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Weekend Infusion Rn Jobs in Spartanburg, SC (NOW HIRING)

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Weekend Infusion Rn information

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$11

$44

$80

How much do weekend infusion rn jobs pay per hour?

As of Aug 20, 2026, the average hourly pay for weekend infusion rn in Spartanburg, SC is $44.91, according to ZipRecruiter salary data. Most workers in this role earn between $35.48 and $49.09 per hour, depending on experience, location, and employer.

What is a Weekend Infusion RN?

A Weekend Infusion RN is a registered nurse who administers intravenous (IV) therapies, medications, and treatments to patients during weekends. They work in outpatient clinics, hospitals, or home health settings, ensuring safe and effective infusion therapy. Responsibilities include monitoring patients for reactions, maintaining IV access, and educating patients about their treatments. This role requires strong IV skills, attention to detail, and the ability to work independently. It is ideal for nurses seeking flexible weekend hours while providing critical care to patients requiring infusion services.

What are the typical responsibilities and work environment for a Weekend Infusion RN?

As a Weekend Infusion RN, you will primarily administer intravenous medications, monitor patients for side effects, and educate them about their treatment plans—often in outpatient clinics, specialty centers, or sometimes patients' homes. The work environment is usually focused and patient-centered, with collaboration between RNs, pharmacists, and physicians, especially for complex cases. Since the role is concentrated on weekends, you may work more independently and manage a smaller, more specialized patient load. This schedule offers flexibility and the opportunity to focus on building relationships with patients receiving ongoing infusion therapy.

What are the key skills and qualifications needed to thrive in the Weekend Infusion RN position, and why are they important?

Weekend Infusion RNs require a current RN license, strong IV therapy skills, and experience in administering infusion medications safely. Familiarity with infusion pumps, electronic health records (EHR), and up-to-date certifications like Basic Life Support (BLS) or Advanced Cardiac Life Support (ACLS) are typically expected. Excellent organizational skills, compassionate bedside manner, and the ability to work independently are valuable soft skills in this setting. Mastery of these competencies ensures reliable, high-quality patient care during weekends when resources may be limited.

Do infusion nurses get paid more?

Infusion nurses often earn higher wages compared to general nursing roles due to specialized skills in administering IV therapies and managing complex patient needs. Their compensation can also increase with experience, certifications, and working in high-demand settings or during overtime and weekend shifts. However, pay varies based on location, employer, and individual qualifications.

What are the most commonly searched types of Infusion Rn jobs in Spartanburg, SC?

The most popular types of Infusion Rn jobs in Spartanburg, SC are:

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For Weekend Infusion Rn jobs in Spartanburg, SC, the most frequently searched job titles are:

What job categories do people searching Weekend Infusion Rn jobs in Spartanburg, SC look for?

The top searched job categories for Weekend Infusion Rn jobs in Spartanburg, SC are:

What cities near Spartanburg, SC are hiring for Weekend Infusion Rn jobs?

Cities near Spartanburg, SC with the most Weekend Infusion Rn job openings:

Weekend Infusion Rn jobs near you
Infographic showing various Weekend Infusion Rn job openings in Spartanburg, SC as of August 2026, with employment types broken down into 13% As Needed, 62% Full Time, and 25% Part Time. Highlights an 100% In-person job distribution, with an average salary of $93,410 per year, or $44.9 per hour.

Registered Nurse (RN) Outpatient, Oncology Infusion, FT, Days (Float)

Prisma Health

Greenville, SC • On-site

Full-time

This job post has expired today. Applications are no longer accepted.

Prisma Health rating

7.1

Company rating: 7.1 out of 10

Based on 350 frontline employees who took The Breakroom Quiz

381st of 889 rated healthcare providers

Job description

Inspire health. Serve with compassion. Be the difference.
Job Summary
Provides therapies in the oncology setting, which includes, but is not limited to chemotherapy, immunotherapy, monoclonal antibody therapy, blood product transfusions, radiation therapy, and bone marrow transplant. Demonstrates clinical competency utilizing evidence-based practices/research in all areas of the nursing process: assessment, planning, implementation, evaluation, and outcomes. Incorporates knowledge of safety protocols, cost containment and quality improvement throughout the nursing process. Identifies patient, unit, and organizational priorities and incorporates the nursing process. Adheres to all compliance and policy and procedure requirements of the organization including, but not limited to licensure renewal, assigned training, employee health screenings, time and attendance policy, dress code policy, patient confidentiality, infection control, and medication administration. This job may require additional training and certifications such as ACLS, PALS, chemotherapy/biotherapy, and transplant/cellular therapy curriculum. Demonstrates knowledge of regulatory agency requirements (JCAHO, DHEC). Provides care within the scope of the SC Nursing Practice Act. This setting may require staff to be scheduled for shift, weekend, holiday, and on-call work.
Bonus
This position is bonus eligible. Follow this link for details
Essential Functions
  • All team members are expected to be knowledgeable and compliant with Prisma Health's purpose: Inspire health. Serve with compassion. Be the difference.
  • Assists physicians with examinations, procedures and other activities related to direct patient care.
  • Arranges for patient appointments for diagnostic testing, consults, referrals and admission to the hospital.
  • Monitors and maintains stock of medical supplies and proper functioning of equipment.
  • Documents patients' vital statistics and other encounter data into patient chart and ensures that all required records are in the chart. Obtains brief medical history and chief complaint from patients.
  • Calls in prescriptions for patients according to physician order.
  • Prepares exam rooms with appropriate instruments, supplies, and equipment. Cleans exam rooms between procedures and exams.
  • Receives and returns clinically related telephone calls, screening and forwarding those requiring physician action.
  • Completes medical/physical history forms and other related information for insurance companies.
  • Informs physician of changes in schedule.
  • Uses advanced level nursing skills and telephone triage guidelines to assess and prioritize different types of conditions and symptoms including when to call 911.
  • Performs other duties as assigned.

Supervisory/Management Responsibilities
  • This is a non-management job that will report to a supervisor, manager, director or executive.

Minimum Requirements
  • Education - Associate' degree in Nursing. Bachelor's degree in Nursing preferred.
  • Experience - One (1) year experience as a registered nurse.

In Lieu Of
  • In lieu of one (1) year of registered nurse experience, will accept successful completion of the Prisma Health Nurse Residency Program or successful completion of a comparable residency from another organization.
  • In lieu of one (1) year of registered nurse experience, will accept 1 year of licensed practical nurse (LPN) experience.

Required Certifications, Registrations, Licenses
  • Holds a current RN compact/multistate license recognized by the NCSBN Compact State or is licensed to practice as an RN in the state the team member is working.

Knowledge, Skills and Abilities
  • Working knowledge of Patient Equip (vitals, suction, defib)

Work Shift
Day (United States of America)
Location
Cancer Centers - Eastside
Facility
1008 Greenville Memorial Hospital
Department
10537179 Outpatient Oncology Infusion-CIEast
Share your talent with us! Our vision is simple: to transform healthcare for the benefits of the communities we serve. The transformation of healthcare requires talented individuals in every role here at Prisma Health.

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