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3D Cell Culture Jobs (NOW HIRING)

Tufts University

Research Technician

Medford, MA · On-site

$24.90 - $28.90/hr

... some cell culture (tissue isolation, passaging, freezing both of 2D/3D cultures), bioassays, and analysis in collaboration with lab members. RESPONSIBILITITES AND ROLES: The Gnecco Lab Research ...

Tufts University

Research Technician

Medford, MA · On-site

$20.90 - $28.90/hr

... some cell culture (tissue isolation, passaging, freezing both of 2D/3D cultures), bioassays, and analysis in collaboration with lab members. RESPONSIBILITITES AND ROLES: The Gnecco Lab Research ...

Corning

Marketing Communications Manager

Tewksbury, MA · On-site

In this role, you will work with internal business clients to develop integrated marketing communications strategies and tactics to support 3D Cell Culture and Drug Discovery new and existing ...

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How much do 3d cell culture jobs pay per hour?

As of Aug 16, 2026, the average hourly pay for 3d cell culture in the United States is $21.64, according to ZipRecruiter salary data. Most workers in this role earn between $16.83 and $27.16 per hour, depending on experience, location, and employer.

What is 3D cell culture?

3D cell culture is a technique where cells are grown in a three-dimensional environment, which better mimics the natural conditions found in living tissues compared to traditional two-dimensional (2D) cell cultures. This method allows cells to interact with their surroundings in all directions, leading to more physiologically relevant behaviors and responses. 3D cell culture is widely used in research for drug development, cancer studies, and tissue engineering because it provides more accurate models for studying cell function, disease, and treatment effects.

What are the common challenges faced when transitioning from traditional 2D to 3D cell culture techniques in the lab?

One of the most common challenges in moving from 2D to 3D cell culture is mastering the new protocols and equipment required for 3D systems, such as spheroid or organoid cultures. It often takes time to optimize cell seeding densities, matrix compositions, and nutrient delivery to ensure reproducible results. Additionally, analyzing and imaging 3D cultures can be more complex, requiring familiarity with advanced microscopy and data analysis tools. Collaborating closely with team members in bioengineering or imaging is also important to troubleshoot and develop robust workflows.

What is the difference between 3D Cell Culture vs Laboratory Technician?

Aspect3D Cell CultureLaboratory Technician
Required CredentialsTypically requires a degree in biology, biotechnology, or related fieldsUsually requires a high school diploma or associate degree, with some roles needing a bachelor's
Work EnvironmentResearch labs focusing on cell biology, tissue engineering, and regenerative medicineVarious labs including clinical, research, and industrial settings
Industry UsagePrimarily in biotech, pharmaceutical, and academic researchWidely used across healthcare, research, and manufacturing sectors

3D Cell Culture specialists focus on developing and maintaining three-dimensional cell models for research, while Laboratory Technicians support a broad range of lab operations. Both roles require laboratory skills, but 3D Cell Culture positions are more specialized in cell biology and tissue engineering.

What are the key skills and qualifications needed to thrive as a 3D cell culture specialist, and why are they important?

To excel as a 3D Cell Culture Specialist, you need a solid background in cell biology, tissue engineering, and hands-on laboratory experience, typically supported by a degree in life sciences or biomedical engineering. Familiarity with specialized tools such as bioreactors, 3D printers, and imaging systems, as well as knowledge of protocols for culturing and analyzing 3D cell models, is essential. Attention to detail, problem-solving skills, and effective communication are crucial for troubleshooting experiments and collaborating with multidisciplinary teams. These skills are vital to ensure the reproducibility and reliability of complex biological experiments in cutting-edge research and drug development.
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3D Cell Culture jobs near you
Infographic showing various 3D Cell Culture job openings in the United States as of August 2026, with employment types broken down into 1% As Needed, 82% Full Time, 15% Part Time, and 2% Contract. Highlights an 92% Physical, 2% Hybrid, and 6% Remote job distribution, with an average salary of $45,021 per year, or $21.6 per hour.

Senior Scientist, Cell Therapy Islet

Sana Biotechnology

Cambridge, MA

$160K - $190K/yr

Full-time

Re-posted 6 days ago

Job description

About the role  

Sana Biotechnology is growing, and we are hiring new team members who believe in the potential of engineered cells as medicines, who want to challenge the status quo, and who lead with the desire to work on novel ideas. You will join the Beta Islet Team at the Cambridge location to optimize 3D expansion and differentiation in stem cell (SC)-islet differentiation. As a Senior Scientist, you will execute optimization experiments critical to scaling up our differentiation process. The ideal candidate should have ample experience handling bioreactors and performing directed PSC differentiation in 3D. The ability to work in a highly collaborative environment and learn from each other will be essential to your success.

What you'll do

  • Execute routine 2D and 3D PSC expansion, passaging and directed SC-islet differentiation
  • Design optimization experiments with the goal to achieve a highly scalable and robust 3D SC-islet differentiation process that is compliant to manufacturing standards
  • Optimize the differentiation protocol to achieve highly pure on-target populations
  • Hands-on experience with closed systems (tube welder, sealer, single-use assemblies)
  • Expertise in controlled bioreactor setup, operation, automation, and process control (DO, pH, perfusion, agitation)
  • Collaborate and communicate findings with other team members
  • Maintain excellent scientific documentation and contribute to SOP development
  • Assure compliance with all relevant lab safety and biosafety regulations
  • Demonstrate Sana's core values and the attributes that support these core values (Lead from every seat, Thrive as a team, Make it happen)
  • Engage in crucial conversations by providing and receiving feedback supporting the growth and development of team member
  • Demonstrate ability to engage and effectively influence team members across multidisciplinary teams while prioritizing multiple projects and meeting deadlines
  • Drive curiosity, scientific rigor, and excellent problem-solving skills across a fast-paced performance-driven environment
  • Innate ability to assess talent that will help grow the organization and add to Sana's culture

What we're looking for

  • PhD in Stem cell biology, biochemical/biomedical Engineering or related fields with 3-5 years of direct cell therapy industry experience
  • Significantly experienced and knowledgeable in operating various types of bioreactors for suspension culture.
  • Experienced with bioreactor control software, process development tools, or DOE-base optimization is preferred
  • Significantly experienced in operating a closed system for cell culture
  • Significantly experienced in Flow cytometry, Immunofluorescent staining,
  • Proficient with standard flow cytometry and imaging software (e.g. FACSDiva, FlowJo, ImageJ, Halo, etc.) 

What will separate you from the crowd   

  • Knowledge or direct experience in directed stem cell differentiation toward pancreatic islet lineage
  • Proven ability to optimize differentiation yield and reproducibility across platforms
  • Passion for GMP transition, automation, and continuous process improvement
  • Strong cross-functional collaboration skills and enthusiasm for advancing cell therapies to the clinic
  • Significant experience in operating large bioreactors (15L+) for cell therapy purposes
  • Expertise in controlled bioreactor setup, operation, automation, and process control (DO, pH, perfusion, agitation)
  • Proven ability to optimize differentiation yield and reproducibility across platforms

What you should know

  • The base pay range for this position at commencement of employment is expected to be between $160,000 and $190,000/year; however, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience

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