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Weekend Infusion Rn Jobs in Spartanburg, SC (NOW HIRING)

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Weekend Infusion Rn information

See Spartanburg, SC salary details

$11

$44

$80

How much do weekend infusion rn jobs pay per hour?

As of Aug 20, 2026, the average hourly pay for weekend infusion rn in Spartanburg, SC is $44.91, according to ZipRecruiter salary data. Most workers in this role earn between $35.48 and $49.09 per hour, depending on experience, location, and employer.

What is a Weekend Infusion RN?

A Weekend Infusion RN is a registered nurse who administers intravenous (IV) therapies, medications, and treatments to patients during weekends. They work in outpatient clinics, hospitals, or home health settings, ensuring safe and effective infusion therapy. Responsibilities include monitoring patients for reactions, maintaining IV access, and educating patients about their treatments. This role requires strong IV skills, attention to detail, and the ability to work independently. It is ideal for nurses seeking flexible weekend hours while providing critical care to patients requiring infusion services.

What are the typical responsibilities and work environment for a Weekend Infusion RN?

As a Weekend Infusion RN, you will primarily administer intravenous medications, monitor patients for side effects, and educate them about their treatment plans—often in outpatient clinics, specialty centers, or sometimes patients' homes. The work environment is usually focused and patient-centered, with collaboration between RNs, pharmacists, and physicians, especially for complex cases. Since the role is concentrated on weekends, you may work more independently and manage a smaller, more specialized patient load. This schedule offers flexibility and the opportunity to focus on building relationships with patients receiving ongoing infusion therapy.

What are the key skills and qualifications needed to thrive in the Weekend Infusion RN position, and why are they important?

Weekend Infusion RNs require a current RN license, strong IV therapy skills, and experience in administering infusion medications safely. Familiarity with infusion pumps, electronic health records (EHR), and up-to-date certifications like Basic Life Support (BLS) or Advanced Cardiac Life Support (ACLS) are typically expected. Excellent organizational skills, compassionate bedside manner, and the ability to work independently are valuable soft skills in this setting. Mastery of these competencies ensures reliable, high-quality patient care during weekends when resources may be limited.

Do infusion nurses get paid more?

Infusion nurses often earn higher wages compared to general nursing roles due to specialized skills in administering IV therapies and managing complex patient needs. Their compensation can also increase with experience, certifications, and working in high-demand settings or during overtime and weekend shifts. However, pay varies based on location, employer, and individual qualifications.

What are the most commonly searched types of Infusion Rn jobs in Spartanburg, SC?

The most popular types of Infusion Rn jobs in Spartanburg, SC are:

What are popular job titles related to Weekend Infusion Rn jobs in Spartanburg, SC?

For Weekend Infusion Rn jobs in Spartanburg, SC, the most frequently searched job titles are:

What job categories do people searching Weekend Infusion Rn jobs in Spartanburg, SC look for?

The top searched job categories for Weekend Infusion Rn jobs in Spartanburg, SC are:

What cities near Spartanburg, SC are hiring for Weekend Infusion Rn jobs?

Cities near Spartanburg, SC with the most Weekend Infusion Rn job openings:

Infographic showing various Weekend Infusion Rn job openings in Spartanburg, SC as of August 2026, with employment types broken down into 13% As Needed, 62% Full Time, and 25% Part Time. Highlights an 100% In-person job distribution, with an average salary of $93,410 per year, or $44.9 per hour.

Full-time

Re-posted 4 days ago


Spartanburg Regional Healthcare System rating

6.7

Company rating: 6.7 out of 10

Based on 117 frontline employees who took The Breakroom Quiz

531st of 889 rated healthcare providers


Job description

Job Requirements

SIGN ON BONUS $10,000.00 Eligible Experienced RN

We are proud of our skilled, caring, trustworthy and compassionate Home Health experts. Our clinicians visit patient homes to deliver customized, physician-prescribed care after a hospital stay, illness or injury to rehabilitate and achieve optimal level of independence.  Home Health is an alternative to repeated hospitalizations or an extended hospital stay. Nurses and medical professionals work closely with primary care physicians and ensure patients are receiving optimum care tailored to individual needs.

  • 8:30 am-5:00 pm

Our Registered Nurses enjoy autonomy while caring for patients in their home environment. The team works with a wide variety of cases such as: Wound Care, Cardiac, Diabetes, Endocrine, Musculosketal, Pressure Ulcers, Infusion, etc. The average length of patient care is 47 days. 

The Registered Nurse provides skilled nursing services within the home care setting in accordance with the orders of a physician and under a plan of care. Through use of the nursing process, utilizes knowledge and skills at a competent level to provide direct age-specific and culturally appropriate patient care management in the homecare setting. The RN also serves as a clinical resource, participates in patient and staff education, demonstrates the use of independent nursing judgment, and serves as a preceptor. Develops and coordinates the plan of care and provides case management. Performs other duties as assigned.

Minimum Requirements

 Education

  • Graduate of an approved nursing program

 Experience

  • One (1) year of recent clinical nursing experience

License/Registration/Certifications

  • Current license to practice as a Registered Nurse in South Carolina
  • Valid SC driver's license with good driving record
  • CPR certification

 

 Core Job Responsibilities 

  • Responsible for continuous review of all aspects of patients on his/her caseload to include but not limited to: appropriate utilization of services; review of documentation in the medical record; maintenance of interdisciplinary communication and discharge planning.
  • Completes an initial assessment of patient and family to determine home care needs. Provides a complete physical assessment and history of current and previous illness(es) and medication reconciliation.
  • Collaborates with patients, families, and other members of the interdisciplinary care team to establish appropriate treatment plan and develop a plan of care.
  • Initiates the plan of care, makes necessary revisions as patient status, and needs change. Regularly re-evaluates patient nursing needs.
  • Initiates and facilitates interdisciplinary collaboration to enhance outcomes.
  • Initiates appropriate nursing interventions. Provides treatments as prescribed by the physician.
  • Provides health care instructions to the patient as appropriate per assessment and plan. Educates the patient and family/caregiver on self-care techniques medications, diet and other instructions as ordered.
  • Recognizes and utilizes opportunities for health counseling with patients and families/ caregivers.
  • Communicates with the physician regarding the patient's needs and reports changes in the patient's condition; communicates regularly with the interdisciplinary team; communicates with community health related persons to coordinate the plan of care; and communicates on a regular basis with manager.
  • Provides supervision of home health aides per regulatory requirements.
  • Complies with established policies and procedures.
  • Knowledge of and compliance with state, federal, and local regulations for the delivery of home care services.
  • Performs other duties as assigned.


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About Spartanburg Regional Healthcare System

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Spartanburg Regional Healthcare System is a leader in the healthcare industry, located in Spartanburg, SC, US. As a comprehensive health system, it offers services encompassing everything from wellness, prevention, and care coordination to specific medical treatments for a wide range of diseases and health issues. Spartanburg Regional Healthcare System was founded in 1921 and has since developed a reputation for excellence and innovative care, growing to include six hospitals, 100 medical offices, 8,000 associates and more than 900 medical staff.

Industry

Recruiting and staffing services

Company size

5,001 - 10,000 Employees

Headquarters location

Spartanburg, SC, US

Year founded

1921