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Weekend Infusion Rn Jobs in Charleston, SC (NOW HIRING)

Kids for the Future

Infusion RN

Summerville, SC · On-site

$65 - $90/hr

Employee Type FT Non-Exempt Articularis Healthcare Group (AHG) is currently seeking a full-time Infusion RN for Low Country Rheumatology. This position will be in West Ashley primarily but will be ...

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Helms Home Care Llc

PRN Infusion RN SC

Moncks Corner, SC · On-site

$55 - $83/hr

Helms Home Care is searching for registered nurses who can provide infusion therapy nursing services to patients in their homes and desire to serve patients with compassion and personalized care.

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Weekend Infusion Rn information

See Charleston, SC salary details

$10

$43

$77

How much do weekend infusion rn jobs pay per hour?

As of Sep 3, 2026, the average hourly pay for weekend infusion rn in Charleston, SC is $43.01, according to ZipRecruiter salary data. Most workers in this role earn between $33.99 and $47.02 per hour, depending on experience, location, and employer.

What is a Weekend Infusion RN?

A Weekend Infusion RN is a registered nurse who administers intravenous (IV) therapies, medications, and treatments to patients during weekends. They work in outpatient clinics, hospitals, or home health settings, ensuring safe and effective infusion therapy. Responsibilities include monitoring patients for reactions, maintaining IV access, and educating patients about their treatments. This role requires strong IV skills, attention to detail, and the ability to work independently. It is ideal for nurses seeking flexible weekend hours while providing critical care to patients requiring infusion services.

What are the typical responsibilities and work environment for a Weekend Infusion RN?

As a Weekend Infusion RN, you will primarily administer intravenous medications, monitor patients for side effects, and educate them about their treatment plans—often in outpatient clinics, specialty centers, or sometimes patients' homes. The work environment is usually focused and patient-centered, with collaboration between RNs, pharmacists, and physicians, especially for complex cases. Since the role is concentrated on weekends, you may work more independently and manage a smaller, more specialized patient load. This schedule offers flexibility and the opportunity to focus on building relationships with patients receiving ongoing infusion therapy.

What are the key skills and qualifications needed to thrive in the Weekend Infusion RN position, and why are they important?

Weekend Infusion RNs require a current RN license, strong IV therapy skills, and experience in administering infusion medications safely. Familiarity with infusion pumps, electronic health records (EHR), and up-to-date certifications like Basic Life Support (BLS) or Advanced Cardiac Life Support (ACLS) are typically expected. Excellent organizational skills, compassionate bedside manner, and the ability to work independently are valuable soft skills in this setting. Mastery of these competencies ensures reliable, high-quality patient care during weekends when resources may be limited.

Do infusion nurses get paid more?

Infusion nurses often earn higher wages compared to general nursing roles due to specialized skills in administering IV therapies and managing complex patient needs. Their compensation can also increase with experience, certifications, and working in high-demand settings or during overtime and weekend shifts. However, pay varies based on location, employer, and individual qualifications.

What are the most commonly searched types of Infusion Rn jobs in Charleston, SC?

The most popular types of Infusion Rn jobs in Charleston, SC are:

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For Weekend Infusion Rn jobs in Charleston, SC, the most frequently searched job titles are:

What job categories do people searching Weekend Infusion Rn jobs in Charleston, SC look for?

The top searched job categories for Weekend Infusion Rn jobs in Charleston, SC are:

What cities near Charleston, SC are hiring for Weekend Infusion Rn jobs?

Cities near Charleston, SC with the most Weekend Infusion Rn job openings:

Weekend Infusion Rn jobs near you
Infographic showing various Weekend Infusion Rn job openings in Charleston, SC as of June 2026, with employment types broken down into 76% Full Time, 20% Part Time, 3% Contract, and 1% Nights. Highlights an 95% Physical, 1% Hybrid, and 4% Remote job distribution, with an average salary of $89,470 per year, or $43 per hour.

Chemotherapy/Infusion Registered Nurse

Artemis Arc

Charleston, SC

$55/hr

Full-time

Re-posted 20 days ago

Key responsibilities

  • Assess, monitor, and treat patients receiving chemotherapy, immunotherapy, and infusion therapies.

  • Administer, monitor, document, and evaluate prescribed treatments such as chemotherapy, biotherapy, immunotherapy, blood products, and IV fluids.

  • Develop and implement patient education plans, address patient concerns, and coordinate care with interdisciplinary team members.

Job description

Requisition ID2026-4095Job SummaryJob Title:

Chemotherapy / Infusion Registered Nurse (RN)

Compensation: $55.00/hr plus benefits

Location

Charleston, SC VAMC - Chemotherapy & Infusion Suite(VA Medical Center / Outpatient Infusion Clinic)

Work Schedule

  • Clinic Coverage: Weekdays, weekends, and federal holidays as required

  • Shift Options:

    • Day Shift: 7:30 a.m. - 4:00 p.m.

    • Day Shift: 8:00 a.m. - 4:30 p.m.

    • Day Shift: 8:30 a.m. - 5:00 p.m.

Position Overview

The Chemotherapy / Infusion Registered Nurse (RN) is a highly skilled professional nurse who provides specialized nursing care to patients receiving chemotherapy, immunotherapy, and infusion-related treatments within the Chemotherapy & Infusion Suite. Under the supervision of the Nurse Manager, the Contract Chemotherapy/Infusion RN maintains accountability for coordinating and delivering safe, effective, and patient-centered care.

The RN provides care to individuals, families, and groups in accordance with the standards and ethical principles established by the American Nurses Association (ANA) and the Oncology Nursing Society (ONS). Contractor nurses are assigned based on patient care needs and individual experience.

Primary ResponsibilitiesDuties and ResponsibilitiesAssessment & Clinical Care

  • Identify and assess physiological, psychological, social, and environmental factors affecting patients undergoing chemotherapy and infusion therapy.

  • Demonstrate knowledge and skills appropriate to the care of adult and geriatric patients across all stages of treatment.

  • Assess, monitor, and treat patient responses to antineoplastic agents, immunotherapy, and infusion therapies.

  • Recognize and respond effectively to medical emergencies, infusion or transfusion reactions, and proactively intervene to prevent complications.

Medication & Treatment Administration

  • Administer, monitor, document, and evaluate chemotherapy, biotherapy, immunotherapy, blood products, iron infusions, antibiotics, IV fluids, and other prescribed treatments in accordance with ONS guidelines and medical center policies.

  • Perform venipuncture and manage vascular access devices including Port-A-Cath, PASport implanted devices, and PICC lines.

  • Safely manage chemotherapy spills and adhere to hazardous drug handling protocols.

  • Perform 12-lead electrocardiographic monitoring and interpret relevant laboratory values.

Advanced Nursing Skills

  • Provide Basic Life Support (BLS), airway management, and appropriate use of AED when indicated.

  • Perform tracheostomy care, gastrostomy/PEG tube care, urinary catheterization (indwelling and intermittent), blood glucose testing, and other diagnostic or therapeutic procedures as required.

  • Administer high-alert medications and oral or IV antineoplastic and immunotherapy agents as prescribed.

Documentation & Communication

  • Review electronic and/or paper medical records for provider orders and treatment protocols.

  • Document patient assessments, interventions, and outcomes using approved VA forms and computerized systems.

  • Promptly notify providers of significant changes in patient condition or other pertinent clinical information.

Patient Education & Care Coordination

  • Develop and implement individualized patient education and teaching plans based on assessed needs.

  • Address patient concerns, answer questions, and provide education regarding treatment plans, side effects, and self-care strategies.

  • Coordinate care and refer patients to other disciplines as appropriate, including nutrition, social work, and specialty services.

  • Collaborate with interdisciplinary team members to influence positive patient outcomes across the continuum of care.

Team & Operational Responsibilities

  • Work collaboratively with the Chemotherapy & Infusion team and participate in interdisciplinary meetings.

  • Maintain responsibility for providing clinical coverage to the Chemotherapy & Infusion Center.

  • Practice in adherence to professional nursing standards, ethical principles, and facility policies.

Special Assignments

  • May be required to care for COVID-19 positive patients and Patients Under Investigation (PUI) in the Chemotherapy/Infusion Clinic setting.

Minimum QualificationsQualificationsRequired

  • Active, unrestricted Registered Nurse (RN) license in a U.S. state, territory, or the District of Columbia.

  • Must have Assiocates in Nursing; BSN in Nursing is preffered
  • Must be ONC RN Certified 

  • Demonstrated experience in chemotherapy, infusion, oncology, or hematology nursing.

  • Ability to work independently and manage complex patient care in a fast-paced clinical environment.

  • Strong assessment, critical thinking, and emergency response skills.

Employment Type: OTHER

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