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Weekend Infusion Rn Jobs in Springfield, MO (NOW HIRING)

CoxHealth

RN - WEO Ambulatory Infusion Center

Springfield, MO · On-site

  • Medical

  • Dental

  • Vision

  • Retirement

... Infusion SGF Scheduled Weekly Hours: 36 Hours: 06:30 AM-7:00 PM Work Shift: Day Shift (United ... Benefits | CoxHealth The Weekend Option Registered Nurse is responsible for managing the care of ...

CoxHealth

RN - WEO Ambulatory Infusion Center

Springfield, MO · On-site

  • Medical

  • Dental

  • Vision

  • Retirement

... Infusion SGF Scheduled Weekly Hours: 36 Hours: 06:30 AM-7:00 PM Work Shift: Day Shift (United ... Benefits | CoxHealth The Weekend Option Registered Nurse is responsible for managing the care of ...

Mercy

RN 7B Med Surg Weekends Full Time Nights

Springfield, MO · On-site

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

This position will work every weekend 7p-7a once off orientation. Incentives: * New Grad $5,000 ... infusion/chemo, and anti-coagulation therapies. Why Mercy? From day one, Mercy offers outstanding ...

Mercy

RN 7B Med Surg Weekends Full Time Nights

Springfield, MO · On-site

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

This position will work every weekend 7p-7a once off orientation. Incentives: * New Grad $5,000 ... infusion/chemo, and anti-coagulation therapies. Why Mercy? From day one, Mercy offers outstanding ...

Mercy

RN 7B Med Surg Weekends Full Time Nights

Springfield, MO · On-site

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

This position will work every weekend 7p-7a once off orientation. Incentives: * New Grad $5,000 ... infusion/chemo, and anti-coagulation therapies. Why Mercy? From day one, Mercy offers outstanding ...

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All JobsInfusion Rn JobsWeekend Infusion Rn JobsWeekend Infusion Rn Jobs in Springfield, MO

Weekend Infusion Rn information

See Springfield, MO salary details

$10

$41

$75

How much do weekend infusion rn jobs pay per hour?

As of Aug 17, 2026, the average hourly pay for weekend infusion rn in Springfield, MO is $41.81, according to ZipRecruiter salary data. Most workers in this role earn between $33.03 and $45.72 per hour, depending on experience, location, and employer.

What is a Weekend Infusion RN?

A Weekend Infusion RN is a registered nurse who administers intravenous (IV) therapies, medications, and treatments to patients during weekends. They work in outpatient clinics, hospitals, or home health settings, ensuring safe and effective infusion therapy. Responsibilities include monitoring patients for reactions, maintaining IV access, and educating patients about their treatments. This role requires strong IV skills, attention to detail, and the ability to work independently. It is ideal for nurses seeking flexible weekend hours while providing critical care to patients requiring infusion services.

What are the typical responsibilities and work environment for a Weekend Infusion RN?

As a Weekend Infusion RN, you will primarily administer intravenous medications, monitor patients for side effects, and educate them about their treatment plans—often in outpatient clinics, specialty centers, or sometimes patients' homes. The work environment is usually focused and patient-centered, with collaboration between RNs, pharmacists, and physicians, especially for complex cases. Since the role is concentrated on weekends, you may work more independently and manage a smaller, more specialized patient load. This schedule offers flexibility and the opportunity to focus on building relationships with patients receiving ongoing infusion therapy.

What are the key skills and qualifications needed to thrive in the Weekend Infusion RN position, and why are they important?

Weekend Infusion RNs require a current RN license, strong IV therapy skills, and experience in administering infusion medications safely. Familiarity with infusion pumps, electronic health records (EHR), and up-to-date certifications like Basic Life Support (BLS) or Advanced Cardiac Life Support (ACLS) are typically expected. Excellent organizational skills, compassionate bedside manner, and the ability to work independently are valuable soft skills in this setting. Mastery of these competencies ensures reliable, high-quality patient care during weekends when resources may be limited.

Do infusion nurses get paid more?

Infusion nurses often earn higher wages compared to general nursing roles due to specialized skills in administering IV therapies and managing complex patient needs. Their compensation can also increase with experience, certifications, and working in high-demand settings or during overtime and weekend shifts. However, pay varies by location, employer, and individual qualifications.

What are the most commonly searched types of Infusion Rn jobs in Springfield, MO?

The most popular types of Infusion Rn jobs in Springfield, MO are:

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For Weekend Infusion Rn jobs in Springfield, MO, the most frequently searched job titles are:

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What cities near Springfield, MO are hiring for Weekend Infusion Rn jobs?

Cities near Springfield, MO with the most Weekend Infusion Rn job openings:

Weekend Infusion Rn jobs near you
Infographic showing various Weekend Infusion Rn job openings in Springfield, MO as of August 2026, with employment types broken down into 1% As Needed, 65% Full Time, 30% Part Time, 3% Contract, and 1% Nights. Highlights an 94% Physical, 1% Hybrid, and 5% Remote job distribution, with an average salary of $86,966 per year, or $41.8 per hour.

Home Infusion Nurse (1+ year of ER, ICU or Infusion Experience)

Elevate Infusion

Bolivar, MO

$46 - $48/hr

Full-time, Contractor

Posted 5 days ago

Job description

Pay: $48.00 per hour

Job description:

Elevate Infusion Nursing Services is seeking a Contract RN Infusion Nurse to provide exceptional care for infusion patients. The ideal candidate will possess strong clinical skills, a passion for patient care, and the ability to work independently while maintaining high standards of safety and quality.

As an Infusion Nurse, you will deliver specialized medications and educate patients in the home setting. You will play a vital role in ensuring safe, effective, and compassionate care tailored to each patient’s needs.

Elevate Infusion Perks:

  • Flexible Schedule
  • Competitive Wages
  • Paid Drive Time
  • Independent Contractor Role

The Infusion Nurse provides primary patient care for specifically assigned patients to include assessment, care planning, evaluation and education of patients receiving infusion therapy and/or nursing services in accordance with the care matrices and best practices in the home setting.

Key Responsibilities include:

  • Ensuring the safe and effective delivery of these specialized medications.
  • Evaluate and educate patients and caregivers on administering infusion therapy safely.
  • Develop in conjunction with other team members the plan of care and evaluate response to therapy with each encounter.
  • Maintain scheduling and case management through the company's approved platform.
  • Communicate any scheduling changes on an as needed basis to appropriate team members.
  • Proficiently start peripheral intravenous line (PIV) and administer medications, such as IVIG or Biologics, in the home setting.
  • Submit thorough documentation within 24-48hrs of patient encounters.


Requirements

Qualifications:

  • Active and unrestricted RN license in the state of Missouri.
  • At least 2 years as RN with 1+ year in ER, ICU, or Infusion
  • At least 1 year of infusion or IV therapy experience (preferred).
  • Ability to independently start PIV lines and manage infusion therapy.
  • Strong organizational and communication skills.
  • Compassionate, patient-focused, and detail-oriented approach to care.


Benefits

Why Elevate Infusion?

Most of our nurses already have a full-time job — and that's perfectly fine. Elevate Infusion is built for RNs who want to earn meaningful extra income on their own schedule, without the burnout that comes with it.

What makes this different:

  • $48/hour for patient visit time and $35/hour for drive time — straightforward, competitive pay with no games
  • Truly flexible scheduling — you pick up visits that fit around your life, not the other way around
  • One patient at a time — no juggling 6 patients at once, no call lights going off down the hall, no chaos. Just you and your patient doing real clinical work
  • Work as much or as little as you want — whether that's a few visits a week or a full supplemental caseload, you control it
  • 1099 independent contractor status — you're running your own schedule like a professional
  • A chance to use your full skill set — IVIG and biologic infusions are high-acuity, clinically rewarding work that keeps your skills sharp

The bottom line:

Home infusion nursing is one of the best-kept secrets in the profession. The pay is better, the autonomy is real, and you'll finish a visit actually feeling good about the care you gave. If you've been looking for a way to earn more without burning out more, this is it.