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105 Amgen Senior Systems Engineer Jobs Hiring Near You

Interim HealthCare

Senior Systems Engineer

Greenville, SC · On-site

$115K - $125K/yr

Senior Systems Engineer in Greenville, SC Are you a seasoned Microsoft systems expert ready to lead enterprise-level infrastructure, security, and modernization initiatives in a dynamic, healthcare ...

Castalia Systems

Senior Systems Engineer

Aurora, CO

$106K - $145K/yr

The Senior Systems Engineer will support the assessment, planning, coordination, integration, testing, and implementation of complex systems and system modifications. This position will manage ...

Castalia Systems

Senior Systems Engineer

Aurora, CO · On-site

$106K - $145K/yr

The Senior Systems Engineer will support the assessment, planning, coordination, integration, testing, and implementation of complex systems and system modifications. This position will manage ...

Castalia Systems

Senior Systems Engineer

Aurora, CO · On-site

$106K - $145K/yr

The Senior Systems Engineer will support the assessment, planning, coordination, integration, testing, and implementation of complex systems and system modifications. This position will manage ...

Synapse-ITS

Senior Systems Engineer

Plano, TX · On-site

$97K - $133K/yr

The Senior Systems Engineer is responsible for defining, developing, integrating, and validating system-level architectures for advanced traffic sensing, detection, communication, and control ...

New

Synapse-ITS

Senior Systems Engineer

Plano, TX

$97K - $133K/yr

Description The Senior Systems Engineer is responsible for defining, developing, integrating, and validating system-level architectures for advanced traffic sensing, detection, communication, and ...

New

myIT com

Senior Systems Engineer

Bedford, TX

$93K - $128K/yr

The Senior Systems Engineer Position: This position requires the candidate to independently recognize need for complex equipment repair and replacement, identify user problems promptly, develop ...

myIT.com

Senior Systems Engineer

Bedford, TX · On-site

$93K - $128K/yr

The Senior Systems Engineer Position: This position requires the candidate to independently recognize need for complex equipment repair and replacement, identify user problems promptly, develop ...

myIT com

Senior Systems Engineer

Bedford, TX · On-site

$93K - $128K/yr

The Senior Systems Engineer Position: This position requires the candidate to independently recognize need for complex equipment repair and replacement, identify user problems promptly, develop ...

Systek

Senior Systems Engineer

Gordon, GA · On-site

$98K - $134K/yr

SENIOR SYSTEMS ENGINEER The company is seeking a Senior Systems Engineers to provide SETA support at Ft. Gordon, GA. RESPONSIBILITIES * Assess systems, determine problems, provide solutions to issues ...

New

Systek

Senior Systems Engineer

Gordon, GA · On-site

$98K - $134K/yr

SENIOR SYSTEMS ENGINEER The company is seeking a Senior Systems Engineers to provide SETA support at Ft. Gordon, GA. RESPONSIBILITIES * Assess systems, determine problems, provide solutions to issues ...

New

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Amgen Jobs Information

What is it like to work at Amgen?

Amgen is a biotechnology company that values innovation, collaboration, and patient-centricity, fostering a culture that encourages open communication and teamwork among its employees. The company's research and development teams work in a dynamic environment, often in collaboration with external partners and academia, to develop and deliver life-changing medicines to patients with serious diseases. Working at Amgen may appeal to candidates who are passionate about advancing medical science and improving human health, as the company offers opportunities for professional growth, mentorship, and contributions to groundbreaking research.

What makes Amgen an attractive place to work?

Amgen is a leading biotechnology company that has been at the forefront of innovation in the pharmaceutical industry for decades, with a strong focus on developing life-changing medicines for patients with serious diseases. The company's work environment is characterized by a culture of collaboration, innovation, and scientific excellence, with opportunities for employees to work on cutting-edge projects and contribute to groundbreaking research. As a result, Amgen offers a dynamic and challenging work environment that can provide employees with opportunities for professional growth, development, and impact in the field of biotechnology.

What other companies are hiring for Senior Systems Engineer jobs?

What are the most popular jobs at Amgen?

What are the most popular categories at Amgen?

Infographic showing various Senior Systems Engineer job openings at Amgen in the United States as of August 2026, with employment types broken down into 100% Full Time. Highlights an 80% Physical, and 20% Remote job distribution.

Senior Systems Engineer

Interim HealthCare

Greenville, SC • On-site

$115K - $125K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 14 days ago

Job description

Senior Systems Engineer
in Greenville, SC
Are you a seasoned Microsoft systems expert ready to lead enterprise-level infrastructure, security, and modernization initiatives in a dynamic, healthcare-driven environment? Interim HealthCare is seeking a Sr. Systems Engineer with deep technical expertise, a strategic mindset, and a passion for designing secure, scalable, and resilient solutions.
In this pivotal role, you'll serve as a senior technical authority across Microsoft systems, cloud technologies, cybersecurity, and VOIP-leading architecture decisions, driving infrastructure improvements, and strengthening our overall technology posture. You'll operate as a Tier 3 escalation point, partner with cross-functional teams and franchise stakeholders, and play a key role in shaping the future of our IT environment.
If you thrive in complex environments, enjoy solving high-impact technical challenges, and want to influence how technology supports healthcare delivery at scale, this is the opportunity for you.
Why You'll Enjoy Being Part of Our Team:
  • Competitive Pay: $115,000 - $125,000 per year, based on experience
  • Meaningful impact: Use your technical expertise to design and support systems that directly enable patient care and operational excellence.
  • Supportive Culture: Join a collaborative, family-oriented environment that values innovation, accountability, and continuous improvement.
  • Comprehensive Benefits: Enjoy PTO, holiday pay, medical, dental, and vision coverage, along with 401(k) benefits.

Big-Picture Overview: What You'll Do as a Senior Systems Engineer:
  • Administer and optimize On-Premises Active Directory and Azure AD Connect, ensuring secure hybrid identity, SSO, and efficient replication.
  • Oversee Microsoft 365 services (Exchange, SharePoint, OneDrive, Teams), ensuring reliable collaboration and system performance.
  • Design, implement, and support VMware virtual infrastructures and VOIP systems, focusing on scalability, resilience, and successful migrations.
  • Act as a Tier 3 escalation point for complex technical issues, driving root cause analysis, long-term solutions, and operational improvements.
  • Lead cybersecurity initiatives, including vulnerability mitigation, incident response, and system hardening.
  • Develop and maintain backup, recovery, and disaster recovery strategies to ensure business continuity.
  • Collaborate with internal teams and franchise locations to provide expert guidance, document technical procedures, and support IT project delivery.

Must-Haves for Success in This Role:
  • This will be a full-time, onsite position in Greenville, SC.
  • Bachelor's degree or equivalent experience in a related field.
  • 5+ years of progressive experience as a Senior Systems Engineer.
  • 10-15 years as a Microsoft Systems Engineer or in a similar technical role.
  • 10+ years managing VMware virtual infrastructures and VOIP environments, including migration leadership.
  • Strong expertise in cybersecurity principles, risk mitigation, and enterprise system hardening.
  • Exceptional problem-solving, analytical, and conceptual skills with the ability to influence technical decisions.
  • Ability to work independently while effectively collaborating with leadership, stakeholders, and cross-functional teams.

Why Work for Interim HealthCare?
Founded in 1966, Interim HealthCare is the nation's first home health company and a trusted leader in compassionate, patient-centered care. With 300+ locations nationwide, we foster a family-oriented culture that values every team member. As a Senior Systems Engineer, you'll play a critical role in supporting and advancing the technology that enables exceptional care delivery-ensuring systems are secure, reliable, and built for the future.
Interim HealthCare is an equal-opportunity employer committed to diversity and inclusion in the workplace. We prohibit discrimination and harassment of any kind based on race, color, sex, religion, sexual orientation, national origin, disability, genetic information, pregnancy, or any other protected characteristic as outlined by federal, state, or local laws.
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