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Ai Software Developer Jobs in Minnesota (NOW HIRING)

Senior Software Developer C#

Oslo, MN

$55.50 - $73.50/hr

Quality and AI-Assisted Engineering * Hold a high bar for code quality -- automated testing, code ... Master's degree in Computer Science, Software Engineering, or a closely related STEM discipline.

Lead Software Engineer, AI Are you passionate about building AI-driven software that transforms how professionals work? Join our fast-moving, forward-thinking group that is creating AI-driven ...

Lead Software Engineer, AI Are you passionate about building AI-driven software that transforms how professionals work? Join our fast-moving, forward-thinking group that is creating AI-driven ...

Agentic AI Developer

Minneapolis, MN · On-site

$80K - $158K/yr

Software Engineer - AI Agents (Azure AI Foundry) Role Overview We are seeking a Software Engineer specializing in Agentic AI to design, build, and deploy intelligent AI agents leveraging Azure AI ...

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Ai Software Developer information

See Minnesota salary details

$47K

$109.5K

$162.6K

How much do ai software developer jobs pay per year?

As of Jul 16, 2026, the average yearly pay for ai software developer in Minnesota is $109,542.00, according to ZipRecruiter salary data. Most workers in this role earn between $88,100.00 and $127,300.00 per year, depending on experience, location, and employer.

How much do AI software developers make?

AI software developers typically earn between $80,000 and $150,000 annually, depending on experience, location, and industry. Senior roles or those with specialized skills in machine learning and deep learning can earn higher salaries, often exceeding $200,000.

What are the key skills and qualifications needed to thrive in the Ai Software Developer position, and why are they important?

To thrive as an AI Software Developer, you need strong programming skills in languages such as Python or Java, a background in computer science or a related field, and a solid understanding of machine learning algorithms. Familiarity with frameworks like TensorFlow, PyTorch, and experience with data processing tools or cloud platforms is highly valued, while certifications in AI or machine learning can be advantageous. Creative problem-solving, collaboration, and effective communication are key soft skills that help you integrate complex solutions and work effectively within multidisciplinary teams. These competencies are crucial for developing, deploying, and maintaining innovative AI systems that deliver real-world value.

What is a $900000 AI job?

A $900,000 AI job typically refers to a high-level position in artificial intelligence, such as senior AI software developer, machine learning engineer, or AI research scientist, often requiring advanced skills, experience, and sometimes leadership responsibilities. Such roles may involve developing complex algorithms, managing large datasets, and utilizing tools like Python, TensorFlow, or PyTorch, with compensation reflecting expertise and impact in the field.

What is an AI Software Developer job?

An AI Software Developer designs, develops, and implements artificial intelligence solutions, such as machine learning models, neural networks, and automation tools. They work with algorithms, big data, and programming languages like Python to build intelligent applications. Their responsibilities include data preprocessing, model training, testing, and deploying AI systems for various industries.

What engineer makes 500,000 a year?

Senior AI software engineers or machine learning engineers with extensive experience, advanced skills in deep learning, and expertise in frameworks like TensorFlow or PyTorch can earn salaries approaching or exceeding $500,000 annually, especially in high-cost-of-living areas or within top tech companies. Compensation often includes base salary, bonuses, and stock options, reflecting their specialized knowledge and impact on product development.

Can AI do the job of a software developer?

AI software developers create and improve AI systems, but AI currently cannot fully replace human software developers who design, code, test, and maintain complex software applications. AI tools can assist with coding, debugging, and automation, but human expertise remains essential for problem-solving, creativity, and understanding user needs.

What are some common challenges faced by AI Software Developers in day-to-day work?

AI Software Developers often encounter challenges such as ensuring data quality and quantity, tuning complex models for optimal performance, and integrating AI components seamlessly into existing software systems. Balancing the need for accuracy with computational efficiency while addressing issues of scalability and maintainability can also be demanding. Additionally, they must continuously stay updated with rapidly evolving AI technologies and best practices. Overcoming these challenges requires adaptability, a passion for continuous learning, and close collaboration with data scientists, product managers, and other engineers.

What cities in Minnesota are hiring for Ai Software Developer jobs? Cities in Minnesota with the most Ai Software Developer job openings:
Infographic showing various Ai Software Developer job openings in Minnesota as of July 2026, with employment types broken down into 74% Full Time, 23% Part Time, and 3% Contract. Highlights an 66% Physical, 3% Hybrid, and 31% Remote job distribution, with an average salary of $109,542 per year, or $52.7 per hour.
Principal AI/ML Engineer - AI Program

Principal AI/ML Engineer - AI Program

Mayo Clinic

Rochester, MN • On-site

Full-time

Medical, Dental, Vision, Retirement

Posted 21 days ago


Mayo Clinic rating

7.9

Company rating: 7.9 out of 10

Based on 689 frontline employees who took The Breakroom Quiz

105th of 886 rated healthcare providers


Job description

AI/ML Engineers at Mayo Clinic play a pivotal role in the union of data, systems, and computer sciences. They work closely with a multidisciplinary team, including clinicians, user experience designers, product managers, IT professionals, and external partners, to develop and deploy effective, efficient, and ethical AI/ML solutions into clinical practice to enhance patient care and operational efficiency.
As a Principal AI/ML Engineer, you will lead the full spectrum of the AI life cycle from ideation to production. You understand the clinical environment well, including workflows, challenges, and requirements of healthcare providers and patients. You will leverage advanced techniques in AI/ML to analyze vast amounts of healthcare data, including patient records, medical imaging, and genomic information, to develop AI solutions that meet clinical needs and are integrated smoothly into clinical processes. This includes guiding the design and evaluation of foundation models, vision encoders, multimodal architectures, representation learning approaches, and data fusion strategies that enable robust clinical AI applications.  You will develop, integrate, and standardize software components and create, maintain, and follow quality system procedures. You will guide the engineering of systems that are pivotal to developing and deploying these solutions, which encompass everything from design requirements, development, component creation, verification, non-clinical validation, and risk mitigation to ensure our digital health technology products meet and exceed regulatory requirements and setting new benchmarks for safety and effectiveness in clinical settings. Your expertise will also extend to facilitating consistent and automated AI software solution development and releases through the design, testing, and maintenance of tools and associated CI/CD pipelines.

This role is instrumental in leading consultative services to departments and divisions, offering insights into complex business problems. The role requires deep technical judgment in understanding how AI models learn, represent information, and perform across diverse clinical modalities, enabling informed decisions regarding model design, explainability, reliability, and clinical suitability. Your ability to communicate complex findings in easily understandable terms to non-technical users will bridge the gap between sophisticated AI technologies and clinical applications.
  Providing strategic direction and technical leadership for AI Engineering initiatives.
  Working with leadership team to define the AI roadmap and prioritize projects aligned with organizational objectives.
  Leading component design, development, integration, and standardization to create AI-driven solutions that seamlessly integrate into clinical practice to enhance patient care and clinic operations.
  Leading the collaboration with multidisciplinary teams, including clinicians, user experience designers, product managers, and IT professionals, to understand user needs, workflows, and clinical requirements and assess feasibility. Translating user feedback and requirements into design concepts and usability specifications for AI solutions.
  Leading the interpretation of data analysis to guide strategic choices and clarify complex insights for non-technical users to connect AI technologies and clinical applications. 
  Leading consultative services to clinical work units or AI product teams, offering insights and strategies to address complex business problems.
  Leveraging machine learning techniques such as deep learning, natural language processing, computer vision, large language models, etc., to lead the design, development, and deployment of end-to-end AI solutions for healthcare applications. This includes evaluating and guiding architectural choices involving vision encoders, multimodal fusion approaches, representation learning, and model adaptation strategies.
  Establish rigorous evaluation methodologies and performance metrics to assess the effectiveness, usability, and impact of AI solutions in real-world healthcare settings.
  Ensuring compliance with ethical guidelines, regulatory requirements, and data privacy standards in the development and deployment of AI solutions by the AI development team.
  Overseeing the engineering of systems crucial for developing and deploying AI solutions.
  Facilitating consistent and automated AI software solution development and releases through the design, testing, and maintenance of tools and associated CI/CD pipelines.
  Defining and implementing best practices and standards for AI development and deployment methodologies, tools, and platforms.
  Providing mentorship, guidance, and technical leadership to junior engineers within the AI enablement team. May have supervisory responsibilities.
  Fostering a culture of collaboration, innovation, and knowledge sharing across the organization.
  Supporting talent development initiatives, including training programs, technical workshops, and skill-building activities to enhance team capabilities.
  Contributing to the development of new AI methods and technologies that can advance the state-of-the-art in healthcare AI, including novel approaches in multimodal learning, foundation models, representation learning, computer vision, and clinical AI evaluation. 
  Publishing and presenting the results of AI development and translation in peer-reviewed journals and conferences.
This is a full-time remote position within the United States.  
Mayo Clinic will not sponsor or transfer visas for this position including F1 OPT STEM.
 

Why Mayo Clinic

Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans - to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.

Benefits Highlights
  • Medical: Multiple plan options.
  • Dental: Delta Dental or reimbursement account for flexible coverage.
  • Vision: Affordable plan with national network.
  • Pre-Tax Savings: HSA and FSAs for eligible expenses.
  • Retirement: Competitive retirement package to secure your future.
Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is. 

Equal Opportunity

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law".  Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.

Required Qualifications:
A master's degree in engineering, computer science, mathematics, health science, or a related field with 7 years of relevant experience, or a bachelor's degree with 9 years of relevant experience. 
  Extensive (7+ years) experience applying AI and machine learning in production healthcare environments or similar highly regulated or technology focused industries, showcasing an acute understanding of healthcare technology.
  Demonstrated leadership in managing complex projects, with a proven ability to navigate intricate project requirements and deliver successful outcomes.
  Proven success in fostering collaboration across diverse teams and effectively communicating complex technical concepts to non-technical stakeholders.
  Demonstrated expertise in cloud infrastructure environment and software development tools.
  Experience working with large, complex, and heterogeneous data sets, preferably in healthcare. 
  Strong skills in AI/ML techniques and frameworks.
  Expertise with best practices in data engineering, data science, AI Engineering, and the MLOps communities.
  In-depth knowledge of healthcare domain, including clinical workflows, electronic health records, medical terminologies, regulatory requirements, and industry standards.
  Demonstrated leadership in administration, education, software development, and technical reporting. 
  Experience mentoring and training less-experienced team members, coupled with strong interpersonal, communication, and time management skills.


Preferred Qualifications:
A Ph.D. or other doctorate is preferred. 
  Strong expertise in AI/ML techniques and frameworks, such as deep learning, natural language processing, computer vision, multimodal AI, representation learning, and Generative AI, with proficiency in tools like Python, TensorFlow, PyTorch, sci-kit-learn, Keras, etc.
  Experience with healthcare industry informatics standards, best practices, and common data models. Participation in national or international standards organizations or other domain-specific professional organizations, or extensive implementation experience with common data, development, and deployment standards.
  Excellent communication, collaboration, and stakeholder management skills, with the ability to effectively engage with diverse stakeholders and translate complex technical concepts and results to non-technical audiences.
  Demonstrated experience leading technical/quantitative teams in a regulated environment.
  Familiarity with systems or quality engineering best practices, regulatory standards, and compliance frameworks, with the ability to adapt these effectively to different project scenarios.
  Demonstrated experience creating risk management files and verification/validation strategies for digital health technology products within the healthcare industry.
  Demonstrated expertise in user-centered design, human factors engineering, usability testing methodologies, and evaluation across AI product development. Ability to lead expert reviews using established usability practices and methods. Presents findings in easy-to-understand terms for the business or clinical practice.
  Strong problem-solving abilities, critical thinking skills, and a passion for driving innovation and positive change in healthcare through AI technology.


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About Mayo Clinic

Sourced by ZipRecruiter

Mayo Clinic is the largest integrated, not-for-profit medical group practice in the world. We're building the future, one where the best possible care is available to everyone — and more people can heal at home. Our relentless research turns into earlier diagnoses and new cures. That's how we inspire hope in those who need it most. At Mayo Clinic, experts work together to solve the most challenging unmet needs of patients. Our history of innovation dates back almost 150 years, when brothers Will and Charlie Mayo pioneered an integrated, team-based approach to medicine. Today, that trailblazing spirit drives innovations like Mayo Clinic Platform — which powers new technologies to change how care is delivered to all.

Industry

Hospitals

Company size

10,000+ Employees

Headquarters location

Rochester, MN, US

Year founded

1919