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Remote Senior Full Stack Software Engineer Jobs in Columbus, OH

McKesson

AI Full stack Software Engineer

Columbus, OH · Remote

$110.30K - $183.80K/yr

We are seeking a highly skilled and motivated AI Full Stack Software Engineer to join our innovative team at CMM. In this role, you will be instrumental in designing, developing, and deploying end-to ...

McKesson

AI Full stack Software Engineer

Columbus, OH · Remote

$110.30K - $183.80K/yr

We are seeking a highly skilled and motivated AI Full Stack Software Engineer to join our innovative team at CMM. In this role, you will be instrumental in designing, developing, and deploying end-to ...

CoverMyMeds

AI Full stack Software Engineer

Columbus, OH · Remote

$110.30K - $183.80K/yr

We are seeking a highly skilled and motivated AI Full Stack Software Engineer to join our innovative team at CMM. In this role, you will be instrumental in designing, developing, and deploying end-to ...

MCKESSON

AI Full stack Software Engineer

Columbus, OH · Remote

$110.30K - $183.80K/yr

We are seeking a highly skilled and motivated AI Full Stack Software Engineer to join our innovative team at CMM. In this role, you will be instrumental in designing, developing, and deploying end-to ...

CipherStaff

.Net Full Stack Web Developer

Blacklick, OH · Remote

$8K - $120K/yr

Net Full Stack Developer. Remote job but applicants in Columbus, OH or Arlington, VA preferred ... Description Are you an established software engineer who enjoys automating tasks, solving hard ...

Staffingine LLC

Java Full Stack Developer

Columbus, OH · On-site

$50.75 - $65.50/hr

Java Full Stack Developer Job Location: Columbus, OH Job Type: Contract : * Java Full Stack ... Software Engineer should have general development skills, mainly in Java and JavaScript * General ...

Deloitte

Full Stack Engineer

Columbus, OH

As a Full-stack Software Engineer , you will actively engage in your engineering craft, taking a hands-on approach to multiple high-visibility projects. Your expertise will be pivotal in delivering ...

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Remote Senior Full Stack Software Engineer information

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$43K

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How much do remote senior full stack software engineer jobs pay per year?

As of May 28, 2026, the average yearly pay for remote senior full stack software engineer in Columbus, OH is $130,175.00, according to ZipRecruiter salary data. Most workers in this role earn between $107,200.00 and $152,600.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Remote Senior Full Stack Software Engineer, and why are they important?

To thrive as a Remote Senior Full Stack Software Engineer, you need advanced expertise in both front-end and back-end development, typically demonstrated by a degree in computer science or equivalent experience. Mastery of frameworks and tools such as React, Node.js, RESTful APIs, version control (Git), and familiarity with cloud platforms like AWS or Azure are commonly required, along with relevant certifications. Exceptional problem-solving, communication, and self-management skills are crucial for collaborating in distributed teams and delivering complex projects independently. These skills and qualities are vital for building robust applications, ensuring seamless teamwork, and driving successful project outcomes in a remote work environment.

How do Remote Senior Full Stack Software Engineers typically collaborate with distributed teams to ensure project success?

Remote Senior Full Stack Software Engineers frequently work with cross-functional teams spread across various locations and time zones. Effective collaboration relies on regular video meetings, agile project management tools, and clear documentation to keep everyone aligned. These engineers often take on a leadership role, mentoring junior developers and facilitating communication between frontend, backend, and product stakeholders. Proactively addressing challenges such as time zone differences and asynchronous communication is key to maintaining productivity and project momentum.

What does a Remote Senior Full Stack Software Engineer do?

A Remote Senior Full Stack Software Engineer is responsible for designing, developing, and maintaining both the front-end and back-end components of web applications, all while working from a remote location. They collaborate with other engineers, product managers, and designers to deliver scalable and efficient software solutions. Senior engineers typically lead technical decisions, mentor junior developers, and ensure best coding practices are followed. Their expertise spans multiple programming languages, frameworks, and tools used throughout the software development lifecycle.

What is the difference between Remote Senior Full Stack Software Engineer vs Remote Front End Developer?

AspectRemote Senior Full Stack Software EngineerRemote Front End Developer
Required SkillsProficiency in both front-end and back-end technologies, full project lifecycle experienceExpertise in front-end frameworks like React, Angular, or Vue, UI/UX design
Work EnvironmentCollaborates across backend and frontend teams, often involved in architecture decisionsFocuses primarily on UI development, design, and user experience
Common UsageUsed in roles requiring full project responsibility, backend integration, and system designUsed in roles emphasizing user interface, visual design, and client-side logic

The Remote Senior Full Stack Software Engineer and Remote Front End Developer roles share some skills but differ mainly in scope. The senior full stack engineer handles both front-end and back-end development, often leading entire projects, while the front end developer specializes in creating engaging user interfaces. Your choice depends on whether you prefer a broader technical role or a focus on UI/UX design.

What are the most commonly searched types of Senior Full Stack Software Engineer jobs in Columbus, OH? The most popular types of Senior Full Stack Software Engineer jobs in Columbus, OH are:
What are popular job titles related to Remote Senior Full Stack Software Engineer jobs in Columbus, OH? For Remote Senior Full Stack Software Engineer jobs in Columbus, OH, the most frequently searched job titles are:
What job categories do people searching Remote Senior Full Stack Software Engineer jobs in Columbus, OH look for? The top searched job categories for Remote Senior Full Stack Software Engineer jobs in Columbus, OH are:
What cities near Columbus, OH are hiring for Remote Senior Full Stack Software Engineer jobs? Cities near Columbus, OH with the most Remote Senior Full Stack Software Engineer job openings:
Remote Senior Full Stack Software Engineer jobs near you
Sr Associate AI Full stack Software Engineer

Sr Associate AI Full stack Software Engineer

McKesson

Columbus, OH • On-site, Remote

$86.60K - $144.40K/yr

Full-time

Posted 8 days ago

McKesson rating

7.8

Company rating: 7.8 out of 10

Based on 198 frontline employees who took The Breakroom Quiz

39th of 70 rated pharmaceutical

Job description

McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and services that make quality care more accessible and affordable. Here, we focus on the health, happiness, and well-being of you and those we serve - we care.

What you do at McKesson matters. We foster a culture where you can grow, make an impact, and are empowered to bring new ideas. Together, we thrive as we shape the future of health for patients, our communities, and our people. If you want to be part of tomorrow's health today, we want to hear from you.

We are seeking a highly skilled and experienced Sr. Associate AI Full stack Software Engineer to join our innovative team. This role will be responsible for designing, developing, and deploying end-to-end AI-powered software solutions, from front-end user interfaces to back-end services and AI model integration, within the healthcare domain.

Responsibilities

  • Develop and deliver AI-driven enterprise quality software applications.

  • Build scalable applications integrating Large Language Models and other AI tools (e.g. voice recognition, document parsing, image parsing, text to speech, RAG) into new and legacy codebases

  • Design and optimize data pipelines and datasets for AI system development and testing.

  • Communicate modern AI concepts (LLMs, vector databases etc.) to non-technical audiences

  • Iteratively craft effective prompts to maximize LLM performance and implement prompt caching strategies

  • Maintain prompt libraries & benchmark performance

  • Fine-tune & serve GPT-family, Llama

  • Develop AI agents Semantic Kernel

  • Prototype co-pilot experiences & autonomous workflows

  • Fully document all work at both the code level and application level.

  • The ability to learn and adapt in a changing environment.

  • Collaborate with other staff and outside stakeholders on large projects.

  • Must be passionate about creating solutions and solving complex problems.

Priority will be given to candidates who reside in the Columbus, OH metropolitan area.

We are unable to provide sponsorship for this role presently or in the future.

Minimum Qualifications

  • Minimum 2+ years of experience in Software development.

  • B.S. degree in Computer Science or related engineering discipline, or equivalent experience

Critical Skills

  • 2+ years of experience developing AI-powered applications using LLMs, voice, image, or speech models

  • Experience with AI evaluation metrics (precision, recall, F1, AUC) andMLOpsfor scalable deployment

  • Proven ability to build RAG solutions usingLangChain/LlamaIndexand vector databases

  • Strong experience with LLM optimization techniques (prompting, caching, cost awareness)

  • Proficiency in Python and AI/ML frameworks (OpenAI, TensorFlow,PyTorch)

  • Full-stack development experience, including Node.js (Express)

  • Experience with cloud platforms (AWS, GCP, or Azure)

  • Experience with modern DevOps tools (Git, Docker, Kubernetes)

  • Strong analytical/problem-solving skills to derive insights from data

Preferred Skills

  • Deep understanding of LLM model landscape (e.g., GPT variants, emerging models)

  • Experience with advanced LLM cost optimization techniques (batching, quantization)

  • Experience using AI coding assistants (GitHub Copilot, Cursor,Codeium/Windsurf)

  • Healthcare domain experience and ability to translate clinical/business needs into AI solutions

  • Strong cross-functional communication skills across technical and non-technical stakeholders

We are proud to offer a competitive compensation package at McKesson as part of our Total Rewards. This is determined by several factors, including performance, experience and skills, equity, regular job market evaluations, and geographical markets. The pay range shown below is aligned with McKesson's pay philosophy, and pay will always be compliant with any applicable regulations. In addition to base pay, other compensation, such as an annual bonus or long-term incentive opportunities may be offered. For more information regarding benefits at McKesson, pleaseclick here.

Our Base Pay Range for this position

$86,600 - $144,400

McKesson has become aware of online recruiting-related scams in which individuals who are not affiliated with or authorized by McKesson are using McKesson's (or affiliated entities, like CoverMyMeds or RxCrossroads) name in fraudulent emails, job postings or social media messages. In light of these scams, please bear the following in mind:
McKesson Talent Advisors will never solicit money or credit card information in connection with a McKesson job application.


McKesson Talent Advisors do not communicate with candidates via online chatrooms or using email accounts such as Gmail or Hotmail. Note that McKesson does rely on a virtual assistant (Gia) for certain recruiting-related communications with candidates.

McKesson job postings are posted on our career site: careers.mckesson.com.

McKesson is an Equal Opportunity Employer

McKesson provides equal employment opportunities to applicants and employees, without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, age, genetic information, or any other legally protected category. For additional information on McKesson's full Equal Employment Opportunity policies, visit our Equal Employment Opportunity page.

McKesson is committed to being an Equal Employment Opportunity Employer and offers opportunities to all job seekers including job seekers with disabilities. If you need a reasonable accommodation to assist with your job search or application for employment, please contact us by sending an email to (United States) Disability_Accommodation@McKesson.com or (Canada) Accessibility@mckesson.ca. Resumes or CVs submitted to this email box will not be accepted.

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