 6 years of experience in the pharmaceutical or biotech industry, or equivalent education and experience.

? High School Diploma/GED with 8 years of experience in the pharmaceutical or biotech industry, or equivalent education and experience.


Knowledge, Skills and Abilities:


? Downstream/Purification experience and skills in Protein Chromatography, TFF, Depth Filtration, Viral Filtration, Bulk Drug Substance Formulation, and Final Filtration. Aseptic Sampling of process pools and buffers. Buffer Preparation, Tubing assemblies and Autoclaving Operations.

? Knowledge of UNICORN and Common Control Platform (CCP) Software is preferred.

? Fundamental knowledge of current biologics regulations and cGMP for drug substance operation.

? Proficient with Microsoft Word and Excel.

? Able to work with pressurized systems, steam, and corrosive chemicals with necessary safety precautions.

? Demonstrated ability to follow and document activities in written procedures and/or logbooks.

? Detail-oriented, strong team player.

? Effective collaboration skills and the ability to work cross functionally across categories and internal stakeholders.

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