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3D Cell Culture Jobs (NOW HIRING)

Orion Group

Biologist III

Worcester, MA · On-site

$48 - $52/hr

The ideal candidate brings hands-on expertise in primary cell culture, 3D cell models, immunoassays, and molecular biology techniques, and thrives both independently and within a collaborative team ...

Columbia University

Research Assistant

New York, NY · On-site

$58K - $62K/yr

Prepare 3D cell culture constructs, including hydrogel encapsulation systems; assess cell viability and functional metrics post-fabrication. Perform primary cell isolation from human and animal ...

Frontage Laboratories

Associate Scientist

Exton, PA · On-site

Experience with Organoids and 3D cell culture is a plus, but not required. * Experience with molecular biology techniques (qPCR/ddPCR/ Elisa/ Western Blot) is a plus, but not required. * Hands-on ...

FUJIFILM Biotechnologies

$92K - $126K/yr

Familiarity with advanced culture systems such as 3D cell culture, organ-on-a-chip platforms, or complex co-culture models is preferred.Demonstrated ability to independently conduct experiments ...

Fujifilm

Senior Scientist - Applications

Madison, WI

$92K - $126K/yr

Stem cell culture experience or experience with our differentiated cell product line is strongly preferred. * Familiarity with advanced culture systems such as 3D cell culture, organ-on-a-chip ...

Fujifilm

Senior Scientist - Applications

Madison, WI · On-site

$92K - $126K/yr

Stem cell culture experience or experience with our differentiated cell product line is strongly preferred. * Familiarity with advanced culture systems such as 3D cell culture, organ-on-a-chip ...

Fujifilm

Senior Scientist - Applications

Madison, WI · On-site

$92K - $126K/yr

Stem cell culture experience or experience with our differentiated cell product line is strongly preferred. * Familiarity with advanced culture systems such as 3D cell culture, organ-on-a-chip ...

Vivodyne

Associate Scientist

San Francisco, CA · On-site

Support routine expansion, maintenance, and characterization of primary human cell cultures using aseptic technique. * Assist with 3D tissue seeding, maintenance, feeding, harvesting, and downstream ...

Jj

Postdoctoral Scholar, Translational PK/PD

Spring House, PA · Hybrid

$46K - $63K/yr

Building predictive in vitro models using 2D/3D cell culture systems and cell-based assays to characterize ADC and payload activity. * Using experimental data, PK/PD modeling, and quantitative ...

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3D Cell Culture information

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How much do 3d cell culture jobs pay per hour?

As of Jul 26, 2026, the average hourly pay for 3d cell culture in the United States is $21.64, according to ZipRecruiter salary data. Most workers in this role earn between $16.83 and $27.16 per hour, depending on experience, location, and employer.

What is 3D cell culture?

3D cell culture is a technique where cells are grown in a three-dimensional environment, which better mimics the natural conditions found in living tissues compared to traditional two-dimensional (2D) cell cultures. This method allows cells to interact with their surroundings in all directions, leading to more physiologically relevant behaviors and responses. 3D cell culture is widely used in research for drug development, cancer studies, and tissue engineering because it provides more accurate models for studying cell function, disease, and treatment effects.

What are the common challenges faced when transitioning from traditional 2D to 3D cell culture techniques in the lab?

One of the most common challenges in moving from 2D to 3D cell culture is mastering the new protocols and equipment required for 3D systems, such as spheroid or organoid cultures. It often takes time to optimize cell seeding densities, matrix compositions, and nutrient delivery to ensure reproducible results. Additionally, analyzing and imaging 3D cultures can be more complex, requiring familiarity with advanced microscopy and data analysis tools. Collaborating closely with team members in bioengineering or imaging is also important to troubleshoot and develop robust workflows.

What is the difference between 3D Cell Culture vs Laboratory Technician?

Aspect3D Cell CultureLaboratory Technician
Required CredentialsTypically requires a degree in biology, biotechnology, or related fieldsUsually requires a high school diploma or associate degree, with some roles needing a bachelor's
Work EnvironmentResearch labs focusing on cell biology, tissue engineering, and regenerative medicineVarious labs including clinical, research, and industrial settings
Industry UsagePrimarily in biotech, pharmaceutical, and academic researchWidely used across healthcare, research, and manufacturing sectors

3D Cell Culture specialists focus on developing and maintaining three-dimensional cell models for research, while Laboratory Technicians support a broad range of lab operations. Both roles require laboratory skills, but 3D Cell Culture positions are more specialized in cell biology and tissue engineering.

What are the key skills and qualifications needed to thrive as a 3D Cell Culture Specialist, and why are they important?

To excel as a 3D Cell Culture Specialist, you need a solid background in cell biology, tissue engineering, and hands-on laboratory experience, typically supported by a degree in life sciences or biomedical engineering. Familiarity with specialized tools such as bioreactors, 3D printers, and imaging systems, as well as knowledge of protocols for culturing and analyzing 3D cell models, is essential. Attention to detail, problem-solving skills, and effective communication are crucial for troubleshooting experiments and collaborating with multidisciplinary teams. These skills are vital to ensure the reproducibility and reliability of complex biological experiments in cutting-edge research and drug development.
More about 3D Cell Culture jobs
What cities are hiring for 3D Cell Culture jobs? Cities with the most 3D Cell Culture job openings:
What states have the most 3D Cell Culture jobs? States with the most job openings for 3D Cell Culture jobs include:
What job categories do people searching 3D Cell Culture jobs look for? The top searched job categories for 3D Cell Culture jobs are:
3D Cell Culture jobs near you
Infographic showing various 3D Cell Culture job openings in the United States as of July 2026, with employment types broken down into 88% Full Time, 9% Part Time, and 3% Contract. Highlights an 88% Physical, 4% Hybrid, and 8% Remote job distribution, with an average salary of $45,021 per year, or $21.6 per hour.
Biologist III

Biologist III

Orion Group

Worcester, MA • On-site

$48 - $52/hr

Contractor

Posted 13 days ago

Job description

Biologist III
$48 - $52/hr with medical benefits available at a cost
6 month initial contract with possibility of extensions
100% onsite in Worcester, MA
Monday - Friday 8 am to 5 pm
Orion Project Services and our largest US client are excited to bring you an amazing contract opportunity for a Biologist III. This position offers a unique opportunity to work at the interface of basic research and early drug discovery in a fast-paced, multidisciplinary environment. The ideal candidate brings hands-on expertise in primary cell culture, 3D cell models, immunoassays, and molecular biology techniques, and thrives both independently and within a collaborative team setting.
Job Description:
We are seeking a highly motivated and skilled scientist to join our Immunology Discovery team in Worcester, MA. In this role, you will collaborate with multiple cross-functional teams to advance portfolio projects, with a core focus on human intestinal organoid biology, ex vivo tissue processing, and cell-based in vitro assay execution. Responsibilities span the full experimental cycle from assay design and execution to data analysis and cross-team communication across diverse and technically demanding cell systems.
Key Responsibilities:
  • Culture, passage, and plate human intestinal organoids to support the group's research objectives.
  • Perform assays in primary 3D cell culture models such as Transwells or MPS/CIVM platforms.
  • Test biologic and small molecule compounds in cell-based assays for functional readouts, including cell proliferation, cytokine release, and gene expression.
  • Execute advanced molecular and cellular biology techniques, including but not limited to flow cytometry (FACS), ELISA, MSD, and qPCR.
  • Process human tissue ex vivo and isolate organoids, fibroblasts, and immune cells from human tissue or blood.
  • Work independently on the design, execution, and interpretation of experimental results to validate project-relevant hypotheses.
  • Maintain close communication with multiple teams to support human intestinal organoid cell needs.
  • Implement and innovate new experimental protocols and techniques as needed.
  • Analyze, interpret, document, and report data consistently, concisely, and rigorously, both to individual stakeholders and in group settings.
  • Demonstrate scientific excellence through dedicated contributions to multiple projects in a fast-paced, multidisciplinary environment.
  • Drive project impact primarily through hands-on, lab-based activities.
Qualifications and Requirements:
Required skills:
  • At least a Bachelor's degree in Biological Sciences or a related field, with 4+ years of experience in an industry setting.
  • In vitro cell culture experience, including sterile techniques and handling of challenging cell types.
  • Experience working with primary human organoids.
  • Comfortable handling with ex vivo human tissue and processing.
  • Experience with 3D cell culture models such as transwells or MPS/CIVM platforms.
  • Proficiency in ELISA, MSD or Luminex
  • Ability to learn new skills and apply them in a fast-paced research environment.
  • Excellent oral and written communication skills with a collaborative mindset.
  • Comfortable managing, shifting timelines and evolving work priorities.
  • Ability to work both independently and as part of a team.
  • Strong creativity, problem-solving skills, and attention to detail
Skills that are nice to have:
  • Experience with cell-based assay development.
  • Proficiency in multi-color flow cytometry.
  • Experience with gene expression analysis by qPCR.
  • Experience working with fibroblasts and immune cells, including T cells, B cells, and monocytes.

People are our business worldwide
Orion Group was founded in 1987 and is now one of the largest, independent, international recruitment companies. We have a network of 200 employees working from 24 offices, delivering a range of services - Talent Acquisition, Recruitment Outsourcing Services, Retained Search, Global Workforce Solutions, Completions & Commissioning and Materials Management - across 68 countries. As a global leader in workforce solutions, we recruit personnel across the Engineering & Technical, Office & Commercial, Scientific and Skilled Trades disciplines, for sectors including Oil & Gas, Life Science, Power & Utilities, Constructions & Infrastructure, Manufacturing and Renewables.

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