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Weekend Infusion Rn Jobs in St Louis, MO (NOW HIRING)

SSM Health

Registered Nurse - Infusion

Saint Louis, MO · On-site

  • Medical

  • Retirement

Certified Registered Nurse Infusion (CRNI) - Infusion Nurses Certification Corporation (INCC) * Or * Chemotherapy Biotherapy Certificate (ONS/ONCC) - Oncology Nursing Society (ONS) * Or

Option Care Health

Infusion Nurse - St. Louis

Saint Louis, MO · On-site

$36 - $47.75/hr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

An Infusion Nurse II is a licensed registered nurse who coordinates and provides intermediate direct patient care to patients in the home, or in an alternate infusion suite, to ensure patient safety ...

Option Care Health

Infusion Nurse - St. Louis

Fenton, MO · On-site

$35.50 - $47/hr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

An Infusion Nurse II is a licensed registered nurse who coordinates and provides intermediate direct patient care to patients in the home, or in an alternate infusion suite, to ensure patient safety ...

Option Care

Infusion Nurse - St. Louis

Fenton, MO

$35.25 - $46.75/hr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

An Infusion Nurse II is a licensed registered nurse who coordinates and provides intermediate direct patient care to patients in the home, or in an alternate infusion suite, to ensure patient safety ...

Option Care

Infusion Nurse - St. Louis

Saint Peters, MO · On-site

$35.50 - $46.75/hr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

An Infusion Nurse II is a licensed registered nurse who coordinates and provides intermediate direct patient care to patients in the home, or in an alternate infusion suite, to ensure patient safety ...

Option Care Health

Infusion Nurse - St. Louis

Saint Peters, MO · On-site

$35.50 - $46.75/hr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

An Infusion Nurse II is a licensed registered nurse who coordinates and provides intermediate direct patient care to patients in the home, or in an alternate infusion suite, to ensure patient safety ...

Option Care

Infusion Nurse - St. Louis

Saint Louis, MO

$36 - $47.75/hr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

An Infusion Nurse II is a licensed registered nurse who coordinates and provides intermediate direct patient care to patients in the home, or in an alternate infusion suite, to ensure patient safety ...

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Showing results 41-60

All JobsInfusion Rn JobsWeekend Infusion Rn JobsWeekend Infusion Rn Jobs in St. Louis, MO

Weekend Infusion Rn information

See St Louis, MO salary details

$11

$44

$80

How much do weekend infusion rn jobs pay per hour?

As of Aug 16, 2026, the average hourly pay for weekend infusion rn in St. Louis, MO is $44.69, according to ZipRecruiter salary data. Most workers in this role earn between $35.29 and $48.85 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in the Weekend Infusion RN position, and why are they important?

Weekend Infusion RNs require a current RN license, strong IV therapy skills, and experience in administering infusion medications safely. Familiarity with infusion pumps, electronic health records (EHR), and up-to-date certifications like Basic Life Support (BLS) or Advanced Cardiac Life Support (ACLS) are typically expected. Excellent organizational skills, compassionate bedside manner, and the ability to work independently are valuable soft skills in this setting. Mastery of these competencies ensures reliable, high-quality patient care during weekends when resources may be limited.

What is a Weekend Infusion RN?

A Weekend Infusion RN is a registered nurse who administers intravenous (IV) therapies, medications, and treatments to patients during weekends. They work in outpatient clinics, hospitals, or home health settings, ensuring safe and effective infusion therapy. Responsibilities include monitoring patients for reactions, maintaining IV access, and educating patients about their treatments. This role requires strong IV skills, attention to detail, and the ability to work independently. It is ideal for nurses seeking flexible weekend hours while providing critical care to patients requiring infusion services.

What are the typical responsibilities and work environment for a Weekend Infusion RN?

As a Weekend Infusion RN, you will primarily administer intravenous medications, monitor patients for side effects, and educate them about their treatment plans—often in outpatient clinics, specialty centers, or sometimes patients' homes. The work environment is usually focused and patient-centered, with collaboration between RNs, pharmacists, and physicians, especially for complex cases. Since the role is concentrated on weekends, you may work more independently and manage a smaller, more specialized patient load. This schedule offers flexibility and the opportunity to focus on building relationships with patients receiving ongoing infusion therapy.

Do infusion nurses get paid more?

Infusion nurses often earn higher wages compared to general nursing roles due to specialized skills in administering IV therapies and managing complex patient needs. Their compensation can also increase with experience, certifications, and working in high-demand settings or during overtime and weekend shifts. However, pay varies by location, employer, and individual qualifications.

What are the most commonly searched types of Infusion Rn jobs in St. Louis, MO?

The most popular types of Infusion Rn jobs in St. Louis, MO are:

What are popular job titles related to Weekend Infusion Rn jobs in St. Louis, MO?

For Weekend Infusion Rn jobs in St. Louis, MO, the most frequently searched job titles are:

What job categories do people searching Weekend Infusion Rn jobs in St. Louis, MO look for?

The top searched job categories for Weekend Infusion Rn jobs in St. Louis, MO are:

What cities near St. Louis, MO are hiring for Weekend Infusion Rn jobs?

Cities near St. Louis, MO with the most Weekend Infusion Rn job openings:

Weekend Infusion Rn jobs near you
Infographic showing various Weekend Infusion Rn job openings in St. Louis, MO as of August 2026, with employment types broken down into 1% As Needed, 70% Full Time, 25% Part Time, 3% Contract, and 1% Nights. Highlights an 95% Physical, 1% Hybrid, and 4% Remote job distribution, with an average salary of $92,951 per year, or $44.7 per hour.

Registered Nurse - Infusion

SSM Health

Saint Louis, MO • On-site

Part-time

Medical

Re-posted 3 days ago

SSM Health rating

6.8

Company rating: 6.8 out of 10

Based on 547 frontline employees who took The Breakroom Quiz

495th of 887 rated healthcare providers

Job description

It's more than a career, it's a calling
MO-SSM Health St. Mary's Hospital - St. Louis
Worker Type:
Regular
Job Highlights:
Department: Infusion
Schedule : 8AM- 4PM Mon-Fri
Preferred Qualifications: Infusion/chemotherapy experience
Benefits: Competitive, affordable health insurance including but not limited to:
  • Getting paid every day!
  • Access up to $5,250 in tuition coverage per year
  • Paid maternity & paternity coverage
  • Adoption assistance
  • Various competitive health insurance options & wellness plans
  • Retirement benefits including employer matching plans
  • Long & short-term disability
  • Employee assistance programs (EAP)

Job Summary:
Performs the primary functions of a registered nurse in assessing, diagnosing, planning, implementing and evaluating the care of all assigned patients.
Job Responsibilities and Requirements:
PRIMARY RESPONSIBILITIES
  • Supports the care of the patient and assesses and addresses the needs of the patient/family.
  • Works collaboratively with other interprofessional team members in resolving patient/family problems, concerns and issues.
  • Collaborates with other departments as needed to establish the patient/family treatment plan.
  • Individualizes, implements, evaluates or updates the plan of care and patient educational needs regarding vascular access.
  • Possesses the ability to complete intravenous insertion and assessment to include peripheral and central line access.
  • Utilizes equipment such as point of care ultrasound equipment and intravenous infusion pumps as appropriate.
  • Demonstrates proper interpretation of department specific policies and related laboratory results to safely manage specific patient needs.
  • Implements, monitors and records patient care and communicates patient condition as appropriate. Takes appropriate actions to unanticipated changes in patient condition.
  • Utilizes the Electronic Health Record (EHR) to access treatment and therapy plans.
  • Applies the existing body of evidence-based practice and scientific knowledge in health care to nursing practice, ensuring that nursing care is delivered based on patient's age-specific needs and clinical needs as described in the department's scope of service.
  • Works in a constant state of alertness and safe manner.
  • Performs other duties as assigned.

EDUCATION
  • Graduate of accredited school of nursing or education equivalency for licensing

EXPERIENCE
  • No experience required

PHYSICAL REQUIREMENTS
  • Constant use of speech to share information through oral communication.
  • Constant standing and walking.
  • Frequent lifting/carrying and pushing/pulling objects weighing 0-25 lbs.
  • Frequent sitting, reaching and keyboard use/data entry.
  • Frequent use of vision and depth perception for distances near (20 inches or less) and far (20 feet or more) and to identify and distinguish colors.
  • Frequent use of smell to detect/recognize odors.
  • Frequent use of hearing to receive oral communication, distinguish body sounds and/or hear alarms, malfunctioning machinery, etc.
  • Occasional lifting/carrying and pushing/pulling objects weighing 25-50 lbs.
  • Occasional lifting/moving of patients.
  • Occasional bending, stooping, kneeling, squatting, twisting, gripping and repetitive foot/leg and hand/arm movements.
  • Occasional driving.
  • Rare crawling and running.

REQUIRED PROFESSIONAL LICENSE AND/OR CERTIFICATIONS
State of Work Location: Illinois
  • Basic Life Support HealthCare Provider (BLS HCP) - American Heart Association (AHA)
  • And
  • Registered Professional Nurse (RN) - Illinois Department of Financial and Professional Regulation (IDFPR)
  • And
  • Advanced Oncology Certified Nurse (AOCN) - Oncology Nursing Certification Corporation (ONCC)
  • Or
  • Anticoagulation Therapy Management Certification - University of Southern Indiana College of Nursing and Health Professions
  • Or
  • Certified Anticoagulation Care Provider (CACP) - National Certification Board for Anticoagulation Providers (NCBAP)
  • Or
  • Certified Oncology Nurse (OCN) - Oncology Nursing Certification Corporation (ONCC)
  • Or
  • Certified Pediatric Hematology Oncology Nurse (CPHON) - Oncology Nursing Certification Corporation (ONCC)
  • Or
  • Certified Pediatric Oncology Nurse (CPON) - Oncology Nursing Certification Corporation (ONCC)
  • Or
  • Certified Registered Nurse Infusion (CRNI) - Infusion Nurses Certification Corporation (INCC)
  • Or
  • Chemotherapy Biotherapy Certificate (ONS/ONCC) - Oncology Nursing Society (ONS)
  • Or
  • Chemotherapy Immunotherapy Certificate (ONS/ONCC) - Oncology Nursing Society (ONS)
  • Or
  • Fundamentals of Chemotherapy Immunotherapy Certificate - Oncology Nursing Society (ONS)
  • Or
  • INS Fundamentals of Infusion Therapy (FIT) certification - Infusion Nurses Society (INS)
  • Or
  • Vascular Access Certification (VA-BC) - Vascular Access Certification Corporation (VACC)

State of Work Location: Missouri
  • Basic Life Support HealthCare Provider (BLS HCP) - American Heart Association (AHA)
  • And
  • Registered Nurse (RN) - Missouri Division of Professional Registration
  • Or
  • Registered Nurse (RN) Issued by Compact State
  • And
  • Advanced Oncology Certified Nurse (AOCN) - Oncology Nursing Certification Corporation (ONCC)
  • Or
  • Anticoagulation Therapy Management Certification - University of Southern Indiana College of Nursing and Health Professions
  • Or
  • Certified Anticoagulation Care Provider (CACP) - National Certification Board for Anticoagulation Providers (NCBAP)
  • Or
  • Certified Oncology Nurse (OCN) - Oncology Nursing Certification Corporation (ONCC)
  • Or
  • Certified Pediatric Hematology Oncology Nurse (CPHON) - Oncology Nursing Certification Corporation (ONCC)
  • Or
  • Certified Pediatric Oncology Nurse (CPON) - Oncology Nursing Certification Corporation (ONCC)
  • Or
  • Certified Registered Nurse Infusion (CRNI) - Infusion Nurses Certification Corporation (INCC)
  • Or
  • Chemotherapy Biotherapy Certificate (ONS/ONCC) - Oncology Nursing Society (ONS)
  • Or
  • Chemotherapy Immunotherapy Certificate (ONS/ONCC) - Oncology Nursing Society (ONS)
  • Or
  • Fundamentals of Chemotherapy Immunotherapy Certificate - Oncology Nursing Society (ONS)
  • Or
  • INS Fundamentals of Infusion Therapy (FIT) certification - Infusion Nurses Society (INS)
  • Or
  • Vascular Access Certification (VA-BC) - Vascular Access Certification Corporation (VACC)

State of Work Location: Oklahoma
  • Basic Life Support HealthCare Provider (BLS HCP) - American Heart Association (AHA)
  • And
  • Registered Nurse (RN) Issued by Compact State
  • And
  • Registered Nurse (RN) - Oklahoma Board of Nursing (OBN)
  • And
  • Advanced Oncology Certified Nurse (AOCN) - Oncology Nursing Certification Corporation (ONCC)
  • Or
  • Anticoagulation Therapy Management Certification - University of Southern Indiana College of Nursing and Health Professions
  • Or
  • Certified Anticoagulation Care Provider (CACP) - National Certification Board for Anticoagulation Providers (NCBAP)
  • Or
  • Certified Oncology Nurse (OCN) - Oncology Nursing Certification Corporation (ONCC)
  • Or
  • Certified Pediatric Hematology Oncology Nurse (CPHON) - Oncology Nursing Certification Corporation (ONCC)
  • Or
  • Certified Pediatric Oncology Nurse (CPON) - Oncology Nursing Certification Corporation (ONCC)
  • Or
  • Certified Registered Nurse Infusion (CRNI) - Infusion Nurses Certification Corporation (INCC)
  • Or
  • Chemotherapy Biotherapy Certificate (ONS/ONCC) - Oncology Nursing Society (ONS)
  • Or
  • Chemotherapy Immunotherapy Certificate (ONS/ONCC) - Oncology Nursing Society (ONS)
  • Or
  • Fundamentals of Chemotherapy Immunotherapy Certificate - Oncology Nursing Society (ONS)
  • Or
  • INS Fundamentals of Infusion Therapy (FIT) certification - Infusion Nurses Society (INS)
  • Or
  • Vascular Access Certification (VA-BC) - Vascular Access Certification Corporation (VACC)

State of Work Location: Wisconsin
  • Basic Life Support HealthCare Provider (BLS HCP) - American Heart Association (AHA)
  • And
  • Registered Nurse (RN) Issued by Compact State
  • Or
  • Registered Nurse (RN) - Wisconsin Department of Safety and Professional Services
  • And
  • Advanced Oncology Certified Nurse (AOCN) - Oncology Nursing Certification Corporation (ONCC)
  • Or
  • Anticoagulation Therapy Management Certification - University of Southern Indiana College of Nursing and Health Professions
  • Or
  • Certified Anticoagulation Care Provider (CACP) - National Certification Board for Anticoagulation Providers (NCBAP)
  • Or
  • Certified Oncology Nurse (OCN) - Oncology Nursing Certification Corporation (ONCC)
  • Or
  • Certified Pediatric Hematology Oncology Nurse (CPHON) - Oncology Nursing Certification Corporation (ONCC)
  • Or
  • Certified Pediatric Oncology Nurse (CPON) - Oncology Nursing Certification Corporation (ONCC)
  • Or
  • Certified Registered Nurse Infusion (CRNI) - Infusion Nurses Certification Corporation (INCC)
  • Or
  • Chemotherapy Biotherapy Certificate (ONS/ONCC) - Oncology Nursing Society (ONS)
  • Or
  • Chemotherapy Immunotherapy Certificate (ONS/ONCC) - Oncology Nursing Society (ONS)
  • Or
  • Fundamentals of Chemotherapy Immunotherapy Certificate - Oncology Nursing Society (ONS)
  • Or
  • INS Fundamentals of Infusion Therapy (FIT) certification - Infusion Nurses Society (INS)
  • Or
  • Vascular Access Certification (VA-BC) - Vascular Access Certification Corporation (VACC)

Work Shift:
Day Shift (United States of America)
Job Type:
Employee
Department:
3802000100 Infusion Center
Scheduled Weekly Hours:
24
Benefits:
SSM Health values our exceptional employees by offering a comprehensive benefits package to fit their needs.
  • Paid Parental Leave: we offer eligible team members one week of paid parental leave for newborns or newly adopted children (pro-rated based on FTE).
  • Flexible Payment Options: our voluntary benefit offered through DailyPay offers eligible hourly team members instant access to their earned, unpaid base pay (fees may apply) before payday.
  • Upfront Tuition Coverage: we provide upfront tuition coverage through FlexPath Funded for eligible team members.

Explore All Benefits
SSM Health is an equal opportunity employer. SSM Health does not discriminate on the basis of race, color, religion, national origin, age, disability, sex, sexual orientation, gender identity,pregnancy, veteran status, or any other characteristic protected by applicable law. Click here to learn more.

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