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Weekend Prn Rn Jobs in Durham, NC (NOW HIRING)

AMSURG

Registered Nurse-PRN

Cary, NC · On-site

PRN Endoscopy Registered Nurse (RN) Location: Wake Endoscopy Center-Cary - Cary, NC Position Type: PRN / AsNeeded About the Role Wake Endoscopy Center-Cary is seeking a PRN Endoscopy Registered Nurse ...

PRN Healthcare

Travel CVPICU RN

Durham, NC · On-site

PRN Healthcare is seeking a travel nurse RN CVPICU for a travel nursing job in Durham, North Carolina. & Requirements * Specialty: CVPICU * Discipline: RN * Start Date: 09/08/2026 * Duration: 13 ...

PRN Healthcare

Travel CVPICU RN

Durham, NC · On-site

PRN Healthcare is seeking a travel nurse RN CVPICU for a travel nursing job in Durham, North Carolina. & Requirements * Specialty: CVPICU * Discipline: RN * Start Date: 09/08/2026 * Duration: 13 ...

PRN Healthcare

Travel CVPICU RN

Durham, NC · On-site

PRN Healthcare is seeking a travel nurse RN CVPICU for a travel nursing job in Durham, North Carolina. & Requirements * Specialty: CVPICU * Discipline: RN * Start Date: 09/08/2026 * Duration: 13 ...

PRN Healthcare

Travel CVPICU RN

Durham, NC · On-site

PRN Healthcare is seeking a travel nurse RN CVPICU for a travel nursing job in Durham, North Carolina. & Requirements * Specialty: CVPICU * Discipline: RN * Start Date: 09/08/2026 * Duration: 13 ...

PRN Healthcare

Travel Telemetry RN

Burlington, NC · On-site

$1.6K - $2.3K/wk

PRN Healthcare is seeking a travel nurse RN Med Surg / Telemetry for a travel nursing job in Burlington, North Carolina. & Requirements * Specialty: Med Surg / Telemetry * Discipline: RN * Start Date ...

PRN Healthcare

Travel Ortho RN

Burlington, NC · On-site

PRN Healthcare is seeking a travel nurse RN Orthopedics for a travel nursing job in Burlington, North Carolina. & Requirements * Specialty: Orthopedics * Discipline: RN * Start Date: 09/14/2026

PRN Healthcare

Travel CVPICU RN

Durham, NC · On-site

PRN Healthcare is seeking a travel nurse RN CVPICU for a travel nursing job in Durham, North Carolina. & Requirements * Specialty: CVPICU * Discipline: RN * Start Date: 09/08/2026 * Duration: 13 ...

PRN Healthcare

Travel CVPICU RN

Durham, NC · On-site

PRN Healthcare is seeking a travel nurse RN CVPICU for a travel nursing job in Durham, North Carolina. & Requirements * Specialty: CVPICU * Discipline: RN * Start Date: 09/08/2026 * Duration: 13 ...

PRN Healthcare

Travel Oncology RN

Raleigh, NC · On-site

$2.0K - $2.8K/wk

PRN Healthcare is seeking a travel nurse RN Oncology for a travel nursing job in Raleigh, North Carolina. & Requirements * Specialty: Oncology * Discipline: RN * Start Date: 09/21/2026 * Duration: 13 ...

PRN Healthcare

Travel ER RN

Burlington, NC · On-site

PRN Healthcare is seeking a travel nurse RN ED - Emergency Department for a travel nursing job in Burlington, North Carolina. & Requirements * Specialty: ED - Emergency Department * Discipline: RN * ...

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Weekend Prn Rn information

See Durham, NC salary details

$18

$35

$52

How much do weekend prn rn jobs pay per hour?

As of Sep 3, 2026, the average hourly pay for weekend prn rn in Durham, NC is $35.24, according to ZipRecruiter salary data. Most workers in this role earn between $28.12 and $40.67 per hour, depending on experience, location, and employer.

What is a Weekend PRN RN?

A Weekend PRN RN (As Needed Registered Nurse) is a nursing position where the nurse works primarily on weekends and on an as-needed basis. These roles are typically found in hospitals, nursing homes, and healthcare facilities that require additional weekend staffing. PRN nurses do not usually have a set schedule and may be called to fill in for staff shortages. This role offers flexibility but may not guarantee a certain number of hours. Weekend PRN RNs must still meet licensing and certification requirements like full-time nurses.

What are the typical shift expectations and workload for a Weekend PRN RN?

Weekend PRN RN positions usually require nurses to work flexible hours on Saturdays and Sundays, with potential opportunities for additional shifts based on staffing needs. The workload can vary each weekend, depending on patient census and acuity, so adaptability is important. These roles often involve collaborating with a leaner weekend team, requiring strong teamwork and autonomy. While you may not have a set schedule every week, PRN positions can offer valuable hands-on experience and are ideal for nurses seeking flexibility or supplemental income.

What are the key skills and qualifications needed to thrive in the Weekend PRN RN position, and why are they important?

To thrive as a Weekend PRN RN, you need a current RN license, strong clinical assessment abilities, and experience in acute or long-term care settings. Familiarity with electronic health record (EHR) systems, medication administration protocols, and facility-specific safety procedures is important. Flexibility, excellent communication, and the ability to work independently are valuable soft skills for managing varied shifts and patient needs. These competencies ensure that you can provide high-quality care and respond effectively to weekend staffing and patient demands.

Do PRN registered nurses have to work weekends?

PRN registered nurses are scheduled on an as-needed basis and are not typically required to work weekends unless assigned to weekend shifts. Their work schedule depends on the facility's staffing needs and the nurse's availability, often offering flexibility. However, some PRN positions may include weekend shifts if the facility requires coverage during those times.

What are the most commonly searched types of Prn Rn jobs in Durham, NC?

The most popular types of Prn Rn jobs in Durham, NC are:

What are popular job titles related to Weekend Prn Rn jobs in Durham, NC?

For Weekend Prn Rn jobs in Durham, NC, the most frequently searched job titles are:

What job categories do people searching Weekend Prn Rn jobs in Durham, NC look for?

The top searched job categories for Weekend Prn Rn jobs in Durham, NC are:

What cities near Durham, NC are hiring for Weekend Prn Rn jobs?

Cities near Durham, NC with the most Weekend Prn Rn job openings:

Weekend Prn Rn jobs near you
Infographic showing various Weekend Prn Rn job openings in Durham, NC as of August 2026, with employment types broken down into 1% As Needed, 68% Full Time, 27% Part Time, 1% Temporary, 2% Contract, and 1% Nights. Highlights an 93% Physical, 1% Hybrid, and 6% Remote job distribution, with an average salary of $73,308 per year, or $35.2 per hour.

Registered Nurse-PRN

AMSURG

Cary, NC • On-site

Part-time

Re-posted 2 days ago

AmSurg rating

6.2

Company rating: 6.2 out of 10

Based on 24 frontline employees who took The Breakroom Quiz

Job description

PRN Endoscopy Registered Nurse (RN)

Location: Wake Endoscopy Center-Cary – Cary, NC
Position Type: PRN / AsNeeded

About the Role

Wake Endoscopy Center-Cary is seeking a PRN Endoscopy Registered Nurse (RN) to support safe, efficient, and compassionate patient care throughout the endoscopy process. This is an excellent opportunity for nurses seeking flexible, asneeded work in a focused procedural environment.

What You’ll Do

  • Provide nursing care throughout the endoscopy process, from patient preparation through postprocedure monitoring
  • Support patient care activities in the procedure room and collaborate with physicians and the care team
  • Verify patient identity and procedure using approved safety and timeout protocols
  • Prepare procedure rooms, equipment, instruments, and supplies based on patient and procedure needs
  • Assist with safe patient positioning and continuous monitoring during procedures
  • Administer medications per physician orders
  • Accurately document patient care and procedural details in accordance with policy
  • Handle, label, and log tissue specimens according to established procedures
  • Ensure instruments and supplies meet highlevel disinfection and sterilization standards
  • Support efficient room turnover and appropriate use of supplies
  • Provide patient education, comfort, and reassurance while maintaining privacy and dignity
  • Perform other duties as assigned

What We’re Looking For

  • Strong clinical judgment and attention to detail
  • Ability to work efficiently in a procedural or fastpaced environment
  • Excellent communication and teamwork skills
  • Commitment to patient safety and quality care

Preferred Qualifications

  • Active Registered Nurse (RN) license
  • Basic Life Support (BLS) required
  • Advanced Cardiac Life Support (ACLS) preferred
  • Prior experience in endoscopy, GI, procedural, surgical, or perioperative nursing preferred

Why Join Wake Endoscopy Center-Cary (PRN)

  • Flexible, asneeded scheduling
  • Procedural nursing environment (no inpatient floor assignments)
  • Supportive, teambased culture
  • Opportunity to maintain worklife balance while using specialized skills

What AmSurg employees say

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