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Weekend Rn Jobs in Lexington, KY (NOW HIRING)

HealthSouth

Registered Nurse

Lexington, KY · On-site

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

$10,000 sign on bonus for FT positions Competitive rates for Weekend Options. Registered Nurse Career Opportunity - Full Time, Part Time and Weekend positions available Encompass Health: Where ...

Signature HealthCARE, LLC

Registered Nurse (RN)

Lexington, KY · On-site

$42.94/hr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

We are looking for RN candidates who thrive on delivering excellent care, enjoy being part of a ... Shift Differentials and Weekend Enhanced Hourly Rates * Tuition Forgiveness/Education Reimbursement

Signature HealthCARE

Registered Nurse (RN)

Lexington, KY · On-site

$42.94/hr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

We are looking for RN candidates who thrive on delivering excellent care, enjoy being part of a ... Shift Differentials and Weekend Enhanced Hourly Rates * Tuition Forgiveness/Education Reimbursement

Lifepoint Health

Registered Nurse (RN) - PreOp

Versailles, KY

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Registered Nurse (RN) - PreOp Job Type: Full Time | Days $10,000 Sign On Bonus, 2 year commitment ... Monday - Friday, 6a-2:30p No Call, No Weekends, No holidays Your experience matters At Centerpoint ...

Signature HealthCARE

Registered Nurse (RN)

Harrodsburg, KY · On-site

$45.25/hr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

We are looking for RN candidates who thrive on delivering excellent care, enjoy being part of a ... Shift Differentials and Weekend Enhanced Hourly Rates * Tuition Forgiveness/Education Reimbursement

Signature HealthCARE, LLC

Registered Nurse (RN)

Harrodsburg, KY · On-site

$45.25/hr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

We are looking for RN candidates who thrive on delivering excellent care, enjoy being part of a ... Shift Differentials and Weekend Enhanced Hourly Rates * Tuition Forgiveness/Education Reimbursement

Signature HealthCARE

Registered Nurse (RN)

Danville, KY · On-site

$40.20/hr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

We are looking for RN candidates who thrive on delivering excellent care, enjoy being part of a ... Shift Differentials and Weekend Enhanced Hourly Rates * Tuition Forgiveness/Education Reimbursement

Lifepoint Health

Registered Nurse (RN) - PreOp

Versailles, KY · On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Registered Nurse (RN) - PreOp Job Type: Full Time | Days $10,000 Sign On Bonus, 2 year commitment ... Monday - Friday, 6a-2:30p No Call, No Weekends, No holidays Your experience matters At Centerpoint ...

Baptist Health

Registered Nurse

Lexington, KY · On-site

  • Medical

  • Dental

  • Vision

  • Life

  • PTO

Customer relations and a healing environment. * On call requirement weekends/holidays picked by ... Current RN licensure and work permit in Kentucky. * Bachelor's or an associate degree in nursing ...

Signature HealthCARE, LLC

Registered Nurse (RN)

Lexington, KY · On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

We are looking for RN candidates who thrive on delivering excellent care, enjoy being part of a ... Shift Differentials and Weekend Enhanced Hourly Rates * Tuition Forgiveness/Education Reimbursement

Mission Hospital

Registered Nurse

Frankfort, KY · On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Job Summary and Qualifications Full time (Monday - Friday, days), no nights, no on call, no weekends, no holidays Seeking a Registered Nurse RN for our practice who provides clinical expertise to ...

PRIDE Health

Travel Nurse RN - Home Health

Richmond, KY · On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

Participate in required on-call and weekend coverage. * Manage daily visits while meeting the 25 ... Active RN license * 3+ years of Home Health experience * 3+ years of OASIS experience * Strong ...

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Showing results 41-60

All JobsRn JobsWeekend Rn JobsWeekend Rn Jobs in Lexington, KY

Weekend Rn information

See Lexington, KY salary details

$25

$39

$66

How much do weekend rn jobs pay per hour?

As of Aug 15, 2026, the average hourly pay for weekend rn in Lexington, KY is $39.87, according to ZipRecruiter salary data. Most workers in this role earn between $31.64 and $46.02 per hour, depending on experience, location, and employer.

What does a Weekend RN do?

As a weekend RN, you take shifts on the weekend when other nurses are unavailable, allowing hospitals and other care facilities to provide continuity of care and remain open 24/7. This is usually a part-time position, with most weekend RN's working two 8-12 hour shifts Saturday-Sunday each week. Some facilities also count Friday as a weekend day and offer a three-shift schedule instead. In this role, you may make patient visits, answer telephone calls to provide remote healthcare and address any medical emergencies that occur during your shift as a weekend nurse. As an RN, weekend work usually focuses on hospitals and hospice facilities, but you may find positions that involve traveling to visit patients outside of a clinical setting.

What are some unique challenges and rewards of working as a Weekend RN compared to a standard weekday nursing position?

Weekend RNs often face a distinct set of challenges, including managing higher patient-to-nurse ratios and handling more acute or urgent cases, as there may be fewer staff and support services available on weekends. However, this role also offers unique rewards, such as greater autonomy, opportunities to hone critical thinking and decision-making skills, and often a more flexible schedule or additional compensation. Weekend RNs typically collaborate closely with a dedicated core team, fostering strong teamwork and communication. This experience can be valuable for career advancement, as it demonstrates adaptability and strong clinical competence in a fast-paced environment.

What is the difference between Weekend Rn vs Weekend Lpn?

AspectWeekend RnWeekend Lpn
Required CredentialsRegistered Nurse license (RN)Licensed Practical Nurse license (LPN)
Work EnvironmentHospitals, clinics, long-term care facilitiesLong-term care, nursing homes, clinics
Employer & Industry UsageHospitals, healthcare agenciesLong-term care facilities, nursing homes
Common Search & Comparison IntentUnderstanding RN roles on weekendsUnderstanding LPN roles on weekends

Weekend Rn and Weekend Lpn roles differ mainly in credentials, with RNs holding a registered nurse license and LPNs holding a practical nurse license. RNs typically perform more complex medical tasks and have broader responsibilities, while LPNs focus on basic patient care. Both roles are common in healthcare settings that require weekend coverage, but RNs generally have more advanced training and scope of practice.

What is a Weekend RN?

A Weekend RN is a registered nurse who primarily works during the weekends, often covering shifts on Saturdays and Sundays. These nurses provide patient care, administer medications, monitor patient progress, and collaborate with doctors and other healthcare staff. Weekend RNs may work in hospitals, nursing homes, or other healthcare facilities, and their schedules are designed to ensure continuous high-quality care throughout the week. Weekend shifts can sometimes offer higher pay rates or shift differentials due to the non-traditional hours.

What are the key skills and qualifications needed to thrive as a Weekend RN, and why are they important?

To thrive as a Weekend RN, you need current RN licensure, strong clinical assessment skills, and experience in acute or long-term care settings. Familiarity with electronic health record (EHR) systems and up-to-date certifications such as BLS or ACLS are often required. Excellent time management, adaptability, and communication skills are essential for managing patient care during typically higher-acuity weekend shifts. These competencies ensure patient safety, efficient care delivery, and effective teamwork when staffing levels and resources may be limited.
More about Weekend Rn jobs

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What cities near Lexington, KY are hiring for Weekend Rn jobs?

Cities near Lexington, KY with the most Weekend Rn job openings:

Weekend Rn jobs near you
Infographic showing various Weekend Rn job openings in Lexington, KY as of August 2026, with employment types broken down into 11% As Needed, 69% Full Time, 17% Part Time, and 3% Temporary. Highlights an 97% In-person, and 3% Remote job distribution, with an average salary of $82,935 per year, or $39.9 per hour.

Registered Nurse (RN) - Per Diem, Nights

Select Specialty Hospital - Central Kentucky

Danville, KY • On-site

$45/hr

Per diem

Re-posted 14 days ago

Job description

Overview
Position: Registered Nurse (RN)
Location: Danville, KY
Schedule: Night shift - PRN/ Per Diem/ As Needed
Compensation: $45.00 per hour
plus up to $10.50 additional per hour for night and weekend shifts
Sign-on bonus: $5,000
Select Specialty Hospital is a critical illness recovery hospital committed to providing world-class inpatient post-ICU services to chronic, critically ill patients who require extended healing and recovery. We help patients during some of the most vulnerable, painful moments of their lives - and Registered Nurses (RNs) play a central role in providing compassionate, excellent treatment every step of the way.
At our company, we support your career growth and personal well-being.
  • Start Strong: Extensive and thorough Registered Nurse (RN) orientation program to ensure a smooth transition into our setting.
  • Flexible Scheduling: Minimum per diem requirement of 4 shifts in a 6-week period.
  • Opportunity for Advancement: Demonstrate your skills and dedication which could lead to potential full-time opportunities.
  • Your Impact Matters: Join a team of over 44,000 nationwide committed to providing exceptional care.

Responsibilities
Responsibilities
  • Receive admissions and/or transfers to the unit
  • Initial and ongoing systematic patient assessment
  • Timely and accurate documentation using appropriate systems
  • Interpret assessment/diagnostic data including labs and telemetry
  • Ensure medical orders are transcribed and processed accurately
  • Competence in Rapid Response and code events
  • Instruct and counsel patients/families
  • Performs other duties as assigned

Qualifications
Minimum Qualifications:
  • Valid State RN License
  • BLS is required at hire.
  • ACLS is required at hire.

Preferred Qualifications:
  • Clinical experience

Apply