12 Illumina Instrumentation Engineer Jobs Hiring Near You

What if the work you did every day could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life‑changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world‑changing projects, you will do more and become more than you ever thought possible.

The Equipment Engineer I supports the reliability, sustainment, troubleshooting, and continuous improvement of manufacturing equipment used in Flow Cell Manufacturing. Working closely with Manufacturing Operations, Process Engineering, Equipment Engineering, and other cross‑functional teams, this role helps sustain automated production equipment while supporting improvements in safety, quality, reliability, yield, and manufacturing efficiency. This is a highly hands‑on engineering role with significant time spent on the manufacturing floor troubleshooting equipment, supporting production operations, investigating failures, implementing equipment improvements, and contributing to equipment reliability efforts. Working within established procedures and guidelines, and with appropriate oversight, the Equipment Engineer I supports equipment sustainment and upgrades while troubleshooting technical issues and escalating complex problems to senior engineers or management as appropriate. The role also contributes to technical documentation, equipment performance analysis, training and knowledge‑sharing activities, and continuous improvement efforts, communicating findings through reports, presentations, and cross‑functional collaboration.

• Support manufacturing operations through equipment troubleshooting, equipment sustainment, technical problem solving, and engineering improvements.
• Assist with preventive maintenance optimization, calibration, qualification, equipment upgrades, reliability improvement activities, and monitoring of basic equipment performance indicators.
• Troubleshoot mechanical, electrical, pneumatic, controls, automation, and process‑related issues using structured problem‑solving methods, recognizing when to seek guidance and escalating complex technical issues to senior engineers or management.
• Support automated manufacturing systems, including robotics, machine vision, motion control, PLCs, sensors, and related automation technologies.
• Use electrical schematics, multimeters, and other diagnostic tools to troubleshoot electrical control panels, wiring, instrumentation, and equipment issues.
• Develop and maintain technical documentation, including SOPs, work instructions, preventive maintenance procedures, troubleshooting guides, and training materials; support training and knowledge‑sharing activities.
• Partner with Manufacturing Operations, Process Engineering, Equipment Engineering, Quality, Validation, R&D, suppliers, and other cross‑functional teams to support investigations, equipment improvements, reliability efforts, and safety‑related activities while providing clear technical observations and supporting data.
• Learn and apply engineering standards, best practices, and structured problem‑solving techniques while developing technical expertise with guidance from senior engineers and management.

• Bachelor's degree in Mechanical Engineering, Electrical Engineering, Electronics Engineering, Mechatronics Engineering, Engineering Technology, or a related technical discipline with 0-2 years of experience; or equivalent technical education and relevant hands‑on experience.

• Mechanical and electrical/electronics aptitude demonstrated through academic projects, internships, laboratory work, or relevant industry experience.
• Basic knowledge of automated manufacturing systems, industrial automation, equipment controls, robotics, machine vision, and motion control technologies.
• Ability to read and interpret electrical schematics, wiring diagrams, mechanical drawings, pneumatic diagrams, and technical documentation.
• Familiarity with common measurement, inspection, and troubleshooting tools, such as multimeters, calipers, gauges, and similar diagnostic equipment, gained through coursework, laboratory work, internships, or industry experience.
• Familiarity with electrical control panels, instrumentation, industrial communication interfaces, and common industrial sensors used in automated equipment environments.
• Familiarity with collecting, organizing, and interpreting equipment or process data to support troubleshooting and performance improvement activities.
• Experience with Microsoft Office applications and basic data analysis tools.
• Understanding of safe work practices when working with mechanical, electrical, laboratory, manufacturing, or other technical systems and environments.

• Troubleshooting, analytical, and problem‑solving skills demonstrated through academic projects, internships, laboratory work, or prior experience.
• Effective verbal and written communication skills, including the ability to communicate technical information and project updates to manufacturing and engineering teams.
• Ability to manage assigned areas of equipment responsibility and contribute solutions within established systems and processes under appropriate guidance while collaborating across cross‑functional teams.
• Comfortable working in a manufacturing environment with significant hands‑on equipment support while balancing documentation and improvement activities.
• Ability to manage multiple priorities in a fast‑paced manufacturing environment.
• Commitment to safety, quality, documentation, and continuous improvement.

• Flexibility to support manufacturing schedules outside the traditional Monday‑Friday workweek, including fixed five consecutive-day schedules (e.g., Sunday‑Thursday or Tuesday‑Saturday).
• Exposure to automated manufacturing equipment through academic projects, internships, research, laboratory work, or production environments.
• Familiarity with semiconductor or other highly automated manufacturing systems is a plus.
• Exposure to industrial automation technologies, including PLCs, PC‑based control systems, robotics, machine vision, motion control, industrial sensors, scripting/programming languages (e.g., Python), statistical analysis tools (e.g., JMP or Minitab), manufacturing databases, maintenance management systems (MMS/CMMS), equipment tracking tools, manufacturing support systems, or technical documentation development.
• Exposure to engineering design, CAD, simulation, or analytical software through coursework, projects, internships, or research experience.

Listed responsibilities are intended to describe the general nature and level of work performed and are not an exhaustive list of all duties. Responsibilities may change based on business needs and organizational priorities.

The estimated base salary range for the Equipment Engineer I role based in the United States of America is: $68,400 - $102,600. Should the level or location of the role change during the hiring process, the applicable base pay range may be updated accordingly. The range reflects long‑term growth in the role; therefore, most candidates are hired between the minimum and middle of the range. Placement depends on experience, skills, location, and internal equity.

We offer a wide range of benefits as innovative as our work, including access to genomics sequencing, family planning, health/dental/vision, retirement benefits, and paid time off.

Additionally, all employees are eligible for one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package.

We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero‑net gap in pay, regardless of gender, ethnicity, or race.

We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility.

We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information.

Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws.

If you require accommodation to complete the application or interview process, please contact accommodations@illumina.com.

Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process.

The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants.

This role is not eligible for visa sponsorship.

The potential of genomics to change the world is unparalleled. At Illumina, we are leading the way. Our technology empowers researchers and clinicians globally to improve cancer treatments, change the course of diseases, protect the environment, and fight food insecurity. We are made up of dedicated professionals, all‑in on creating a better world – and we need every skill set on our path to making genomics useful for all. Learn more about life at Illumina.