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Antibody Spr Jobs (NOW HIRING)

Sr Scientist, Antibody Discovery

Quincy, MA · On-site

$96K - $131K/yr

Sr Scientist, Antibody Discovery (onsite in Quincy, MA) This is an individual contributor role that ... Previous experience with Carterra SPR systems, Octet BLI, and/or developability assays (HPLC and ...

Sr Scientist, Antibody Discovery

Quincy, MA · On-site

$96K - $131K/yr

Guide multiple projects per day to ensure scientific excellence and execution for antibody projects involving binding affinity determination (SPR, BLI) and developability assays (i.e. aSEC, CIC, HIC ...

Senior Scientist

Durham, NC · On-site

$80K - $167K/yr

Strong understanding of antibody biophysical characterization and developability considerations * Ability to operate, maintain, and troubleshoot complex SPR instrumentation independently * Excellent ...

Senior Research Scientist

Philadelphia, PA · On-site

$99K - $126K/yr

... SPR, and other analytical assays. * Establish and applyprotein and antibody quality-control criteriato ensure samples are suitable for structural studies, binding assays, biochemical assays ...

Senior Research Scientist

Wilmington, DE · On-site

$95K - $121K/yr

... SPR, and other analytical assays. * Establish and apply protein and antibody quality-control criteria to ensure samples are suitable for structural studies, binding assays, biochemical assays ...

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Showing results 1-20

Antibody Spr information

What is an antibody spr?

Antibody SPR jobs involve working with Surface Plasmon Resonance (SPR) technology to analyze antibody interactions, such as binding kinetics and affinity. Professionals in these roles often perform experiments using SPR instruments, analyze data, and help in the development or characterization of therapeutic antibodies. These positions are commonly found in pharmaceutical companies, biotechnology firms, and research institutions. Candidates typically have a background in biochemistry, molecular biology, or a related field, and experience with SPR instrumentation is highly valued.

What are the key skills and qualifications needed to thrive as an antibody spr?

To thrive as an Antibody Specialist, you need a solid background in biochemistry, molecular biology, and immunology, typically with at least a bachelor's or master's degree in a related field. Familiarity with laboratory techniques such as ELISA, Western blotting, and flow cytometry, as well as experience using lab management software, is crucial. Strong analytical thinking, attention to detail, and effective communication skills set top performers apart in this role. These competencies are essential to ensure precise experimental results, successful collaboration, and advances in antibody research and development.

What are the typical challenges faced in an antibody spr role when working on new therapeutic projects?

As an Antibody Specialist, you may encounter challenges such as optimizing antibody specificity and affinity, troubleshooting unexpected results in assays, and collaborating with cross-functional teams like molecular biology and bioinformatics. Balancing project timelines with rigorous validation processes requires strong organizational skills. Success in this role often depends on proactive communication with team members and staying updated with the latest advancements in antibody engineering and therapeutic development.

What is the difference between Antibody Spr vs Immunoassay Technician?

AspectAntibody SprImmunoassay Technician
Required CredentialsBachelor's in biology, biochemistry, or related field; laboratory experienceSimilar; often requires a bachelor's degree and lab skills
Work EnvironmentResearch labs, biotech companies, pharmaceutical firmsClinical labs, research institutions, healthcare settings
Industry UsageBiotech, pharmaceutical, researchHealthcare, diagnostics, research
Common Search/ComparisonAntibody Spr vs Immunoassay Technician

Both roles involve laboratory work related to immunology and diagnostics. Antibody Spr typically focuses on developing and testing antibody-based products, while Immunoassay Technicians perform tests to detect specific substances in samples. While their credentials and work environments overlap, their specific responsibilities differ, making them distinct but related careers in the biotech and healthcare industries.

Infographic showing various Antibody Spr job openings in the United States as of September 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution.

Sr Scientist, Antibody Discovery

Quincy, MA • On-site

Twist Bioscience
Biotechnology Research and Development • 1 - 5K employees

$96K - $131K/yr

Full-time

Re-posted yesterday


Twist Bioscience rating

7.7

Company rating: 7.7 out of 10

Based on 7 frontline employees who took The Breakroom Quiz


Job description

Sr Scientist, Antibody Discovery (onsite in Quincy, MA)
Job Description
This is an individual contributor role that provides support for bioanalytical characterization for a variety of assays critical for characterizing therapeutic antibody candidates. This role will work closely with our Antibody Characterization and Protein Analytics team at our Quincy, MA location and is responsible for analyzing, optimizing, and troubleshooting a range of workflows, including SPR and BLI affinity analysis, developability assays, flow cytometry, functional assays, and target binding characterization.
What You'll Be Doing:
  • As an individual contributor Senior Scientist, you will support members of multiple scientific teams as a Project Lead, but will not directly manage team members.
  • Guide multiple projects per day to ensure scientific excellence and execution for antibody projects involving binding affinity determination (SPR, BLI) and developability assays (i.e. aSEC, CIC, HIC, BVP-ELISA, AC-SINS, plate-based off-target assays, DLS, and nanoDSF) for a variety of antibody and biologics formats (IgG, VHH, Minibinders, etc.)
  • Assist cross-functionally with the wet lab teams, Project Management team and scientific leaders across multiple sites within the company to ensure exquisite execution of individual projects, while also providing guidance for future assay integration and improvement in the antibody discovery workflow.
  • Provide technical guidance (assay development, analysis, and data reporting) for antibody-based projects in a range of areas, including high-throughput ELISA, flow cytometry, kinetic assays (BLI and SPR), developability assays, advanced/custom characterization, and functional screening.
  • Serve as an end-to-end technical lead for a variety of in vivo antibody discovery programs and contract services, contributing to scientific planning and feasibility review during project scoping.
  • Review, critically analyze, and present data to customers for a variety of concurrent antibody discovery programs.
  • Work closely with the Project Management team to communicate timelines and deliverables to internal and external stakeholders and customers.
  • Spend time performing wet-lab benchwork alongside the team based on workflow and assay development needs. It is anticipated that the role would involve an 80/20 split of analysis vs wet lab time.
What You'll Bring:
  • Strong knowledge of antibody and biologics characterization is required.
  • Previous experience with Carterra SPR systems, Octet BLI, and/or developability assays (HPLC and high throughput plate-based) is required. Further direct experience is expected with ELISA, SDS-PAGE, protein quantification, and endotoxin assays.
  • Experience in high-throughput assays (1,000s of samples) is preferred.
  • Ability to troubleshoot scientific processes, make sound scientific decisions on tight timelines, and accurately analyze and report data with utmost attention to detail.
  • Ability to work simultaneously on multiple workflows, prioritizing effectively.
  • Effectively communicate project updates, risks, and progress to the manager and cross-functional team members in a timely and professional manner.
  • Actively participate in team meetings, clearly articulating needs, concerns, and proposed solutions to drive efficient collaboration.
Requirements
  • PhD in a related technical field with 5+ years of experience in biopharmaceutical analytical development or master's in a. related technical field with 10+ years of experience
  • Expert knowledge of antibody biologics characterization assays: extensive hands-on experience required in Carterra SPR, Octet BLI, ELISA, flow cytometry, and antibody developability characterization.
  • Advanced understanding of in vivo antibody discovery concepts.
  • Strong track record of developing, executing, and analyzing common assay formats for antibody discovery, such as high-throughput screening, epitope binning, ligand blocking analysis, affinity analysis, and cell-based functional assays.
  • Demonstrated capability to work autonomously, prioritizing responsibilities within a high-pressure setting characterized by concurrent projects and time-critical workflows.
  • Proven ability to assess, interpret, and present complex scientific data effectively and with a high level of integrity and ethics.
  • Exceptional written and verbal communication skills, including external customer-facing communication.
  • Highly organized and detail-oriented with a focused, problem-solving mentality to address projects and logistics.

About Twist Bioscience
Twist Bioscience synthesizes genes from scratch, known as "writing" DNA. Just as children learn to both read and write, the next phase of development for the genomics revolution is the ability to write DNA.
At Twist Bioscience, we work in service of people who are changing the world for the better. In fields such as health care, agriculture, industrial chemicals and data storage, our unique silicon-based DNA Synthesis Platform provides precision at a scale that is otherwise unavailable to our customers.
Twist Bioscience Corporation is an Equal Opportunity Employer. Twist Bioscience Corporation provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law.
The base cash compensation for this Massachusetts-based role is below. In addition to base salary, this role is eligible for bonus, equity, and a generous benefits package. Final compensation amounts are determined by multiple factors, including candidate skill, experience, expertise, and location and may vary from the amount listed above. Compensation may be different in other locations.
Massachusetts Pay Range
$131,000-$142,600 USD

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