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3D Cell Culture Jobs (NOW HIRING)

Frontage Laboratories

Associate Scientist

Exton, PA · On-site

Experience with Organoids and 3D cell culture is a plus, but not required. * Experience with molecular biology techniques (qPCR/ddPCR/ Elisa/ Western Blot) is a plus, but not required. * Hands-on ...

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How much do 3d cell culture jobs pay per hour?

As of Aug 27, 2026, the average hourly pay for 3d cell culture in the United States is $21.64, according to ZipRecruiter salary data. Most workers in this role earn between $16.83 and $27.16 per hour, depending on experience, location, and employer.

What is 3D cell culture?

3D cell culture is a technique where cells are grown in a three-dimensional environment, which better mimics the natural conditions found in living tissues compared to traditional two-dimensional (2D) cell cultures. This method allows cells to interact with their surroundings in all directions, leading to more physiologically relevant behaviors and responses. 3D cell culture is widely used in research for drug development, cancer studies, and tissue engineering because it provides more accurate models for studying cell function, disease, and treatment effects.

What are the common challenges faced when transitioning from traditional 2D to 3D cell culture techniques in the lab?

One of the most common challenges in moving from 2D to 3D cell culture is mastering the new protocols and equipment required for 3D systems, such as spheroid or organoid cultures. It often takes time to optimize cell seeding densities, matrix compositions, and nutrient delivery to ensure reproducible results. Additionally, analyzing and imaging 3D cultures can be more complex, requiring familiarity with advanced microscopy and data analysis tools. Collaborating closely with team members in bioengineering or imaging is also important to troubleshoot and develop robust workflows.

What are the key skills and qualifications needed to thrive as a 3D cell culture specialist, and why are they important?

To excel as a 3D Cell Culture Specialist, you need a solid background in cell biology, tissue engineering, and hands-on laboratory experience, typically supported by a degree in life sciences or biomedical engineering. Familiarity with specialized tools such as bioreactors, 3D printers, and imaging systems, as well as knowledge of protocols for culturing and analyzing 3D cell models, is essential. Attention to detail, problem-solving skills, and effective communication are crucial for troubleshooting experiments and collaborating with multidisciplinary teams. These skills are vital to ensure the reproducibility and reliability of complex biological experiments in cutting-edge research and drug development.

What is the difference between 3D Cell Culture vs Laboratory Technician?

Aspect3D Cell CultureLaboratory Technician
Required CredentialsTypically requires a degree in biology, biotechnology, or related fieldsUsually requires a high school diploma or associate degree, with some roles needing a bachelor's
Work EnvironmentResearch labs focusing on cell biology, tissue engineering, and regenerative medicineVarious labs including clinical, research, and industrial settings
Industry UsagePrimarily in biotech, pharmaceutical, and academic researchWidely used across healthcare, research, and manufacturing sectors

3D Cell Culture specialists focus on developing and maintaining three-dimensional cell models for research, while Laboratory Technicians support a broad range of lab operations. Both roles require laboratory skills, but 3D Cell Culture positions are more specialized in cell biology and tissue engineering.

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3D Cell Culture jobs near you
Infographic showing various 3D Cell Culture job openings in the United States as of August 2026, with employment types broken down into 1% As Needed, 82% Full Time, 15% Part Time, and 2% Contract. Highlights an 88% Physical, 2% Hybrid, and 10% Remote job distribution, with an average salary of $45,021 per year, or $21.6 per hour.

Cell Culture Facility Manager

The Fox Chase Cancer Center Foundation

Philadelphia, PA • On-site

Full-time

Posted 27 days ago

Job description

The manager of the Cell Culture Facility (CCF) coordinates delivery of outstanding mammalian cell culture services to laboratories at Fox Chase Cancer Center (FCCC). The manager will perform hands-on cell culture within the CCF workflow and assure CCF staff adheres to rigorous operating procedures to provide the highest quality reagents and technical services. The ideal candidate will have experience initiating and maintaining cultures of human and mouse primary cells in 2D and 3D, immortalizing primary cells, culturing and differentiating iPSCs, using a bioprinter, preparing B cell hybridoma fusions to generate monoclonal antibodies, preparing culture media and additives, and supporting liquid nitrogen banking. The manager will also be responsible for supervising and training CCF staff, interfacing with research investigators and their staff, coordinating purchases and service contracts, maintaining equipment, and organizing monthly staff meetings.
Education
Bachelor's Degree molecular biology, pathology, cell biology or related scientific discipline Required
Doctorate Degree molecular biology, pathology, cell biology or related scientific discipline Preferred
Master's Degree molecular biology, pathology, cell biology or related scientific discipline Preferred
Experience
3 years experience in management, including oversight of scientific staff Required
5 years experience and knowledge of mammalian cell biology research and cell culture
techniques Required
Licenses
 

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