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Weekend Infusion Rn Jobs in Springfield, MO (NOW HIRING)

Position Details: Nurses work 12-hour shifts 7am-7pm or 7pm-7am with rotational weekends ... infusion/chemo, and anti-coagulation therapies. Why Mercy? From day one, Mercy offers outstanding ...

Nurses work 12-hour shifts 7am-7pm or 7pm-7am with rotational weekends. Full time or part time ... infusion/chemo, and anti-coagulation therapies. Why Mercy? From day one, Mercy offers outstanding ...

Nurses work 12-hour shifts 7am-7pm or 7pm-7am with rotational weekends. Full time or part time ... infusion/chemo, and anti-coagulation therapies. Why Mercy? From day one, Mercy offers outstanding ...

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Weekend Infusion Rn information

See Springfield, MO salary details

$10

$41

$75

How much do weekend infusion rn jobs pay per hour?

As of Jul 27, 2026, the average hourly pay for weekend infusion rn in Springfield, MO is $41.81, according to ZipRecruiter salary data. Most workers in this role earn between $33.03 and $45.72 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in the Weekend Infusion Rn position, and why are they important?

Weekend Infusion RNs require a current RN license, strong IV therapy skills, and experience in administering infusion medications safely. Familiarity with infusion pumps, electronic health records (EHR), and up-to-date certifications like Basic Life Support (BLS) or Advanced Cardiac Life Support (ACLS) are typically expected. Excellent organizational skills, compassionate bedside manner, and the ability to work independently are valuable soft skills in this setting. Mastery of these competencies ensures reliable, high-quality patient care during weekends when resources may be limited.

What is a Weekend Infusion RN job?

A Weekend Infusion RN is a registered nurse who administers intravenous (IV) therapies, medications, and treatments to patients during weekends. They work in outpatient clinics, hospitals, or home health settings, ensuring safe and effective infusion therapy. Responsibilities include monitoring patients for reactions, maintaining IV access, and educating patients about their treatments. This role requires strong IV skills, attention to detail, and the ability to work independently. It is ideal for nurses seeking flexible weekend hours while providing critical care to patients requiring infusion services.

What are the typical responsibilities and work environment for a Weekend Infusion RN?

As a Weekend Infusion RN, you will primarily administer intravenous medications, monitor patients for side effects, and educate them about their treatment plans—often in outpatient clinics, specialty centers, or sometimes patients' homes. The work environment is usually focused and patient-centered, with collaboration between RNs, pharmacists, and physicians, especially for complex cases. Since the role is concentrated on weekends, you may work more independently and manage a smaller, more specialized patient load. This schedule offers flexibility and the opportunity to focus on building relationships with patients receiving ongoing infusion therapy.

What are the most commonly searched types of Infusion Rn jobs in Springfield, MO? The most popular types of Infusion Rn jobs in Springfield, MO are:
What are popular job titles related to Weekend Infusion Rn jobs in Springfield, MO? For Weekend Infusion Rn jobs in Springfield, MO, the most frequently searched job titles are:
What cities near Springfield, MO are hiring for Weekend Infusion Rn jobs? Cities near Springfield, MO with the most Weekend Infusion Rn job openings:
Infographic showing various Weekend Infusion Rn job openings in Springfield, MO as of July 2026, with employment types broken down into 3% As Needed, 75% Full Time, 15% Part Time, and 7% Contract. Highlights an 95% Physical, 1% Hybrid, and 4% Remote job distribution, with an average salary of $86,966 per year, or $41.8 per hour.
RN - WEO Ambulatory Infusion Center

RN - WEO Ambulatory Infusion Center

CoxHealth

Springfield, MO • On-site

Full-time

Medical, Dental, Vision, Retirement

Posted 12 days ago


CoxHealth rating

6.6

Company rating: 6.6 out of 10

Based on 232 frontline employees who took The Breakroom Quiz

570th of 890 rated healthcare providers


Job description

Facility:
Wheeler Heart & Vascular: 3800 S National Ave, Springfield, Missouri, United States of America, 65807
Department:
1370 Ambulatory Infusion SGF
Scheduled Weekly Hours:
36
Hours:
06:30 AM-7:00 PM
Work Shift:
Day Shift (United States of America)
CoxHealth is a leading healthcare system serving 25 counties across southwest Missouri and northern Arkansas. The organization includes six hospitals, 5 ERs, and over 80 clinics. CoxHealth has earned the following honors for workplace excellence:
  • Named one of Modern Healthcare's Best Places to work five times.
  • Named one of America's Greatest Workplaces, Greatest Workplaces in Healthcare (2025, 2026), Greatest Workplaces for Women (2023, 2024), and Greatest Workplaces for Diversity (2024) by Newsweek and Plant-A Insights Group.
  • Acknowledged by Forbes as one of the Best Employers for New Grads.
  • Healthcare Innovation's Top Companies to Work for in Healthcare (2025).

Benefits
  • Medical, Vision, Dental, Retirement with Employer Match and more (20+ hrs/week)
  • For a comprehensive list of benefits, please click here: Benefits | CoxHealth

Job Description:
The Weekend Option Registered Nurse is responsible for managing the care of the patients experiencing medical conditions or surgical procedures. The nurse must be able to assess patient condition, administer medications, change dressings, monitor vital signs, keep records and provide patients and families with support and education. The Registered Nurse maintains a wide array of medical care knowledge in order to care for a diverse group of patients.
Education:
• Required: Graduate of an accredited nursing program or NLN approved program
• Preferred: Bachelor's Degree in Nursing
Experience:
• Preferred: Previous nursing experience
Skills:
• Excellent verbal and written communication skills
• Demonstrate effective leadership abilities
• Exhibits valuable time management skills
• Strong critical thinking/problem solving skills.
• Flexibility and ability to work in a multi-tasking environment.
Licensure/Certification/Registration
• Required: RN license active in the state of Missouri
Required: BLS must be obtained within 90 days of hire

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