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Assistant Vector Biology Jobs (NOW HIRING)

Managed Staffing

Purification Scientist

Boston, MA · On-site

$44 - $46/hr

This role will support purification and characterization of viral vectors, biologics, or ... practices * Assist with troubleshooting and optimization of purification processes * Analyze ...

Harris County, TX

Vector Surveillance Technician

Houston, TX · On-site

$20 - $24.50/hr

... * Assist in the development, preparation, use, and maintenance of field surveillance material and ... Knowledge of arthropod biology and habitats, morphological identification, integrated vector ...

Harris County

Vector Surveillance Technician

Houston, TX · On-site

$41K/yr

... Assist in the development, preparation, use, and maintenance of field surveillance material and ... Knowledge of arthropod biology and habitats, morphological identification, integrated vector ...

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Assistant Vector Biology information

What is the difference between Assistant Vector Biology vs Laboratory Technician?

AspectAssistant Vector BiologyLaboratory Technician
Required CredentialsBachelor's degree in biology, entomology, or related fieldAssociate's degree or certification in laboratory techniques
Work EnvironmentFieldwork, research labs, vector control programsLaboratories, research facilities, clinical settings
Employer & IndustryPublic health agencies, research institutions, vector control programsHospitals, research labs, biotech companies
Common Search & ComparisonYesYes

The Assistant Vector Biology role primarily involves fieldwork and research related to disease-carrying vectors, requiring a background in biology or entomology. Laboratory Technicians focus on conducting experiments and maintaining lab equipment in clinical or research settings. While both roles support scientific research, Assistant Vector Biology positions often include field activities, whereas Laboratory Technicians work mainly indoors in labs.

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Senior Scientist, Viral Vector Process Development, Downstream

Senior Scientist, Viral Vector Process Development, Downstream

AstraZeneca

Gaithersburg, MD • On-site

$98K - $135K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 24 days ago

AstraZeneca rating

8.4

Company rating: 8.4 out of 10

Based on 44 frontline employees who took The Breakroom Quiz

18th of 74 rated pharmaceutical

Job description

AstraZeneca is looking for a highly motivated and experienced Senior Scientist, Viral Vector Process Development (Downstream). The candidate will play a critical role in building and leading a high-performing team that accelerates AstraZeneca's emerging Cell Therapy modalities portfolio. You will design, execute, and optimize scalable Lentiviral Vector (LVV) downstream purification processes with a primary focus on clinical and commercial scales. You will contribute hands-on to experimental design, process characterization, and scale-up/tech transfer activities from research through INDenabling, partnering closely with Research, Analytical Development, CMC, Regulatory, Manufacturing, Quality, and external CDMOs. This position is based in Gaithersburg, MD.
Key Responsibilities
  • Downstream Process Development: Plan and perform experiments to develop scalable, cost-effective LVV purification processes for ex vivo and in vivo applications, targeting yield, purity, potency, and consistency.

  • Unit Operations Execution: Execute and optimize clarification, chromatography, UF/DF/TFF, sterile filtration, and formulation/fill-related steps; define phase-appropriate in-process controls and operating ranges.

  • Process Characterization & Data Analysis: Design and analyze studies (including DOE) to identify CPPs/CMAs, establish design space, and justify control strategies; trend performance, conduct troubleshooting and root cause analysis, and recommend corrective actions.

  • Scale-Up, Scale-Down & Tech Transfer Support: Develop representative scale-down models; support scale-up to pilot, clinical, and commercial-relevant equipment; prepare technical transfer documents and assist transfers to internal GMP sites and CDMOs.

  • Novel Technologies & Continuous Improvement: Evaluate and implement next-generation purification technologies and consumables to improve efficiency, robustness, and product quality; contribute to continuous improvement initiatives.

  • Documentation & Compliance: Author high-quality protocols, reports, batch records, and development summaries; support drafting of CMC content for regulatory submissions (e.g., IND) and align practices with cGMP and Quality systems expectations.

  • Cross-Functional Collaboration: Partner with upstream PD and Analytical Development to link process parameters with product quality attributes (e.g., titer, infectivity/potency, residuals/impurities); collaborate with Manufacturing and Quality on operational feasibility and compliance.

Qualifications
  • Education: Ph.D. in Chemical Engineering, Biochemical Engineering, Biotechnology, or related field with 1+ years of industry experience; OR M.S. with 4+ years; OR B.S. with 5+ years of hands-on industry experience.

  • Experience: Hands-on downstream process development for LVV (preferred) or other viral vectors/biologics; familiarity with clinical/commercial scale considerations and tech transfer.

  • Technical Expertise: Practical proficiency in clarification, chromatography, UF/DF/TFF, sterile filtration, and formulation; understanding of viral vector-specific impurity profiles (host cell proteins/DNA, process residuals) and strategies to control them.

  • Data & Risk Tools: Working knowledge of statistical analysis and DOE; familiarity with QbD principles, risk assessments (e.g., FMEA), and process justification.

  • GMP & Regulatory: Understanding of cGMP and Quality systems; familiarity with FDA/EMA guidance relevant to gene and cell therapy; experience contributing to CMC sections of regulatory filings is a plus.

  • Communication & Collaboration: Strong written and verbal communication; ability to work effectively in cross-functional, matrixed teams; demonstrated problem-solving and troubleshooting skills.

Preferred Qualifications
  • Experience scaling LVV or other viral vector/biologic purification processes from preclinical to clinical/commercial-relevant equipment and consumables.

  • Experience supporting tech transfer and implementation at internal sites and CDMOs.

  • Exposure to PAT/digital tools for process monitoring and data integrity; experience with knowledge management systems.

  • Demonstrated innovation in evaluating/implementing next-generation purification technologies.

At AstraZeneca, we are at the forefront of innovation with constant new products and launches. Our dynamic environment encourages collaboration and problem-solving as we strive to deliver life-changing medicines. We embrace challenges in rapidly changing markets by continuously seeking better ways to deliver medicines to patients. Our team is diverse and connected globally, working together to push the boundaries of supply chain excellence. With a focus on sustainability and a commitment to doing things the right way, we offer opportunities for growth and development in a supportive environment.
Join us in making a difference-apply today!
The annual base pay for this position ranges from $108,473.60 - $162,710.40. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an "at-will position" and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.
Date Posted
29-Jun-2026
Closing Date
16-Jul-2026
Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

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