Principal Scientist – Process Chemistry
Coventry, RI
Summary
We are seeking an experienced and collaborative Principal Scientist to lead complex chemical development programs within a fast-paced Process Chemistry environment. This role provides scientific leadership across multidisciplinary project teams, supporting API development for GLP toxicology studies and GMP clinical manufacturing while delivering high-quality solutions to clients.
The successful candidate will combine strong technical expertise in synthetic/process chemistry with leadership, mentoring, and client-facing responsibilities.
Key Responsibilities
- Lead and design experimental programs to solve complex chemical development challenges for client projects and internal initiatives.
- Apply advanced process chemistry and retrosynthetic analysis expertise to support API development and process optimization.
- Plan, execute, document, and report experimental work in compliance with applicable GxP, ICH, GMP, and company standards.
- Serve as a scientific leader and mentor to junior scientists and cross-functional project teams.
- Manage and support multiple client projects, including project leadership, reporting, technical discussions, and delivery of project milestones.
- Support technology transfer activities and mixed-model projects across the organization.
- Build strong client relationships, host client visits, and support internal and external audits.
- Stay current with emerging scientific technologies and apply innovative approaches to process chemistry challenges.
- Promote a strong quality culture, collaboration, safety, and continuous improvement within the department.
- Maintain accurate training records and ensure compliance with all safety, procedural, and environmental requirements.
Qualifications
Required
- PhD in Chemistry or related scientific discipline OR
- MSc/BSc in Chemistry or related field with significant relevant industry experience
Experience & Technical Skills
- Strong academic and/or industrial achievements in process chemistry or chemical development
- Demonstrated experience solving complex chemical development problems
- Expertise in retrosynthetic analysis and advanced laboratory techniques/instrumentation
- Experience supporting API drug development within regulated environments
- Proven ability to contribute effectively within multidisciplinary scientific teams
- Prior team leadership or people management experience preferred
- Experience working within GMP and/or GLP environments strongly preferred
Key Competencies
- Strong scientific leadership and mentoring capabilities
- Excellent organizational and project management skills
- Strong written and verbal communication abilities
- Exceptional attention to detail and problem-solving skills
- Ability to manage multiple priorities in a fast-paced environment
- Collaborative mindset with strong client-facing professionalism
- Solid computer and technical documentation skills
Compensation ranges depending on Associate or Principal requirements:
Principal Scientist $140k -$170k
Associate Principal Scientist $130k -$160k
Additional Information
This role requires strict adherence to company policies, SOPs, environmental health and safety procedures, and confidentiality standards. The successful candidate will help foster a transparent, collaborative, and quality-driven culture focused on delivering high-quality products and services while maintaining the highest professional and ethical standards.